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LB023-MON BENEFICIAL EFFECT OF CLASSICAL JAPANESE FOOD “MISO” ON ENTERAL NUTRITION-RELATED DIARRHEA
274 LB022-MON EFFECTS OF SWEET SUBSTANCE DEPENDENCE (SSD) IN PLASMA LEVELS OF LEPTIN IN WOMEN D.M. Macedo1 , R.W. Diez-Garcia1 , A.A. Jord˜ ao J´ unior1 . 1 Department of Clinical Medicine, Faculty of Medicine of Ribeirao Preto, University of S˜ ao Paulo/USP, Ribeir˜ ao Preto, Brazil Introduction: The SSD and high levels of leptin seem to further activate the mesolimbic brain region. Objective: To characterize the SSD and compare the plasma levels of leptin between women with and without SSD. Methods: The SSD was identified through the “You have felt a strong desire to eat sweet in the last three months” [1] and the sample was divided into two groups (with and without SSD). We used the “Questionnaire for Assessing Abuse and Dependence Sugar” [2] to characterize the SSD, and qualitative questions to map the consumption of sugars. The baseline plasma levels of leptin were measured and compared between groups. Results: Fifty-seven women participated in the study, 32 with SSD (56,14%) and 25 without SSD (43,86%). Comparing women with and without SSD, the most women with SSD using the candy to improve mood (p < 0.01), increasing amounts to feel good (p < 0.01), feel symptoms in the absence of sweets (p < 0.01), eat more sweets than intended (p < 0.01), they had tried but failed to stop or reduce the consumption of sweets; spend hours thinking about how to acquire them (p < 0.01); they have stopped doing any activity to be eating sweets (p < 0.01); and still eating these foods even though it can cause problems (p < 0.01). The variety, the amount of sweets, and eating behaviors observed were different between the groups. The mean plasma levels of leptin was significantly higher among women with SSD (p < 0.01). Conclusion: Women with SSD showed peculiar behavior related to the search for sweets and increased plasma levels of leptin. References [1] Weingarten H.P.; Elston, C. Food cravings in a college population. Appetite, London, v. 17, n. 3, p. 167 175, 1991. [2] Rosa, M.A.C.; Slavutzky, S.M.B.; Pechansky, F.; Kessler, F. Processo de desenvolvimento de um question´ ario para avalia¸ ca ˜o de abuso e dependˆ encia de a¸ cu ´car. Caderno de Sa´ ude P´ ublica, Rio de Janeiro, v. 24, n. 8, p. 1869 1876, 2008. Disclosure of Interest: None Declared
LB023-MON BENEFICIAL EFFECT OF CLASSICAL JAPANESE FOOD “MISO” ON ENTERAL NUTRITION-RELATED DIARRHEA M. Kawaguchi1 , H. Fujii1 , J. Hirai1 , Y. Hashimoto1 , A. Sumi1 , A. Hara1 , R. Naora1 , A. Kubota1 , S. Yano1 . 1 Nutrition Support Center, Shimane University Faculty of Medicine, Izumo, Japan Rationale: Severe diarrhea sometimes occurs after enteral nutrition (EN) and is still difficult to treat. “Miso”, which is made from soy beans, rice, salt, and the specific ferment, is commonly used for classical Japanese food like “miso-soup”. We took note of its tuning potential for
Late Breaking Abstracts the digestive function and examined to see the effects of “miso” on EN-related diarrhea and on the acceptance of EN therapy. Methods: Eighty-eight patients (59 males, 27 females; mean age 71.7 and 75.5, respectively) who had diarrhea (several times or more a day) during EN therapy and did not recover from it by the conventional therapy, agreed to participate in this study. A cup of “miso-soup” (100 mL) was infused 2 or 3 times a day just before the EN infusion. Antibiotics were given in 70 patients and GFO (glutamine, fiber, and oligo-saccharide) was supplied in 28 patients. EN had been stopped in 6 patients. The EN access was nasogastric tubing, gastrostomy, and jejunostomy, in 42, 19, and 10 patients, respectively. “Miso-soup” was cooked by boil the 300 g of vegetables and fruits in 1 L of water for 3 hours and addition of “miso” (8 g per 100 mL). Results: The “miso-soup” therapy made it possible to continue EN in 86 patients. Eighty patients tended to recover from diarrhea within 4 days after the “miso-soup” infusion. Twenty patients showed significant recovery among 28 patients, who did not recover from diarrhea by the GFO therapy. Six patients, who had once refused EN therapy, could restart it, because they were cured of diarrhea. It was also noteworthy that no one aggravated diarrhea by “miso-soup” infusion. Conclusion: The “miso-soup” therapy seems to be more effective than conventional therapies for EN-related diarrhea. Further study is necessary to clarify the benefit of “miso” as a functional food. Disclosure of Interest: None Declared
LB024-MON ASSOCIATION BETWEEN COFFEE CONSUMPTION AND CHRONIC KIDNEY DISEASE IN KOREAN WOMEN WITH AND WITHOUT DIABETES; ANALYSIS OF THE FOURTH KOREA NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY IN 2008 B.H. Kim1 , J.K. Lee1 , H.-M. Noh1 , Y.S. Park2 , I.H. Kim1 . 1 Family Medicine, Samsung Medical Center, 2 Family Medicine, Kangbuk Samsung Hospital, Seoul, Korea, Republic Of Rationale: In previous studies showed coffee consumption has protective effect for development of diabetes by components of coffee act as antioxidants and enhancing insulin sensitivity [1] and also, beneficial effect on cardiovascular disorder by inverse association with markers of inflammation and endothelial dysfunction in American diabetic women [2]. The aim of this study is to investigate the relationship between habitual coffee consumption and CKD in Korean women. Methods: This study involved 2,673 women aged 35 to 64 years in the Fourth Korea National Health and Nutrition Examination Surveys conducted in 2008. Habitual coffee consumption classified into three categories; less than 1 cup per day, 1 cup per day, and 2 or more cups per day. CKD was defined as estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m2 by MDRD equation. Results: Compared with drinking less than 1 cup of coffee per day, the odds ratio (OR) for CKD was 0.586 (confidence interval [CI], 0.367 0.937; P = 0.026) of habitual drinking 2 or more cups per day after adjusting for multiple
LB023-MON BENEFICIAL EFFECT OF CLASSICAL JAPANESE FOOD “MISO” ON ENTERAL NUTRITION-RELATED DIARRHEA M. Kawaguchi1 , H. Fujii1 , J. Hirai1 , Y. Hashimoto1 , A. Sumi1 , A. Hara1 , R. Naora1 , A. Kubota1 , S. Yano1 . 1 Nutrition Support Center, Shimane University Faculty of Medicine, Izumo, Japan Rationale: Severe diarrhea sometimes occurs after enteral nutrition (EN) and is still difficult to treat. “Miso”, which is made from soy beans, rice, salt, and the specific ferment, is commonly used for classical Japanese food like “miso-soup”. We took note of its tuning potential for
Late Breaking Abstracts the digestive function and examined to see the effects of “miso” on EN-related diarrhea and on the acceptance of EN therapy. Methods: Eighty-eight patients (59 males, 27 females; mean age 71.7 and 75.5, respectively) who had diarrhea (several times or more a day) during EN therapy and did not recover from it by the conventional therapy, agreed to participate in this study. A cup of “miso-soup” (100 mL) was infused 2 or 3 times a day just before the EN infusion. Antibiotics were given in 70 patients and GFO (glutamine, fiber, and oligo-saccharide) was supplied in 28 patients. EN had been stopped in 6 patients. The EN access was nasogastric tubing, gastrostomy, and jejunostomy, in 42, 19, and 10 patients, respectively. “Miso-soup” was cooked by boil the 300 g of vegetables and fruits in 1 L of water for 3 hours and addition of “miso” (8 g per 100 mL). Results: The “miso-soup” therapy made it possible to continue EN in 86 patients. Eighty patients tended to recover from diarrhea within 4 days after the “miso-soup” infusion. Twenty patients showed significant recovery among 28 patients, who did not recover from diarrhea by the GFO therapy. Six patients, who had once refused EN therapy, could restart it, because they were cured of diarrhea. It was also noteworthy that no one aggravated diarrhea by “miso-soup” infusion. Conclusion: The “miso-soup” therapy seems to be more effective than conventional therapies for EN-related diarrhea. Further study is necessary to clarify the benefit of “miso” as a functional food. Disclosure of Interest: None Declared
LB024-MON ASSOCIATION BETWEEN COFFEE CONSUMPTION AND CHRONIC KIDNEY DISEASE IN KOREAN WOMEN WITH AND WITHOUT DIABETES; ANALYSIS OF THE FOURTH KOREA NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY IN 2008 B.H. Kim1 , J.K. Lee1 , H.-M. Noh1 , Y.S. Park2 , I.H. Kim1 . 1 Family Medicine, Samsung Medical Center, 2 Family Medicine, Kangbuk Samsung Hospital, Seoul, Korea, Republic Of Rationale: In previous studies showed coffee consumption has protective effect for development of diabetes by components of coffee act as antioxidants and enhancing insulin sensitivity [1] and also, beneficial effect on cardiovascular disorder by inverse association with markers of inflammation and endothelial dysfunction in American diabetic women [2]. The aim of this study is to investigate the relationship between habitual coffee consumption and CKD in Korean women. Methods: This study involved 2,673 women aged 35 to 64 years in the Fourth Korea National Health and Nutrition Examination Surveys conducted in 2008. Habitual coffee consumption classified into three categories; less than 1 cup per day, 1 cup per day, and 2 or more cups per day. CKD was defined as estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m2 by MDRD equation. Results: Compared with drinking less than 1 cup of coffee per day, the odds ratio (OR) for CKD was 0.586 (confidence interval [CI], 0.367 0.937; P = 0.026) of habitual drinking 2 or more cups per day after adjusting for multiple