Monthly bibliography on prostaglandins prepared by the university of sheffield biomedical information service Sheffield S10 2TN, England

Monthly bibliography on prostaglandins prepared by the university of sheffield biomedical information service Sheffield S10 2TN, England

MONTHLY BIBLIOGRAPHY ON PROSTAGLANDINS PREPARED BY TNE UNIVERSITY OF SEEPFIELD BIONRDICAL INFOBNATION SERVICE SNEEPPIELDSlO 2TN. ENGLAND AUGUST 1983 B...

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MONTHLY BIBLIOGRAPHY ON PROSTAGLANDINS PREPARED BY TNE UNIVERSITY OF SEEPFIELD BIONRDICAL INFOBNATION SERVICE SNEEPPIELDSlO 2TN. ENGLAND AUGUST 1983 BGGKs.

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Pr~ta&aadlne and tke kidney Bioohe&stry, Physiology, Pharmacology a&d Clinical Applications Two- Day International Symposium Papers - C.K. Intarnrtional, Rome ISBU 0306410%0 - Boat, June 1981 BLLD Raf No Prostaglandlns 83/12356

Baylor, J., Lore, C-J., Thawles, A. Univ Sheffield, Dept Pharsuicol, Sheffield SlO ZTN, England J PHYSIOL LONDON 1983, 338 62P Urinary PGE2 excretion after acetasolamide administration in rats (Abstract)

Gulluar, B.C. NNLBI, Nypertens Endocrine Branch, Bethesda, Nd 20295, USA J AUTONONNBBV SYST 1983, g (1) 1 Tha interactions of proataglandins with the sympathetic nervous system - a review

Handa, M., Kondo, K., Suzuki, H., Saruta, T.* *Keio Univ. Sch Hed, Dept Internal Hed. Tokyo 108, Japan CLIN SC1 1983, 65 (1) 37-42 Urinary prostaglandin E2 and kallikreln excretion in glucocorticoid hypertension in rats

eee Boor, P. NRD TIJDSCNR GENEBSKG 1983, -127 (5) 206-9 The Nobel prize for medicine 1982. On essential fatty acida, prostaglandins and acctylsalicyclic acid (Dutch)

Aglietta, M., Piacibello, W., Gavosto, F. Univ Turin, Cattedra Patol Med, I-10126 Turin, Italy ACTA HAFJiATOL1983, u (6) 376 Responsiveness to prostaglaadin El of different subtypes of normal and pathological committed granulomonopoietic precursors

PROSTAGLANDINS R AND P Naylor. J.. Lota, C.J. Univ Sheffield, Dept Phansacol, Sheffield S10 2TN. S Yorkshire, England JPRARN PRARNACOL 1983, 25. (5) 299 The influence of prostaglandfn E2 and indomathacin on the renal corticomedullary solute gradient in the rat Dewhirst, P.B., Hess, D.E., Offenbather, S.. Goodson, J.M. Porsyth Dent Cc?, Dept Pharmacol, 140 Panway, Boaton, Ma 02115, USA J PIWODOlfT KM 1983, E (2) 156 Levels of prostrglradin E2, thromboxane, and prostacyclin In periodontal tissues Kom, J.R., Torres, D., Downie, E. Univ Connecticut, Sch Ned, Vet Adm Hcd Ctr, Dir Rbeumat Dis, Newington. Ct 06111, USA J CLIN INVEST 1983, 71 (5) 1240 Fibroblaet prost&andin-E2 synthesis - parsirtence of an abnormal phenotype after short-term exposure to mononuclear cell products Rlarskov, P., Gerstenberg, T., Ramires, D., Christensen, P., Hald. T. 7 Ludwig Hegnars Alle, DK-2630 TaaatNp, Denmark J UROL 1983. 129 (5) 1071 Prostaglandin~pe E activity dominates in urinary tract smooth muscle in vitro Matsude K.. Ohnishi K., Misaka E.. Yauaaki H. Sankyo Co Ltd. Biol Res Labs, Tokyo 140, Japan BIOOCBBWPNARNACOL 1983. 31 (8) 1347 Decrease of urinary prostaglandin E2 and prostaglandln FZalpha excretion by nouateroidal antiinflamatory drugs in rats. Relationship to anti-inflammatory activity

Elmarimi, A.A., Gibson, C.D., Morrow, D., Harteniuk, J., Gerloff, B.. Helancon, J. Michigan State Univ, Ctr Vet Clin, Dept Large Anim Surg, E Lansing, Hi 48824, USA AMER 3 VET RBS lY83, 46 (6) 1081 Use of prostaglandin FZalpha in the treatment of unobserved estrus in lactating dairy cattle Ramiressolares R., Lujan M.. Rodriguez R. Nat1 Unlv Mexico, Sch Med. Dept Pharmacol, Mexico City 04510, UP, Mexico PROC w PNARNACOL SOC 1983, a 345 Evidences for involvement of prostaglandins of the E-series in morphine physical dependence in the isolated ileum of the guinea-pig Gimeno A., Gonzales E., Franchi A., Gimeno M. Consejo Nacl Invest Clent 6 Teen, Ctr Estudios Farmacol 6 Principios Nat, Serrano 665-669, u-1414 Buenos Aires, Argentina PROSTAGLAND LEUK MED 1983, 11 (2) 151 Metabolic factors regulating the generation of prostaglandins El and E2 isolated rat uterus S&o K., Abe K., Seine M., Yasujflna M., Chiba S., Sato M., Haruyama T., Hiwatari H., tiotoT., Tajima J., Tanno M., Yoshlnaga I(. Tohoku Univ, Sch Hed, Dept Internal Ned 2, Sandal, Miyagi 980, Japan PROSTAGLAND LBUK MeD 1983, z (1) 189 Reduced urinary excretion of prostaglandin E in essential hypertension

Ignatowska-SwitalskaH. Acad Ned Warsaw, Dept Hypertens 6 Angiol, Nowogrodzka 59, PL-02006 Warsaw, Poland

PRGSTAGLAND LEUK MBD 1983, 11 (1) 233 Circadian rhythm of PGE2, ~Zalpba and 6-keto-PGFlalpha urinary excretion in healthy women nanabe Y., Okazaki T., Takahashi A. Kyoto Univ. Sch Med. Dept Obstet 6 uynecol, Sakyo ku, Kyoto 606, Japan GYNECOL OBSTET INVEST lY83, r, (6) 343 Prostaglandins E and Y in amuiotic fluid during stretch-induced cervical softening and labor at term PRECURSORS Hoffman. P.. Forster. W. Martin Luther U&v, l&pt Pharmacol h Toxicol, ~~~-4020 tlalle.E Gamany PROSTAGLANDIN LEUK NED 1983, 11 (1) 43 Effects of sunflowerseed oil, linseed oil, evening primrose oil and hydrogenated palm kernel oil in hypertension development in spontaneously hypertensive rats Cadenas, E., Sies, H., Naatainczyk W.. Ullrich, V. Univ Dusseldorf, Inat Physiol Chem 1, U-4000 Dusseldorf 1, W Germany ROPPE-SEYLEUS 2 PHYSIOL CdEH lY83, 364 (5) 519 Singlet oxygen formation detected by low-level chemiluminescence during rnsymic reduction of prostaglandin GL to H2 Arachidonic Acid Henderson, W.R., Hubbard, W.C., Klebanoff, S.J. Univ Washington, Sch Med. Dept ded. Seattle, Wa 98195, uSA LIPIDS 1983, s (5) 390-391 Iodination of arachidouic acid by the iron/H202/lodide system Rarvey J., Osborne D.J. Lilly Res Ctr Led, Erl Wood Hanor, Wlndlesham GU20 6PH, England J PRARXACOL MRTN 1983. 9_ (2) 147 A rapid method for detecting inhibitors of both cycle-oxygenase and lipoxygenase metabolites of arachldonlc acid Weichman, B.H., Muccitelli, R.d., Tucker. S.S., Wasserman, H.A. S K h F Labs, Jept Pharvacol, Philadelphia, Pa 19101, USA J PRARMACOL EXP THER l!lU, g (L) 310 Effect of calcium antagouists on leukotriene-D-4-inducedcontractions of the guinea-pig trachea and lung parenchyma 'fakenava,T., Ronma, Y., lagsi, Y. Univ Tsukuba. Inst Basic Wed Sci, Sakura, Ibaraki 305, Japan J Ii%WNOL 1983, 130 (6) 284Y Role of Ca2+ in phaaphatidylfnoaitol response and arachldonic acid release in forloylatedtripeptide- or Ca2+ ionophore A23187-stis?ulatedguinea pig neutrophils

Smith, D.M., Walsh, C.E., Dechatelet, L.R., Waite, M. Wake Forest Univ, Bowman Gray Sch Med. Dept Biochem, Winston Salem, NC 27103, USA INFEC IMMUNITY 19d3, g (3, 1230-1233 Arachidonic acid metabolism in polymorphonuclear leukocytes from patients with chronic granuloioatous disease Nishieawa, E.E., Williams, D.J., Connell, C.L. Upjohn Co, Kalamazoo, Mi 49001, USA THROMB ~8s 1983, 30 (3) 289 Arachidonate induced aggregation of rat platelets may not require prostaglandin endoperoxides or thromboxane A2 Fforita.I., Takahashi, R., Ito, H., Oriloo,H., Murota, s. Tokyo Metropolitan Inat Gerontol. Dept Pharmacol, 35-2 Sakaecho, Itabshi ku, Tokyo 173, Japan PROSTAGLANDIN LEUK NED 1983, 11 (1) 33 Increased arachidonic acid content in platelet phospholipids from diabetic patients Ody, C., Duval, D.* aHop Necker, INSEBM, U7, Dapt Physiol 6 Pharmacol, F-75730 Paris 15, France PROSTAGIANDIN LEUK MED 1983, II. (1) 63 Arachidonate incorporation and prostaglandin production in cultured endothelial and smooth muscle cells from pig aorta Uotila, P., Dahl, M., Matinalo, M., Puustinen, T. Univ Turk". Dept Physiol, ~~-20520 Turk" 52, Finland PROSTAGLANDIN LEUK MFD 1983, 11 (1) 73 The effects of aspirin and dipyridamole on the metabolism of arachidonic acid in human platelets Musch, M.W., Kachur, J.F., Miller, R.J., Field, H.*, Stoff, J.S. *Univ Chicago, Dept Pharmacol d Physiol Sci. Chicago, 11 60637, USA J CLIN INVEST 1983, G (5) 1073 Bradykinin-stimulatedelectrolyte secretion in rabbit and guinea pig intestine - involvement of arachidonic acid metabolites Ahmed T., Oliver W. Mt Sinai Med Ctr, Div Pulm Dis, Miami Beach, PI 33140, USA AM REV RFSPIR DIS 1983, 127 (5) 566 Does slow-reacting substance of anaphylaxis mediate hypoxic pulmonary vasoconstriction Pace-Asciak, C.R., Granstrom, E., Samuelsson. B. Hasp Sick Children, Rea Inst. Toronto, Ontario, Canada M5G 1X8 .IBIOL CHEM 1983, 258 (11) 6835 Arachidonic acid esides. Isolation and structure of two hydroxy epoxide intermediates in the formation of 8,11,12- and 10,11,12- trihydroxyeicosatrienoic acids

Chacos, N., Capdevila, J., Falck, J.R., Manna, S., Martin-Wixtrom, C., Gill, S.S., Hammock, B.D., Estabrook, R.W. univ Texas, Hlth Sci Ctr, SW Med Sch, Dept Biochem, Dallas, TX 75235, USA AKCH SIOCHEM BIL)PHYS1983, G (2) 639 The reaction of arachidonic dcid epoxides (epoxyeicosatrlenoicacids) with a cytosolic epoxide hydrolase Holwn, K.T., Johnson, S.B., Gerrard, J.M., Mauser, S.id., Kupchosandberg, S., Brown, D.M. Univ Minnesota, Hormel Inst, Austin, Mn 55912, USA PROC NATL ACAU SC1 US - BIOL SC1 1983, g (8) 2375 Arachidonic acid deficiency in streptozotocin-induceddiabetes Sate, J., Ishinaga, M., Kite, M., Kyoto Univ, Food Sci Res Inst, Uji, Kyoto 611, Japan AGR BIOL CHEM TOKYO 1983, 47 (4) 887 Perturbation of arachidonic acid metabolism by erucic acid in rat heart: differential response of the sexes Oregan, S., Turgeon, C. univ Montreal, Hop St Justine, Dept Pediat, Div Nephrol, Nephrol Serv, Montreal, Quebec, Canada HAT 1C5 PATHOL RRS PRACT 1983, 176 (2-4)LY7 Arachidonic acid infusion in rabbits - renal pathologic alterations Moqbel R., Sass-Kuhn S.P., Goetzl F.J., Kay A.B.* *&rompton Hosp, Inst Cardiothorac, Depc Allergy 6 Clin Immunol. London SW3 6HP, England CLIN EXP IMMUNOL 1983, 51 (3) 519 Enhancement of neutrophil- and eosinophil-mediated complementdependent killing of schistosomula of Schistosoma mansoni in vitro by leukotriene B4 Dahlen, S-E. Karolinska Inst, Dept Physiol 1, S-10401 Stockholm 60, Sweden ACTA PHYSIOL SCANU 1983, Suppl 512 l-51 Pulmonary effects of leukotrienes Green R.H., Lambeth P.F. Glaxo Grp Res Ltd, Dept Chem Res, Greenford UB~ OHE, Middx, England TEL-RAHEURONlY83, 39 (10) 1667 Leukotrienes (Tetrahedron Report Number 148) Corey E.J., Lansbury P.T. Harvard Univ. Dept Chem, Cambridge, Ma 02138, USA .I AM CHEM SOC 1983, 105 (12) 4093 Stereochernicalcourse of %lipoxygenation of arachidonate by rat basophil leukemic cell (RBL-1) and poteto enzymes Swendsen, C.L., Ellis, J.M., Chilton, P.H., O'Flaherty, J.T., Wykle, R.L. Wake Forest Univ, Bowman Gray Sch Med, Dept Biochem, Winston Salem, NC 27103, USA BIOCHEM BIOPHYS RES COMMUN 1983, -113 (1) 72

b-D-alkyl-L-acyl-sn-glycerd-+phosphocholine: A novel source of drdchidonic acid in neutrophils stimulated by the calcium ionophore ~23187 L.Y., Tai, H.H.* *Univ Kentucky, Co11 Pharm, Div Med Chem & Pharmacognosy, Lexington, Ky 40536, USA BIOCHEM BIUPHYS RES COMrlUN1983, G (1) 241 Diglyceride/monoglyceridelipase pathway is not essential for arachidonate release in thrombin-activatedhuwan platelets Chau,

Naccache, P.H., Molski, T.F.Y., Volpi, M., Hackin, W.M., Becker, E.L.. Sha'afi, R.I. Univ Connecticut, Ctr Hlth, i)ept Pathol, Farmington, Ct Db032, USA J CELL PHYSIOL 1983, 115 (3, 243 Inhibition of chemotactic factor-induced neutrophil responsiveness by arachidonic acid simmons P.M., Salmon J.A.*, Moncada S. *Wellcome Res Labs, Dept Prostaglandin Res, Langley Court, Beckenham BR3 3BS, Kent, England BIUCHEM PHARMACUL lY83, 32 (8) 1353 The release of leukotriene S4 during experimental inflallnnetion Jonnson H.ti.,McNee M.L., Johnson M.A., Miller M.D. Upjohn Co, Hypersensitiv Dis Res, 301 Henrietta SC, Kalamazoo, Mi 4YUU1, USA INT ARCH ALLERGY APYL IMMUNOL lY83, c(3) 214 Leukotriene C4 and dimethylphenylpiperazinium- induced responses in canine airway tracheal muscle contraction and fluid secretion Mikhailidis, D.P., Jeremy, J.Y., Dandona, P, Royal Free Hosp h Sch Med, Dept Chem Pathol, Metabol Unit, London N~l32QQ, England CLIN SC1 1983, 65 (1) 103-104 Augmentation of prostaglandin production by linoleic by linoleic acid in man (Letter) Leitch, A.ti.,Lewis, K-A., Corey, E.J., Austen, K.F. Harvard Univ, Scn Med. i)epttied, Boston, Ma 02115, USA CHEbT 1983, E (5, (Suppl) 815 Of Quantitation and CharacteriZatiOn leukotriene products released followin& immunologic stimulation of human lun8 cells in vitro Albert, R.K., Greenberg, G.H., Henderson, w. Univ Washington, Sch tied,Uept Med. Seattle, Wa 9olY5, USA CHEsP 1983, g (5) (Suppl) 85s Leukotriene C4 and 04 increase pulmonary vascular permeability in excised rabbit Lungs

Creese B., Bach H.* *Upjohn Co, Dept tlypersensitiv Dis F.es, Kalamseoo. Ml 49001, USA PROSTAGLAND LEUK MED 1983, & (2) 161 Hyperreactivity of airways by smooth muscle produced in vitro by leuko-

Fitzgerald G.A., Pedersen A.1(., Patron0 C. Vanderbilt Univ, Ned Ctr, Sch Med, Div Clin Pharmacol, Nashville, Tn 37232, USA CIBCULATION 1983, 67 (6) 1174 Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease

Minter, d., Frampton, G., Bennett, A., Machin, S.J., Cameron, J.S. Guys Hasp, Sch Med. Dept Haematol, London SE1 9KT, England THROHB RES 19M3, Jo (3) 2o> Synthesis of thromboxane B2 in uraemia and the effects of dialysis

eThosas Jefferson Univ, Jefferson Med Coll, Dept Physiol, Philadelphia, Pa 19107, USA DIABETOLOGU 1983, 14 (5) 372 Vascular responsiveness and eicosanoid production in diabetic rats

Reeves, W., Demers, L., Wood, M., Skarlatos. S.. Copenhaver, f., Whitesell, L., Luderer, J. Radomski M., Moncada S. Penn State Univ, Milton S Hershey Med Wellcome Res Labs, Dept ProstaCtr, Div Cardiol, Hershey, Pa 17033. glandin Res, Langley Court, Beckenham USA BR3 3BS, Kent, England PROSTAGLANDIN LEUK M8D 1983, 11 (1) 1 The release of thromboxane AL and THROM8 RES 1983, 30 (4) 383 An improved method for washing Of prostacyclin following experimental human platelets with prostacyclin acute pulmonary embolism

Anggard E. Karolinska Inst. Dept Alcohol 6 Drug Addict Res, S-10401 Stockholm 60, Sweden PHARMACOL BIOCHEM BEHAV 1983, 18 SUPPL 1 401 Ethanol, essential fatty acids and prostaglandins

Gullner, H.G., Graf, A.K., Gill, J.R., Mitchell, M.D. NHLBI, Hypertens Endocrine Branch, Bldg 10, Room SClU3, Bethesda, rid 20205, USA CLLN SC1 lYM3, 65 (1) 43-46 Hypokalaemia stimulates prostacyclin synthesis in the rat

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Berry, C.N., Hoult, J.R.S. Univ London Kings Coil, Dept Pharmacol, London X2R 2LS, England PHARMACOLOGY 1983, & (6) 324 6-keto-prostaglandin El: Its formation by platelets from prostacyclin and resistance to pulmonary degradation

Roth,

D.M., Refbel, D.K., Lefer,

A.&*

Ueki. T.. Andersson, K-E., Brandt, L., idviasson, L., Ljunggren, B. Univ Lund Hosp. Dept Clin Pharmacol, S-22185 Lund, Sweden J CEReBR BLOOD FLOW METABOL 1983, 2 (2) 238 Responses of isolated feline and human cerebral arteries to prostacyclln and some of its metabolites Andersson, R.G.G., Saldeen, K., Saldeen, T. Linkoping Univ. Dept Pharmacol, S-58183 Linkoping, Sweden THP.OMB RRS 1983, 30 (3) 213 A fibrin(ogen) derived pentapeptide induces vasodilation, prostacyclln release and an increase in cyclic AMP Hirose, T., Aoki, E., Domae, M., Ishibashi, M., Ikeda, T., Tanaka, E. Kyushu Univ, Fat Fled, Dis Chest Res Inst, liigashi ku, Fukuoka 812, Japan PROSTAGLANDIN LEUK MED 1983, 11 (1) 51 The effect of prostacyclln infusion on increased pulmonary vascular permeability following microembolisation in dogs Longenecker G.L., Mankad V. Univ S Alabama, Co11 Med, Dept Pharmacol, Mobile, Al 36688, USA PEDIATRICS 1983, z1, (5) 860 Decreased prostacyclin levels in sickle cell disease (Letter) Mehta P., Albfol L. Univ Florida, Co11 Med. Dept Pediat, Gainesville, Fl 32610, USA PEDIATRICS 1983, 11. (5) 861 Decreased prostacyclin levels in sickle cell disease - Reply

Karacsony G., Balint G.A., Lukacs G., Varro V. Univ Med Sch Szeged, Dept Med 1, H-6701 Szeged, Hungary ACTA PHYSIOL ACAD SC1 HUNG 1982, 60 (3) 143 Modification of the cytoprotective effect of prostacyclin on gastric epithelial cells of rats by colchicine Philp R., Paul M. Univ Western Ontario, Dept Pharmacol & Toxicol, London, Ontario, Canada N6A 5C1 PROSTAGLAND LEUK MEL) 1983, II. (2) 131 Low-dose aspirin (ASA) renders human platelets more vulnerable to inhibition of aggregation by prostacyclin (PGl2) Thromboxanes Usui, H., Kurahashi, K., Ashida, K., Fujiwara, M. Kyoto Univ, Fat Med, Dept Pharmacol, Kyoto 606, Japan IRCS MED SCI-BIOCHEM 1983, 11 (5) 418 Acetylcholine-induced contractile response in canine basilar artery with activation of thromboxane A2 synthesis sequence

Pagella, P.G., Bellavite, O., Agozzino, S., Dona, G.C., Cremonesi, P., Desantls, F. Orchard, MA., Ritter, J.M., Shepherd1, Italfarmaco Spa, Pharmacol h Toxic01 G.L., Lewis, P.J. Lab, Res Grp, Viale F Testi 330, Royal Postgrad Ned Sch. Dept Clin I-20126 Milan, Italy Pharmacol. London W12 OHS, England ARZtiEIM-FOKSCd-DRUG RES 1Y&3, 33-l BR J CLIN PHARMACOL 1983, g (5) 509 (5) 716 Cardiovascular and platelet effects Pharmacological studies of imidaaole In man of BW 245C. a stable mimic of L-hydroxybensoate (ICF l&Z), an epoprostenol (PG12) antiinflammatory compound with an action on throoboxane-A2 production

Viinikka, L., Salokannel, J., Ylikorkala ". Univ Culu, Dept Clin Chem, SF-YULLJ oulu 22, Finland PRUSTA&ANDIN LEUK MEti lYd3, II_ (1) 45 Effect of prolonged treatment with acetylsalicyclic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects Hechtman, H.E., Huval, W.V., Hathieson, MA., Stemp, L.I., Valeri, C.R., Shepro, Il. Brigham 6 Womens Hosp, Boston, Ma 02115, USA SURG CIIN N ANBR 1983, 63 (2) 263 Prostaglandin and thromboxane mediation of cardiopulmonary failure Kadowitz, P.J., Nandiuada, P.A., Spannhake, E.W., Rosenson, R.zi., McNamara, D.B., Hyman, A.L.* *Tulane Univ, Sch Med. Dept Pharmacol, New Orleans, La 70112, USA CHEST 1983, 83 (5) (Suppl) 755 Pulmonary vascular responses to thromnoxane AL as unmasked by OKY-1581 Harlan, J., Winn, K., tieaver,J., Hildebrandt, J., Harker, i. Univ Washington, Seattle, 'da Y&lYS, USA

CHEST 1‘183,g (5) (Suppl) 755 Selective blockade of thromboxane A2 synthesis during experimental E coli bacteremia in the goat Garcia, R.S., Minnear, P.L., 6izios, R., Johnson, A., Nalik, A.8. CHEST 1983, g (5) (Suppl) 76s Kale of thromboxane in the pulmonary response to pulmonary microembolizatlon Hartung, H.P., Toyka, K.V. Univ Dusseldorf, Dept Neural, Neuroimmunol Lab, D-4000 Dusseldorf 1, W Germany EUR J PHARMACOL 1983, 89 (3-4) Activation of macropheges by substance P: induction of oxidative burst and thromboxane release Ouwendujk, R.J.T., Zijlstra, F.J., Wilson, J.H.P.*, ilonta, I.L., Vincent, J.E., Stols, E. *univ tIosp DiJksiyt, Dept Lnternal Med 2, 3015 GLI Rotterdam, Netherlands EUR J CLIN INVEST lYd3, g (3J 227 liaised plasma levels of thromboxane 82 in systemic mastocytosis

MBTABOLITES steffenrud S. univ naval, ctr

~osp, ctr Rech Endocrinol Molec, Quebec City, Quebec, Canada GlV 4GL DRUG METAB DISPOSITION 1983, 11 (3) 255 Metabolism 9-methylene

of 9-deoxo-16,16-dlmethylprostaglandin-E2 in

humans Brennecke, S.P., Turnbull, A.C. Univ Oxford, John Radcliffe Matern Hasp, Nuffield Dept Obstet 6 Gynaecol, Oxford OX3 9DU, England J PHYSIOL LONDON1983, 338 45P Maternal peripheral plasma prostaglandin E2 metabolite and prostaglandin FZalpha metabollte coocentrations in the late pregnant ewe in relation to fetal vascular catheterization surgery (Abstract) Vlasses P., Ferguson R., Smith J., Rotmensch H., Swanson 8. Thomas Jefferson Univ Hosp, Philadelphia, Pa 19107, USA PROSTAGLANDLEUK MED 1983, 11 (2) 143 Urinary excretion of prostacyclin and thromboxane A2 metebolites after angiotensin converting enzyme inhibition in hypertensive patients

RELATED ENZYMES Pagels, W.R., Sachs, R.J., Marnett, L.J.*, Dewitt, D.L., Day, J-S., Smith, W.L. *Wayne State Univ. Dept Chem, Detroit, Mi 48202, USA J BIOL CHEM1983, 258 (10) 6517 Immunochemical evidence for the involvement of prostaglandln B synthase in hydroperoxide-dependent oxidations by ram seminal vesicle microsones Slvarajah, K., Jones K.G., Pouts, J.R., Devereux, T., Shirley. J-E.,

Eling, T.E. NIEHS, Pulm Funcc & Toxic01 Lab, POB 12233, Res Triangle Pk, NC 27709, USA CANCERRI% 19’33, 43 (6) 2632 Prostaglaodin syathetase and cYtochrome P-450-dependent metabolism of (+/-)benzo(a)pyrene 7,8-dihydrodiol by enriched populations of rat Clara cells and alveolar type II cells

Perchonock, C.U., Finkelstein, J.A., Uzinskas, I., Gleason, J.G., Sarau, J.M., Cieslinski, L.B. s K b P Labs, Div Res 6 Dev, Philadelphia, Pa 19101, USA TETRAdEDRON LETT 1983, 24 (24) 2457 Dimethyleicosatrienoicacids: inhibitors of the 5-lipoxygenase enzyme

aaerd, S.A., Mitchell, 14.1). Univ Texas, Hlth sci Ctr, bLI,+edYch, Cecil H b Ida Green Ctr &eprod tiiol Sci, Dallas, TX 7>L35, USA CLL,\I EXP HYPORI‘ENSB aYPERTENs lYd3, 2 (1) 103 Lipoxygenase activity in human uterine and intrauterine tissues: new prospects for control of prostacyclin production in pre-eclampsia

Huddleston C.B., Lupinetti F.M., Laws K.H., Collins J.C., Clanton J.A., Hawiger J.J., Oates J.A., Hammon J.W.* *Vanderbilt Univ, Med Ctr, Dept Cardiac 6 Thorac Surg, Nashville, Tn 37212, USA CIRC RES 1983, 12. (5) 608 The effects of RO-22-4679, a thromboxane synthetase inhibitor, on ventricular fibrillation induced by coronary occlusion in conscious dogs

SYNTHESIS AND RELEASE Morisaki. N.. Lindsav. J.A.. Mile. . . G.E., Co;nweil, D.G.-' Ohio State Univ, Dept Physiol Chem, Columbus, Oh 43210, USA LIPIDS 1983, E (5) 349-352 Fatty acid metabolism and cell proliferation: III. Effect of prostaglandin biosynthesis either from exogenous fatty acid or endogenous fatty acid release with hydralazine

Mevkh, A.T., dasevich, V.V., I., Varfolomeev, S.D. Yarving, AN Belozerskii Molec Biol 6 Bioorgan Chem Lab, Moscow, USSR BIOCHEMISTRY.ENGL TK 1982, 41. (11) PT.2 1574 Inactivation of prostaglandin endoperoxide synthetase from the microsomal fraction of human thrombocytes during the reaction Kitahara N., Haruyama H., Hata T., Takahashi S. Sankyo Co Ltd, Fermentat Res Labs, l-2-58 Hiromachi, Shinagaws Ku, Tokyo 140, Japan J ANTIBIOT 1983, a (5) 599 The structures of thielavins A, B and C. Prostaglandin synthetase inhibitors from fungi Bourgain R.H., Andries R., Maes L. Vrije Univ Brussel, Sch Med, Dept Physiol & Physiopathol, B-1090 Brussels, Belgium HAEMOSTASIS 1983, 12. (2) 102 Effect of cyclooxygenase inhibition on platelet-vessel wall interaction

Walter, N.J., Kunkel, S.L., Lynch, J.P.*, Ward, P.A. *Univ Michigan, Med Ctr, Dept Pathol, Ann Arbor. Mi 48109, USA CHEST 1983, E (5) (Suppl) 79s Production of cyclooxygenase products by alveolar macrophages in Gimeno, H.P.. Shattner, M.A., Borda, pulmonary sarcoidosis E., Gimeno, A.L.*, Lazzari, M.A. *Ctr Estud Parmacol & Princlpios, Fukumoto S., ‘Tanaka K. Buenos Aires, Argentina Kyushu Univ 60, Fat Med. Dept PROSTAGLANDIN LEUK mD 1983, 11 (1) Pathol, Higashf ku, Fukuoka (112, 109 Japan Lipoxygenaae inhibitors alter PROSTAGLAND LEUK NED 1983, 11 (2) aggregation and adhesiveness of 179 human blood platelets from aspirin- Protective effects of thromboxane A2 treated patients synthetase inhibitors on endotoxin shock Mete, s., Vanrollins, M., Strife, R., Pujimoto, W.. Robertson, R.P. Kinney E., Draganls T., Luderer J., Univ Colorado, Hlth Scl Ctr, Div Demers L.* Clin Pharmacol, Denver, Co 80262, *Penn State Univ. Milton S Hershey USA Med Ctr, Dept Pathol, Hershey, Pa J CLIN INVEST 1983, z (5) 1191 17033, USA Lipoxygenase pathway in islet PROSTAGLAND LEUK MED 1983, fi (2) endocrine cells - oxidative meta213 bolism of arachldonic acid promotes Mechanism of action of amrinone: insulin release Role of thromboxane synthecase inhibiti(,n

Hartung, H.P., Hadding, U., HitterSuermann, Gemsa, D. Univ Mainz, Inst ,%edMicrooiol, D-6500 tiainz,J Germany J IMMUNOL 1983, 130 (6) 2861 Stimulation of prostrgiandin E and thromboxane synthesis in macrophages by purified C3b Chandler, D., Giri, S*, Chen, Z., Hyde, D. *Sch Vet Med, Dept Pharmacol h Toxicol, Davis, Ca 95616, PKOSTAGLANDIN LEUK IYBD1963, c (1) 11 The in vitro synthesis and degradation of prostaglandins during the development of bleomycin-induced pulmonary fibrosis in hamsters Harper, M.J.K.. Khodr, G.S., Valenzuela, G. Unlv Texas, Hlth Sci Ctr, Uept Obstet & Gynecol, San Antonio, TX 78284, USA PROSTAGLANDIN LEUK clEl) 1983, E (1)

.LLL^.

Prostaglandin production by human term placentas in vitro Garaci, C.R., Favalli, C., de1 tiobbo, V.,

Garaci,

E.*,

Jaffe,

B.ul.

*Univ Rome, Sch Med, Inst Microbial, Piazrak Aldo tloro5, L-00165 Rome, Italy SCIENCY 1963, 220 (46U1) 1103 IS tnymosin action mediated by prostaglandin release? Taylor, L., Menconi, M.J., Polgar, 9. Boston Univ, Sch Ned, Dept Blochem, Eoston, Ma 02118, USA J BIOL CHEM 1983, 258 (11) 6855 The participation ofhydroperoxldes and oxygen radicals in the control of prostaglandin synthesis Evans, M.H., Pace, C.S., Clemants, R.S.* *Vet Adm Med Ctr, Metab Res Lab, Birmingham, Al 35233, USA DIABETES 1983, 32 (6) PTl 509 Endogenous prostaglandin synthesis and glucose-induced insulin secretion from the adult rat pancreatic islet

Arroyo, v., Planas, 8.. Gaya, J., Deulofeu, R., Rimola, A., PerezAyuso, R.l4.,Bivera, P., Rodes, J. tlospclin & provincial, Unidad Bcpatol, Barcelona 36, Spain EIJRJ CLIN INVRST 1983, 13 (3) 271 Sympathetic nervous activity, renin-angiotensinsystem and renal excretion of prostaglaadin 132 in cirrhosis. Relationship to functional renal failure and sodium and water excretion Kehler, C.H. Univ Manitoba, Hlth Sci Ctr, Dept Anaesthesia. Winnipeg, Manitoba, Canada R3E 023 CAN ANABSTH SOC J 1983, 30 (3) Pt 2 514 Prostaglandins and anaesthesia PROSTAGLANDINS AS DRUGS Collins. P.W.,Dajani. E.Z., Pappo, R., Gasiecki, A.P., Bianchi, R-G., Woods, E.M. Int Plant Res Inst. San Carlos, Ca 94070. USA J MF,D-CHEN1983, 26 (6) 786 Synthesis and gastric antisecretory properties of 4,5-unsaturated derivatives of 15-deoxy-16-hydroxy16-methylprostaglandinEl Bundy, G.L., Morton, D.R., Peterson, D.C., Nishizawa, ErE., Miller. W.L. UpJohn Co, Dspt Exptl Se1 1, Kalamacoo, Mi 49001, USA J MRD CHEM 1983, 26 (6) 790 Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues Luther E.R., Gray J.H., Young D., Gouln J.A., Lorrain J. Dalhousie Univ, Dept Obstet 6 Gynecol, Div Periaatal Med, Halifax, NS, Canada B3H lW3 CM MED ASSN J 1983, 128 (10) 1189 Comparison of naturaland synthetic prostaglandin E2 tablets in labour induction gohen M.H., Nihill M.R. Texas Childrens Hasp, Dept Pediat Cardiol, aouston, TX 77030, USA PEDIATRICS 1983, 71 (5) 842 Postoperative ketotic hyperglycemia during prostaglandin-El infusion in infancy Chu, Y.H. et al CHUNG KU0 YAO LI HSURH PA0 1982, 2 (4) 256-60 Action of 15-methyl-prostaglandinF2 alpha on progesterone receptors and estradiol receptors in rabbit uterus (Chinese) Manullova, I.A. et al AKUSH GINEKOL (MISK) 1983, (1) 54-5 Effect of lS-me-prostaglandinP2 alpha on the release of endogenous prostaglandin F2 alpha and *he concentration of estrogen and progesterone receptors in the human endometrium (Russian) Bergmann, M. Fredrich Schiller Univ, Bereichs Med. Inncre Msd Klin, DDR-6902 Jene, E Germany DEUT GESUND-2 KLIN MRD 1983, 3s (16) 625

On the influence of prostaglandins on the upper digestive tract (German) Varma, T.R., Giannacodimos, G., Luthra, P. St George8 Hasp, Sch Med, Dept Obstet 6 Gynaecol, London SW17 OQT, England J OBSTET GYNABCOL 1983, 2 (4) 234 Induction of labour with an uofavourable cervix - a comparison of 2 mg prostaglandin E2 pessaries with amniotomy and oxytocin infusion Hansen, T.M., Lerche, A., Kassis, V., Lorenzen, I., Sondergaard. J. Univ Copenhagen, Hvidovre Hosp. Dept Rheumatol, DK-2650 Hvidovre, Denmark SCAND J RHEUMATOL 1983, &?_ (2) 85 Treatment of rheumatoid arthritis with prostaglandin El precursors cis-linoleic acid and gamna-linolenic acid Ramesh, S.. Bhatnagar, B., Ranjana, S.K. SMS Med Coll, Dept Obstet 6 Gynaecol, Jaipur 302001, India INDIA J M&I R8S lY83. II. 642 Role of intramyometrial prostaglandin-El in management of 3rd stage of labour Andrinopoulos G.C., Mendenhall H.W. Univ S Alabama, Med Ctr, Dept Obstet 6 Cynecol, Mobile, Al 36617, USA AM J OBSTET GYNRCOL 1983, 146 (2) 217 Prostaglandin-F2-alphain the management of delayed postpartum hemorrhage Fayemi A., Schulman H.*, Mitchell J., Fleischer A. *Jacobi Hosp, Dept Gynecol 6 Obstet, Bronx, NY lU461, USA AM J OBSTET GYNECOL lY83, 146 (2) 219 Internal and external cervical OS dilatation with vaginal l>-methyl prostaglandin-F2-alpha Herman A.G. Univ Instelling Antwerp, Fat Med. B-2610 Wilrijk, Belgium ACTA CLIN BELG 1983, 3s (2) 75 Clinical use of prostaglandins (Editorial) Pardy B.J., Eastcott H.H.G. Charing Cross Hosp, Dept Surg, London W6 ERF, England WORLD J SURGERY 1983, L (3) 353 Prostaglandin therapy in severe limb ischemia Axelrod L. Diabetes Unit, Massachusetts Gen Hosp. Boston. Ma 02114, USA LANCEr 1983, z (8342) 165 Vasodilator prostanoids and ACTHdependent hypertension (Letter) Ruwart M.J., Sammons D.W., Kolaja G.J., Rush B.D., Priedle N.M., Adams L.D. Upjohn Co. Dept Exptl Sci. Kala~.~zoo, Mi 49001, USA RBS COMMON CHEM PATHOL Pm.I 1983, 0 (2) 233

Alloxan-induced hyperglycemia in rats is reduced by 16, 16-dimethyl- PGEL Butler W-K., aoyd K.D. Cornell Univ, Dept Anim Sci, Ithaca, NY 14853, USA BIOL REPROD 1983, a (5) lob1 Relaxin enhances synchronization of' parturition induced with prostaglandin Flalpha in swine Mikhailidis, D.P., Hutton, R.A., Jeremy, J.Y., Dandona, P. Royal Free Hosp 6 Sch Med, Dept Chem Pathol, London NW3 2QG, England MICROCIRCULATION lY83. 2 (4) 413 Cooling decreases the efficiency of prostaglandin inhibitors of platelet ageregation - a factor of possible relevance in cold induced pathology Bretzlaff, K.N., Hill, A., Ott, R.S. Univ Illinois, Co11 Vet Med, L)eptVet Clin rled,Urbana, I1 blLIO1,LlSA AMF& J VET HES lY83, 46 (6) 1162 Induction of luteolysis in goats with prostaglandin FZalpha Sugio, K., Ualy, J.W. NIADDKD, Bioorgan Chem Lab, Bldg 4 Hm 212, Bethesda, Wd 20205, USA LIFE SC1 1983 22 (1) 65 Effect of forskolin on alterations of vascular permeability induced with bradykinin, prostaglandin El, adenosine histamine and carrageenin in rats Williams L.M., Hollingsworth M., Dukes M., Morris I.D. Univ Aston, Dept Pharm, CRC Exptl Chemotherapy Grp, Birmingham B4 7ET, England J ENJOCKINWL 1983, 97 (2) 283 Fluprostenol-induced softening of the cervix of the pregnant rat Kudryashov, S.A., l.eling,N.ti., Mel'nikova, V.I., Pivnltskii, K.K. Acad Med Sci USSR, Cardiol Sci Ctr, Moscow. USSn BULL EKP PIOL MEI)ENGL TK lY82, E (11) 1471 Antiaggregating activity of some synthetic prostaglandins

Rettenmaier, M.A., Hanson, F.W. Univ California Irvine, Sch Ned, Dept Obstet h Gynecol, Orange, Ca 92668, USA SURG GYNECOL OBSTET lY83, iS6 (5) 58> A comparative study of 2 types of prostaglandins for-abortioh-during the 2nd trimester Maria B., Fayette E., Stampf F., Gandon C., Gantrel J., Barrat .J.* *Hop St Antoine, Serv Gynecol Obstet, F-75571 Paris 12, France J GYNECOL OBSTET BIOL REPRO0 1983, 12 (2) 183 Ripening the cervix by using FZ-alpha prostaglandin before induction of labour in paLhologica1 pregnancies (French) Walker, F.M.N. AkC, Inst Anim Physiol, Cambridge CBL 4AT, England P&S VET SCI lYc(3,-'G (3) 1dU Lactation and fertility in Goats after the induction of parturition with an analoSue of prostaglandin-P2alpha, cloprostenol

Hayashi M., Fujita A., Satoh S. Tohotu Univ, Inst Pharmaceut, Dept Pharmacol, Sendai, Miyagi 980, Japan JPN J PHARMACOL 1983, 33 (3) 563 Different mode of action between norepinephrine and phenylephrine on prostaglandin synthesis by dog renal inner medullary slices Cheung, H.S., Halverson, P.B., McCarty, D.J. Med Co11 Wisconsin, Dept Ned, Rheumatol Sect, Milwaukee, Wi 53226, USA PROC SOC EXP BIOL MED 1983, -173 (2) 181 Phagocytosis of hydroxyapatite or calcium pyrophosphate dihydrate crystals by rabbit articular chondrocytes stimulates release of collagenase, neutral protease, and prostaglandins E2 and FZalpha Rogers, S.P., Khalid, B.A.K., Funder, J.W$, Larkins, R.G.* *Univ Melbourne. Repatriation Gen Hosp, Dept Med,~Heihelberg, Vie 3081. Australia CLIN'SCI 1983, 65 (1) 85-67 Adrenalectomy and glucocorticoid administration in viva do not affect production of 6-oxopiostaglandin Flalpha by rat aortae Rennard, S.I., Moss, J., Oberpriller, J., Horn, B., Stier, L., Ozaki, T., Crystal, R.G. NBLBI, Bethesda, Md 20205, USA CHEST 1983, 3 (5) (Suppl) 92s Fibroblasts: Important producers and targets of inflammatory prostaglandios in the lungs Peal M., Josephson M., Handschin B., Brown D. Univ Minnesota, Sch Med, Dept Lab Med 6 Pathol, Minneapolis, Mn 55455, USA PROSTAGLAND LEUK MRD 1983, 11, (2) 171 The effect of prenatal dexamethasone on fetal rat lung prostaglandin synthesis Boissonneault G.A.. Johnston P.W.* *Uaiv Illinois, Dept Food Sci, Urbana, I1 61801, USA J NUTR 1983, 113 (3) 1187 Essential fatty acid deficiency, prostaglandin synthesis and humoral immunity in Lewis rats Grotemeyer K.H., Viand R. Univ Essen Gesaothsch, Neural Klin &

Poliklin, D-4300 Essen 1, W Germany VASA-J VASC DIS 1983, 12 (2) 126 Methodical aspects regarding the collagen-induced prostaglandin synthesis of platelets EFFECTS Capasso,F., Mascolo, N., Autore, G.,

Duraccio, M.R. Unlv Naples, Sch Pharm, Inst Exptl Pharmacol. I-80138 Naples, Italy J PSARM PRARHACOL 1983, 35 (5) 332 Glycyrrhetinic acid, leucocytes and prostaglandins

rrocha,

Catravas, G.N. Armed Forces Radiobiol Res Inst, Dept Biochem, Bethesda, +td 20814, USA RADIAT RES 1983, 96 (L) 239 Effect of radioprotectaot WK 2711 on cyclic nocleotides, prostaglandins, and lysosomes P.J.,

Rubin, L.J., Lazar, J.D. Vet Adm Med Ctr, Dept Med, Dallas, TX 75216, USA J CLIN INVEST 1983, 2 (5) 1366 Nonadrenergic effects of isoproterenol in dogs with hypoxic pulmonary vasoconstriction - t possible role of prostaglandins Kosher, R.A., Walker, K.H. Univ Connecticut, Ctr Hlth, Dept Anat, Farmington, Ct 06032, USA EXP CELL KES 1983, 145 (1) 145 The effect of prostzandins on in vitro limb cartilage differentiation Davis D.L., Pakrasi P.L., Dey S.K. Kansas State Univ, Agr h Appl Sci, Dept Anim Sci & Ind, Manhattan, Ks 66506, USA BIOL B&PROD 1983, (1 (5) 1114 Prostaglandins in swine blastocysts

&i-till, J.O., dyers, L.W., I;lllsoil, b.W. Addcess as above J NEUKOIMMUNUL 1983, u (3) SJY-251 Regulation of natural-killer cell cytotoxicity by prostaglandin 0 in the peripheral blood and cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases. Part 2 (Effect of exogenous PGEl on spontaneous and interferoninduced natural killer) PROSTAGLANDINS IN MEDICINE Levine S.D. Yeshiva Univ Albert Einstein Co11 Med, Bronx, NY 10461, USA HEPATOLOGY 1983, 3 (3) 457 Renal prostaglandins in cirrhosis (Editorial) Nieder, J., Augustin, W. Med Akad Magdeburg, Landesfrauelllclin, Gerhart Hauptmann Str 35, DDH-3060 Magdeburg, E Germany ZtlLGYlYAKOL 1983, 105 (7) 411 Concentrations of primary prostaglandlns in amniotic fluid, maternal venous blood and umbilical cord blood during spontaneous deliveries at term

Nicolaides, K.H., Koullapis, E.N., Kodeck, C.H.* Rink, T.J., Smith, S.W. *Kings Co11 Hosp Med Sch, Dept Ubstet Univ Cambridge. Phvsiol Lab. Cambridge& Gynaecol, London SE!I8RX, England CB2 3EG, England . PRENATAL DIAG 1983, _' (2) 97 J PHYSIUL LONDON 1983, 33&l 66P The safety of fetoscopy: (II). Effect Inhibitory prostaglandinssuppress on maternal plasma levels of 13,14CaZ+ influx, the release of intradihydro-L5-oxo-prostaglandin FZalpha cellular Ca2f and the responsiveness to cytoplasmic Ca2+ in human Katayama H., Kawada A., Endoh C., platelets (Abstract) Hori H., Yoshikawa K. Jichi Med Sch, Dept Dermatol, Minami Gee, M.H., Perkowski, S.Z., Havill, kawachi, Tochigi 32904, Japan A.l+l.,Flynn, J.T. ACTA DERNATO-VENEREOL 1983, fi (3) Thomas Jefferson Univ, Jefferson i.ied 233 Coil, Dept Physiol, Phzladelphia, Pa Reduced excretion of the main urinary 19107, USA metabolite of prostaglandin Flalpha CHEST 1983, 3 (5) (Suppl) 82s and F2alpha in psoriatic patients Role of prostaglandins and leukotrienes in complement-initiated lung Fole, D.F. vascular injury Univ London, Inst Ophthalmol, London, Shimada H., Okamura H., Noda Y., Suzuki A., Tojo S., Takada A. Kyoto Univ, Fat Med, Dept Gynecol h Obstet, Sakyo ku, Kyoto 606, Japan J ENDOCRINOL 1983, 97 (L) 201 Plasminogen activator in rat ovary during the ovulatory process Independence of prostaglandin mediation Merrill, J.E., Gerner, R.H., Myers, L.W., Ellison, G.ui. Univ Calif Los Angeles, Reed Neural, Res Ctr, Dept Neural, Los Angeles, Ca 90024, USA J NEUROINMLINOL 1983, 4 (3) 223-237 Regulation of natural killer cell cytotoxicity by prostaglandin E in the peripheral blood and cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases, Part 1 (association between amount of prostaglandin produced, natural killer, and endogenous interferon)

England J INT BIOMEI) INF DATA lY83, 5 (1) 11 Prostaglandins and other agonists in the injury response of the eye Brigham, K.L., Ogletree, rl., Snapper, J., Hinson, J., Parker, P. Vanderbilt Univ, Med Ctr N, Nashville, Tn 37235, USA 70s CHEST 1983, g (5) (s~ppl) Prostaglandins and lung injury Beckon, J. Brookman Clin, POB 16336, Jerusalem, Israel ACTA HAENATOL 1983, 69 (6) 419 Coagulation inhibition in manic depression: Relevance of prostaglandins (Letter) Rao G., Reddy K., White J. Univ tlonn, Inst Klin Biochem, 1)-53OU Bonn 1, W Germany PRUSTAGLA& LEUK MEI, 1983, & (L) 1YY Penicillin induced human platelet dysfunction and its reversal by epinephrine

INHIBITORS

OF sms1s

Lintoo. T., Dickson, G.R. Belfast City Hosp. Dept Clin Che% Belfast BT9 TAD, Antrim, IIIreland IRCS PIEDSCI-BIOMBM 1983, G(5) 404 The effect of flurbiprofen on the formation of prootaglandin E (El and ~2) and prostaglandia F2alphr during fracture repair in the rat Adcock, J.E., Hernandee, DE., Ncmsroff, C.B., Prong+, A.J. Univ N Carolina, Sch Xed Biol Sci Res Ctr, Chapel Hill, NC 27514, USA LIFE SC1 1983, 21 (25) 2905 gffect of prortaglandin synthesis inhibitors on neurotensin and sodium salicylate-induced gastric cytoprotection In rats Levy-Toledano, S., Maclouf, J., Caen, J., Bara, L.. Lecrubier, C., Samma, M. Bop Lariboisierc, INSBRM, U150, F-75475 Paris 10, France J PBARMACOL 1983, 14 (2) 141 Effect of flurbfprofen on platelet functions. Relationship with the platelet thromboxane synthesis and the prostacyclin production by the rabbit aorta Shibuya, M., Ebiauka, Y., Noguchi, H., Iitaka. Y., Sankawa. II.* funiv Tokyo, Pat Pharmaceut Sci, Bunkyo Ku, Tokyo 113. Japan CHEM PHARM BULL TOKYO 1983, 31 (2) 407 Inhibition of prostaglandin biosynthesis by 4-O-methylcryptochlorophaeic acid: synthesis of monomeric arylcarboxylic acids for inhibitory activity testing and X-ray analysis of 4-O-methylcryptochlorophaeic acid Y., Noguchi, Xln-Sheng, Y., Ebizoka, Kiuchi, F., Iitaka, Y., Sankawa, u.*, Seto, H. *Univ Tokyo, Fat Pharmaceut Sci, Bunkyo Ku, Tokyo 113, Japan TETRAHFDRON LETT 1983, g (23) 2407 Structure of arnebinol, a new awn-type monoterpenylbenzenoidwith inhibitory effect to prostaglandln biosynthesis il..

Huland, H., Gonnermann. D., LeichtWeiss. H.P. Univ Hamburg, Urol Klin 6 Poliklin, D-2000 Hamburg 20, W Germany AKT UROL 1983, 14 (3) 109 Reversibility of preglomerular active vasoconstriction in hypernephrotic kidneys by prostaglandin synthesis inhibition - the physiologic basis for a clinical test to predict improvement of renal function in hydronephrosie (German) Louie S., Gurewlch V. Tufts Univ. St Elizabeth6 Hosp. Sch Med. Dept Med, Vast Lab, Boston, Ma 02135, USA THF.OMBRES 1983, g (4) 323 The antithrombotic effect of aspirin and dipyridamole in relation to prostaglandin synthesis

de Kergommeaux B., Ali H., McDonald J.* *Univ Western Ontario, Dept Med, London, Ontario, Canada MA 5A5 PROSTAGLAND LBUK MgD 1983, 11 (2) 225 Effects of ASA on thromborane and proetacyclin synthesis by rabbit aorta and pulmonary artery

Indomthacin Kirkpatrick, C.J., Nohr, W., Haferkamp, 0. Univ Ulm, Dept Pathol. D-7900 Ulm, W Germany

FxP CELL BIOL 1983, 51 (4) 192 Effects of prostanoidprecursors and indomethacln on chick embryonic cartilage growth in organ culture

O-Yang, C.P., Fried, J.* *Jniv Chicago, Dept Chem, Chicago, I1 60637, USA TETRAI&DYL)NLHTT 1983, fi (25) 2533 Separation of acetylaaic proetaglandin isomers as cobalt coapleres Nishchcnko, T.Y., Korotchenko, O.D., Isai, S.V. Acad Sci USSR, Far E Sci Ctr, Pacific Bioorgan Chem Inst. Vladivostok, USSR BULL EXP BIOL MgD BNGL TR 1982, z (11) 1583 Search for prostaglandin-like substances in marine organisms EECBNIyUES Yamada K., Onodera M., Aiaawa Y. Tokyo Co11 Pharr, Dcpt Pharmacol, Hachioji, Tokyo 19203, Japan J PBARMACOL HETli1983. 2 (2) Y3 Determination of prostaglandin El and the main prostaglaadin E metabolite by micro high-performance liquid chromatography using fluorescence derivatieation with dansyl hydrazine

Boyd, L.M., Ezra, D., Peuerstein, G., Goldstein. R.E.* *Uniformed Serv Unlv Hlth Sci, Dept Med. Div Cardfol. Bethesda, Md 208i4, USA FUR J PHARMACOL 1983, g (3-4) 307 Effects of PPL-55712 or indomethacin Demurs, L.M., Brennecke, S.P., on leukotriene-inducedcoronary Mountford, L.A., Brunt, J.D., Turnbull, constriction in the intact pig heart A.C. Penn State Univ. Milton S Hershey Ned Moron I-'., Javor T., Bata M., Fiegler Ctr, Dept Pathol, Hershey, Pa 17033, M., Uossik G.* USA *Univ Pets, Sch Med. Dept Med 1, J CLIN ENDOCRINOL METAB 1983. II. (1) H-7643 Pets, Hungary 101 ACTA PHYSIOL ACAO SC1 HUNG 1982, 60 Development and validation of a (3) 149 The relationships between indometha- radioimmunoassay for prostaglandin E2 metabolite levels in plasma tin-Induced gastric ulcer, ulcer protection by cimetidine and prostaAlekseev, S.M., Konkin, E.E., Sarycheva, cyclin and the cAMP system of the I.K., Pomoinetsky, V.D., Zolotukhin, gastric fundic mucosa in the rat S.V., Evstigneeva, R.P. NV Lomonosov Fine Chem Technol Lnst, ANAJ.OGUES.ANL) CHEMICAL SYNTHESIS Moscow, USSR Bradbury, R.H., Walker, K.A.M.* KHIM FARM Zd 1983, z (5) 619 *Syntax Res Carp, Inst Organ Chem, 4-Bromomethyl-I,f+ben+ocoumarine- a Palo Alto, Ca 94304, USA reagent for quantitative fluorimetrlc J ORG CHEM 1983, 48 (10) 1741 analysis of fatty acids and prostaSynthesis of analogues of prostaglandins cyclin containing a thiazole ring Rosenberger, M., Newkom, C., Aig, E.R. Hoffmann La Roche Inc, Div Res 6 Dev, Nutley, NJ 07110, USA J APIERCHEH SOC 1983, 105 (11) 3656 Total synthesis of leu=riene E4, a member of the SRS-A family Cohen, N., Banner, B.L., Lopresti, R.J., Wang, F., Rosenberger. M., Liu, Y.Y., Thorn,E., Liebnan, A.A. Hoffmann La Roche Inc, Div Res 6 Oev, Nutley, NJ 07110, USA J AMF.RCHEM SOC 1983, 105 (11) 3661 Enanriospecific syntheses of leukotrienes C4, ~4, and E4 and (14,153HZ)leukotriene E4 dimethyl ester Hamanaka, N., Toda, M., Takaoka, S., Hayashi, M., Iwashita, T. Ono Pharmaceut Co Ltd, Pes Inst. Mishima, Osaka 618, Japan CHEM PHARM BULL TOKYO 1983, c (2) 557 The structures of 15-dehydroprostaglandin Bl dimers