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Occurrence of Oral Squamous Cell Carcinoma in a Young Patient: Case Report
OOOO Volume 117, Number 2 GERMANO, GIORDANO BRUNO PAIVA CAMPOS, ANA MIRYAM COSTA DE MEDEIROS, MÁRCIA CRISTINA DA COSTA MIGUEL. UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE. Necrotizing sialometaplasia is a benign, self-limiting inflammatory condition first described in 1973. Its clinical and histologic features mimic those of a malignant neoplasm, mainly mucoepidermoid carcinoma or squamous cell carcinoma. A case description focused on histologic stage and histopathogenesis of the lesion. Man, 26, presented an ulcerated mass in the soft palate. The lesion had appeared 40 days previously and was reddish, firm, and painless, measuring 0.5 cm in diameter. No secondary signals or lymphadenopathy was present. The clinical diagnosis was traumatic ulcer. Histopathological examination revealed scarce necrosis of the glandular acini, squamous metaplasia of the salivary ductal epithelium, pseudoepitheliomatous hyperplasia of the overlying epithelium, and an associated inflammatory response. This case demonstrates principally the reparative histological stage proposed by Anneroth and Hasen (1982): metaplastic change of ducts, fibrosis, and chronic inflammatory infiltrate. Pathophysiology of this lesion is related to ischemic events. Its accurate recognition avoids inappropriate treatment.
PE-223 - NEUROFIBROMA IN THE TONGUE: CASE REPORT. JOSÉ NARCISO ROSA ASSUNÇÃO JUNIOR, JOSÉ NARCISO ROSA ASSUNÇÃO JUNIOR, JORGE DE SÁ BARBOSA, HAROLDO ARID SOARES, NELISE ALEXANDRE DA SILVA LASCANE, DECIO DOS SANTOS PINTO JUNIOR, CELSO AUGUSTO LEMOS JUNIOR. UNIVERSIDADE METROPOLITANA DE SANTOS/FACULDADE DE ODONTOLOGIA DA USP. Caucasian woman, 64, demonstrated a tongue lesion that had developed over 8 months. She reported local trauma with asymptomatic slow growth of a nodule. Intraoral examination showed an encapsulated submucosal nodule, measuring 1 cm in diameter, which was asymptomatic on palpation; the surface mucosa was reddish and smooth. The clinical diagnosis was neuroma X lipoma. After the excisional biopsy, histological examination revealed a mucosal fragment lined by stratified squamous epithelium and a parakeratinized area of dense connective tissue showing thick bundles of collagen fibers distributed parallel to the epithelium, with a proliferation of bundles of spindle cells in various directions, often with corrugated nuclei. There were also various stromal cells with eosinophilic cytoplasm resembling mast cells. The result suggested neurofibroma. The patient remains asymptomatic with no signs of recurrence after 1 year of follow-up.
PE-224 - NON-FAMILIAL CHERUBISM ASSOCIATED WITH CONGENITAL CARDIOPATHY: DIFFERENTIAL DIAGNOSIS WITH NOONAN SYNDROME AND TURNER SYNDROME. ARTHUR PIAS SALGUEIRO, RONAIRO ZAIOSC TURCHIELLO, MICHELE RORATO SAGRILLO, MÁRCIA RODRIGUES PAYERAS, LEANDRO BERNI OSÓRIO, KÍVIA LINHARES FERRAZZO. FRANCISCAN UNIVERSITY CENTER - UNIFRA - SANTA MARIA/ RS, BRAZIL. Cherubism is a rare disease that usually manifests in childhood. A case of cherubism was reported and the clinical, radiographic, and laboratory findings noted, focusing on the differential diagnosis. Girl, 10, was brought for dental care with a medical history of pulmonary valve stenosis, short stature, and bilateral convergent strabismus. Physical examination, imaging
ABSTRACTS Abstracts e175 findings, laboratory tests, and histology suggested the diagnosis of cherubism. Given the heart disease, a differential diagnosis of cherubism with Noonan syndrome (NS) and Turner syndrome (TS) was postulated. After normal cytogenetic examination, TS was ruled out. Based on the clinical diagnostic criteria proposed by Van der Burgt et al (1994), the diagnosis of NS was not possible. For the differential diagnosis of cherubism, it is necessary to unite medical history, physical evaluation, radiographic findings, and laboratory tests. Although clinical criteria are useful in the diagnosis of NS, genetic tests are essential to establish the definitive diagnosis of this disease.
PE-225 - NON-HODGKIN’S LYMPHOMA IN THE SUBMANDIBULAR REGION. LEONARDO AMARAL DOS REIS, ALÍCIA RUMAYOR PIÑA, MARISOL MARTINEZ MARTINEZ, NÁDIA LAGES LIMA, JOÃO LUIZ DE MIRANDA, OSLEI PAES DE ALMEIDA, ANA TEREZINHA MARQUES MESQUITA. UNIVERSIDADE FEDERAL DOS VALES DO JEQUITINHONHA E MUCURI. The diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin’s lymphoma and is more frequent in the head and neck region. Man, 58, had swelling in the right submandibular region that had developed over 4 months. His medical history was uneventful. Extraoral examination revealed a nodular lesion, normal in color, with ill-defined borders, that was adhering to the underlying tissues. Intraoral examination and panoramic radiograph showed normal features. Histopathological analysis revealed malignancy of lymphocytic origin and demonstrated cells of varied morphologies, some large cells with polymorphic nuclei, and atypical mitosis. Immunohistochemical analysis showed the atypical cells were positive for LCA, CD20, CD43, CD45RO, and CD79a, but negative for CD3, CD138, kappa, and lambda. Ki-67 proliferation index was 60%. The definitive diagnosis was diffuse large B-cell lymphoma. The patient was referred for treatment and is under follow-up.
PE-226 - NOONAN SYNDROME AND ITS DENTOFACIAL ACCOMPANIMENTS: REPORT OF TWO CLINICAL CASES. CAROLINE FARIAS LEMOS, LUCIANA DUARTE CALDAS, BERNARDO FERREIRA BRASILEIRO, MARTA RABELLO PIVA. UNIVERSIDADE FEDERAL DE SERGIPE. Noonan syndrome (NS) is an autosomal dominant genetic syndrome that affects both genders, with an incidence estimated between 1:1000 and 1:2500. NS is an important differential diagnosis in patients with short stature, facial dysmorphism, delayed puberty, and cryptorchidism. Among the facial changes typical of NS carriers are hypertelorism of the eye, eyelid ptosis, palpebral fissure externally diverted down with low attachment, incomplete rotation of the ear, mandibular micrognathia, short and webbed neck, and a triangularly shaped face. Changes produced include dental maxillary atresia, making an adequate tongue position and triggering, usually a posterior cross-bite and eventually an anterior open bite. By virtue of mandibular micrognathia, such patients have malocclusions of type Class II malocclusion. Two patients with NS demonstrated similarities in dentofacial changes and the therapeutic procedures employed.
PE-227 - OCCURRENCE OF ORAL SQUAMOUS CELL CARCINOMA IN A YOUNG PATIENT: CASE REPORT. MATEUS BARROS CAVALCANTE, CAMILA MARIA BEDER RIBEIRO, SONIA MARIA SOARES
ORAL AND MAXILLOFACIAL PATHOLOGY e176 Abstracts FERREIRA, DARLLY JANNE ALVES DE AZEVEDO, BÁRBARA DE MORAES RAMOS ROCHA, MARCOS VINICIUS VASCONCELOS FEITOSA BORGES, EVELLYNE PEREIRA CAVALCANTE. CENTRO UNIVERSITÁRIO CESMAC. Oral squamous cell carcinoma (OSCC) is an invasive malignant neoplasm of epithelial origin. Clinically, it may take different aspects in its early stages and show areas of leukoplakia, erythroplasia, erythroleukoplakia, or ulceration that do not heal. White man, 35, was referred to the dental clinic in a college in Northeastern Brazil with painful symptoms and an irregular ulcerated lesion present for 3 months. The incisional biopsy specimen was sent for anatomopathological analysis, which revealed fragments of malignant neoplasm, islands of neoplastic cells that had invaded and destroyed the connective tissue, nuclear and cell pleomorphism, atypical mitosis, and chronic inflammatory infiltrate. This malignancy seldom occurs in patients under age 40 years. The case highlights the importance of diagnosing oral cancer lesions early and conducting prevention campaigns for young patients, although it is more common to see these lesions in people over age 50 years.
PE-228 - ODONTOGENIC CYST ORTHOKERATINIZED IN ELDERLY WOMAN. JARIELLE OLIVEIRA MASCARENHAS ANDRADE, JOANA DOURADO MARTINS, MARCO ANTONIO ALVES DA SILVA, MARIA DA CONCEIÇÃO ANDRADE, VALÉRIA SOUZA FREITAS, MÁRCIO CAMPOS OLIVEIRA. UNIVERSIDADE ESTADUAL DE FEIRA DE SANTANA. Odontogenic cyst orthokeratinized refers to an odontogenic cyst that has a microscopically orthokeratinized epithelial border. Dark-skinned woman, 88, came to the stomatology clinic complaining of pain in tooth #4.1. After evaluating panoramic radiographs, we observed the presence of extensive radiolucent defined edges, a diagnosis suggestive of odontogenic cyst. Aspiration biopsy found yellow liquid. Surgical enucleation and histopathological analysis revealed a diagnosis of odontogenic cyst orthokeratinized. The patient has been under clinical and radiographic observation for 14 months with no signs of recurrence. In the past, odontogenic cyst orthokeratinized was considered a variant of odontogenic keratocyst. However, its clinical behavior is far more indolent when that of the latter, allowing its reclassification as a distinct injury. Its occurrence in the anterior jaw of elderly women has differed significantly in epidemiological patterns according to the literature.
PE-229 - ODONTOGENIC MYXOMA IN ELDERLY PATIENT. HELITON GUSTAVO DE LIMA, INGRID ARAÚJO DE OLIVEIRA SOUZA, KAREN HENRIETTE PINKE, IZABEL REGINA FISCHER RUBIRA-BULLEN, JOSÉ HUMBERTO DAMANTE, VANESSA SOARES LARA. BAURU SCHOOL OF DENTISTRY, UNIVERSITY OF SAO PAULO. Odontogenic myxomas (OMs) are predominantly found in young adults. This case report provides clinical and microscopic information about an unusual OM in an elderly patient. Woman, 80, had swelling between the upper right canine and premolar. She reported that in the same region 3 years previously a biopsy was performed that prompted a microscopic diagnosis of hyperplasia. Intraoral examination revealed a single, sessile, firm, wellcircumscribed lesion, no alteration in color, and no symptoms. Periapical radiography showed thickening of the periodontal
OOOO February 2014 ligament. The presumptive diagnosis was chronic inflammatory lesion. During the excisional biopsy, observations included loss of vestibular cortical bone; the specimen presented gelatinous features. Microscopic examination revealed myxomatous tissue sometimes filling the marrow spaces of trabecular bone. Within myxomatosis areas were seen stellate or spindle cells and a few islands of odontogenic epithelium. The definitive diagnosis was OM. The patient is being followed up with no recurrence.
PE-230 - ODONTOGENIC MYXOMA IN ANTERIOR REGION OF THE MANDIBLE: CASE REPORT. MARCOS VINÍCIUS DE VASCONCELOS FEITOSA BORGES, JOSÉ RICARDO MIKAMI, CAMILA MARIA BEDER RIBEIRO, CAMILA DE QUEIROZ TORRES BARROS, JÉSSYCA ÍTALA BARROS WANDERLEY DA SILVA, EVELLYNE PEREIRA CAVALCANTE, MATEUS BARROS CAVALCANTE. CENTRO UNIVERSITÁRIO CESMAC. Odontogenic myxoma (OM) is a mesenchymal lesion that originates in the dental papilla and the dental follicle. It affects patients whose average age is 30 years but shows no predilection for either gender. Any area of the gnathic bones can be involved, with a predilection for the jaw. Dark-skinned young man, 16, came in September 2006 complaining of a painless lesion in the lower incisor with pain and bleeding. The initial biopsy led to a histopathological diagnosis of focal oral mucinosis. The patient returned in 2007 and a new biopsy confirmed the diagnosis of OM. On histological analysis the typical appearance of OM was seen, with randomly oriented stellate, spindle-shaped, and round cells with long cytoplasmic processes. After surgical curettage the patient remained free of recurrence for 4 years. The importance of this case is the reported relapse after conservative treatment and recognizing the value of radical treatment for such cases.
PE-231 - ODONTOGENIC MYXOMA: CASE REPORT. TABATA DE MELLO TERA, RODRIGO DIAS NASCIMENTO, RENATA FALCHETE DO PRADO, ADRIANA DA MOTA DELGADO, MIRIANE CARNEIRO MACHADO, MARIA APARECIDA NEVES JARDINI, YASMIN RODARTE CARVALHO. FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS - UNIVERSIDADE ESTADUAL PAULISTA. FOSJC/UNESP. Odontogenic myxoma is a rare ectomesenchymal tumor comprising 3% to 6% of all odontogenic tumors. It occurs mostly in the second or third decades of life and affects mainly the posterior mandible. The tumor displays slow growth and may displace teeth and lead to the expansion of bone. Radiographically, it appears as a unilocular or multilocular radiolucency with irregular margins. Multilocular lesions may present a “racket” appearance, with the trabeculae of residual bone arranged at right angles to one another. Case Report: Dark-skinned young man, 15, presented a radiolucent lesion between teeth #37 and #38, with displacement of the latter. Surgical removal was performed; after 6 years, the patient had a recurrence. Microscopically there were stellate cells in an abundant myxoid stroma, yielding a diagnosis of odontogenic myxoma. Immunohistochemical examination showed positive reactions for smooth muscle actin, vimentin, and Ki-67. The treatment was surgical resection with a safety margin.
PE-232 - ODONTOGENIC MYXOMA: CLINICOPATHOLOGICAL ANALYSIS OF A CASE REPORT. SABRINA POZATTI MOURE, JOSÉ RICARDO SOUSA COSTA, EMERSON FERREIRA HONÓRIO, MILENE CASTILHOS
PE-223 - NEUROFIBROMA IN THE TONGUE: CASE REPORT. JOSÉ NARCISO ROSA ASSUNÇÃO JUNIOR, JOSÉ NARCISO ROSA ASSUNÇÃO JUNIOR, JORGE DE SÁ BARBOSA, HAROLDO ARID SOARES, NELISE ALEXANDRE DA SILVA LASCANE, DECIO DOS SANTOS PINTO JUNIOR, CELSO AUGUSTO LEMOS JUNIOR. UNIVERSIDADE METROPOLITANA DE SANTOS/FACULDADE DE ODONTOLOGIA DA USP. Caucasian woman, 64, demonstrated a tongue lesion that had developed over 8 months. She reported local trauma with asymptomatic slow growth of a nodule. Intraoral examination showed an encapsulated submucosal nodule, measuring 1 cm in diameter, which was asymptomatic on palpation; the surface mucosa was reddish and smooth. The clinical diagnosis was neuroma X lipoma. After the excisional biopsy, histological examination revealed a mucosal fragment lined by stratified squamous epithelium and a parakeratinized area of dense connective tissue showing thick bundles of collagen fibers distributed parallel to the epithelium, with a proliferation of bundles of spindle cells in various directions, often with corrugated nuclei. There were also various stromal cells with eosinophilic cytoplasm resembling mast cells. The result suggested neurofibroma. The patient remains asymptomatic with no signs of recurrence after 1 year of follow-up.
PE-224 - NON-FAMILIAL CHERUBISM ASSOCIATED WITH CONGENITAL CARDIOPATHY: DIFFERENTIAL DIAGNOSIS WITH NOONAN SYNDROME AND TURNER SYNDROME. ARTHUR PIAS SALGUEIRO, RONAIRO ZAIOSC TURCHIELLO, MICHELE RORATO SAGRILLO, MÁRCIA RODRIGUES PAYERAS, LEANDRO BERNI OSÓRIO, KÍVIA LINHARES FERRAZZO. FRANCISCAN UNIVERSITY CENTER - UNIFRA - SANTA MARIA/ RS, BRAZIL. Cherubism is a rare disease that usually manifests in childhood. A case of cherubism was reported and the clinical, radiographic, and laboratory findings noted, focusing on the differential diagnosis. Girl, 10, was brought for dental care with a medical history of pulmonary valve stenosis, short stature, and bilateral convergent strabismus. Physical examination, imaging
ABSTRACTS Abstracts e175 findings, laboratory tests, and histology suggested the diagnosis of cherubism. Given the heart disease, a differential diagnosis of cherubism with Noonan syndrome (NS) and Turner syndrome (TS) was postulated. After normal cytogenetic examination, TS was ruled out. Based on the clinical diagnostic criteria proposed by Van der Burgt et al (1994), the diagnosis of NS was not possible. For the differential diagnosis of cherubism, it is necessary to unite medical history, physical evaluation, radiographic findings, and laboratory tests. Although clinical criteria are useful in the diagnosis of NS, genetic tests are essential to establish the definitive diagnosis of this disease.
PE-225 - NON-HODGKIN’S LYMPHOMA IN THE SUBMANDIBULAR REGION. LEONARDO AMARAL DOS REIS, ALÍCIA RUMAYOR PIÑA, MARISOL MARTINEZ MARTINEZ, NÁDIA LAGES LIMA, JOÃO LUIZ DE MIRANDA, OSLEI PAES DE ALMEIDA, ANA TEREZINHA MARQUES MESQUITA. UNIVERSIDADE FEDERAL DOS VALES DO JEQUITINHONHA E MUCURI. The diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin’s lymphoma and is more frequent in the head and neck region. Man, 58, had swelling in the right submandibular region that had developed over 4 months. His medical history was uneventful. Extraoral examination revealed a nodular lesion, normal in color, with ill-defined borders, that was adhering to the underlying tissues. Intraoral examination and panoramic radiograph showed normal features. Histopathological analysis revealed malignancy of lymphocytic origin and demonstrated cells of varied morphologies, some large cells with polymorphic nuclei, and atypical mitosis. Immunohistochemical analysis showed the atypical cells were positive for LCA, CD20, CD43, CD45RO, and CD79a, but negative for CD3, CD138, kappa, and lambda. Ki-67 proliferation index was 60%. The definitive diagnosis was diffuse large B-cell lymphoma. The patient was referred for treatment and is under follow-up.
PE-226 - NOONAN SYNDROME AND ITS DENTOFACIAL ACCOMPANIMENTS: REPORT OF TWO CLINICAL CASES. CAROLINE FARIAS LEMOS, LUCIANA DUARTE CALDAS, BERNARDO FERREIRA BRASILEIRO, MARTA RABELLO PIVA. UNIVERSIDADE FEDERAL DE SERGIPE. Noonan syndrome (NS) is an autosomal dominant genetic syndrome that affects both genders, with an incidence estimated between 1:1000 and 1:2500. NS is an important differential diagnosis in patients with short stature, facial dysmorphism, delayed puberty, and cryptorchidism. Among the facial changes typical of NS carriers are hypertelorism of the eye, eyelid ptosis, palpebral fissure externally diverted down with low attachment, incomplete rotation of the ear, mandibular micrognathia, short and webbed neck, and a triangularly shaped face. Changes produced include dental maxillary atresia, making an adequate tongue position and triggering, usually a posterior cross-bite and eventually an anterior open bite. By virtue of mandibular micrognathia, such patients have malocclusions of type Class II malocclusion. Two patients with NS demonstrated similarities in dentofacial changes and the therapeutic procedures employed.
PE-227 - OCCURRENCE OF ORAL SQUAMOUS CELL CARCINOMA IN A YOUNG PATIENT: CASE REPORT. MATEUS BARROS CAVALCANTE, CAMILA MARIA BEDER RIBEIRO, SONIA MARIA SOARES
ORAL AND MAXILLOFACIAL PATHOLOGY e176 Abstracts FERREIRA, DARLLY JANNE ALVES DE AZEVEDO, BÁRBARA DE MORAES RAMOS ROCHA, MARCOS VINICIUS VASCONCELOS FEITOSA BORGES, EVELLYNE PEREIRA CAVALCANTE. CENTRO UNIVERSITÁRIO CESMAC. Oral squamous cell carcinoma (OSCC) is an invasive malignant neoplasm of epithelial origin. Clinically, it may take different aspects in its early stages and show areas of leukoplakia, erythroplasia, erythroleukoplakia, or ulceration that do not heal. White man, 35, was referred to the dental clinic in a college in Northeastern Brazil with painful symptoms and an irregular ulcerated lesion present for 3 months. The incisional biopsy specimen was sent for anatomopathological analysis, which revealed fragments of malignant neoplasm, islands of neoplastic cells that had invaded and destroyed the connective tissue, nuclear and cell pleomorphism, atypical mitosis, and chronic inflammatory infiltrate. This malignancy seldom occurs in patients under age 40 years. The case highlights the importance of diagnosing oral cancer lesions early and conducting prevention campaigns for young patients, although it is more common to see these lesions in people over age 50 years.
PE-228 - ODONTOGENIC CYST ORTHOKERATINIZED IN ELDERLY WOMAN. JARIELLE OLIVEIRA MASCARENHAS ANDRADE, JOANA DOURADO MARTINS, MARCO ANTONIO ALVES DA SILVA, MARIA DA CONCEIÇÃO ANDRADE, VALÉRIA SOUZA FREITAS, MÁRCIO CAMPOS OLIVEIRA. UNIVERSIDADE ESTADUAL DE FEIRA DE SANTANA. Odontogenic cyst orthokeratinized refers to an odontogenic cyst that has a microscopically orthokeratinized epithelial border. Dark-skinned woman, 88, came to the stomatology clinic complaining of pain in tooth #4.1. After evaluating panoramic radiographs, we observed the presence of extensive radiolucent defined edges, a diagnosis suggestive of odontogenic cyst. Aspiration biopsy found yellow liquid. Surgical enucleation and histopathological analysis revealed a diagnosis of odontogenic cyst orthokeratinized. The patient has been under clinical and radiographic observation for 14 months with no signs of recurrence. In the past, odontogenic cyst orthokeratinized was considered a variant of odontogenic keratocyst. However, its clinical behavior is far more indolent when that of the latter, allowing its reclassification as a distinct injury. Its occurrence in the anterior jaw of elderly women has differed significantly in epidemiological patterns according to the literature.
PE-229 - ODONTOGENIC MYXOMA IN ELDERLY PATIENT. HELITON GUSTAVO DE LIMA, INGRID ARAÚJO DE OLIVEIRA SOUZA, KAREN HENRIETTE PINKE, IZABEL REGINA FISCHER RUBIRA-BULLEN, JOSÉ HUMBERTO DAMANTE, VANESSA SOARES LARA. BAURU SCHOOL OF DENTISTRY, UNIVERSITY OF SAO PAULO. Odontogenic myxomas (OMs) are predominantly found in young adults. This case report provides clinical and microscopic information about an unusual OM in an elderly patient. Woman, 80, had swelling between the upper right canine and premolar. She reported that in the same region 3 years previously a biopsy was performed that prompted a microscopic diagnosis of hyperplasia. Intraoral examination revealed a single, sessile, firm, wellcircumscribed lesion, no alteration in color, and no symptoms. Periapical radiography showed thickening of the periodontal
OOOO February 2014 ligament. The presumptive diagnosis was chronic inflammatory lesion. During the excisional biopsy, observations included loss of vestibular cortical bone; the specimen presented gelatinous features. Microscopic examination revealed myxomatous tissue sometimes filling the marrow spaces of trabecular bone. Within myxomatosis areas were seen stellate or spindle cells and a few islands of odontogenic epithelium. The definitive diagnosis was OM. The patient is being followed up with no recurrence.
PE-230 - ODONTOGENIC MYXOMA IN ANTERIOR REGION OF THE MANDIBLE: CASE REPORT. MARCOS VINÍCIUS DE VASCONCELOS FEITOSA BORGES, JOSÉ RICARDO MIKAMI, CAMILA MARIA BEDER RIBEIRO, CAMILA DE QUEIROZ TORRES BARROS, JÉSSYCA ÍTALA BARROS WANDERLEY DA SILVA, EVELLYNE PEREIRA CAVALCANTE, MATEUS BARROS CAVALCANTE. CENTRO UNIVERSITÁRIO CESMAC. Odontogenic myxoma (OM) is a mesenchymal lesion that originates in the dental papilla and the dental follicle. It affects patients whose average age is 30 years but shows no predilection for either gender. Any area of the gnathic bones can be involved, with a predilection for the jaw. Dark-skinned young man, 16, came in September 2006 complaining of a painless lesion in the lower incisor with pain and bleeding. The initial biopsy led to a histopathological diagnosis of focal oral mucinosis. The patient returned in 2007 and a new biopsy confirmed the diagnosis of OM. On histological analysis the typical appearance of OM was seen, with randomly oriented stellate, spindle-shaped, and round cells with long cytoplasmic processes. After surgical curettage the patient remained free of recurrence for 4 years. The importance of this case is the reported relapse after conservative treatment and recognizing the value of radical treatment for such cases.
PE-231 - ODONTOGENIC MYXOMA: CASE REPORT. TABATA DE MELLO TERA, RODRIGO DIAS NASCIMENTO, RENATA FALCHETE DO PRADO, ADRIANA DA MOTA DELGADO, MIRIANE CARNEIRO MACHADO, MARIA APARECIDA NEVES JARDINI, YASMIN RODARTE CARVALHO. FACULDADE DE ODONTOLOGIA DE SÃO JOSÉ DOS CAMPOS - UNIVERSIDADE ESTADUAL PAULISTA. FOSJC/UNESP. Odontogenic myxoma is a rare ectomesenchymal tumor comprising 3% to 6% of all odontogenic tumors. It occurs mostly in the second or third decades of life and affects mainly the posterior mandible. The tumor displays slow growth and may displace teeth and lead to the expansion of bone. Radiographically, it appears as a unilocular or multilocular radiolucency with irregular margins. Multilocular lesions may present a “racket” appearance, with the trabeculae of residual bone arranged at right angles to one another. Case Report: Dark-skinned young man, 15, presented a radiolucent lesion between teeth #37 and #38, with displacement of the latter. Surgical removal was performed; after 6 years, the patient had a recurrence. Microscopically there were stellate cells in an abundant myxoid stroma, yielding a diagnosis of odontogenic myxoma. Immunohistochemical examination showed positive reactions for smooth muscle actin, vimentin, and Ki-67. The treatment was surgical resection with a safety margin.
PE-232 - ODONTOGENIC MYXOMA: CLINICOPATHOLOGICAL ANALYSIS OF A CASE REPORT. SABRINA POZATTI MOURE, JOSÉ RICARDO SOUSA COSTA, EMERSON FERREIRA HONÓRIO, MILENE CASTILHOS