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Experimental arteriosclerosis. VIII. The effect of feeding olive oil on the absorption and deposition of cholesterol
SELECTED
381
ABSTRACTS
in the supine position and the table tilted so that the anterior surface of the foot was level When the femoral vein was occluded with the auricles was found to be 2 to 9 em. of water. by a blood clot, the venous pressure at the ankle was elevated. In one such patient the venous pressure at the ankle of the affected leg was 49 cm., whereas on the unaffected side the venous pressure was 2 centimeters. Following ligation of the femoral vein the venous pressure at the ankle was 60.5 centimeters. In several of the patients, the high venous pressure declined gradually following femoral ligation as collateral circulation improved. The fall in venous pressure was attended by a corresponding reduction of edema. NMDE. Member,
S., and Bruger, Olive Oil on the (Nov.-Dec.) 1945.
M.: Experimental Absorption and
Arteriosclerosis. VIII. Deposition of Cholesterol.
The Effect of Feeding Arch. Path. 40: 37Y
The authors found that when olive oil was added to the diet of rabbits in addition to cholesterol, the levels of blood cholesterol were slightly higher than when cholesterol was added alone. The deposition of cholesterol in the liver and the aorta was decidedly greater with the combination of olive oil and cholesterol than with cholesterol alone. N.%IDE. Grossman, New
C. M.: England
Pneumococcal J. Med. 233:
689
Pedcarditis Treated (Dec. 6) 1945.
With
Intrapericardial
Penicillin,
A case of pneumococcal pericarditis caused by Type VI11 pneumococcus is reported. The patient was a man, aged 30 years, who was treated with penicillin which was administered parentcrnlly and by intrapericardial injection. The first intrapericardial injection of penicillin consisted of 20,000 Oxford units. A second intrapericardial injeetiou of 15,000 units was made thirty-six hours later. Recovery was uneventful. Although the intrapericardial administration of penicillin was not regarded as unquestionably responsible for the cure, the author believes that this procedure is warranted by the fact that the treatment of pleural and synovial infertion is more successful when penicillin is used locally in additinu to the pnrenteral route. BEILET.
Crafoord, C., and Nylin, ment. J. Thoracic
G.: Surg.
Congenital 14: 347
Coarctation (Oct.) 1945.
of the
Aorta
and
Its
Surgical
Treat-
Two cases of coarctation of the aorta are reported in which surgical treatment was employed successfully. The patients were aged 12 and 27 years. The operation consisted of resection of the constricted part of the aorta and suture of the proximal and distal portions, The first operation was performed on Oct. 19, 1944, and the second on Oct. 31, 1944. Convalescence was uncomplicated in both cases. The patients wt’re re-examined in illarch, 1945, and at that time were in excellent health and had returned to their former duties. Hypertension had been replaced by normal blood pressure. The blood pressure in the legs had likewise returned within the normal range. The authors regard the operative results in these cast’s as evi(lence in favor of tllcz mer~hnni~al t,heory of the Cause of hypertension assoeialed rvltlr coarctatron of the aorta. BEI,T~ET.
Wedd,
A. M., and Blair, H. A.: The Action of Acetylcholine Turtle Ventricle. Am. J. Physiol. 145: 147 (Dec.) 1915.
and
Epinephrine
on
the
The action of acetylcholine on the turtle heart was investigated because in earlier work the refractory period was determined by a faulty method. The effect of acetylcholine on contractility was observed on ventricular strips suspended in a bath and stimulated rhythmically, the refractory period being determined from the Q-T interval of the electrocardiogram. Contraction height and diastolic length were decreased and the refractory period was slightly shortened. This action required much higher concentrations than those needed to produce the so-called inhibitory effects and was offset by atropine. It was believed to represent a direct action on myocardial fibers. The response to cnrbaminoylcholine (“Dory1 ‘I) was found to be similar to that of acetylcholine.
381
ABSTRACTS
in the supine position and the table tilted so that the anterior surface of the foot was level When the femoral vein was occluded with the auricles was found to be 2 to 9 em. of water. by a blood clot, the venous pressure at the ankle was elevated. In one such patient the venous pressure at the ankle of the affected leg was 49 cm., whereas on the unaffected side the venous pressure was 2 centimeters. Following ligation of the femoral vein the venous pressure at the ankle was 60.5 centimeters. In several of the patients, the high venous pressure declined gradually following femoral ligation as collateral circulation improved. The fall in venous pressure was attended by a corresponding reduction of edema. NMDE. Member,
S., and Bruger, Olive Oil on the (Nov.-Dec.) 1945.
M.: Experimental Absorption and
Arteriosclerosis. VIII. Deposition of Cholesterol.
The Effect of Feeding Arch. Path. 40: 37Y
The authors found that when olive oil was added to the diet of rabbits in addition to cholesterol, the levels of blood cholesterol were slightly higher than when cholesterol was added alone. The deposition of cholesterol in the liver and the aorta was decidedly greater with the combination of olive oil and cholesterol than with cholesterol alone. N.%IDE. Grossman, New
C. M.: England
Pneumococcal J. Med. 233:
689
Pedcarditis Treated (Dec. 6) 1945.
With
Intrapericardial
Penicillin,
A case of pneumococcal pericarditis caused by Type VI11 pneumococcus is reported. The patient was a man, aged 30 years, who was treated with penicillin which was administered parentcrnlly and by intrapericardial injection. The first intrapericardial injection of penicillin consisted of 20,000 Oxford units. A second intrapericardial injeetiou of 15,000 units was made thirty-six hours later. Recovery was uneventful. Although the intrapericardial administration of penicillin was not regarded as unquestionably responsible for the cure, the author believes that this procedure is warranted by the fact that the treatment of pleural and synovial infertion is more successful when penicillin is used locally in additinu to the pnrenteral route. BEILET.
Crafoord, C., and Nylin, ment. J. Thoracic
G.: Surg.
Congenital 14: 347
Coarctation (Oct.) 1945.
of the
Aorta
and
Its
Surgical
Treat-
Two cases of coarctation of the aorta are reported in which surgical treatment was employed successfully. The patients were aged 12 and 27 years. The operation consisted of resection of the constricted part of the aorta and suture of the proximal and distal portions, The first operation was performed on Oct. 19, 1944, and the second on Oct. 31, 1944. Convalescence was uncomplicated in both cases. The patients wt’re re-examined in illarch, 1945, and at that time were in excellent health and had returned to their former duties. Hypertension had been replaced by normal blood pressure. The blood pressure in the legs had likewise returned within the normal range. The authors regard the operative results in these cast’s as evi(lence in favor of tllcz mer~hnni~al t,heory of the Cause of hypertension assoeialed rvltlr coarctatron of the aorta. BEI,T~ET.
Wedd,
A. M., and Blair, H. A.: The Action of Acetylcholine Turtle Ventricle. Am. J. Physiol. 145: 147 (Dec.) 1915.
and
Epinephrine
on
the
The action of acetylcholine on the turtle heart was investigated because in earlier work the refractory period was determined by a faulty method. The effect of acetylcholine on contractility was observed on ventricular strips suspended in a bath and stimulated rhythmically, the refractory period being determined from the Q-T interval of the electrocardiogram. Contraction height and diastolic length were decreased and the refractory period was slightly shortened. This action required much higher concentrations than those needed to produce the so-called inhibitory effects and was offset by atropine. It was believed to represent a direct action on myocardial fibers. The response to cnrbaminoylcholine (“Dory1 ‘I) was found to be similar to that of acetylcholine.