JID VisualDx Quiz: June 2014

JID VisualDx Quiz: June 2014

JID VisualDx Quiz JID VisualDx Quiz: June 2014 Eric Lee1 and Robert S. Kirsner1 Journal of Investigative Dermatology (2014) 134, e17. doi:10.1038/jid...

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JID VisualDx Quiz

JID VisualDx Quiz: June 2014 Eric Lee1 and Robert S. Kirsner1 Journal of Investigative Dermatology (2014) 134, e17. doi:10.1038/jid.2014.183

JID and Logical Images, Inc., have cooperated to offer the JID VisualDx Quiz, incorporating diagnostic images from VisualDx’s vast database. Questions relate to the image as well as to selected articles in JID, which are listed after the questions. Answers will be posted as supplementary material. We hope you enjoy this challenge.

Image appears with permission from VisualDx. © Logical Images, Inc.

QUESTIONS 1.  What is your diagnosis?  a.  Lichen planus.  b.  Pruritus ani.  c.  Psoriasis.  d.  Paget’s disease.  e.  Contact dermatitis.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA

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© 2014 The Society for Investigative Dermatology

www.jidonline.org

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JID VisualDx Quiz

2. What is the function of aquaporin-3?  a. Adheres cells.  b. Transports water.  c. Delivers sodium.  d. Signals inflammation.  e.  None of the above.

3. Which is true about aquaporin-3?  a.  It fluctuates rhythmically over 24 hours.  b.  It is expressed in keratinocytes.  c.  Aquaporin gene expression in humans is regulated by CLOCK/BMAL1.  d.  Its transport may be affected by pH.  e.  All of the above.

TOPIC ARTICLE Questions 2 and 3 refer to the following article: Matsunaga N, Itcho K, Hamamura K et al. (2014) 24-Hour rhythm of aquaporin-3 function in the epidermis is regulated by molecular clocks. J Invest Dermatol 134:1636–44

Answers are available as supplementary material at http:dx.doi.org/10.1038/jid.2014.183

Additional images related to this condition and the differential diagnosis may be found at http://info.visualdx.com/l/11412/2014-04-16/vtmby.

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Journal of Investigative Dermatology (2014), Volume 134

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