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HLA-DPB1, -DQA1, -DQB1 and -DRB1 in a Slavic population from Northwest Russia
1067
Allele Gene frequency A*26 10.1 A*29 1.5 A*30 3.7 A*31 3.6 A*32 3.6 A*33 1.1 A*34 0.5 A*36 0.2 A*43 0.1 A*66 0.0 A*68 6.3 B*07 25.2 B*08 14.8 B*13 9.0 B*14 5.5 B*15 13.5 B*18 14.2 B*27 10.1 B*35 21.2 B*37 1.3 B*38 7.8 B*39 4.4 B*40 9.4 B*41 4.8 B*42 0.1 B*44 15.7 B*45 0.6 B*47 0.3 B*48 0.0 B*49 2.4 B*50 1.7 B*51 9.3 B*52 3.6 B*53 0.7 B*54 0.3 B*55 1.2 B*56 1.5 B*57 4.5 B*58 3.6 B*59 0.0 HLA hyplotype Frequency (%) Gene frequency DQA1*0101 30.8 0.173 DQA1*0102 26.9 0.141 DQA1*0103 25.6 0.135 DQA1*0201 23.1 0.122 DQA1*03 25.6 0.141 DQA1*0401 7.7 0.039 DQA1*05 50 0.25 DQA1*0601 0 0 DQB1*02 23.2 0.128 DQB1*0301 37.8 0.195 DQB1*0302 15.9 0.079 DQB1*0303 13.4 0.067 DQB1*0304 2.4 0.012 DQB1*04 2.4 0.012 DQB1*05 41.5 0.225 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA hyplotype Frequency (%) Gene frequency DQB1*0501 26.8 0.14 DQB1*06 50 0.274 DRB1*01 24 0.123 DRB1*03 16.5 0.087 DRB1*04 21.1 0.119 DRB1*07 27.5 0.146 DRB1*08 6.1 0.03 DRB1*09 2.3 0.012 DRB1*10 2.6 0.013 DRB1*11 22.3 0.114 DRB1*12 4.1 0.02 DRB1*13 23.7 0.124 DRB1*14 3.8 0.019 DRB1*15 28.3 0.155 DRB1*16 7.2 0.036
HLA-DPB1, -DQA1, -DQB1 and -DRB1 in a Slavic Population from Northwest Russia S. Kapustin*, A. Lyshchov, J. Alexandrova, E. Imyanitov and M. Blinov Research Institute of Haematology and Transfusiology, St. Petersburg, Russia E-mail: *[email protected] This population from Northwest, Russia, Latitude 58 – 64N Longitude 28 –35E consisted of 200 Caucasian individuals. The individuals came from an urban environment and HLA alleles were determined by sequence specific oligonucleotide probes. The results have previously been published in Tissue Antigens 54, 517–520, 1999. It was not possible to differentiate DRB1*0403 from 0406, DQA1*0101 from 0104 and DQB1*0604 from 0609. These frequencies are given under the first allele, respectively. Human Immunology 65, 1067–1068 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele DPB1*0101 DPB1*0201 DPB1*0202 DPB1*0301 DPB1*0401 DPB1*0402 DPB1*0501 DPB1*0601 DPB1*0801 DPB1*0901 DPB1*1001
Gene frequency 0.055 0.125 0.01 0.16 0.38 0.16 0.02 0.015 0.005 0.005 0.005 0198-8859/04/$–see front matter
1068
HLA allele Gene frequency DPB1*1101 0.01 DPB1*1301 0.015 DPB1*1401 0.01 DPB1*1501 0.01 DPB1*1901 0.005 DPB1*2601 0.005 DPB1*3501 0.005 DQA1*0101 0.155 DQA1*0102 0.185 DQA1*0103 0.085 DQA1*0201 0.105 DQA1*0301 0.16 DQA1*0401 0.045 DQA1*0501 0.265 DQB1*0201 0.175 DQB1*0301 0.2 DQB1*0302 0.11 DQB1*0303 0.05 DQB1*0402 0.04 DQB1*0501 0.13 DQB1*0502 0.065 DQB1*050301 0.025 DQB1*0601 0.015 DQB1*0602 0.095 DQB1*0603 0.06 DQB1*0604 0.035 DRB1*0101 0.088 DRB1*0102 0.023 DRB1*0103 0.01 DRB1*0301 0.095 DRB1*0401 0.06 DRB1*0402 0.005 DRB1*0403 0.045 DRB1*0404 0.023 DRB1*0407 0.005 DRB1*0410 0.005 DRB1*0701 0.12 DRB1*0801 0.023 DRB1*0803 0.013 DRB1*09 0.01 DRB1*1001 0.008 DRB1*1101 0.08 DRB1*1102 0.015 DRB1*1104 0.015 DRB1*1201 0.028 DRB1*1301 0.065 DRB1*1302 0.038 DRB1*1303 0.03 DRB1*1401 0.013 DRB1*1404 0.003 DRB1*1405 0.003 DRB1*1406 0.003 DRB1*1414 0.003 DRB1*1415 0.003 DRB1*1501 0.115 DRB1*150201 0.013 DRB1*150202 0.005 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA allele DRB1*1601 DRB1*1602 DRB1*1603
Gene frequency 0.028 0.013 0.003
HLA haplotype DRB1*0101-DQA1*0101-DQB1*0501 DRB1*0102-DQA1*0101-DQB1*0501 DRB1*0103-DQA1*0101-DQB1*0501 DRB1*0301-DQA1*0501-DQB1*0201 DRB1*0401-DQA1*0301-DQB1*0301 DRB1*0401-DQA1*0301-DQB1*0302 DRB1*0403-DQA1*0301-DQB1*0302 DRB1*0404-DQA1*0301-DQB1*0302 DRB1*0701-DQA1*0201-DQB1*0201 DRB1*0701-DQA1*0201-DQB1*0303 DRB1*0801-DQA1*0401-DQB1*0402 DRB1*0803-DQA1*0401-DQB1*0402 DRB1*0901-DQA1*0301-DQB1*0303 DRB1*1101-DQA1*0501-DQB1*0301 DRB1*1102-DQA1*0501-DQB1*0301 DRB1*1104-DQB1*0501-DQB1*0301 DRB1*1201-DQA1*0501-DQB1*0301 DRB1*1301-DQA1*0103-DQB1*0603 DRB1*1302-DQA1*0102-DQB1*0604 DRB1*1303-DQA1*0501-DQB1*0301 DRB1*1401-DQA1*0104-DQB1*05031 DRB1*1501-DQA1*0102-DQB1*0502 DRB1*1501-DQA1*0102-DQB1*0602 DRB1*15021-DQA1*0103-DQB1*0601 DRB1*1601-DQA1*0102-DQB1*0502 DRB1*1602-DQA1*0102-DQB1*0502
Frequency (%) 8.5 2.5 1 9 2 4 3 2 8 2.5 2.5 1.5 2 5.5 1 1.5 2.5 5.5 3 5 1.5 1.5 9 1 3 1
HLA-DQA1, -DQB1 and -DRB1 Alleles in a Population from Tuva Republic (Russia) J. Martinez-Laso, M. Sartakova, L. Allende, V. Konenkov, J. Moscoso, C. Silvera-Redondo, A. Pacho, J. Trapaga, E. Gomez-Casado and A. Arnaiz-Villena* Department of Immunology, Hospital 12 de Octubre, Facultad de Medicina Universidad Complutense, 28040 Madrid, Spain E-mail: *[email protected] This population from the Tuva Autonomic Republic in Asian Russia close to Altai Mountains and to the Yenisei river 0198-8859/04/$–see front matter
Allele Gene frequency A*26 10.1 A*29 1.5 A*30 3.7 A*31 3.6 A*32 3.6 A*33 1.1 A*34 0.5 A*36 0.2 A*43 0.1 A*66 0.0 A*68 6.3 B*07 25.2 B*08 14.8 B*13 9.0 B*14 5.5 B*15 13.5 B*18 14.2 B*27 10.1 B*35 21.2 B*37 1.3 B*38 7.8 B*39 4.4 B*40 9.4 B*41 4.8 B*42 0.1 B*44 15.7 B*45 0.6 B*47 0.3 B*48 0.0 B*49 2.4 B*50 1.7 B*51 9.3 B*52 3.6 B*53 0.7 B*54 0.3 B*55 1.2 B*56 1.5 B*57 4.5 B*58 3.6 B*59 0.0 HLA hyplotype Frequency (%) Gene frequency DQA1*0101 30.8 0.173 DQA1*0102 26.9 0.141 DQA1*0103 25.6 0.135 DQA1*0201 23.1 0.122 DQA1*03 25.6 0.141 DQA1*0401 7.7 0.039 DQA1*05 50 0.25 DQA1*0601 0 0 DQB1*02 23.2 0.128 DQB1*0301 37.8 0.195 DQB1*0302 15.9 0.079 DQB1*0303 13.4 0.067 DQB1*0304 2.4 0.012 DQB1*04 2.4 0.012 DQB1*05 41.5 0.225 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA hyplotype Frequency (%) Gene frequency DQB1*0501 26.8 0.14 DQB1*06 50 0.274 DRB1*01 24 0.123 DRB1*03 16.5 0.087 DRB1*04 21.1 0.119 DRB1*07 27.5 0.146 DRB1*08 6.1 0.03 DRB1*09 2.3 0.012 DRB1*10 2.6 0.013 DRB1*11 22.3 0.114 DRB1*12 4.1 0.02 DRB1*13 23.7 0.124 DRB1*14 3.8 0.019 DRB1*15 28.3 0.155 DRB1*16 7.2 0.036
HLA-DPB1, -DQA1, -DQB1 and -DRB1 in a Slavic Population from Northwest Russia S. Kapustin*, A. Lyshchov, J. Alexandrova, E. Imyanitov and M. Blinov Research Institute of Haematology and Transfusiology, St. Petersburg, Russia E-mail: *[email protected] This population from Northwest, Russia, Latitude 58 – 64N Longitude 28 –35E consisted of 200 Caucasian individuals. The individuals came from an urban environment and HLA alleles were determined by sequence specific oligonucleotide probes. The results have previously been published in Tissue Antigens 54, 517–520, 1999. It was not possible to differentiate DRB1*0403 from 0406, DQA1*0101 from 0104 and DQB1*0604 from 0609. These frequencies are given under the first allele, respectively. Human Immunology 65, 1067–1068 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele DPB1*0101 DPB1*0201 DPB1*0202 DPB1*0301 DPB1*0401 DPB1*0402 DPB1*0501 DPB1*0601 DPB1*0801 DPB1*0901 DPB1*1001
Gene frequency 0.055 0.125 0.01 0.16 0.38 0.16 0.02 0.015 0.005 0.005 0.005 0198-8859/04/$–see front matter
1068
HLA allele Gene frequency DPB1*1101 0.01 DPB1*1301 0.015 DPB1*1401 0.01 DPB1*1501 0.01 DPB1*1901 0.005 DPB1*2601 0.005 DPB1*3501 0.005 DQA1*0101 0.155 DQA1*0102 0.185 DQA1*0103 0.085 DQA1*0201 0.105 DQA1*0301 0.16 DQA1*0401 0.045 DQA1*0501 0.265 DQB1*0201 0.175 DQB1*0301 0.2 DQB1*0302 0.11 DQB1*0303 0.05 DQB1*0402 0.04 DQB1*0501 0.13 DQB1*0502 0.065 DQB1*050301 0.025 DQB1*0601 0.015 DQB1*0602 0.095 DQB1*0603 0.06 DQB1*0604 0.035 DRB1*0101 0.088 DRB1*0102 0.023 DRB1*0103 0.01 DRB1*0301 0.095 DRB1*0401 0.06 DRB1*0402 0.005 DRB1*0403 0.045 DRB1*0404 0.023 DRB1*0407 0.005 DRB1*0410 0.005 DRB1*0701 0.12 DRB1*0801 0.023 DRB1*0803 0.013 DRB1*09 0.01 DRB1*1001 0.008 DRB1*1101 0.08 DRB1*1102 0.015 DRB1*1104 0.015 DRB1*1201 0.028 DRB1*1301 0.065 DRB1*1302 0.038 DRB1*1303 0.03 DRB1*1401 0.013 DRB1*1404 0.003 DRB1*1405 0.003 DRB1*1406 0.003 DRB1*1414 0.003 DRB1*1415 0.003 DRB1*1501 0.115 DRB1*150201 0.013 DRB1*150202 0.005 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA allele DRB1*1601 DRB1*1602 DRB1*1603
Gene frequency 0.028 0.013 0.003
HLA haplotype DRB1*0101-DQA1*0101-DQB1*0501 DRB1*0102-DQA1*0101-DQB1*0501 DRB1*0103-DQA1*0101-DQB1*0501 DRB1*0301-DQA1*0501-DQB1*0201 DRB1*0401-DQA1*0301-DQB1*0301 DRB1*0401-DQA1*0301-DQB1*0302 DRB1*0403-DQA1*0301-DQB1*0302 DRB1*0404-DQA1*0301-DQB1*0302 DRB1*0701-DQA1*0201-DQB1*0201 DRB1*0701-DQA1*0201-DQB1*0303 DRB1*0801-DQA1*0401-DQB1*0402 DRB1*0803-DQA1*0401-DQB1*0402 DRB1*0901-DQA1*0301-DQB1*0303 DRB1*1101-DQA1*0501-DQB1*0301 DRB1*1102-DQA1*0501-DQB1*0301 DRB1*1104-DQB1*0501-DQB1*0301 DRB1*1201-DQA1*0501-DQB1*0301 DRB1*1301-DQA1*0103-DQB1*0603 DRB1*1302-DQA1*0102-DQB1*0604 DRB1*1303-DQA1*0501-DQB1*0301 DRB1*1401-DQA1*0104-DQB1*05031 DRB1*1501-DQA1*0102-DQB1*0502 DRB1*1501-DQA1*0102-DQB1*0602 DRB1*15021-DQA1*0103-DQB1*0601 DRB1*1601-DQA1*0102-DQB1*0502 DRB1*1602-DQA1*0102-DQB1*0502
Frequency (%) 8.5 2.5 1 9 2 4 3 2 8 2.5 2.5 1.5 2 5.5 1 1.5 2.5 5.5 3 5 1.5 1.5 9 1 3 1
HLA-DQA1, -DQB1 and -DRB1 Alleles in a Population from Tuva Republic (Russia) J. Martinez-Laso, M. Sartakova, L. Allende, V. Konenkov, J. Moscoso, C. Silvera-Redondo, A. Pacho, J. Trapaga, E. Gomez-Casado and A. Arnaiz-Villena* Department of Immunology, Hospital 12 de Octubre, Facultad de Medicina Universidad Complutense, 28040 Madrid, Spain E-mail: *[email protected] This population from the Tuva Autonomic Republic in Asian Russia close to Altai Mountains and to the Yenisei river 0198-8859/04/$–see front matter