List of oral abstracts

Orals ListPan. Disc. & Symp. Abs.Keynote Abs.Keynote Bios.ProgramIAOOWelcomeCommittee Listings

Oral Oncology Supplement 3 (2009) 24–35

Contents lists available at ScienceDirect

Oral Oncology Supplement journal homepage: www.elsevier.com/locate/oraloncology

List of oral abstracts Abstracts are listed with abstract number, title, presenting author, and page number for full abstract. [O1]

Microsurgical orofacial zone reconstruction in oncologic patients.

56

[O2]

I.V. Reshetova,*, S.A. Kravtzova, A.P. Polyakova, O.V. Matorina, M.V. Ratushnyya, M.M. Phylusyina, aMoscow P.A. Hertzen Cancer Research Institute, Russian Federation Stereolithographic biomodelling in mandibular reconstruction

56

a

[O3]

[O4]

a,c

[O6]

[O8]

a

a

a

a

a

a

a

a

a

a

a

57

a

57

a

S. Bhatia *, C.V. Thomas , S. Mustafa , P. O’keef , M.J. Fardy , University Hospital of Wales and University Dental Hospital, United Kingdom Contrast enhanced harmonic imaging in free flap monitoring

57

R. Ananda,*, S. Sharmaa, S. Waljia, M. Hickmana, V. Ilankovana, K. Greavesa, aPoole Hospital NHS Trust, United Kingdom Free Flap Arterial and Venous Anastomosis Monitoring in Post-Operative Head and Neck Reconstruction of Oral Cavity Defects

58

a,

[O7]

a

R.S. Gil *, A.M. Roig , C.A. Obispo , I.J. Escalona , A.F. Fuertes , A. M. Dieguez , Oral and Maxillofacial Department Hospital Universitario de Bellvitge, Spain,bUniversidad Internacional de Cataluña. UIC, Spain,cHead and Neck Functional Unit. Bellvitge Universitary Hospital, Spain Internal Mammary Vessels For Reconstruction In Vessel Depleted Necks a,

[O5]

a,

H. Seikaly , J. Zhu , R. Chowdhury *, D. Cote , K. Ansari , J. Harris , University of Alberta, Canada Surgical Planning with Stereolithography for Mandibular Reconstruction. Our Recent Experience and Results. a,b,

a

a

a

D.W.J. Cote *, J.R. Harris , H. Seikaly , University of Alberta, Canada The Clinical Utility of Colour Flow Doppler in Planning Anterolateral Thigh Flap Harvest

58

R.S. Patela,b,*, K.M. Higginsa, D.J. Enepekidesa, P.A. Hamiltona, aSunnybrook Health Sciences Centre/Odette Cancer Centre, and University of Toronto, Canada,bAuckland City Hospital, and University of Auckland, New Zealand Reconstruction of large volume maxillo-mandibular labial defects: Maximizing oral competence, speech and swallowing

58

a,b,

a

a

a

a,c

a

K.M. Malloy *, J.S. Moyer , J.W. Zumsteg , E.J.P. Chanowski , S.S. Khariwala , D.B. Chepeha , University of Michigan, United States bUniversity of Pennsylvania Health Systems, United States, c University of Minnesota, United States Two patterns of facial artery-submental artery flaps for reconstructing defects of soft tissue and hard tissue in the oral and maxillofacial regions

59

[O10]

W.-I. Chena,*, J.-S. Lia, Z.-H. Yanga, Z.-Q. Huanga, J.-G. Wanga, B. Zhanga, aDepartment of Oral and Maxillofacial Surgery, the Second Affiliated Hospital, Sun Yat-sen University, Guangzhou 510120, China Reconstruction of mandible: 10 year experience with 178 consective patients

59

[O11]

R.A. Warraicha,*, N. Riaza, H. Abida, A. Ahsana, aKing Edward Medical University Lahore, Pakistan Per case payment in in-patient ENT-oncology – Six years experiences with Diagnosis related groups in Germany

59

[O12]

D. Franza,*, J. Albertyb, N. Roedera, aUniversity Hospital Muenster, DRG-Research-Group, Germany, bUniversity Hospital Muenster, ENT-Department, Germany Socio-economic status and incidence of Head and Neck cancer in Ottawa, Canada; a logistic regression analysis.

60

S. Johnsona,*, M.J. Corstena, J.T. McDonaldb, aUniversity of Ottawa, Canada, bUniversity of New Brunswick, Canada Epidemiology and Costs of Health Care Provision for Patients with Oro-pharyngeal and Salivary Cancers in the Northern Territory, Australia

60

M.E. Thomasa,b,*, C. Scottb, E. Yeboahb, J. Rajinikantha,b, aFlinders University, Australia bRoyal Darwin Hospital, Australia Clinical Implications of Continued Alcohol and Tobacco Consumption After Treatment for Mucosal Head and Neck Malignancies

60

a

[O9]

Poster Abstracts Oral Abstracts

a

[O13]

[O14]

J. Rajinikantha,b,*, M.E. Thomasa,b, aRoyal Darwin Hospital, Australia, bFlinders University, Australia

doi:10.1016/j.oos.2009.06.083

[O15]

The relationship between self-assessed oral health and depression in head and neck cancer patients

60

[O16]

K.S. Al-Khalifaa,*, S.A. Duffyb, B.A. Burtb, aKing Faisal University, Saudi Arabia, bUniversity of Michigan, United States Anxiety, Depression and Coping in Head and Neck Cancer Patients

61

[O17]

H. Elania,*, L. Edgara, P.J. Allisona, aMcGill University, Canada Which questionnaire? Assessing the Health Related Quality of Life in Patients with Head and Neck Cancer

61

[O18]

S.E. Fishera,b,*, A. Vikrama, A. Donnellya, A.C. Newshama, C. Johnstona, aUniversity of Leeds, United Kingdom, b University of Bradford, United Kingdom Malnutrition and Quality of Life in Patients Treated for Oral or Oropharyngeal Cancer

61

a,

a,b

a

a

c

a

H. Jager-Wittenaar *, P.U. Dijkstra , A. Vissink , R.P. van Oort , B.F.A.M. van der Laan , J.L.N. Roodenburg , Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, bDepartment of Rehabilitation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, cDepartment of Otorhinolaryngology, Head & Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands Longitudinal assessment of health-related quality of life (HRQOL) in patients with squamous cell carcinoma of the Head and Neck (HNSCC) a

[O19]

a,

a,b

a

62

b

[O20]

S.K. Haerle *, S.J. Stoeckli , University Hospital Zurich, Switzerland, Kantonsspital St. Gallen, Switzerland, University Hospital Basel, Switzerland, dPrivatklinik Bethanien, Switzerland, e University Hospital Lausanne, Switzerland, fKantonsspital Aarau, Switzerland, gUniversity Hospital Berne, Switzerland Evaluation of speech outcomes in oral and oropharyngeal cancers

62

[O21]

R. Dwivedia, J. Roea, R. Kazia, C. Nuttinga, P. Clarkea, P. Rhys-Evansa,*, aHead-Neck Unit, The Royal Marsden Hospital, London, United Kingdom Radical Radiotherapy for Early Glottic Cancer: 26 Years Experience from a Single Institution

63

[O22]

S. Ghosh Laskara,*, J.P. Agarwala, C. Srinivasa, K.A. Dinshawa, aTata Memorial Hospital, India Swallowing outcomes following Intensity-Modulated Radiation Therapy (IMRT) in head and neck cancer

63

[O23]

J.W.G. Roea, R.C. Dwivedia, R. Kazia, P.N. Cardingc, P.H. Rhys-Evansa,*, K.J. Harringtona,b, aThe Royal Marsden NHS Foundation Trust, United Kingdom, bThe Institute of Cancer Research, United Kingdom, c Newcastle upon Tyne Hospitals NHS Foundation Trust, United Kingdom Outcome in oropharynx and oral cavity tumors following IMRT

63

c

a,

b

c

a

a

G. Studer *, K.W. Graetz , G. Huber , C. Glanzmann , Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland, bDepartment of Craniomaxillofacial Surgery, University Hospital Zurich, Zurich, Switzerland, c Clinic of Otorhinolaryngology-Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland A Pilot Study To Evaluate Swallowing And Dysphagia After Radiation In Head And Neck Cancer Patients, Using MRI. Preliminary Results.

64

F. Hoebersa,*, A. Kirilovab, W. Foltzb, S. Breenb, A. Hopea, C. Menarda, aRadiation Medicine Program, Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, University of Toronto, Canada, bRadiation Physics, Department of Radiation Oncology, Princess Margaret Hospital, University Health Network, University of Toronto, Canada, cDepartment of Medical Imaging, Princess Margaret Hospital, University Health Network, University of Toronto, Canada, dDepartment of Speech Language Pathology, University of Toronto, Canada Results of a Prospective PET-guided Management of the Neck Study in Node Positive Head and Neck Squamous Cell Carcinoma (HNSCC) Following Curative Radiotherapy With or Without Concurrent Chemotherapy

64

[O26]

S.V. Porceddua,b,*, D.I. Pryora, J. Doughtona, E. Burmeistera, B.H. Burmeistera,b, M.G. Poulsena,b, a Princess Alexandra Hospital, Woolloongabba, Brisbane, Queensland, Australia, bUniversity of Queensland, Australia Floor of Mouth Carcinoma

64

[O27]

R.I. Smeea,*, J.R. Williamsa, K. Broadleya, K. Dowlinga, G.P. Bridgerb, aDepartment of Radiation Oncology, Prince of Wales Cancer Centre, Australia, bDepartment of Otolaryngology, Prince of Wales Cancer Centre, Australia The Role of Induction Chemotherapy on Survival of Locally Advanced Oral Cavity Cancer

65

K.H. Kima,*, I.J. Choia, S.Y. Ana, J.H. Haha, T.K. Kwona, M.W. Sunga, aDepartment of Otorhinolaryngology, Seoul National University College of Medicine, Republic of Korea Randomized phase II study of concomitant chemoradiation using weekly Carboplatin/Paclitaxel/concomitant boost radiation with or without daily subcutaneous amifostine in patients with newly diagnosed locally advanced head and neck cancer.

65

R. Haddada,b,*, P. Braschaykoa, S. Sonisa,b, M. Posnera,b, L. Wirtha, R. Tishlerb,a, aDana Farber cancer Institute, United States, bBrigham and Women’s Hospital, United States Outcome and toxicity of hypofractionated radiotherapy in patients with head and neck cancers who are not suitable for curative treatment: ‘‘Christie scheme”

65

R.J. Baatenburg de Jonga,*, A. Al-Mamgania, L. Tansa, P.H.E. van Rooya, I. Noevera, P. Levendaga, a ErasmusMC, Netherlands The health utilities index: an evaluation of concurrent chemoradiation and surgery with post-operative radiation

66

[O24]

[O25]

[O28]

[O29]

[O30]

E.J.P. Chanowskia,*, D.B. Chepehab, J.S.J. Leeb, F.P. Wordenb, A. Eisbruchb, G.T. Wolfb, aUniversity of Michigan Medical School, United States, bUniversity of Michigan Health System, United States

Orals ListPan. Disc. & Symp. Abs.Keynote Abs.Keynote Bios.ProgramIAOOWelcomeCommittee Listings

25

Poster Abstracts Oral Abstracts

List of oral abstracts / Oral Oncology Supplement 3 (2009) 24–35

Orals ListPan. Disc. & Symp. Abs.Keynote Abs.Keynote Bios.ProgramIAOOWelcomeCommittee Listings

26

[O31]

Penetration of polymersome drug and gene delivery nanoparticles into in vitro models of head and neck cancer and tissue engineered oral mucosa.

66

[O32]

V. Hearndena,*, G. Battagliaa, S. MacNeila, C. Murdocha, M. Thornhilla, aUniversity of Sheffield, United Kingdom Evaluation of the surgeon-dentists’ knowledge about oral cancer in Barretos Region - Brazil

66

[O33]

A.L.R.O. Avia, H.M. Tanimotoa, T.M.N. Moraisa, A.L. Carvalhoa,*, aBarretos Cancer Hospital, Brazil MicroRNA alterations in oral and pharyngeal squamous cell carcinoma

67

a,

a

a

a

a

a

a

C.B. Lajer *, M. Rossing , L. Friis-Hansen , F.C. Nielsen , L. Specht , C. Buchwald , Rigshospitalet, University of Copenhagen, Denmark, Denmark Characterization of oral tumors by massively parallel ligation sequencing to ascertain the presence of persistent antigen

67

[O35]

R.R. Labordea,*, J.L. Kasperbauera, E.J. Moorea, K.D. Olsena, N.M. Tombersa, D.I. Smitha, aMayo Clinic, United States Human oral tumors and expression of Argininosuccinate Synthetase (ASS) and Argininosuccinate Lyase (ASL)

67

[O36]

R. Aparajitaa, K. Elsetha, B.J. Vespera, K. Haines IIIb, G. Tarjanc, A. Kolokythasd,*, aCentre for Molecular Biology of Oral Diseases, College of Dentistry University of Illinois at Chicago, Illinois, United States, bDepartment of Pathology, Yale University School of Medicine, New Haven, CT, United States, cDepartment of Pathology, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL, United States, dDepartment of Oral and Maxillofacial Surgery, College of Dentistry, University of Illinois at Chicago, IL, United States Proteomics based Diagnostic and Prognostic Biomarkers for Head-and-Neck Cancer: Challenges and Opportunities

68

R. Ralhana,c,*, L.V. DeSouzaa,c, A. Mattaa,c, S.C. Tripathid, S.D. Guptae, N.K. Shuklaf, aDepartment of Chemistry, York University, Canada bDepartment of Biology, York University, Canada, cCentre for Research in Mass Spectrometry, York University, Canada dDepartment of Biochemistry, All India Institute of Medical Sciences, India, e Department of Pathology,All India Institute of Medical Sciences, India, fDepartment of Surgery, Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, India, gGynecological Pathology Section, Mount Sinai Hospital, Toronto, Ontario, Canada, iPathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada, jOral Medicine and Oral Pathology, Mount Sinai Hospital, Toronto, Ontario, Canada Hypoxia-induced secretion of CXCL12 by head and neck tumour spheroids mediates infiltration of monocytes by a CXCR4-dependent mechanism

68

[O34]

[O37]

a,

[O38]

[O39]

[O40]

[O41]

Poster Abstracts Oral Abstracts

List of oral abstracts / Oral Oncology Supplement 3 (2009) 24–35

[O42]

[O43]

a

a

a

a

C. Murdoch *, H. Colley , S. MacNeil , M. Thornhill , University of Sheffield, United Kingdom Proteomic analysis of laser-captured paraffin embedded tissues: A molecular portrait of head and neck cancer progression

68

V. Patela,*, B.L. Hoodb, A.A. Molinoloa, N.L. Leec, T.D. Veenstraf, J.S. Gutkinda, aNIDCR, United States, bUniversity of Pittsburgh Cancer Institute, United States, cGeorge Washington University Medical Center, United States, dJ. Craig Venter Institute, United States, eExpression Pathology Incorporated, United States, fNCI, United States Tumor Progression in the Oral Cavity: The Significance of Genetic Polymorphisms in CYP1A1, GST M1 and XRCC1 in a South Indian Population

69

K. Ramadasa,*, S. Ramachandranb, R. Muwongec, M.R. Pillaib, aRegional Cancer Centre, India, bRajiv Gandhi Centre for Biotechnology, India, cInternational Association for Research on Cancer, French Southern Territories Evaluation of immunohistochemical and biomolecular parameters as markers of the biological behaviour of head and neck carcinomas: preliminary results of a multicenter Italian Project.

69

T. Polia,*, A. Balestreria, R. Cocchic, C. Marchettib, M.P. Foschinib, R. Perrisb, aUniversity of Parma, Italy, bUniversity of Bologna, Italy, cBellaria Hospital- Bologna, Italy Can SLUG, SNAI1, TWIST1,TGFß, N-cadherin and E-cadherin predict the metastatic potential of oral squamous cell carcinoma?

70

E. Barkera,b, P. Reisb,*, M. Sukhaib, R. Goswamib, J. Irisha, S. Kamel-Reidb, aPrincess Margaret Hospital, Toronto, Canada, bThe Ontario Cancer Institute, The University of Toronto, Canada Mcl-1 Expression is Associated with Pathogenesis and Radiotherapy Treatment Response in Chewing Tobacco–Associated Oral Carcinomas

70

T.R. Tenia,*, S. Mallicka, V. Palvea, S. Pawara, R. Patilc, J.P. Agarwalb, aAdvanced Centre for Treatment, Research and Education in Cancer (ACTREC) Kharghar, Navi Mumbai-410210, India, bTata Memorial Hospital, Tata Memorial Centre, Parel, Mumbai 4000 12, India, cSharad Pawar Dental College, Wardha, India Induction of apoptosis in laryngeal cancer cells by a compound isolated from Pteris semipinnata L

70

a,

a

a

a

a

a

a

[O44]

G.G. Chen *, C.S. LO , H.C. Liu , A.C. Vlantis , M.C.T. Tone , C.A. van Hasselt , The Chinese University of Hong Kong, Hong Kong MAGE-A antigens in oral squamous cell carcinoma

71

[O45]

U.D.A. Müller-Richtera,*, T. Reuthera, S. Rautheb, S. Gattenlöhnerb, A.C. Küblera, aDpt. of Oral and Maxillofacial Plastic Surgery, Universityhospital Würzburg, Germany, bInstitute of Pathology, Universityhospital Würzburg, Germany Biomarkers of recurrence in oral carcinoma

71

a,

a,b

a

a

c

d

a

P. Reis *, M. Tomenson , N. Cervigne , M. Sukhai , N. Naranjo Galloni , L. Waldron , Ontario Cancer Institute, University Health Network, Canada, bUniversity of Toronto, Canada, cCalderon Guardia Hospital, Costa Rica, dUniversity Health Network, Canada, eToronto General Hospital, Canada fPrincess Margaret Hospital, Canada, gPrincess Margaret Hospital, Canada

Reversal of resistance to standard therapy in oral squamous cell carcinoma cells by RNA interference.

72

S.M. Gollina,b,*, M. Sankunnya,b, R.E. Flores-Obandoa, X. Huanga,b, R.A. Parikha,b, aUniversity of Pittsburgh Graduate School of Public Health, United States, bUniversity of Pittsburgh Cancer Institute, United States The epithelial-mesenchymal transition inducer, Snail, inhibits terminal differentiation and promotes inflammation and invasion in squamous cell carcinomas

72

J.G. Lyonsa,b,*, N. Rouea,b, V. Patelc, J.S. Gutkindc, G.M. Hallidayb, aSydney Head & Neck Cancer Institute, Australia, b University of Sydney, Australia, cNational Institute of Dental and Craniofacial Research, United States Tumour Stem Cells in Head and Neck Squamous Cell Carcinoma (HNSCC)

72

S.J. Goldiea,c*, F.M. Watta,c, R. Priceb, aCambridge Research Institute, United Kingdom, bDepartment of Plastic Surgery, Addenbrooke’s Hospital, United Kingdom, cDepartment of Genetics, University of Cambridge, United Kingdom Down-regulation of SERPINB13 Expression in Head and Neck Squamous Cell Carcinomas Associates with Poor Clinical Outcome

73

F.K.J. Leusinka,*, R. Koolea, J.A. Kummera, aUMCU, Netherlands, bNational Health Research Institutes, Taiwan, c Centre for Biostatistics, Netherlands, dUniversity Hospital Maastricht, Netherlands Comparative CDH1 (E-cadherin) analysis by gene expression and epigenetic inactivation in patients affected by oral squamous cell carcinoma (OSCC). Preliminary report.

73

[O51]

G. Pannonea,*, A. Santoroa, S. Tortorellaa, P. Bufoa, L. Lo Muzioa, S.M. Papagerakisc, aUniversity of Foggia, Italy, b University of Naples, Italy cUniversity of Michigan, United States Squamous Cell Carcinoma of Oropharynx: Influence of Site of Primary Tumour

73

[O52]

K.A. Pathaka,b,*, H. Al Hajjaja,b, N.V. Vialleta,b, D.S. Sutherlanda,b, P.D. Kerra,b, R.W. Nasona,b, aCancer Care Manitoba, Canada, bUniversity of Manitoba, Canada Squamous Cell Carcinoma of the Buccal mucosa: The Prognostic Importance of Site

74

[O53]

F. Bekiroglua,*, R.J. Shawa, D. Lowea, S.N. Rogersa, aUniversity Hospital Aintree, Liverpool, United Kingdom Squamous cell carcinoma of the floor of mouth: Outcomes and prognostic indicators

74

[O54]

J. Leaa,b,*, D. Goldsteina,b, M. Yehudaa,b, R. Moukarbela,b, R. Gilberta,b, D. Browna,b, aPrincess Margaret Hospital, Canada, bUniversity of Toronto, Canada Survival and Patterns of Relapse in Patients with Oral Tongue Cancer

74

[O55]

K. Rusthovena, D. Rabena, J. Songa, M. Kanea, T. Altoosa, C. Chena,*, aUniversity of Colorado Denver, United States Outcomes in patients with tongue cancer treated at the Princess Margaret from 1994 to 2004

74

D. Goldsteina,b,*, G. Bachara,b, J. Leaa,b, J. Whitea,b, R.W. Gilberta,b, D.H. Browna,b, aPrincess Margaret Hospital, Canada, b University of Toronto, Canada Tumor-host histopathologic variables of stromal myofibroblasts and risk score are significantly associated with recurrent disease in tongue cancer

74

A. Dobriyana,b,*, M.V.a,b, Y.P. Talmia,b, L. Bedrina,b, S. Teichera,b, R. Yahaloma,b, aSheba Medical Center, Israel, bTel Aviv University, Israel Carcinoma tongue in young adults – a retrospective review of treatment and outome in 144 patients

75

[O47]

[O48]

[O49]

[O50]

[O56]

[O57]

a,

b

a

b

a

a a

[O58]

P. Sebastian *, R. Muwonge , N.A. George , R. Sankaranarayanan1 , D. Raj , P.G. Balagopal , Regional Cancer Centre, Trivandrum, India, bInternational Agency for Research on Cancer, Lyon, France Quality assurance measures in patients treated for early oral tongue cancer

75

[O59]

A.C. Hessela, M.A. Morenoa,*, E.Y. Hannaa, A. El-Naggara, J. Lewina, R.S. Webera, aThe University of Texas M.D. Anderson Cancer Center, United States Clinical outcomes for T1-2 N0 oral tongue carcinoma treated with surgery without adjuvant radiation therapy

75

a,

b

a a

b

[O60]

A.W. Jensen *, D. Kademani , R.L. Foote , Mayo Clinic College of Medicine, Rochester, MN, United States, University of Minnesota Medical Center and Masonic Cancer Center, Minneapolis, MN, United States Cancer of the Tongue: Comparing Outcome in Patients with No Known Risk Factors to Those with High Risk Factors

76

[O61]

R. Hoda,*, J. Irishb, D. Goldsteinb, D. Brownb, G. Bachara, T. Shpitzera, aDepartment Of Otolaryngology-Head and Neck Surgery, Rabin Medical Centre, Israel, bDepartment Of Otolaryngology-Head and Neck Surgery, Toronto University, Canada Associated factors to predict wound infection after surgery in primary oral cavity cancer patients

76

[O62]

S.A. Liua,*, Y.K. Wonga, C.K. Poona, C.C. Wanga, C.P. Wanga, K.C. Tungb, aTaichung Veterans General Hospital, Taiwan, b National Chung Hsing University, Taiwan Delayed diagnosis in oral carcinoma.

76

E. Bardellinia, S. Bonadeoa, F. Amadoria,*, A. Majoranaa, aSchool of Dentistry – University of Brescia, Italy Investigation of Differences of Oral and Oropharyngeal Squamous Cell Carcinoma Among Caucasian, African American and Latino Patients

77

[O63]

a,

[O64]

a

a

a

A. Kolokythas *, T. Schlieve , M. Miloro , University of Illinois at Chicago, United States Racial Difference in the Diagnosis, Treatment and Survival of Oral Cavity Cancer Patients K.L. Yena,*, J.C. Probstb, J.R. Hebertb, T.A. Dayc, S.G. Reedc, aTzuchi University, Taiwan, bUniversity of South Carolina, United States, cMedical University of South Carolina, United States

77

Poster Abstracts Oral Abstracts

[O46]

27

Orals ListPan. Disc. & Symp. Abs.Keynote Abs.Keynote Bios.ProgramIAOOWelcomeCommittee Listings

List of oral abstracts / Oral Oncology Supplement 3 (2009) 24–35

Orals ListPan. Disc. & Symp. Abs.Keynote Abs.Keynote Bios.ProgramIAOOWelcomeCommittee Listings

28

[O65]

List of oral abstracts / Oral Oncology Supplement 3 (2009) 24–35

Modeling survival outcome of primary HNSCC in an ethnically diverse primary care cohort

77

M. Worshama,*, J. Stephena, M. Lua, A. Kapkea, M. Benningerb, aHenry Ford Health System, United States, bCleveland Clinic, United States Profile of Young Patients with Oral Squamous Cell Carcinoma (OSCC) Diagnosed at National Cancer Institute (INCA-RJ) from 2001 to 2004

78

[O67]

R.C.R. Lindenblatta, G.L. Martinezb, N.H.S. Canedoc, P.S. Fariab, F.L. Diasb, S.Q.C. Lourençoa,*, aFluminense Federal University, Brazil, bNational Cancer Institute, Brazil, cRio de Janeiro Federal University, Brazil Case control study on prognostic factor in oral squamous cell carcinoma in young patients

78

[O68]

E. Kaminagakuraa, J.G. Vartaniana, S.D. Silvaa, L.P. Kowalskia,*, aAC Camargo Hospital, Brazil Oral Cancer Control in Elderly

79

[O66]

[O69]

A. Raczkowska-Siostrzoneka,*, R. Koszowskia, I. Urbanb, aChair and Department of Oral Surgery in Bytom, Medical University of Silesia in Katowice, Poland, bStudent Research Society at the Chair and Department of Oral Surgery Bytom, Medical University of Silesia in Katowice, Poland Heterogeneity in Stage of Presentation and Survival from Oral Cavity and Oropharynx Cancers Among Asian American Sub Populations a,

c

c

a

79

b

A.U. Nguyen *, S Koo , P.L. Nguyen , B.M. Alexander , Harvard Extension School, United States, Brigham and Women’s Hospital Infectious Disease, United States, cHarvard Radiation Oncology Program, United States Measuring immuno-histochemical expression of proteins using virtual microscopy: a novel objective assessment method

79

[O71]

S.H. Al-Amada,b,*, M.J. McCulloughb, C.M. Angelc, aCollege of Dentistry, University of Sharjah, United Arab Emirates, b School of Dental Science, University of Melbourne, Australia, cGribbles Pathology, Australia Depth-sensitive optical spectroscopy for diagnosis of oral neoplasia

80

[O72]

R.A. Schwarza,*, W. Gaoa, C.R. Webera, C. Kurachib, R. Richards-Kortuma, A.M. Gillenwaterc, aRice University, United States bUniversity of Sao Paulo, Brazil, cUniversity of Texas M.D. Anderson Cancer Center, United States Autofluorescence imaging and biomarkers combined provide a predictive strategy in oral cavity malignancy.

80

[O73]

E. Barkera,b, P. Reis*b, G. Netchevb, R. Goswamib, B. Wilsonb, J. Irisha, aPrincess Margaret Hospital, Toronto, Canada, b The Ontario Cancer Institute, The University of Toronto, Canada Autofluorescence imaging for early detection of oral neoplasia

80

[O70]

a,

b

c

a

b

a

[O74]

A.M. Gillenwater *, D. Roblyer , C. Kurachi , V. Stepanek , R. Richards-Kortum , University of Texas M.D.Anderson Cancer Center, United States, bRice University, United States, cUniversity of São Paulo, Brazil Oculodynamic MRI as a valuable add-on in cranio-maxillofacial tumor staging

81

[O75]

B.-I. Berga,*, C. Koberb, C. Buitrago Telleza, E.W. Radue Palmowskia, K. Zimmerer Schwenzera, C. Scheffler Kunza, a University Hospital Basel, Switzerland, bHAW Hamburg, Germany Depth-Sensitive Optical Spectroscopy for Diagnosis of Oral Neoplasia

81

a,

[O76]

a

b

A. Gillenwater *, UTMD Anderson Cancer Center, United States, Rice University, United States Autofluorescense Imaging for Early Detection of Oral Neoplasia a,

[O77]

[O78] [O79]

[O80]

[O81]

b

b

a

a

a

a

a

a

a

a

81

a

A. Gillenwater *, D. Roblyer , M.S. Rahman , C. Kurachi , V. Stepanek , M. Williams , UTMD Anderson Cancer Center, United States, bRice University, United States Magnifying endoscopy combined with Flexible Spectral Imaging Color Enhancement (FICE) for early carcinoma of the head and neck a,

Poster Abstracts Oral Abstracts

b

82

a

K. Kawada *, T. Kawano , K. Nagai , T. Nishikage , Y. Nakajima , T. Suzuki , Tokyo Medical and Dental University, Japan Parameters defining the potential applicability of Raman spectroscopy as a diagnostic tool for oral disease

82

K. Guzea,*, M. Shortb, S. Sonisb, N. Karimbuxb, J. Chanb, H. Zengb, aHarvard, United States, bUBC, Canada Narrow band imaging (NBI) and high definition television (HDTV) in oral and oropharyngeal squamous cell carcinoma (SCC)

82

A. Majoranaa,*, A.B. Villaretb, C. Piazzab, C. Andrinia, G. Contia, P. Nicolaib, aUniversity of Brescia – Dental Clinic, Italy, b University of Brescia – ORL Clinic, Italy Multimodal visualization of craniofacial, skull base infiltrating tumors

83

C. Kobera, B.-I. Bergb,*, P. Juergensb, H.-F. Zeilhoferb, S. Zimmererb, K. Zimmerer-Schwenzerb, a HAW Hamburg, Germany, bUniversity Hospital Basel, Switzerland Site by site percentage and topographical pattern of lymph-node metastases in 174 neck dissection from 230 oral cancer patients.

83

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b

b

b

c

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G. Pannone *, R. Serpico , M. Contaldo , F. Longo , F. Ionna , S.M. Papagerakis , University of Foggia, Italy, University of Naples, Italy, cUniversity of Michigan, United States Correlates and Patterns of Nodal Disease in Head and Neck Cancer. Do they Validate the Tenets of Head And Neck Surgery? b

[O82]

a,

b

a

a

a

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C. Liew *, G. Robertson , J. Devine , C. Wales , J. Morrison , J. McMahon , West of Scotland Regional Maxillofacial Service, United Kingdom, bBeatson Oncology Centre, Glasgow, United Kingdom

83

[O84]

[O85]

[O86]

Validation of an Expression Profile for Prediction of Lymph Node Metastasis from Primary Head and Neck Squamous Cell Carcinomas (HNSCC)

84

F.K.J. Leusinka,*, P. Roepmana,b, J.A. Kummera, R. Koolea, aUMCU, Netherlands, bAgendia, Netherlands, cUMC St Radboud, Netherlands Outcome of ultrasound guided fine needle aspiration cytology for initial staging and observing the N0 neck in patients with early oral cancer

84

R. de Breea,*, G.B. Flacha, M. Tenhagena, D.J. Kuika, J.A. Castelijnsa, C.R. Leemansa, aVU University Medical Center, Netherlands The role of CT, MR, US, and 18F-FDG PET/CT in detection of upper cervical lymph node metastases in oral cavity squamous cell carcinoma

84

H.R. Chua,*, J.H. Kima, S.J. Oha, H.Y. Ahna, D.Y. Yoona, Y.S. Rhoa, aIlsong Memorial Institute of Head and Neck Cancer, Hallym University Medical Center, Republic of Korea A Preoperative Measure Of Tumor Thickness As A Predictor Of Cervical Nodal Metastasis In Oral Carcinoma

85

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[O87]

[O88]

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C. Drover , J.R.B. Trites , R. MacEachern , M. Bullock , J. Caines , S.M. Taylor *, Dalhousie University, Canada New Imaging Modalities for Sentinel Node Localization in Oral Cancer: SPECT/CT and Intra-operative Radioguidance with a Portable Gamma Camera.

85

W.M.C. Klopa,*, L. Vermeerena, R.A.V. Olmosa, A.J.M. Balma, M.W.M. van den Brekela, aNetherlands Cancer Institute/ Antoni van Leeuwenhoek Hospital, Netherlands Implementation of Sentinel Node Biopsy in the treatment of oral cavity squamous cell carcinomas – initial experience.

85

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L. Sebbesen *, A. Bilde , MH. Therkildsen , J. Mortensen , L. Specht , C. Buchwald , Dept. of ORL-H&N surgery; Copenhagen University Hospital, Denmark, bDept. of Pathology; Copnhagen University Hospital, Denmark, c Dept. of Clinical physiology & Nuclear Medicine; Copenhagen University Hospital, Denmark, dDept. of Oncology; Copenhagen University Hospital, Denmark Evaluation of the diagnostic accuracy of RT-PCR quantification of the best mRNA markers in the detection of sentinel lymph node invasion in oral and oropharyngeal squamous cell carcinoma.

86

[O90]

V. Burciaa, J. Solassolb, V. Costesc, E. Barbotted, D. Deverbiziere, R. Garrela,*, aHead and Neck Surgery, Montpellier Teaching Hospital, France, bMolecular and Cellular Biology Department, Montpellier Teaching Hospital, France, c Pathology Department, Montpellier Teaching Hospital, France, dMedical Statistics Department, Montpellier Teaching Hospital, France, eNuclear Medicine Department, Montpellier Teaching Hospital, France, fDepartment of Otolaryngology, Ninewells Hospital and Medical School, Dundee, United Kingdom What type of neck dissection should be performed after a positive sentinel node biopsy?

86

[O91]

A. Misraa,*, T. Shoaiba, L. Alkureishia, G. Rossa, T. Atulaa, D. Soutara, aCanniesburn Plastic Surgery Unit, United Kingdom Scope and limitations of different mandibular reconstruction methods – a long term follow-up

86

[O92]

P. Maurera,*, M.S. Kriwalskya, A. Wyslucha, M. Kunkela, aDepartment of Oral and Maxillofacial Surgery, Ruhr-University, Germany Osseocutaneous transplantation for mandibular osteoradionecrosis

87

[O89]

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[O93]

S.P. Chandarana *, E.J.P. Chanowski , K.A. Casper , J.S. Moyer , J. Lee , D.B. Chepeha , University of Michigan Health System, United States Maxillofacial Reconstruction with the Free Fibular Flap: 13-year Experience in a Regional Hospital in Hong Kong

87

[O94]

J.Y.W. Maka,*, W.Y. Cheunga, aKwong Wah Hospital, Hong Kong Reconstruction of mandibular defects - A clinical review over a 25-year period

87

A. Eckardta,*, B. Sinikovica, H. Kokemüllera, S. Friedrichsa, N.-C. Gellricha, aDept. of Oral and Maxillofacial Surgery, Hannover Medical School, Germany Do Osteotomies of the Free Fibula Flap in Segmental Mandibular Reconstruction Influence Complications and Outcome?

88

[O96]

J.T.M. van Gemerta,*, E.M. Van Canna, R. Koolea, aUniversity Medical Center Utrecht, Netherlands Rehabilitation after mandibular reconstruction with fibula free flap: Clinical (outcome) and quality of life assessment

88

[O97]

A.G. Dumansa,*, S.O.P. Hofera,b, A.C. Hundepoola, N. Fokkensa, S.S. Rayatta, E.H. van der Meija, aErasmus University Medical Center, Netherlands bUniversity Health Network, Canada Composite fibular free flap donor site morbidity: The Birmingham experience

88

[O98]

S.M. Halsnada,*, R. Ananda, D. Srinivasana, T. Martina, S. Parmara, aDept of oral & maxillofacial surgery, Queen Elizabeth Hospital, Birmingham, United Kingdom The scapula flap – A 15 year experience

89

[O95]

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[O99]

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F. Bekiroglu *, A.M.S. Brown , University Hospital Birmingham NHS Foundation Trust, Birmingham, United Kingdom Latissimus dorsi osseocutaneous revascularized tissue transfer: A bone flap with a long pedicle and flexible soft tissue

S.S. Khariwalaa,b,*, E.J.P. Chanowskia, J.W. Zumstega, K.M. Malloya,c, J.S. Moyera, D.B. Chepehaa, aUniversity of Michigan, United States, bUniversity of Minnesota, United States cUniversity of Pennsylvania Health Systems, United States [O100] The Scapular Tip: A new angle to mandibular reconstruction a,

b

a

b

J. Yoo *, R. Gilbert , University of Western Ontario, Canada, University of Toronto, Canada

89

89

Orals ListPan. Disc. & Symp. Abs.Keynote Abs.Keynote Bios.ProgramIAOOWelcomeCommittee Listings

[O83]

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Orals ListPan. Disc. & Symp. Abs.Keynote Abs.Keynote Bios.ProgramIAOOWelcomeCommittee Listings

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List of oral abstracts / Oral Oncology Supplement 3 (2009) 24–35

[O101] c-Met/HGF expression as a marker of tumor progression in oral tongue squamous cell carcinoma

90

Y.C. Lima,*, C.-H. Kimb, B. S. Kooc, Y.-H. Yoonc, E.C. Choid, aDepartment of Otorhinolaryngology-Head and Neck Surgery, Konkuk University School of Medicine, Republic of Korea, bDepartement of Otolaryngology, Ajou University College of Medicine, Republic of Korea, cDepartment of Otolaryngology, Head and Neck Surgery, Chungnam National University Hospital, Republic of Korea, dDepartment of Otorhinolaryngology, Yonsei Head and Neck Cancer Clinic, Yonsei University Health System, Republic of Korea [O102] Cold shock domain protein A (CSDA) inhibits lymph node metastasis via repression of lymphangiogenesis in squamous cell carcinoma

90

G. Matsumotoa,*, E. Kubotaa, aDepartment of Oral and Maxillofacial Surgery, Japan [O103] Chromosome instability predicts progression of premalignant lesions of the larynx

90

V.E. Bergshoeffa, F.J. Botb, F.C.S. Ramaekersc, J.J. Mannia, B. Kremera, E-J.M. Speelb,c,*, aDepartment of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, Netherlands, bDepartment of Pathology, Maastricht University Medical Center, Netherlands, cDepartment of Molecular Cell Biology, Maastricht University Medical Center, Netherlands [O104] Induction of xenobiotic drug metabolizing enzymes by smokeless tobacco, a culprit for oral cancer K.L. Khandujaa,*, P. Avtia, C.M. Pathaka, K. Vaipheia, aPGIMER, Chandigarh, India [O105] Functional Alteration of Oral Squamous Cell Carcinoma Aggressive Behavior Through uPAR-Associated Changes in Gene Expression

91

M. Sharon Stacka,*, J.J. Johnsona, Z. Shia, S. Fraziera, R. Jianga, aUniversity of Missouri, United States [O106] Profiling Of Metastatic and Non-Metastatic Oral Squamous Cell Carcinoma Using Array Comparative Genomic Hybridization

91

A. Bhattacharyaa,*, R.C.K. Jordana, D.G. Albertsona, B.L. Schmidta, aUniversity of California San Francisco, San Francisco CA, United States [O107] Differential expression of Glucose transporter 1 (GLUT1) and Carbonic Anhydrase IX (CA9) in human Head and Neck Squamous Cell Carcinomas

92

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c

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91

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K. Shevchenko , M. Williams , S. Narendran , N. Vigneswaran *, Department of Diagnostic Sciences, The University of Texas Dental Branch at Houston, United States, bDepartment of Pathology, The University of Texas M.D. Anderson Cancer Center, United States, cDepartment of Community Dentistry, Case Western University School of Dental Medicine, United States [O108] microRNA Over-expression Predicts Progression of Oral Leukoplakia to Same-Site Oral Carcinoma

92

N. Cervignea,b,*, P. Reisa, N. Gallonia,e, J. Machadoa,d, B. Sadikovicc, S. Kamel-Reida,c, aOntario Cancer Institute, Princess Margaret Hospital, Canada, bDepartment of Otolaryngology, Hospital Calderon Guardia, Costa Rica, cHospital for Sick Children, Canada, dFaculty of Dentistry, University of Toronto, Canada [O109] Enhanced Self-Renewal Properties of Transformed Oral Epithelial Cells after Interactions with Stromal Fibroblasts

92

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b

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D.E. Costea *, A.H. Osman , A. Ipatova , D. Sapkota , E. Neppelberg , S. Lybak , University of Bergen, Norway, bHaukeland University Hospital, Norway, cQueen Mary University of Bergen, United Kingdom [O110] Epigenetic inactivation of the WNT-pathway genes in oral squamous cell carcinoma. Preliminary report.

93

G. Pannonea,*, P. Bufoa, P. Papagerakisc, F. Sanguedolcea, A. Santoroa, L.L. Muzioa, aUniversity of Foggia, Italy, b University of Naples, Italy cUniversity of Michigan, United States [O111] Weekly Docetaxel in Patients with Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck.

93

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P. Specenier *, M. Rasschaert , Ph. Vroman , Antwerp University Hospital, Belgium, OLV Hospital Aalst, Belgium Iridium Cancer Network, Belgium [O112] A novel fusogenic herpes simplex virus mutant for oncolytic virotherapy of oral squamous cell carcinoma

93

Y. Yuraa,*, H. Takaokaa, F. Ogawaa, M. Shintania, S. Iwaia, aOsaka University, Japan [O113] Matrix metalloproteinase-7 and -13 predict response to cisplatin in head and neck cancer

94

Poster Abstracts Oral Abstracts

c

A. Ansella, F. Jerhammara, R. Cederc, R. Grenmand, K. Roberga,b,*, aDepartment of Clinical and Experimental Medicine, Division of Otorhinolaryngology, Linköping University, Sweden, bDivision of Otorhinolaryngology, University Hospital, SE-58185 Linköping, Sweden, cInstitute of Environmental Medicine, Division of Biochemical Toxicology and Experimental Cancer Research, Karolinska Institution, Stockholm, Sweden, dDepartment of Otorhinolaryngology, Head & Neck Surgery, Turku University Central Hospital, Finland [O114] Pre-clinical development of a bi-functional, cancer cell homing, PKCe inhibitory peptide for the treatment of head and neck cancer L.W. Baob, M.A. Gorinc, S.D. Merajverb, T.N. Teknosa, Q. Pana,*, aThe Ohio State University Medical Center, United States, b University of Michigan Medical School, United States, cMiller School of Medicine, University of Miami, United States [O115] Curcumin inhibits HNSCC by modulating the Akt/mTOR pathway

94

C.A. Clarka,b, Y. Ronga, X. Ronga, S. Shaha, H. Barhama, C. O. Nathana,b,*, aLSUHSC-Shreveport, United States, b Feist-Weiller Cancer Center, United States [O116] Telomerase-Specific Replication-Selective Virotherapy for oral squamous cell carcinoma cell lines

95

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c,d

b,c

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S. Shintani *, Y. Kurihara , Y. Watanabe , T. Kojima , T. Shirota , M. Hatori , Department of Oral and Maxillofacial Surgery, School of Dentistry, Showa University, Japan, bDivision of Surgical Oncology, Department of Surgery, Okayama University, Graduate School of Medicine and Dentistry, Japan, cCenter for Gene and Cell Therapy, Okayama University Hospital, Japan, dOncolys BioPharma, Inc., Japan

94

31

[O117] Oropharyngeal Cancer with Advanced-Stage Regional metastasis: Outcomes Following Primary Chemoradiation Therapy

95

R.V. Moukarbela,*, V. Venkatesana, S. Pavamania, A. Hammonda, N. Reada, J.H. Franklina, aThe University of Western Ontario, Canada [O118] FDG-and Acetate-PET in radiotherapy. Insights in tumour volume definition, oxidative metabolism and perfusion related to radio-responsiveness.

95

S.J. Johanssona,b,*, A.S. Sunc, I.T. Turessona, J.S. Sörensenb, aDep of Oncology, Uppsala University Hospital, Sweden, b Dep of Nuclear Medicin, Uppsala University Hospital, Sweden, cDep of Radiation Sciences, Umea University Hospital, Sweden [O119] Management of Oral Tongue Carcinoma

96

R.I. Smeea,*, K. Broadleya, J.R. Williamsa, aDepartment of Radiation Oncology, Prince of Wales Cancer Centre, Australia [O120] Shoulder Problems In Patients Treated By (Chemo)Radiation For Head And Neck Cancer: An Overlooked Sequel.

96

S. van Weerta,*, M. van Wouwea, R. de Breea, P. Doornaerta, D. Kuika, C.R. Leemansa, aVU University Medical Center Amsterdam, Netherlands [O121] Profiling of Epstein-Barr Virus Gene Expression Pattern in Oral Squamous Cell Carcinoma for Assessing Viral Tumorigenic Factor

96

C.Y. Yena,*, S.Y. Liua, C. Lib, aOral and Maxillofacial Surgery, Chi Mei Medical Center, Taiwan, bDepartment of Microbiology and Immunology, National Chiayi University, Taiwan [O122] Identification of Cancer Stem cells (CSC) from primary Oral Squamous Cell Carcinoma (OSCC)

96

J.H. Leea,*, K.S. Kimb, M.J. Kima, S.M. Kima, K.H. Changb, H.J. Yoonb, aDepartment of Oral & Maxillofacial Surgery, School of Dentistry, Seoul National University, Republic of Korea, bCell and Immunobiology, and R&D Center for Cancer Therapeutics, National Cancer Center, Republic of Korea [O123] Improved prognosis of p16 positive oropharyngeal cancer is independent of treatment modality.

97

C.A. Fischera,*, I. Zlobecb, L. Tornillob, A. Luglib, M. Wolfensbergera, L.M. Terraccianob, aDepartment of Otolaryngology, Head and Neck Surgery, University Hospital, Petersgraben 4, 4031 Basel, Switzerland, bInstitute of Pathology, University Hospital, Schönbeinstrasse 40, 4031 Basel, Switzerland [O124] TGF-beta1-Induced Expression of the Poor Prognosis SERPINE1/PAI-1 Gene in Oral Carcinoma Requires EGFR Signaling

97

R. Samarakoona, C.E. Higginsa, S.P. Higginsa, P.J. Higginsa,*, aAlbany Medical College, United States [O125] Hyaluronan promotes Rho kinase and PI-3 kinase signaling in head and neck cancer

97

S.J. Wanga,*, C. Torrea, W. Xiaa, L.Y.W. Bourguignona, aUniversity of California, San Franciso, United States [O126] Cooperation between cancer cell clones: a new paradigm for the malignant progression of carcinomas

98

J.G. Lyonsa,b,*, E. Lobob, M.R. Myerscoughb, aSydney Head & Neck Cancer Institute, Australia, bUniversity of Sydney, Australia [O127] EPS8 in Squamous Carcinogenesis

98

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a

b

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H. Wang , V. Patel , H. Miyazaki , J.S. Gutkind , W.A. Yeudall *, Virginia Commonwealth University, United States NIDCR, United States [O128] No mutation of p53 in the surgical margin of oral carcinomas

98

A. Bildea,*, C. Thodeb, M.H. Therkildsenc, P. Guldbergd, C. von Buchwalda, E. Dabelsteenb, aDept. of ORL – H&N Surgery, Copenhagen University Hospital, Copenhagen, Denmark, bDept. of Oral Diagnostics, Dental Institute ,University of Copenhagen, Copenhagen, Denmark, cDept. of Pathology, Copenhagen University Hospital, Copenhagen, Denmark, d Institue of Cancer Biology, Danish Cancer Society, Copenhagen, Denmark, Denmark [O129] Characterization of genomic and transcriptomic alterations in four oral tongue tumors by massively parallel ligation sequencing

99

b

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b

a

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D.I. Smith *, B. Tuchs , R. Laborde , E. Moore , J. Kaspaerbauer , S. Middha , Mayo Foundation, United States, Applied Biosystems, United States [O130] Transcriptome Signature of the Extracellular Matrix and Adhesion Molecules in Oral Squamous Cell Carcinomas from Sudanese N-nitrosamine Rich Toombak Users b

a,

a

a

a

D. Sapkota *, O. Bruland , E.N. Vasstrand , S.O. Ibrahim , University of Bergen, Norway [O131] Lapse in Oral Cancer Staging? Role of Three Dimensional CT scan in Oral Cancer Diagnosis & Staging. a,

b

b

99

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b

b

b

100

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K. Madhabananda *, T. Sanjay , Deo S.V.S , K. Sunil , D.G. Sidhartha , Shukla N. K. , Kalinga Institute of Medical Sciences, India, bAll India Institute of Medical Sciences, India [O132] Transoral Robotic Surgery for Oropharyngeal Carcinoma- Functional and Oncologic Outcomes

100

E.J. Moorea,*, K.D. Olsena, J.L. Kasperbauera, aMayo Clinic, United States [O133] Assessment of tumor thickness in oral carcinoma using an intraoral ultrasound probe

100

W.J. Loddera, H.J. Teertstraa, I.B. Tana,b, F.A. Pameijera, L.E. Smeelea, M.W.M. van den Brekela,b,*, aNetherlands Cancer Institute Amsterdam, Netherlands, bUniversity of Amterdam, Academic medical Cencter, Netherlands [O134] Anterior craniofacial resection in centro-facial tumors a

a,

b

b

a

G. Rivera , J.F. Gallegos-Hernandez *, G. Guinto-Balanzar , F. Cohn-zurita , G. Minauro-Muñoz , H. Arias-Ceballosa, aHospital de Oncología, CMN, IMSS, Mexicom, bHospital de Especialidades, CMN. IMSS, Mexico

101

Poster Abstracts Oral Abstracts

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List of oral abstracts / Oral Oncology Supplement 3 (2009) 24–35

[O135] The results of salvage treatment for regional recurrence in oral squamous cell carcinoma

101

C.S. Chenga,*, Y.L. Hsiaoa, Y.K. Wonga, aTaichung veterans general hospital, Taiwan [O136] Frozen section analysis of bony mandible for rapid assessment of malignant infiltration

101

A. Wyslucha, M. Kiwalskya, I. Strickera, F. Hoelzlea, K.-D. Wolffa, P. Maurera,*, aRuhr-Universität Bochum, Germany [O137] The Mandibulotomy: Friend or Foe? Part I: Safety Outcomes

102

P. Dziegielewskia,*, M.A. Mlynareka, D. Cotea, J. Dimitria, J. Harrisa, H. Seikalya, aUniversity of Alberta, Canada [O138] The mandibulotomy: friend or foe? Part II: aesthetic and functional outcomes

102

P. Dziegielewskia,*, D.A. O’Connella, D. Cotea, J. Riegerb, M.A. Mlynareka, H. Seikalya, aUniversity of Alberta, Canada, b Institute for Reconstructive Sciences in Medicine, Canada [O139] Factors affecting the duration of gastrostomy after maxillofacial oncology surgery.

102

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C. Avery *, University Hospitals of Leicester, United Kingdom [O141] Microinvasive access to the visceral autoflaps for microsurgical reconstruction in head and neck cancer patients a,

a

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a

103

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I.V. Reshetov *, V.I. Chissov , S.A. Kravtsov , M.V. Ratushnyy , P.A. Hertzen Moscow Cancer Research Institute, Russian Federation [O142] A proposal of the new guideline for the reconstruction of oral cavity and oropharynx

103

M.S. Kima,*, J.U. Parka, J.H. Choa, Y.H. Jooa, K.J. Choa, D.I. Suna, aThe Catholic University of Korea, Republic of Korea [O143] Perforator flaps: New standard in head and neck reconstruction

104

L.F. Pingarrón martina,*, J.M. López-arcasa, L.J. Arias Galloa, M.J. Morán Sotoa, I. Navarro Cuéllara, M. Burgueño Garcíaa, aUniversity Hospital La Paz, Spain [O144] Tongue reconstruction with free flaps

104

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P. Yadav *, Tata Memorial hospital, India [O145] Functional reconstruction of near total glossectomy defects using composite gastro omental-dynamic gracilis flaps a

a

a

a

a,

104

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S. Duarah , M. Sharma , S. Salih , M.A. Kuriakose , S. Iyer *, Amrita Institute of Medical Sciences, Kochi, India [O146] Comparative study of the anterolateral thigh flap versus the radial forearm free flap in head and neck cancer reconstruct

104

A. María,*, C. Arranza, S. Ramona, aHospital Universitari Bellvitge, Spain [O147] Reconstruction of Mid-facial Defect with Free Tissue Transfer after Surgery of Nasal Cavity and Maxillary Sinus Cancer

105

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Y.H. Joo *, D.I. Sun , J.H. Cho , K.J. Cho , S.H. Cho , M.S. Kim , The Catholic University of Korea, Republic of Korea [O148] Microvascular maxillar reconstruction: functional and cosmetic, cost outcomes. a,

a

a

a

H. Seikaly *, J. Rieger , K. Ansari , J.R. Harris , University of Alberta, Canada [O149] Iliac Crest-Tensor Facia Lata osteomyocutaneous flap for orbitomaxillary reconstruction a,

a

105

a

105

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S. Iyer *, M.A. Kuriakose , Amrita Institute of Medical Sciences, Kochi, India [O150] The Current Role of the Pedicled Pectoralis Major Flap in Reconstructive Head and Neck Surgery.

105

C.M.E. Averya,*, S.T. Cranka, J.P. Haytera, aUniversity Hospitals of Leicester, United Kingdom [O151] Evaluation of positron-emission and computed tomography (PET-CT) imaging service for patients with malignant cervical lymph nodes and an unknown primary tumour

106

M.J. Monteiroa,*, K. Altmana, J. Herolda, G. Burkilla, I. Francisa, J. Dikomitea, aBrighton and Sussex University Hospitals NHS Trust, United Kingdom [O152] Evaluation of Molecular markers for the assessment of occult metastasis in Lymph nodes in Head and Neck Squamous Cell carcinoma

106

A. Suresha, S. Duaraha, K.R. Hirana, S. Sundarama, V. Kekatpurea, M.A. Kuriakosea,*, aAmrita Institute of Medical Sciences, Kochi, India [O153] Neck dissections; factors affecting outcomes and morbidity

106

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a

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R. Walker , V. Bhatt *, N. Barnard , Worcestershire Acute Hospitals NHS Trust, United Kingdom [O154] Identification and Validation of Diagnostic/Prognostic markers for Tongue Cancer a

a

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a,b

a,

107

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A. Suresh , M. Vannan , K. Dhanya , E.M. Elango , K. Thangaraj , M.A. Kuriakose *, Amrita Institute of Medical Sciences, Kochi, India, bCentre for Cellular and Molecular Biology, hyderabad, India [O155] The presence of occult metastases in non-sentinel lymph node in oral squamous cell carcinoma

107

A.C. Christensena,*, A.B. Bildea, M.H.T. Therkildsena, B.C. Charabia, J.K. Kirkegaarda, L.S. Spechta, aDept. of ORL – H&N surgery, Dept. of Pathology, Dept. of Oncology, Copenhagen University Hospital, Denmark [O156] Nodal Metastasis in Clinical Stage I and II Tongue and Floor of the Mouth Squamous Cell Carcinomas

107

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D.R. Camisasca *, F.L. Dias , P.A.S. Faria , D.A. Pereira , G. Alves , S.Q.C. Lourenco , Pathology Post Graduation Program – Fluminense Federal University (UFF), Brazil, bApplied Genetics Laboratory - National Cancer Institute (INCA-RJ), Brazil, cHead and Neck Service (INCA-RJ), Brazil, dPathology Division (INCA-RJ), Brazil [O157] Prediction of Subclinical Regional Lymph Node Metastasis in Stage I/II Squamous Cell Carcinoma of the Tongue K. Nakamoia,*, A. Miyazakia, Y. Sogabea, T. Imaia, T. Yamamotoa, aDepartment of Oral Surgery, Sapporo Medical University School of Medicine, Japan

108

[O158] Improving the pN staging accuracy with sentinel node biopsy in T1-T2 N0 oral and oropharyngeal squamous cell carcinoma.

108

R. Garrela,*, V. Costesb, J.L. Failliec, Q. Gardinerd, C. Cartiera, M. Zancae, aHead and Neck Surgery Department, Gui de Chauliac Hospital, Montpellier University Hospital Center, France, bPathology Department, Gui de Chauliac Hospital, Montpellier University Hospital Center, France, cMedical Statistics Department, Arnaud de Villeneuve Hospital, Montpellier University Hospital Center, France, dDepartment of Otolaryngology, Ninewells Hospital and Medical School, Dundee, United Kingdom, eNuclear Medicine Department, Gui de Chauliac Hospital, Montpellier University Hospital Center, France [O159] Predictive Factors of Nodal Metastasis in Tonsil Cancer

109

D.J. Leea,*, S.J. Choa, H.R. Chua, J.H. Kima, H.Y. Ahna, Y.S. Rhoa, aIlsong Memorial Institute of Head and Neck Cancer, Hallym University Medical Center, Republic of Korea [O160] Management of Cervical Lymph Node Metastasis in Tonsillar Squamous Cell Carcinoma

109

K.J. Choa,*, Y.H. Jooa, D.I. Suna, J.H. Choa, J.U. Parka, M.S. Kima, aThe Catholic University of Korea, Republic of Korea [O161] Surgery alone versus surgery plus radiotherapy for patients with T1T2N0 oral squamous cell carcinoma

109

F. Jégouxa,*, N. Alnob, C. Bedferta, A. Cazéa, G. Le Clecha, aService d’otorhinolaryngologie et chirurgie maxillofaciale. Centre Hospitalo-Universitaire, Rennes., France, bService de pathologie et chirurgie buccale. Centre Hospitalo-Universitaire, Rennes., France [O162] Excisional biopsy with margin control for small oral squamious cell carcinoma

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S.-P. Hao *, K.-H. Fang , J. Zheng , Chang Gung Memorial Hospital, Taiwan, Chang Gung University, Taiwan, Xiamen Chang Gung Hospital, China [O163] Determining the optimal length for resection margins in treating oral SCC.

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A.C. Chenga,*, B.L. Schmidta, aUniversity of California, San Francisco, United States [O164] A prospective study of surgical margin status in oral squamous cell carcinoma ( oscc)

110

Y. Rana,b,*, M. Vereda,b, S. Teichera,b, Y.P. Talmia,b, L. Bedrina,b, A. Dobriyana,b, aSheba Medical Center, Israel, b Tel Aviv University, Israel [O165] Comparing the Performance of Quantitative Cytology versus the Oral CDX Brush TestÒ.

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A.R. Kerr *, S. Kafle , W. Peng , D.A. Sirois , New York University, United States, University of Southern California, United States [O166] Lab-on-a-chip Sensor for Analysis of Cellular Biomarkers in Oral Exfoliative Cytology: A New Diagnostic Tool for Early Detection of Oral Cancer a,

b

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S.E. Weigum *, S.W. Redding , C. Yeh , H.S. McGuff , N. Vigneswaran , J.T. McDevitt , Department of Chemistry and Biochemistry, University of Texas at Austin, United States, bDepartment of Dental Diagnostic Sciences, University of Texas Health Science Center at San Antonio, United States, cDepartment of Pathology, University of Texas Health Science Center at San Antonio, United States, dDepartment of Otolarynology Head and Neck Surgery, University of Texas Health Science Center at San Antonio, United States, eDepartment of Diagnostic Science, University of Texas Health Science Center at Houston, United States fDepartment of Pathology, M.D. Anderson Cancer Center, United States [O167] Targeting Oral Cancer lesion in vivo with modularly designed magnetite nanoparticles a,

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D.-B. Shieh *, P.-C. Wu , F.-Y. Cheng , C.-S. Yeh , Inst. Oral Medicine, National Cheng Kung University, Taiwan bDept. Chemistry, National Cheng Kung University, Taiwan [O168] Integration of clinical, histopathological, radiological and biomolecular data for prediction of oral cancer reoccurrence: the NeoMark Project’s first report

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T. Polia,*, A. Balestreria, D. Ardigòa, E. Silinia, R. Perrisa, E. Sesennaa, aUniversity of Parma, Italy [O169] A Novel Morbidity Prediction Score for Head and Neck Oncosurgeries

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M. Thomasa, N.A. Georgea,*, P. Sebastiana, P.G. Balagopala, P.S. Georgea, aRegional Cancer Centre, Trivandrum, India [O170] Predictors of recurrence in carcinoma of the lower gingiva and buccal mucosa – a review of 499 patients

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N.A. Georgea,*, P. Sebastiana, R. Sankaranarayananb, B.S. Anisha, R. Kashyapa, R. Muwongeb, aRegional Cancer Centre, Trivandrum, India, bInternational Agency for Research on Cancer, Lyon, France [O171] Nodal Ratio is an Independent Predictor of Survival in Squamous Cell Carcinoma of the Oral Cavity

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M.G. Shrimea,*, G. Bacharb, J. Leaa, C. Vollingc, C. Mad, P. Gullanea, aUniversity of Toronto Health Network, Departments of Otolaryngology and Surgical Oncology, Princess Margaret Hospital, University of Toronto, Canada, bDepartment of Otolaryngology, Rabin Medical Center, Petah Tiqwa, Israel, cUniversity of Toronto Medical School, Canada, dDepartment of Biostatistics, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada [O172] Predictive factors for occult metastases in sentinel lymph nodes of early oral squamous cell carcinomas

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M. Goerkema, M. Tinguelyb, J. Braunc, S.J. Stoecklid,*, aOtorhinolaryngology, University Hospital Zurich, Zurich, Switzerland, bPathology, University Hospital Zurich, Zurich, Switzerland, cBiostatistics, University of Zurich, Zurich, Switzerland, dOtorhinolaryngology, Kantonsspital St. Gallen, St. Gallen, Switzerland [O173] Is Prophylactic Neck Dissection Mandatory in T1/T2 N0 Oral Cancer Patients?

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I.A. El-Naaja,*, Y. Leisera, M. Shveisa, M. Peleda,b, aThe Department of Oral and Maxillofacial Surgery, Rambam Medical Center, Haifa, Israel, bThe Faculty of Medicine, Technion, Haifa, Israel

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List of oral abstracts / Oral Oncology Supplement 3 (2009) 24–35

[O174] Total Node Count in Neck Dissection – Is it significant? D. Srinivasana, R. Anandb, S. Farooqa, M. Halsnadb,*, T. Malinsa, P. Grimea, aUniversity Hospitals of Northstaffordshire, United Kingdom, bUniversity Hospitals of Birmingham, United Kingdom [O175] Metastases to Level IIb in squamous cell carcinoma of the oral cavity: A systematic review and meta-analysis J. Leaa,b,*, G. Bachara,b, A. Sawkaa,b, D.C. Lakraa,b, R.W. Gilberta,b, J.C. Irisha,b, aUniversity Health Network, Canada, b University of Toronto, Canada [O176] A Double Blind Randomized Control Trial of Selective Neck Dissections Including Level 2b or Not 2b on Electromyography, Clinical Examination and Questionnaire-Based Outcomes. S.A. Parikha,*, B. Tedmanb, B. Scotta, D. Lowea,c, S.N. Rogersa,c, aUniversity Hospital Aintree, United Kingdom, bWalton Neuroscience Centre, United Kingdom, cEdge Hill University, United Kingdom [O177] Neck Dissection in Node Positive Squamous Cell Carcinoma of Oropharynx K.A. Pathaka,b,*, H.A.L. Hajjaja,b, R.W. Nasona,b, aCancer Care Manitoba, Canada, bUniversity of Manitoba, Canada [O178] Salvage treatment for isolated nodal recurrence after curative surgery for head and neck squamous cell carcinoma a,

b

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d

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J.-Y. Lim *, Y.C. Lim , S.-H. Kim , H.J. Hong , E.C. Choi , Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine, Republic of Korea, bDepartment of Otorhinolaryngology-Head and Neck Surgery, Konkuk University College of Medicine, Republic of Korea, cDepartment of Otorhinolaryngology-Head & Neck Surgery, National Health Insurance Corporation, Ilsan Hospital, Republic of Korea, dDepartment of Otorhinolaryngology, Yonsei Head and Neck Cancer Clinic, Yonsei University Health System, Republic of Korea [O179] Cervical Metastasis of Squamous Cell Carcinoma of the Upper Jaw – a retrospective study of 9 years A.L.D. Krusea,*, K.W. Graetza, aUniversity Hospital Zurich, Department of Craniomaxillofacial and Oral Surgery, Switzerland [O180] Squamous cell carcinoma of the maxilla: is elective neck dissection indicated? F. Bekiroglua,*, R.J. Shawa, J.S. Browna, E.D. Vaughana, aUniversity Hospital Aintree, United Kingdom [O181] Cohort Studies in Oral Precancer Management : Intervention vs Observation P.J. Thomsona,*, M.L. Goodsona, O. Hamadaha, aNewcastle University, United Kingdom [O182] Pan-endoscopy of the upper aerodigestive tract for patients with oral cancer

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K.M. Rodriguez-Brunoa,*, M.J. Alia, S.J. Wanga, aUniversity of California, San Francisco, United States [O183] Efficacy of follow up after treatment of a squamous cell carcinoma of the oral cavity an oropharynx

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J.L.N. Roodenburga,*, M.C. Hamstraa, I.S. Haring van dera, G.H. Bock dea, aUniversity Hospital Groningen, Netherlands [O184] Oral & Pharyngeal Cancer (OPC) Screening in Irish Addiction Treatment Centres

117

E.M. O’Sullivana,*, aCork University Dental School & Hospital, Ireland [O185] Novel Computer-based Assessment of Frontline Defenders for Secondary Prevention of Oral Cancer

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C.M. Patela,*, D.K. Lama, B.L. Schmidta, aUniversity of California San Francisco, Department of Oral & Maxillofacial Surgery, United States [O186] Epidemiology of Oral Cancer in the West Midlands, UK

118

K. Rehmana,*, A. Monaghana, aUniversity Hospital Birmingham, United Kingdom [O187] A Population-Based Study of Case Mix, Treatment and Outcome of Oral Cavity Cancer Across the Geographic Regions of Ontario, Canada

118

P. Groomea,*, S. Rohlanda, S. Halla, J. Irishb, W. Mackillopa, B. O’Sullivanb, aDivision of Cancer Care and Epidemiology, Queen’s University Cancer Research Institute, Canada, bPrincess Margaret Hospital, Canada [O188] Controversies In The TNM Staging For Head And Neck Cancers

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R. Kazi , K. Manikantan , B. Elmiyeh , C. Nutting , P. Rhys-Evans *, K. Harrington , Royal Marsden NHS, United Kingdom [O189] Low incidence rates of oral cancer in patients using COX-2 inhibitors -an analysis from national health insurance database in Taiwan

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Y.H. Yanga,*, P.S. Hoa, C.L. Chengb, Y.C. Koa, Y.H. Kao Yangb, aKaohsiung Medical University, Taiwan, bNational Cheng Kung University, Taiwan [O191] Chromosome stability in tonsillar squamous cell carcinoma is associated with HPV and a favorable prognosis

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J.J. Mooren *, A.H.N. Hopman , F.C.S. Ramaekers , J.J. Manni , B. Kremer , E-J.M. Speel , Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, Netherlands bDepartment of Molecular Cell Biology, Maastricht University Medical Center, Netherlands [O192] Double demonstration of oncogenic HPV DNA and HPV-E7 protein in 8,57% of oral cancers. Preliminary report. G. Pannonea,*, P. Bufoa, A. Santoroa, S.M. Papagerakise, C. Rubinid, L.L. Muzioa, aUniversity of Foggia, Italy, bUniversity of Naples, Italy, cUniversity of Palermo, Italy, dUniversity of Ancona, Italy, eUniversity of Michigan, United States [O193] HPV Identification and Immunohistochemical Expression of Retinoblastoma Pathway Proteins in Oral Carcinogenesis R. Acaya,*, S.O.M. de Sousaa, aUniversity of São Paulo, Brazil [O194] HPV Detection in Head and Neck Cancer using the Roche Linear Array HPV Genotyping Test. J. Machadoa,b,*, P.P. Reisb, T. Zhangb, C. Simpsonb, W. Xub, B. Perez-Ordonezb, aUniversity of Toronto, Canada, b University Health Network, Canada [O195] The prevalence of human papillomavirus (HPV) in oral and oropharynx squamous cell carcinoma a,

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D. Polz *, M. Polz-Dacewicz , K. Morshed , Medical University Lublin, Poland, Medical University Lublin, Poland c Medical University Lublin, Poland

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[O196] Human papiloma virus in oral squamous cell carcinomas from young non-smokers in the region of Northern Greece

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A.K. Kyrgidisa,b,*, R.V. Valeria, G.K. Koloutsosa,b, A.N. Ntomouchtsisa, K.V. Vahtsevanosa, D. Mangoudib,a, a Department of Oral and Maxillofacial Surgery, Theagenio Cancer Hospital, Thessaloniki, Greece, bUniversity Department of Oral Maxillofacial Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece, cDepartment of Cytology, Theagenio Cancer Hospital, Greece [O197] The aetiopathogenesis of HPV in malignant disease: evidence for a global immunisation programme

121

M.S. Miaha,*, R.A. Crosbiea, R.E. Mountaina, S. Mahendrana, aNinewells Hospital and Medical School, Dundee, United Kingdom [O198] Etiologic significance of Human Papilloma Virus in Oropharyngeal Squamous Cell Carcinoma in relation to Tobacco and Alcohol

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F. Farshadpoura, S. Koningsa, J.S. Speelb, P. Slootwega, R. Koolea,*, J.A. Kummera, aUniversity Medical Center Utrecht, Netherlands, bUniversity Medical Center Maastricht, Netherlands [O199] Molecular Characterization of HPV16-Associated Squamous Cell Carcinomas of the Oropharynx and Larynx

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D. Holzinger , G. Halec , M. Schmitt , M. Pawlita , F.X. Bosch *, Molecular Biology Laboratory, Department of Otolaryngology, Head and Neck Surgery, Heidelberg University, Germany, bDivision of Genome Modifications and Carcinogenesis, DKFZ, Heidelberg, Germany [O200] Prognostic value of HPV and cervical metastasis in oropharyngeal squamous cell carcinomas. J.M.J.A.A. Straetmansa,*, N. Olthofa, I. Vosa, E.J.M. Speela, J. de Jongb, B. Kremera, aMaastricht University Medical Centre, Netherlands, bMaastricht Radiation Oncology Hospital, Netherlands

122

Orals ListPan. Disc. & Symp. Abs.Keynote Abs.Keynote Bios.ProgramIAOOWelcomeCommittee Listings

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Poster Abstracts Oral Abstracts

List of oral abstracts / Oral Oncology Supplement 3 (2009) 24–35