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Lung carcinoma and old tuberculous lesions: coexistence or coincidence. Analysis of operation samples
Abstracts
our department in the period 1994-1997. Altogether 64 cases (81%) were infectious, but only 17 (26%) were infections microbiologically defined, (50% gram negatives, 48% gram positives, 2% anaerobic), eight cases (10.1%) were fever of unknown origin (FUO), seven (8.9%) were fever not related to infection. In 11 cases (13.9%), febrile neutropenia was found, lasting less than 6 days, six cases (7.5%) having polymorphonuclear leukocytes less than 100/mm3. In 24% of cases is infection associated by obstruction - pneumonia. Effectiveness of antibiotic therapy in the first line treatment was 90%. According to the calculated trend curve we have to expect about 45 such new cases in 1998. Lung cancer: impact of mental conditions Semotanova M, Semotln’ J. ‘Independent - Bohnice 138, Czech Republic, and Psychiatry (Deceased).
Scientist, Prague 8 2Senior Resident in Neurology
Mental conditions, being as important in any human being as his somatic, social and spiritual personality traits, form part of prevention, therapy, and rehabilitation of lung cancer, in life regime, tumours, metastases, and following an operation. This is important especially in tobacco smoking and other dependencies, complicated with emotional and social stresses e.g. in passive smoking in the environment, at work, in the family, in a child group, etc. In the course of any therapy, a patient being aware of his cancer, an operation necessity or no more possibilities may result in dysfunction of somatic organs and a reduced resistance, depressive moods, and even suicide. Psychiatric consultation proves sometimes necessary. Mental support may improve cooperation, immunity system function, choice of an adequate, non-smoking party, finding new hobbies, and the assistance of a clergyman to find confidence in God and peace of mind. The same may be required in a rehabilitation period, and with permanent tobacco abstinence. Cardiospecific troponin T - the evaluation of its usefulness for staging the heart muscle’s injury in the course of a high-dose epirubicin chemotherapy Kozielski’ J, Bartnikowa’ W, Kaminski’ J, Deja2 R, Wygoda’ Z, Czernik2 E, Wydmarski2 J, Koterbicka2 A. ‘Clinic of Phthisiopneumology, Zabne, Silesian Medical School, Poland; stitute of Oncology, Gliwice, Silesian Medic1 School, Poland.
‘In-
The cardiotoxic activity of epirubicin, particularly in the course of a high-dose treatment, has been known for many years. In the group of 12 pts with lung cancer treated with high doses of epirubicin (130 mg/m2) the concentration of cardiospecific troponin T (cTnT) in serum has been stated. The concentration of troponin was defined for different total doses of the agent (the range: 200-1440 mg/m2). The raised concentration of this protein has not been stated at any of the treatment’s stages in the group of studied pts.
S45
1996 there were 1612 new lung cancer cases: 1373 (78.5/100000) for males and 239 (12.2/100000) for females. In the period 1978-1992 rates of lung cancer followed an increasing trend with the average annual increase 2.9% for males and 1.4% for females. The rates of lung cancer for males in Lithuania are comparable to those in East Europe and Baltic countries. The rates for females are still much lower than in West European countries. Lung cancer is the leading cause of death from cancer among Lithuanian men (29.6% in 1996) where almost 70% of patients die during the first year after the diagnosis of the disease. The high incidence and mortality rates of lung cancer is a challenge for oncologists and other health professionals in Lithuania to pay more attention to lung cancer problems. Lung carcinoma and old tuberculous lesions: coexistence or coincidence. Analysis of operation samples Radosavljevic T, Jakovic R, VuEinic V, Videnovic J, Djuric 0. Institute of Lung Disease Belgrade, Yugoslavia.
and
TB,
Clinical
Center
of Serbia,
Lung carcinoma (LC) and lung tuberculosis as coexisting diseases occurs in 2.5517% of patients with LC. Patients with granulomatous fibrotic tuberculous (TB) lesions and old TB focuses have a high risk for LC. The aim of the study was to analyze surgically treated patients with LC, who have old TB focuses. Pathohistological type LC, previous history of TB, localisation of LC, G differentiation N status, and connection between LC and old TB lesions were especially analyzed. Analysis was retrograde and comprises 1543 pts who were operated on for LC in the period 1992-1996 in our institution. From this group we singled out 106 (6.87%) pts with LC and old TB focuses in the operation sample. This group was separated into two groups: A: LC and old TB focuses had close contact and strong connection in operation samples (56 pts). B: Old TB focuses, were not found distant from LC, as coincidental findings in operation samples. There were no significant differences between groups A and B in sex, age of pts, type of operation, size of LC, localisation of LC, or previous history of TB. In group A adenocarcinoma was often statistically significant in relation to group B (P < 0.0001). In group B most frequently was Ca squamocellular. There were no differences between groups in N status and G differentiation LC. Conclusion: In group A a strong connection between LC and old TB focuses was found. The most frequent type was adenocarcinoma. There may also be strong influences between these two diseases in group A. In group B old TB focuses were only a coincidental finding. In this group most frequently was Ca planoceHular. Comparative analysis of certain parameters in different inftltrative lung changes of malignant and inflammatory etiology Kunosic J, Nedeljkovic B, Mitic T, Radivojevic S, Skodric V.
Lung cancer among men and women in Lithuania Jackevicius* A, Kurtinaitis J, Graciova E. Dept. of Thoracic
Institute of Pulmonary Yugoslavia.
Surgery,
For faster orientation and identification of the shortest diagnostic procedures, certain parameters were comparatively evaluated in three equal subgroups composed of 30 patients
Cancer
Registry,
Lithuanian
Oncology
Center.
Lung cancer has been the most common tumour among other malignancies in Lithuania during the past decades. In
Disease and TB, CC.7 of Serbia, Belgrade,
our department in the period 1994-1997. Altogether 64 cases (81%) were infectious, but only 17 (26%) were infections microbiologically defined, (50% gram negatives, 48% gram positives, 2% anaerobic), eight cases (10.1%) were fever of unknown origin (FUO), seven (8.9%) were fever not related to infection. In 11 cases (13.9%), febrile neutropenia was found, lasting less than 6 days, six cases (7.5%) having polymorphonuclear leukocytes less than 100/mm3. In 24% of cases is infection associated by obstruction - pneumonia. Effectiveness of antibiotic therapy in the first line treatment was 90%. According to the calculated trend curve we have to expect about 45 such new cases in 1998. Lung cancer: impact of mental conditions Semotanova M, Semotln’ J. ‘Independent - Bohnice 138, Czech Republic, and Psychiatry (Deceased).
Scientist, Prague 8 2Senior Resident in Neurology
Mental conditions, being as important in any human being as his somatic, social and spiritual personality traits, form part of prevention, therapy, and rehabilitation of lung cancer, in life regime, tumours, metastases, and following an operation. This is important especially in tobacco smoking and other dependencies, complicated with emotional and social stresses e.g. in passive smoking in the environment, at work, in the family, in a child group, etc. In the course of any therapy, a patient being aware of his cancer, an operation necessity or no more possibilities may result in dysfunction of somatic organs and a reduced resistance, depressive moods, and even suicide. Psychiatric consultation proves sometimes necessary. Mental support may improve cooperation, immunity system function, choice of an adequate, non-smoking party, finding new hobbies, and the assistance of a clergyman to find confidence in God and peace of mind. The same may be required in a rehabilitation period, and with permanent tobacco abstinence. Cardiospecific troponin T - the evaluation of its usefulness for staging the heart muscle’s injury in the course of a high-dose epirubicin chemotherapy Kozielski’ J, Bartnikowa’ W, Kaminski’ J, Deja2 R, Wygoda’ Z, Czernik2 E, Wydmarski2 J, Koterbicka2 A. ‘Clinic of Phthisiopneumology, Zabne, Silesian Medical School, Poland; stitute of Oncology, Gliwice, Silesian Medic1 School, Poland.
‘In-
The cardiotoxic activity of epirubicin, particularly in the course of a high-dose treatment, has been known for many years. In the group of 12 pts with lung cancer treated with high doses of epirubicin (130 mg/m2) the concentration of cardiospecific troponin T (cTnT) in serum has been stated. The concentration of troponin was defined for different total doses of the agent (the range: 200-1440 mg/m2). The raised concentration of this protein has not been stated at any of the treatment’s stages in the group of studied pts.
S45
1996 there were 1612 new lung cancer cases: 1373 (78.5/100000) for males and 239 (12.2/100000) for females. In the period 1978-1992 rates of lung cancer followed an increasing trend with the average annual increase 2.9% for males and 1.4% for females. The rates of lung cancer for males in Lithuania are comparable to those in East Europe and Baltic countries. The rates for females are still much lower than in West European countries. Lung cancer is the leading cause of death from cancer among Lithuanian men (29.6% in 1996) where almost 70% of patients die during the first year after the diagnosis of the disease. The high incidence and mortality rates of lung cancer is a challenge for oncologists and other health professionals in Lithuania to pay more attention to lung cancer problems. Lung carcinoma and old tuberculous lesions: coexistence or coincidence. Analysis of operation samples Radosavljevic T, Jakovic R, VuEinic V, Videnovic J, Djuric 0. Institute of Lung Disease Belgrade, Yugoslavia.
and
TB,
Clinical
Center
of Serbia,
Lung carcinoma (LC) and lung tuberculosis as coexisting diseases occurs in 2.5517% of patients with LC. Patients with granulomatous fibrotic tuberculous (TB) lesions and old TB focuses have a high risk for LC. The aim of the study was to analyze surgically treated patients with LC, who have old TB focuses. Pathohistological type LC, previous history of TB, localisation of LC, G differentiation N status, and connection between LC and old TB lesions were especially analyzed. Analysis was retrograde and comprises 1543 pts who were operated on for LC in the period 1992-1996 in our institution. From this group we singled out 106 (6.87%) pts with LC and old TB focuses in the operation sample. This group was separated into two groups: A: LC and old TB focuses had close contact and strong connection in operation samples (56 pts). B: Old TB focuses, were not found distant from LC, as coincidental findings in operation samples. There were no significant differences between groups A and B in sex, age of pts, type of operation, size of LC, localisation of LC, or previous history of TB. In group A adenocarcinoma was often statistically significant in relation to group B (P < 0.0001). In group B most frequently was Ca squamocellular. There were no differences between groups in N status and G differentiation LC. Conclusion: In group A a strong connection between LC and old TB focuses was found. The most frequent type was adenocarcinoma. There may also be strong influences between these two diseases in group A. In group B old TB focuses were only a coincidental finding. In this group most frequently was Ca planoceHular. Comparative analysis of certain parameters in different inftltrative lung changes of malignant and inflammatory etiology Kunosic J, Nedeljkovic B, Mitic T, Radivojevic S, Skodric V.
Lung cancer among men and women in Lithuania Jackevicius* A, Kurtinaitis J, Graciova E. Dept. of Thoracic
Institute of Pulmonary Yugoslavia.
Surgery,
For faster orientation and identification of the shortest diagnostic procedures, certain parameters were comparatively evaluated in three equal subgroups composed of 30 patients
Cancer
Registry,
Lithuanian
Oncology
Center.
Lung cancer has been the most common tumour among other malignancies in Lithuania during the past decades. In
Disease and TB, CC.7 of Serbia, Belgrade,