589
Recent books Cluster Analysis in Clinical Chemistry: A Model, by W. Vogt, D. Nagel and H. Sator. John Wiley Sons, Chichester, 1987, pp. 180, 2 24 The aim of this book is to show, through an explanation of the theory and the demonstration of a clinical example, how cluster analysis can aid clinical diagnosis. Disadvantages of the analysis are discussed as well as the benefits for the clinician who is required to interpret a mass of data. Heterocyclic Compounds. Synthesis of Fused Heterocycles, Vol. 47, by G. P. Ellis. A Wiley Interscience Publication, 1987, pp. 660, f. 140
ing drugs in the treatment and prophylaxis of angina pectoris are examined and the subject of diabetes is again addressed with the discovery of useful inhibitors of a dose reductase. In the face of ever broadening literature fronts, the worth of expertly composed reviews of vital research topics is highlighted yet again in this notable volume. Comprendre Presses d’envoi
et Apprendre
Universitaires FF 15,40
la Chimie
de Nancy,
Nancy,
Organique, 1987, pp.
par P. Caubke. 375, FF 85 4 frais
Each volume of the series The Chemistry of Heterocyclic Compounds deals with syntheses, reactions, properties, structures, physical chemistry and utility of compounds belonging to a specific ring system or class. This series has become the basic reference collection for information on heterocyclic compounds. This volume concerns methods for the synthesis of a heterocyclic ring which is fused to another ring. The first ring may be either homocyclic or heterocyclic and the second one is heterocyclic and contains 5-8 atoms at least 1 of which is nitrogen, oxygen or sulfur. 107 chapters are followed by appendix, list of books and monographs, references (up to 1986). A general index and an index of ring systems are very useful.
Ce cows r&dig& par Paul Caubdre, Professeur de Chimie Organique d I’UniversitP de Nancy I s’adresse aux e’tudiants abordant la chimie organique aprt?s les classes terminales. Le plan adopt6 vise ri n’introduire les diffirents concepts que progressivement de telle sorte que le lecteur ne soit pas krase’ par une avalanche de dkjinitions qu’il faudrait ensuite replacer dans le contexte de I’e’tude des fonctions. De plus, l’ensemble du texte a e’te’ class& en deux niveaux. L’objectif recherchP est quco I’ktudiant ne soit pas rebut6 en abordant trop t6t des notions ou r&actions qui lui paraitront tout d fait assimilables une fois acquises les connaissances du premier niveau. Et& plut& qu’un expose’ bref et concis, il a e’te’ choisi d’expliquer le plus possible chaque concept et &action afin de dkortiquer au mieux la demarche de pensie qu’il faut suivre pour aborder un probkme. Cet ouvrage est destine’ d aider les ktudiants d acqukir des bases solides en utilisant beaucoup plus la logique et la r@exion que la mkmoire.
Pharmacology and Applications of Chinese Materia Medica, by H.-M. Chang, P. Pui-Hay (translated by S. C.-S. Yeung, S. Cheng-Yao and L.-L. Wang). World Scientific Publishing Co., Ltd., Singapore, distributed by John Wiley & Sons, Ltd., 1987, pp. 775-1320, f. 69.25
Cancer da Sein - IXe Journt!es de la Socit%tCFrangaise de SYnologie et de Pathologie Mammaire, Responsable: D. Serin. Masson, Paris,
Volume 2 of the English edition of this comprehensive herbal drugs is, as volume 1, based on modern research and traditional Chinese medicine.
Dans ce volume publie’ par la SFSPM, on trouve le texte des expoks dPveloppant le theme des IXe Journ6es: Cancer du sein, DPjinition du risque me’tastatique, Bilan des thkapeutiques midicales adjuvantes.
book on Chinese pharmacological
Photon Emission from Biological Systems, by B. Jezowska-Trzebiatowska B. Kochel, J. Slawinski and W. Strek. World Scientific Publishing Co., Ltd., Singapore, distributed by John Wiley & Sons, Ltd., 1987, pp. 267, f. 31.10 This publication, consisting of the 16 lectures presented at the 1st International Symposium on Photon Emission from Biological Systems by a variety of researchers from 10 countries of Europe and Asia, is addressed at specialists whose disciplines are related to electromagnetic radiation and its role in biological systems. The spontaneous endogenous emission of low intensity electromagnetic radiation from diverse biological systems ranging from the basic biomolecules to man, is the central topic of lectures. Progress in Medicinal Chemistry 24, edited by G. P. Ellis and G. B. West. Elsevier, Amsterdam, 1987, pp. 360, Dfl 275.00 Eight fields representing important advances in the chemistry and biology of medicinal products are reviewed in this volume. The properties of ricin andits possible use in immunology are discussed. Another chapter reviews the evidence for functional histamine receptors in the mammalian central nervous system. The physiologically mysterious molybdenum-containing enzymes are examined. The anti-tumor activity of biologically active platinum complexes, the present medicinal use of Cannabis and cannabimimetic drugs, and the latest use of hypoglycemic agents in the treatment of insulin-resistant diabetic patients are further topics. The mechanisms of calcium channel block-
1987,
pp.
168,
235
F
Liposomes in Cell Biology and Pharmacology, by P. Machy and L. Leserman. Les Editions 1NSERM - John LlBBEY EUROTEXT, Paris London, 1987, pp. 192, FF 270,00, & 24.00 Published simultaneously in French and English versions, this Research In series encompasses all the fields of biomedical and health research in which French research and INSERM in particular holds an important international position. Liposomes are artificial vesicles consisting of one or more phospholipid bilayers. Drugs and other molecules may be transported in liposomes, either via encapsulation within their aqueous spaces or by association with their lipid membranes. In cell biology, liposomes are employed to transport biologically active molecules into cells and in the investigation of endocytosis. Various ligands, such as monoclonal antibodies to cell surface molecules, can be covalently coupled to liposomes making it possible to deliver the liposomes and their contents to selected cell populations. These properties of bulk transport and specific targeting have stimulated research into the therapeutic potential of liposomes. Liposomes in Cell Biology and Pharmacology offers a critical evaluation of more than 1000 published articles. The 1st section defines liposomes, describes their physicochemical properties and reviews the procedures for the preparation of liposomes of different types. The 2nd section examines approaches to the use of liposomes in therapy. The 3rd section presents methods of coupling specific ligands to liposomes and of studying their interaction with cells. In their concluding section the authors assess future applications of liposomes, especially in therapy.