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Human interleukin 2 by recombinant DNA technique
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Hospital, London SE1 7EH, U.K., Telephone: (01) 928-9292, Ext. 3136; or Dr. B.W. Papermaster, Cancer Research Center, Columbia, MO 65205, Telephone: (314) 8752255. Further announcements about the work of the Lymphokine Standardization Subcommittee will appear shortly.
JIM 03215
Biotechnological News
Human Interleukin 2 by Recombinant DNA Technique The synthesis of fully functional IL-2, induced in E. coli with complementary D N A from human leukaemic T cells, has been achieved by S.A. Rosenberg and E.A. G r i m m of the National Cancer Institute, Bethesda, MD, in collaboration with M. McGrogan et al. of Cetus Corp. (Science, 1984, 223, 1412).
JIM 03227
Immunotherapeutic News
Cancer Cells Removed with Antibody-Linked Magnetic Microspheres A cell separation technique employing magnetite-containing polystyrene microspheres conjugated with anti-neuroblastoma cell monoclonal antibodies has been applied to remove neuroblastoma cells from bone marrow by John T. Kemshead of the Imperial Cancer Research Fund's oncology laboratory at the Institute of Child Health in London, in collaboration with Alan R e m b a u m of the Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA. The method for preparing antibody-coupled magnetic microspheres was described in 1979 by S. Margel, S. Zisblatt and A. R e m b a u m in this journal, Vo. 28, pp. 341-353.
Hospital, London SE1 7EH, U.K., Telephone: (01) 928-9292, Ext. 3136; or Dr. B.W. Papermaster, Cancer Research Center, Columbia, MO 65205, Telephone: (314) 8752255. Further announcements about the work of the Lymphokine Standardization Subcommittee will appear shortly.
JIM 03215
Biotechnological News
Human Interleukin 2 by Recombinant DNA Technique The synthesis of fully functional IL-2, induced in E. coli with complementary D N A from human leukaemic T cells, has been achieved by S.A. Rosenberg and E.A. G r i m m of the National Cancer Institute, Bethesda, MD, in collaboration with M. McGrogan et al. of Cetus Corp. (Science, 1984, 223, 1412).
JIM 03227
Immunotherapeutic News
Cancer Cells Removed with Antibody-Linked Magnetic Microspheres A cell separation technique employing magnetite-containing polystyrene microspheres conjugated with anti-neuroblastoma cell monoclonal antibodies has been applied to remove neuroblastoma cells from bone marrow by John T. Kemshead of the Imperial Cancer Research Fund's oncology laboratory at the Institute of Child Health in London, in collaboration with Alan R e m b a u m of the Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA. The method for preparing antibody-coupled magnetic microspheres was described in 1979 by S. Margel, S. Zisblatt and A. R e m b a u m in this journal, Vo. 28, pp. 341-353.