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GIANT CELL TUMOR IN SINUS MAXILLARY AND NASAL CAVITY: A RARE CASE REPORT
ABSTRACTS
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Pleomorphic adenoma is the most common benign neoplasm of salivary glands, representing about 33% to 43% of tumors of the minor salivary gland. The palate is the most frequent intraoral site followed by the upper lip and the buccal mucosa. This report describes the development of pleomorphic adenoma in the infratemporal space in a 72-year-old woman. The lesion presented as a submucosal nodule, palpable deep in the left buccal mucosa. The computed tomography revealed a lobed hypodense formation partially obliterating the fat planes between the masseter and buccinator muscles. Surgical excision of the lesion was performed with histopathologic report of pleomorphic adenoma, and the patient is being followed up for 5 months with no signs of recurrence. It is important to note the unusual location and the importance of investigation and diagnostic elucidation for the correct therapeutic approach.
ADENOID CYSTIC CARCINOMA OF MINOR SALIVARY GLANDS: CASE REPORT. CAMILA OLIVEIRA SANTOS, ALYNE AMORIM DE ARAUJO, RODRIGO RESENDE, VANIA DO CARMO, LUISA AGUIRRE BUEXM, ADRIANA TEREZINHA NEVES NOVELLINO ALVES and, SIMONE DE QUEIROZ CHAVES LOURENCO ¸ Adenoid cystic carcinoma (ACC) is a malignant neoplasm of salivary glands that, with slow growth and infiltrative tumor, clinically is characterized by a firm mass. A 49-year-old brown female patient sought dental care with complaints of “headaches and nasal congestion over 10 months.” On the anamnesis she reported systemic arterial hypertension. Extraoral examination revealed facial asymmetry in the left maxillary region and absence of palpable lymph nodes. The intraoral examination revealed an increase in volume and ulcerated lesions in the left hard palate region. Radiopaque examination of the maxillary sinus and reabsorption of the 28 were performed on the radiographic examination. An incisional biopsy was performed with a diagnostic hypothesis of lymphoma. Histopathology reported an ACC. The patient was referred for oncologic treatment and will undergo subtotal maxillectomy with reconstruction by head and neck microsurgery. The biological aggressiveness of ACC is usually underestimated because of slow growth.
INTRAMUSCULAR HEMANGIOMA OF THE LOWER LIP. DANIEL CAETANO, FERNANDO LIMA, WLADIMIR CORTEZZI, BEATRIZ CORDEIRO, MICHELLE AGOSTINI, BRUNO AUGUSTO BENEVENUTO and, MARIO JOSE e ROMANACH Intramuscular hemangioma (IH) is relatively uncommon, accounting for less than 1% of all hemangiomas, usually located within the skeletal muscles of the trunk or limbs, particularly in the pelvic region. Approximately 10% of IH may occur in the head and neck region, most commonly affecting the masseter, sternocleidomastoid, and trapezius muscles. A 57-year-old man was referred for evaluation of a 4-cm asymptomatic, bluish, and slow-growing swelling of the lower lip. The patient’s history included lower lip trauma and bleeding 5 years earlier. The clinical differential diagnosis included mucocele, angioleiomyoma, and salivary gland tumor. The patient was submitted to excisional biopsy under general anesthesia. Microscopically, proliferating vascular channels lined by endothelium and smooth muscle were observed infiltrating diffusely skeletal muscles, adipose tissue, and connective tissue. The final diagnosis was IH.
OOOO January 2020 The patient is under regular follow-up with no recurrence. IH rarely affects the lips.
GRANULAR CELL TUMOR: CASE REPORT. HERIKA CRISTINA SILVA DE SOUZA, SIMONE HENRIQUES MACHADO, ANA e LEITE, ADRIANA FLAVIA SCHUELER DE ASSUMP¸C AO TEREZINHA NEVES NOVELLINO ALVES, LUCIANA WERNERSBACH PINTO and, SIMONE DE QUEIROZ CHAVES LOURENCO ¸ Patient D.S.O., a 38-year-old black woman who was a smoker for 27 years, sought dental care complaining of “a ball that appeared on the tongue after eating fish and the fishbone stuck into the tongue.” There was a gradual volumetric increase in region corresponding to the dorsum of the tongue for 5 years. On intraoral examination, a soft tissue nodule was found on the dorsum of the tongue, which was exophytic, sessile, single, welldelimited, elliptical, of firm consistency, smooth, white, asymptomatic, and measured about 5 cm. Preoperative laboratory testing was requested: complete blood count, coagulogram, and glucose, all with normal values. An excisional biopsy was performed for histopathologic examination. The clinical diagnosis was irritation fibroma. The histopathologic diagnosis was granular cell tumor. In the postoperative period there were no signs and symptoms. The granular cell tumor is rare tumor with the uncertain histogenesis and shows greater predilection for the oral cavity.
VASCULAR LEIOMYOMA: A RARE CASE REPORT IN THE BUCCAL MUCOSA. JAQUELINE LEMES RIBEIRO, FERNANDA HERRERA DA COSTA, RENATA MENDONCA ¸ MORAES, ANA SUELI RODRIGUES CAVALCANTE, ESTELA KAMINAGAKURA TANGO, YASMIN RODARTE CARVALHO and, ANA LIA ANBINDER Angioleiomyoma is a benign neoplasm with perivascular smooth muscle origin and is rare in the mouth. A male patient presented to our service with the chief complaint of an asymptomatic facial lesion. In the intraoral examination, a 1.5-cm submucosal nodule in the left cheek was observed. Doppler ultrasonography showed an image of a lobulated, hyperechoic nodule with defined limits and no change in the blood flow. The clinical hypotheses were lipoma, solitary fibrous tumor, and salivary gland neoplasm. Histologic examination after excisional biopsy revealed a delimited lesion, presenting multiple vascular spaces of varying sizes and calibers, sometimes congested and interconnected, covered by endothelium and spindle cell layers of variable thickness. A mixed thrombus with an organization area composed of granulation tissue was also found. Neoplastic cells were immunoreactive for smooth muscle actin and negative for CD34, confirming the diagnosis of angioleiomyoma. After 6 months of follow-up, no signs of recurrence were observed.
GIANT CELL TUMOR IN SINUS MAXILLARY AND NASAL CAVITY: A RARE CASE REPORT. BRENDO VINICIUS RODRIGUES LOUREDO, GERSON DE OLIVEIRA PAIVA NETO, ELIANDRO DE SOUZA FREITAS, FRANCISCO AMADIS BATISTA TATIANA NAYARA FERREIRA, FABIO ARRUDA BINDA, ^ LIBORIO-KIMURA and, JECONIAS CAMARA
OOOO Volume 129, Number 1 A 33-year-old male patient attended a surgical service reporting a swelling in the right nasal cavity for around 6 months. Magnetic resonance imaging showed a hypointense image on the upper wall of the right maxillary sinus invading the nasal cavity of the same side. There was a previous biopsy in the same region with an inconclusive diagnosis. The patient was submitted to excisional biopsy, and the surgical specimen was referred for a pathologic service with clinical suspicion of paraganglioma. Histopathologic examination evidenced a lesion characterized by proliferation of vascular spaces and fibroblastic cells with discrete collagen fibers and areas of hemorrhage surrounded by a large number of multinucleated giant cells, some with disorganized nuclei and others similar to Touton giant cells. A large proliferation of xanthomatous-looking cells was also observed. The diagnosis of giant cell tumor was established. Currently the patient is under follow-up with no signs of relapse.
DIFFUSE LARGE B-CELL LYMPHOMA OF ACTIVATED B-CELL-LIKE SUBGROUP AFFECTING THE PALATE. MARIA LETICIA DE ALMEIDA LANCA, ¸ JORGE ESQUICHE LEON, TULIO MORANDIM FERRISS, ALFREDO RIBEIRO-SILVA, FERNANDO CHAHUD, ANDREIA BUFALINO and, CLAUDIA MARIA NAVARRO Diffuse large B-cell lymphoma (DLBCL) is a non-Hodgkin lymphoma subtype constituted by diffuse proliferation of large neoplastic cells. The most commonly affected site in the head and neck is the Waldeyer ring, often involving adult and elderly patients. The World Health Organization classification recognizes germinal center B-cell like and activated B-cell like (ABC) molecular DLBCL subgroups, which differ in chromosomal alterations and clinical outcome. A 93-year-old female patient presented with an ulcer on the palate with 30 days of evolution and cervical mass rapidly growing in the last 15 days. An incisional biopsy was performed, and microscopic analysis revealed a DLBCL of ABC subgroup, showing immunopositivity for CD20, CD79 a, BCL-6, MUM-1, and BCL-2, and Ki67 was > 80%. She was submitted to palliative chemotherapy; however, she died 6 months later. DLBCL, especially the ABC subgroup, can follow an aggressive clinical course. Thus, early recognition is important to institute appropriate treatment with impact on prognosis.
METASTASIS OF COLON ADENOCARCINOMA TO ORAL CAVITY: A CASE REPORT. INGRID DA SILVA SANTOS, FREDERICO SAUERESSIG, BEATRIZ FARIAS VOGT, PEDRO BANDEIRA ALEIXO, SANDRA BEATRIZ CHAVES TARQUINIO, ANA PAULA NEUTZLING GOMES and, ISADORA LUANA FLORES Oral metastatic tumors are rare and usually indicate late stage of the disease. A 50-year-old female patient with previous medical history of treatment for colon adenocarcinoma 2 years earlier was referred for evaluation of an asymptomatic lesion with 1 month of evolution. Additionally, the patient was under investigation of bone metastasis. Extraoral examination did not detect lymph nodes. Intraoral examination revealed a pedunculated reddish-purple nodule measuring around 3.0 £ 2.0 cm in the gingiva of the posterior left maxilla with bleeding to palpation. Cone beam computed tomography showed bone loss
ABSTRACTS
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surrounding the molar region. An excisional biopsy was performed, and according to the microscopic and immunohistochemistry findings, the final diagnosis of colon adenocarcinoma metastasis was established. Metastasis in L2 vertebra also was confirmed. A palliative radiotherapy/chemotherapy was established; however, the patient died 1 month after the diagnosis. Metastatic tumors should be considered as differential diagnosis of oral lesions in patients with history of malignant neoplasms.
PLEOMORPHIC ADENOMA IN UNSUAL SITE: CASE REPORT. EALBER CARVALHO MACEDO LUNA, ERASMO BERNARDO MARINHO, STHEFANE GOMES FEITOSA, EVELINE TURATTI, ROBERTA BARROSO CAVALCANTE, FABRICIO BITU SOUSA and, KARUZA MARIA ALVES PEREIRA Pleomorphic adenoma is the benign tumor of salivary glands, which usually appears in the parotid gland, and when it affects minor glands it occurs mainly in the palate. This study presents a case report of male patient who presented to our service with slow-growing mass in the lip. Intraoral examination revealed nodule, which was sessile, well-circumscribed, covered by healthy mucosa, and located in the upper lip. Because of the well-circumscribed nature of the lesion and its clinical presentation, an excisional biopsy was performed with hypothesis of gland tumor. Microscopic examination revealed benign neoplasm of the salivary gland characterized by the proliferation of epithelial and myoepithelial cells arranged in sheets, cords, ductile structures, and small cellular clusters. Individually the cells exhibit oval or rounded vesicular nucleus with sparse and indistinct cytoplasm. There is abundant stromal or hyaline, sometimes myxoid or fibrous. The patient is under follow-up, and no sign of recurrence was observed for 1 year.
SQUAMOUS CELL CARCINOMA WITH A RHABDOID PHENOTYPE AFFECTING THE MAXILLA: CASE REPORT AND IMMUNOHISTOCHEMICAL ANALYSIS. LUCAS RIBEIRO TEIXEIRA, CASSIANO FRANCISCO WEEGE NONAKA, POLLIANNA MUNIZ ALVES, MANUEL ANTONIO e NEZ, GORDON-NU RODRIGO NEVES SILVA, XIOMARA BEATRIZ JIMENEZ POLANCO and, JORGE ESQUICHE LEON Squamous cell carcinoma (SCC) with a rhabdoid phenotype (SCCRP) is an extremely rare entity in the maxillofacial region. To date, only 2 oral SCCRP cases have been reported. The presence of this phenotype is associated with a worse prognosis than conventional SCC. A 44-year-old man was referred presenting painful facial asymmetry evidenced by increase of volume in the left maxilla with several months of evolution. Computerized tomography examination showed extensive osteolytic lesion on the left maxilla and maxillary sinus. The histopathologic analysis showed typical morphologic features of SCCRP constituted by polygonal and discohesive cells with large hyaline cytoplasmic inclusions and eccentric nuclei with single prominent nucleoli. Immunohistochemistry revealed positivity for CK AE1/AE3, epithelial membrane antigen (EMA), vimentin, CD138, INI-1, focally for a smooth muscle actin, and CD68. Ki-67 was > 40%. Although rare, SCCRP should be considered in the differential
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Pleomorphic adenoma is the most common benign neoplasm of salivary glands, representing about 33% to 43% of tumors of the minor salivary gland. The palate is the most frequent intraoral site followed by the upper lip and the buccal mucosa. This report describes the development of pleomorphic adenoma in the infratemporal space in a 72-year-old woman. The lesion presented as a submucosal nodule, palpable deep in the left buccal mucosa. The computed tomography revealed a lobed hypodense formation partially obliterating the fat planes between the masseter and buccinator muscles. Surgical excision of the lesion was performed with histopathologic report of pleomorphic adenoma, and the patient is being followed up for 5 months with no signs of recurrence. It is important to note the unusual location and the importance of investigation and diagnostic elucidation for the correct therapeutic approach.
ADENOID CYSTIC CARCINOMA OF MINOR SALIVARY GLANDS: CASE REPORT. CAMILA OLIVEIRA SANTOS, ALYNE AMORIM DE ARAUJO, RODRIGO RESENDE, VANIA DO CARMO, LUISA AGUIRRE BUEXM, ADRIANA TEREZINHA NEVES NOVELLINO ALVES and, SIMONE DE QUEIROZ CHAVES LOURENCO ¸ Adenoid cystic carcinoma (ACC) is a malignant neoplasm of salivary glands that, with slow growth and infiltrative tumor, clinically is characterized by a firm mass. A 49-year-old brown female patient sought dental care with complaints of “headaches and nasal congestion over 10 months.” On the anamnesis she reported systemic arterial hypertension. Extraoral examination revealed facial asymmetry in the left maxillary region and absence of palpable lymph nodes. The intraoral examination revealed an increase in volume and ulcerated lesions in the left hard palate region. Radiopaque examination of the maxillary sinus and reabsorption of the 28 were performed on the radiographic examination. An incisional biopsy was performed with a diagnostic hypothesis of lymphoma. Histopathology reported an ACC. The patient was referred for oncologic treatment and will undergo subtotal maxillectomy with reconstruction by head and neck microsurgery. The biological aggressiveness of ACC is usually underestimated because of slow growth.
INTRAMUSCULAR HEMANGIOMA OF THE LOWER LIP. DANIEL CAETANO, FERNANDO LIMA, WLADIMIR CORTEZZI, BEATRIZ CORDEIRO, MICHELLE AGOSTINI, BRUNO AUGUSTO BENEVENUTO and, MARIO JOSE e ROMANACH Intramuscular hemangioma (IH) is relatively uncommon, accounting for less than 1% of all hemangiomas, usually located within the skeletal muscles of the trunk or limbs, particularly in the pelvic region. Approximately 10% of IH may occur in the head and neck region, most commonly affecting the masseter, sternocleidomastoid, and trapezius muscles. A 57-year-old man was referred for evaluation of a 4-cm asymptomatic, bluish, and slow-growing swelling of the lower lip. The patient’s history included lower lip trauma and bleeding 5 years earlier. The clinical differential diagnosis included mucocele, angioleiomyoma, and salivary gland tumor. The patient was submitted to excisional biopsy under general anesthesia. Microscopically, proliferating vascular channels lined by endothelium and smooth muscle were observed infiltrating diffusely skeletal muscles, adipose tissue, and connective tissue. The final diagnosis was IH.
OOOO January 2020 The patient is under regular follow-up with no recurrence. IH rarely affects the lips.
GRANULAR CELL TUMOR: CASE REPORT. HERIKA CRISTINA SILVA DE SOUZA, SIMONE HENRIQUES MACHADO, ANA e LEITE, ADRIANA FLAVIA SCHUELER DE ASSUMP¸C AO TEREZINHA NEVES NOVELLINO ALVES, LUCIANA WERNERSBACH PINTO and, SIMONE DE QUEIROZ CHAVES LOURENCO ¸ Patient D.S.O., a 38-year-old black woman who was a smoker for 27 years, sought dental care complaining of “a ball that appeared on the tongue after eating fish and the fishbone stuck into the tongue.” There was a gradual volumetric increase in region corresponding to the dorsum of the tongue for 5 years. On intraoral examination, a soft tissue nodule was found on the dorsum of the tongue, which was exophytic, sessile, single, welldelimited, elliptical, of firm consistency, smooth, white, asymptomatic, and measured about 5 cm. Preoperative laboratory testing was requested: complete blood count, coagulogram, and glucose, all with normal values. An excisional biopsy was performed for histopathologic examination. The clinical diagnosis was irritation fibroma. The histopathologic diagnosis was granular cell tumor. In the postoperative period there were no signs and symptoms. The granular cell tumor is rare tumor with the uncertain histogenesis and shows greater predilection for the oral cavity.
VASCULAR LEIOMYOMA: A RARE CASE REPORT IN THE BUCCAL MUCOSA. JAQUELINE LEMES RIBEIRO, FERNANDA HERRERA DA COSTA, RENATA MENDONCA ¸ MORAES, ANA SUELI RODRIGUES CAVALCANTE, ESTELA KAMINAGAKURA TANGO, YASMIN RODARTE CARVALHO and, ANA LIA ANBINDER Angioleiomyoma is a benign neoplasm with perivascular smooth muscle origin and is rare in the mouth. A male patient presented to our service with the chief complaint of an asymptomatic facial lesion. In the intraoral examination, a 1.5-cm submucosal nodule in the left cheek was observed. Doppler ultrasonography showed an image of a lobulated, hyperechoic nodule with defined limits and no change in the blood flow. The clinical hypotheses were lipoma, solitary fibrous tumor, and salivary gland neoplasm. Histologic examination after excisional biopsy revealed a delimited lesion, presenting multiple vascular spaces of varying sizes and calibers, sometimes congested and interconnected, covered by endothelium and spindle cell layers of variable thickness. A mixed thrombus with an organization area composed of granulation tissue was also found. Neoplastic cells were immunoreactive for smooth muscle actin and negative for CD34, confirming the diagnosis of angioleiomyoma. After 6 months of follow-up, no signs of recurrence were observed.
GIANT CELL TUMOR IN SINUS MAXILLARY AND NASAL CAVITY: A RARE CASE REPORT. BRENDO VINICIUS RODRIGUES LOUREDO, GERSON DE OLIVEIRA PAIVA NETO, ELIANDRO DE SOUZA FREITAS, FRANCISCO AMADIS BATISTA TATIANA NAYARA FERREIRA, FABIO ARRUDA BINDA, ^ LIBORIO-KIMURA and, JECONIAS CAMARA
OOOO Volume 129, Number 1 A 33-year-old male patient attended a surgical service reporting a swelling in the right nasal cavity for around 6 months. Magnetic resonance imaging showed a hypointense image on the upper wall of the right maxillary sinus invading the nasal cavity of the same side. There was a previous biopsy in the same region with an inconclusive diagnosis. The patient was submitted to excisional biopsy, and the surgical specimen was referred for a pathologic service with clinical suspicion of paraganglioma. Histopathologic examination evidenced a lesion characterized by proliferation of vascular spaces and fibroblastic cells with discrete collagen fibers and areas of hemorrhage surrounded by a large number of multinucleated giant cells, some with disorganized nuclei and others similar to Touton giant cells. A large proliferation of xanthomatous-looking cells was also observed. The diagnosis of giant cell tumor was established. Currently the patient is under follow-up with no signs of relapse.
DIFFUSE LARGE B-CELL LYMPHOMA OF ACTIVATED B-CELL-LIKE SUBGROUP AFFECTING THE PALATE. MARIA LETICIA DE ALMEIDA LANCA, ¸ JORGE ESQUICHE LEON, TULIO MORANDIM FERRISS, ALFREDO RIBEIRO-SILVA, FERNANDO CHAHUD, ANDREIA BUFALINO and, CLAUDIA MARIA NAVARRO Diffuse large B-cell lymphoma (DLBCL) is a non-Hodgkin lymphoma subtype constituted by diffuse proliferation of large neoplastic cells. The most commonly affected site in the head and neck is the Waldeyer ring, often involving adult and elderly patients. The World Health Organization classification recognizes germinal center B-cell like and activated B-cell like (ABC) molecular DLBCL subgroups, which differ in chromosomal alterations and clinical outcome. A 93-year-old female patient presented with an ulcer on the palate with 30 days of evolution and cervical mass rapidly growing in the last 15 days. An incisional biopsy was performed, and microscopic analysis revealed a DLBCL of ABC subgroup, showing immunopositivity for CD20, CD79 a, BCL-6, MUM-1, and BCL-2, and Ki67 was > 80%. She was submitted to palliative chemotherapy; however, she died 6 months later. DLBCL, especially the ABC subgroup, can follow an aggressive clinical course. Thus, early recognition is important to institute appropriate treatment with impact on prognosis.
METASTASIS OF COLON ADENOCARCINOMA TO ORAL CAVITY: A CASE REPORT. INGRID DA SILVA SANTOS, FREDERICO SAUERESSIG, BEATRIZ FARIAS VOGT, PEDRO BANDEIRA ALEIXO, SANDRA BEATRIZ CHAVES TARQUINIO, ANA PAULA NEUTZLING GOMES and, ISADORA LUANA FLORES Oral metastatic tumors are rare and usually indicate late stage of the disease. A 50-year-old female patient with previous medical history of treatment for colon adenocarcinoma 2 years earlier was referred for evaluation of an asymptomatic lesion with 1 month of evolution. Additionally, the patient was under investigation of bone metastasis. Extraoral examination did not detect lymph nodes. Intraoral examination revealed a pedunculated reddish-purple nodule measuring around 3.0 £ 2.0 cm in the gingiva of the posterior left maxilla with bleeding to palpation. Cone beam computed tomography showed bone loss
ABSTRACTS
e83
surrounding the molar region. An excisional biopsy was performed, and according to the microscopic and immunohistochemistry findings, the final diagnosis of colon adenocarcinoma metastasis was established. Metastasis in L2 vertebra also was confirmed. A palliative radiotherapy/chemotherapy was established; however, the patient died 1 month after the diagnosis. Metastatic tumors should be considered as differential diagnosis of oral lesions in patients with history of malignant neoplasms.
PLEOMORPHIC ADENOMA IN UNSUAL SITE: CASE REPORT. EALBER CARVALHO MACEDO LUNA, ERASMO BERNARDO MARINHO, STHEFANE GOMES FEITOSA, EVELINE TURATTI, ROBERTA BARROSO CAVALCANTE, FABRICIO BITU SOUSA and, KARUZA MARIA ALVES PEREIRA Pleomorphic adenoma is the benign tumor of salivary glands, which usually appears in the parotid gland, and when it affects minor glands it occurs mainly in the palate. This study presents a case report of male patient who presented to our service with slow-growing mass in the lip. Intraoral examination revealed nodule, which was sessile, well-circumscribed, covered by healthy mucosa, and located in the upper lip. Because of the well-circumscribed nature of the lesion and its clinical presentation, an excisional biopsy was performed with hypothesis of gland tumor. Microscopic examination revealed benign neoplasm of the salivary gland characterized by the proliferation of epithelial and myoepithelial cells arranged in sheets, cords, ductile structures, and small cellular clusters. Individually the cells exhibit oval or rounded vesicular nucleus with sparse and indistinct cytoplasm. There is abundant stromal or hyaline, sometimes myxoid or fibrous. The patient is under follow-up, and no sign of recurrence was observed for 1 year.
SQUAMOUS CELL CARCINOMA WITH A RHABDOID PHENOTYPE AFFECTING THE MAXILLA: CASE REPORT AND IMMUNOHISTOCHEMICAL ANALYSIS. LUCAS RIBEIRO TEIXEIRA, CASSIANO FRANCISCO WEEGE NONAKA, POLLIANNA MUNIZ ALVES, MANUEL ANTONIO e NEZ, GORDON-NU RODRIGO NEVES SILVA, XIOMARA BEATRIZ JIMENEZ POLANCO and, JORGE ESQUICHE LEON Squamous cell carcinoma (SCC) with a rhabdoid phenotype (SCCRP) is an extremely rare entity in the maxillofacial region. To date, only 2 oral SCCRP cases have been reported. The presence of this phenotype is associated with a worse prognosis than conventional SCC. A 44-year-old man was referred presenting painful facial asymmetry evidenced by increase of volume in the left maxilla with several months of evolution. Computerized tomography examination showed extensive osteolytic lesion on the left maxilla and maxillary sinus. The histopathologic analysis showed typical morphologic features of SCCRP constituted by polygonal and discohesive cells with large hyaline cytoplasmic inclusions and eccentric nuclei with single prominent nucleoli. Immunohistochemistry revealed positivity for CK AE1/AE3, epithelial membrane antigen (EMA), vimentin, CD138, INI-1, focally for a smooth muscle actin, and CD68. Ki-67 was > 40%. Although rare, SCCRP should be considered in the differential