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ORAL LEUKOPLAKIA SCREENING WITH EARLY DIAGNOSIS OF SQUAMOUS CELL CARCINOMA: 9-YEAR FOLLOW-UP
OOOO Volume 129, Number 1 information regarding etiology with the parents and explanation of their aesthetic concerns regarding the occurrence in permanent dentition.
ODONTOGENIC MYXOMA: A SUNBURST RADIOGRAPHIC APPEARANCE MIMICKING A MALIGNANT LESION. JOSE ERIVALDO DA SILVA MENDES, STEFANNY TORRES DOS SANTOS, FLAVIA MARIA DE MORAES RAMOS-PEREZ, ANDREA DOS ANJOS PONTUAL, ELAINE JUDITE DE AMORIM CARVALHO, JUREMA FREIRE LISBOA DE CASTRO and, DANYEL ELIAS DA CRUZ PEREZ Odontogenic myxoma (OM) is a benign tumor derived from the odontogenic ectomesenchyme. This report describes a case of OM mimicking a malignant lesion. A 21-year-old female patient was referred for diagnosis of a swelling with 5 months of duration. Panoramic radiograph revealed a multilocular, mixed lesion, which involved the left mandibular body and ramus. On cone beam computed tomography, the lesion caused thinning and rupture of the buccal and lingual cortical bone. Root resorption and sunburst appearance were also observed. Malignant neoplasms were the main hypotheses of diagnosis. Under local anesthesia, an incisional biopsy was performed. Microscopically, there was a loose myxoid tissue, with scarce spindle cells without atypia. The diagnosis of OM was established. The patient was submitted to surgical resection, confirming the diagnosis of OM. Recurrence was not observed after 12 months. Although rare, OM should be considered in the differential diagnosis of lesions with sunburst radiographic appearance.
AGGRESSIVE DIFFUSE LARGE B-CELL LYMPHOMA IN ANTERIOR MAXILLARY REGION: CASE REPORT. GLEICY GABRIELA e e V.S.C. FALCAO, CAROLINA GUIMARAES BONFIM ALVES, PEDRO ANTONIO DE JESUS MOUREIRA, VINICIUS DA COSTA VIEIRA, PATRICIA MIRANDA e LINS KUSTERER LEITE RIBEIRO, LILIANE ELZE FALCAO and, VIVIANE ALMEIDA SARMENTO
ABSTRACTS
e87
AZEREDO DA SILVA LESSA NICOLAU, MIRIAM e MOREIRA SARRUF, ANA FLAVIA BEATRIZ JORDAO e SCHUELER DE ASSUMP¸C AO LEITE, ADRIANA TEREZINHA NEVES NOVELLINO ALVES, SIMONE DE QUEIROZ CHAVES LOURENCO ¸ and, JOSIANE COSTA RODRIGUES DE SA A 60-year-old black man complained of "toothache that created a lump" with 1 year of evolution. Anamnesis evidenced smoking and alcoholism for 48 years. At the extraoral examination, 2 hardened and painful lymph nodes were palpated in the left submandibular and cervical region, the largest one 4 cm in diameter. Intraoral examination revealed ulcerated swelling in the anterior left inferior gingiva and teeth mobility. The left mouth floor and ventral surface of the tongue were committed with a vegetative ulcer, hardened and painful to palpation. Panoramic radiograph showed diffuse radiolucent image in the anterior mandibular alveolar ridge and floating teeth. Biopsy was performed. Diagnostic hypothesis was squamous cell carcinoma. The histopathologic report confirmed the diagnosis of moderately differentiated squamous cell carcinoma. As part of the dental preparation, the upper teeth were extracted before the oncological treatment. The patient was referred for cancer treatment and is in the process of disease staging.
ORAL LEUKOPLAKIA SCREENING WITH EARLY DIAGNOSIS OF SQUAMOUS CELL CARCINOMA: 9-YEAR FOLLOW-UP. JOSEANE AMANDA THIEMANN BANDEIRA, ALINE HELEN DA SILVA CAMACHO, LUIZ CLAUDIO SANTOS THULER, LUIZ HENRIQUE LIMA DE ARAUJO, ANDREIA CRISTINA DE MELO, HELITON SPINDOLA ANTUNES and, DANIEL COHEN GOLDEMBERG Oral leukoplakia is the most common lesion with malignant potential that may occur in the oral cavity. A white 60-year-old woman who never smoked or ingested alcoholic beverage presented with the diagnosis of a right infiltrating lobular carcinoma of the breast on May 18, 2009, and suspicion of an oral leukoplakia with 10 years of evolution. After an incisional biopsy, a welldifferentiated superficially invasive squamous cell carcinoma was revealed approximately 1 week later. Subsequently, on August 17, 2010, a partial glossectomy was performed, and 6 months later a second incisional biopsy with a negative malignancy report was carried out. The patient is under control with no sequelae and no evidence of active disease. Early diagnosis of oral cancer through stomatologic screening of precursor epithelial lesions such as leukoplakia minimizes sequelae resulting from late diagnosis, improving not only quality of life but also patient survival rate.
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma and is rarely seen in the maxillofacial region. A case of DLBCL in a 50-year-old man who is immunocompetent (no reagent HIV-1 and -2, and human T-cell lymphotropic virus tests) is reported. The patient complained of a painful and aberrant mass in the anterior maxillary region with fast growing in 2 months. A facial computed tomography (CT) shows a large mass with soft tissue density, measuring approximately 7.4 £ 6.6 cm, which invaded and destroyed the maxillary bone. The incisional biopsy showed an undifferentiated malignant neoplasm compatible with lymphoma. Immunohistochemical analysis proved the lesion to be a DLBCL, strongly positive for CD20 and CD79 a, weakly positive for VS38 c+ and Bc16 e MUM1, and negative for CD3, cyclin A D1, CD7, C43, CD10, B CD30, and CS1-4. The proliferation index, as indicated by Ki-67 immunohistochemistry, was over 80%. The patient was referred for oncological treatment.
GIANT CELL FIBROMA - CASE REPORT. EMERSON LUCAS DA SILVA COIMBRA, JOSE DE ASSIS SILVA JUNIOR, WILLIAM ^ A, ANA FLAVIA NAPOLITANO CORRE SCHUELER DE e LEITE, SIMONE DE QUEIROZ CHAVES ASSUMPC ¸ AO ^ LOURENCO ¸ and, MONICA LAGE DA ROCHA
SQUAMOUS CELL CARCINOMA OF LARGE CLINICAL PROPORTIONS INVOLVING GINGIVA, MOUTH FLOOR, TONGUE, AND LYMPH NODES. QUEILA FREIRE BARRADAS, LARISSA
Giant cell fibroma is a type of fibrous tumor of the oral mucosa. The most common site is in the lower gingival area followed by the upper gingival area, tongue, and palate. The objective of this study is to present a case of giant cell fibroma in a 49year-old black woman with complaint of "an increase in the tip
ODONTOGENIC MYXOMA: A SUNBURST RADIOGRAPHIC APPEARANCE MIMICKING A MALIGNANT LESION. JOSE ERIVALDO DA SILVA MENDES, STEFANNY TORRES DOS SANTOS, FLAVIA MARIA DE MORAES RAMOS-PEREZ, ANDREA DOS ANJOS PONTUAL, ELAINE JUDITE DE AMORIM CARVALHO, JUREMA FREIRE LISBOA DE CASTRO and, DANYEL ELIAS DA CRUZ PEREZ Odontogenic myxoma (OM) is a benign tumor derived from the odontogenic ectomesenchyme. This report describes a case of OM mimicking a malignant lesion. A 21-year-old female patient was referred for diagnosis of a swelling with 5 months of duration. Panoramic radiograph revealed a multilocular, mixed lesion, which involved the left mandibular body and ramus. On cone beam computed tomography, the lesion caused thinning and rupture of the buccal and lingual cortical bone. Root resorption and sunburst appearance were also observed. Malignant neoplasms were the main hypotheses of diagnosis. Under local anesthesia, an incisional biopsy was performed. Microscopically, there was a loose myxoid tissue, with scarce spindle cells without atypia. The diagnosis of OM was established. The patient was submitted to surgical resection, confirming the diagnosis of OM. Recurrence was not observed after 12 months. Although rare, OM should be considered in the differential diagnosis of lesions with sunburst radiographic appearance.
AGGRESSIVE DIFFUSE LARGE B-CELL LYMPHOMA IN ANTERIOR MAXILLARY REGION: CASE REPORT. GLEICY GABRIELA e e V.S.C. FALCAO, CAROLINA GUIMARAES BONFIM ALVES, PEDRO ANTONIO DE JESUS MOUREIRA, VINICIUS DA COSTA VIEIRA, PATRICIA MIRANDA e LINS KUSTERER LEITE RIBEIRO, LILIANE ELZE FALCAO and, VIVIANE ALMEIDA SARMENTO
ABSTRACTS
e87
AZEREDO DA SILVA LESSA NICOLAU, MIRIAM e MOREIRA SARRUF, ANA FLAVIA BEATRIZ JORDAO e SCHUELER DE ASSUMP¸C AO LEITE, ADRIANA TEREZINHA NEVES NOVELLINO ALVES, SIMONE DE QUEIROZ CHAVES LOURENCO ¸ and, JOSIANE COSTA RODRIGUES DE SA A 60-year-old black man complained of "toothache that created a lump" with 1 year of evolution. Anamnesis evidenced smoking and alcoholism for 48 years. At the extraoral examination, 2 hardened and painful lymph nodes were palpated in the left submandibular and cervical region, the largest one 4 cm in diameter. Intraoral examination revealed ulcerated swelling in the anterior left inferior gingiva and teeth mobility. The left mouth floor and ventral surface of the tongue were committed with a vegetative ulcer, hardened and painful to palpation. Panoramic radiograph showed diffuse radiolucent image in the anterior mandibular alveolar ridge and floating teeth. Biopsy was performed. Diagnostic hypothesis was squamous cell carcinoma. The histopathologic report confirmed the diagnosis of moderately differentiated squamous cell carcinoma. As part of the dental preparation, the upper teeth were extracted before the oncological treatment. The patient was referred for cancer treatment and is in the process of disease staging.
ORAL LEUKOPLAKIA SCREENING WITH EARLY DIAGNOSIS OF SQUAMOUS CELL CARCINOMA: 9-YEAR FOLLOW-UP. JOSEANE AMANDA THIEMANN BANDEIRA, ALINE HELEN DA SILVA CAMACHO, LUIZ CLAUDIO SANTOS THULER, LUIZ HENRIQUE LIMA DE ARAUJO, ANDREIA CRISTINA DE MELO, HELITON SPINDOLA ANTUNES and, DANIEL COHEN GOLDEMBERG Oral leukoplakia is the most common lesion with malignant potential that may occur in the oral cavity. A white 60-year-old woman who never smoked or ingested alcoholic beverage presented with the diagnosis of a right infiltrating lobular carcinoma of the breast on May 18, 2009, and suspicion of an oral leukoplakia with 10 years of evolution. After an incisional biopsy, a welldifferentiated superficially invasive squamous cell carcinoma was revealed approximately 1 week later. Subsequently, on August 17, 2010, a partial glossectomy was performed, and 6 months later a second incisional biopsy with a negative malignancy report was carried out. The patient is under control with no sequelae and no evidence of active disease. Early diagnosis of oral cancer through stomatologic screening of precursor epithelial lesions such as leukoplakia minimizes sequelae resulting from late diagnosis, improving not only quality of life but also patient survival rate.
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma and is rarely seen in the maxillofacial region. A case of DLBCL in a 50-year-old man who is immunocompetent (no reagent HIV-1 and -2, and human T-cell lymphotropic virus tests) is reported. The patient complained of a painful and aberrant mass in the anterior maxillary region with fast growing in 2 months. A facial computed tomography (CT) shows a large mass with soft tissue density, measuring approximately 7.4 £ 6.6 cm, which invaded and destroyed the maxillary bone. The incisional biopsy showed an undifferentiated malignant neoplasm compatible with lymphoma. Immunohistochemical analysis proved the lesion to be a DLBCL, strongly positive for CD20 and CD79 a, weakly positive for VS38 c+ and Bc16 e MUM1, and negative for CD3, cyclin A D1, CD7, C43, CD10, B CD30, and CS1-4. The proliferation index, as indicated by Ki-67 immunohistochemistry, was over 80%. The patient was referred for oncological treatment.
GIANT CELL FIBROMA - CASE REPORT. EMERSON LUCAS DA SILVA COIMBRA, JOSE DE ASSIS SILVA JUNIOR, WILLIAM ^ A, ANA FLAVIA NAPOLITANO CORRE SCHUELER DE e LEITE, SIMONE DE QUEIROZ CHAVES ASSUMPC ¸ AO ^ LOURENCO ¸ and, MONICA LAGE DA ROCHA
SQUAMOUS CELL CARCINOMA OF LARGE CLINICAL PROPORTIONS INVOLVING GINGIVA, MOUTH FLOOR, TONGUE, AND LYMPH NODES. QUEILA FREIRE BARRADAS, LARISSA
Giant cell fibroma is a type of fibrous tumor of the oral mucosa. The most common site is in the lower gingival area followed by the upper gingival area, tongue, and palate. The objective of this study is to present a case of giant cell fibroma in a 49year-old black woman with complaint of "an increase in the tip