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P176
P270
Otolaryngology-Head and Neck Surgery, Vol 135, No 2S, August 2006
OBJECTIVES: 1. To evaluate the importance of surgical treatment for antrochoanal polyps. The surgery proposed was FESS associated to mini Caldwell-Luc. 2. To compare the patients operated on this surgery to the ones subjected only to FESS. METHODS: Retrospective analysis of patients with antrochoanal polyps submitted to surgery in Clinics Hospital–Faculty of Medicine of Ribeira˜o Preto–University of Sa˜o Paulo, between 1999 and 2004. RESULTS: Twenty-nine patients were evaluated; 23 of them were subjected only to FESS (Group 1) and 6 were subjected to FESS associated to Caldwell-Luc (Group 2). Nine patients from Group 1 had recurrence of their disease; 6 of them were then submitted to FESS associated to Caldwell-Luc. Thus, 12 patients were operated through FESS and Caldwell-Luc, and none of them had a recurrence. There is a statistically significant difference between the two groups (p⬍0.05) related to recurrences. CONCLUSIONS: These results suggest that FESS associated to Caldwell-Luc is more effective than FESS alone for the treatment of antrochoanal polyps.
P175 Asthma and Serum Eosinophilia in Nasal Polyposis Patients Mohsen Naraghi, MD (presenter); Armin Farajzadeh Deroee, MD; Mohammad Ghasemi, MD; Golnaz Heidari, MD Tehran Iran OBJECTIVES: Nasal polyposis (NP) is a chronic inflammatory disorder of the upper respiratory tract, which often coexists with asthma. The pathogenesis of NP is not fully understood. Eosinophils that are found in large numbers in nasal polyps and asthmatic airways are considered to have a crucial role in pathogenesis of nasal polyps and asthma. The aim of this retrospective study was to evaluate the prevalence of asthma and serum eosinophilia in patients with nasal polyposis and the control group who were patients with no associated respiratory disease. METHODS: Some 238 patients who had undergone nasal polyp surgery were retrospectively studied. The control group included 200 patients with no rhinologic problems. Age and sex were matched in both groups. The diagnosis of asthma was based on a documented physician diagnosis. Other data such as nasal symptoms, intolerance to aspirin, previous polyp surgery, and measures of serum eosinophilia were evaluated. RESULTS: In the NP group 18.7% were asthmatic and 81.3% nonasthmatic, in comparison with the control group in which 4.2% were asthmatic and 95.8% nonasthmatic. Values of asthma and serum eosinophilia in NP patients were significantly higher (p⫽0.005 and p⫽0.026, respectively) than in the control group. CONCLUSIONS: There is a greater prevalence of asthma and degree of serum eosinophilia in NP patients compared
with a control group. This would suggest that eosinophils may have a key role in the pathogenesis of these diseases. P176 Burden of Chronic Sinusitis: A Survey of Otolaryngologists David Sherris, MD (presenter); Angelos Stergiou, MD; Roman Casciano, MS; Laura M. Katz; W Tichenor New York NY OBJECTIVES: 1. Estimate prevalence of chronic sinusitis (CS) refractory to surgery and CS-related debilitation. 2. Determine satisfaction with CS treatments. METHODS: A survey was developed and administered to 30 otolaryngologists (2005). Data collected included physician demographics, patient volume, satisfaction with treatment options, perceived burden of disease, and estimated severity of CS and associated impairment. RESULTS: The sample consisted of medical practices across the U.S.; the majority had a mostly office/clinic-based practice (55.2%), followed by an equally hospital-based and office/ clinic-based practice (34.5%). Most physicians saw ⬎500 cases of adult CS annually (41.4%) while 31.1% saw 200-499, and 27.5% saw ?199. Physicians estimated that 27.0% of CS patients are surgery-refractory. Respondents were generally unhappy with current treatments, wished for more options to treat this unmet need (93.3%), and for a treatment proven efficacious and safe (90.9%). Physicians agreed that CS patients in general, and those with CS refractory to surgery, suffer from a severe and debilitating condition (86.7% and 93.3%, respectively) that causes discomfort and pain and often interferes with their ability to function normally (83.3% and 96.7%, respectively). Physicians estimated that a typical CS patient spends 122 days in CS-related discomfort, 53 days in pain, and 17 days unable to work. CONCLUSIONS: Physicians were generally dissatisfied with current treatment options available for CS and wished there were more options available. P177 Extended Sinusotomy for Refractory Maxillary Sinusitis Michael J. Rodriguez, MD (presenter); Roy R Casiano, MD Miami FL OBJECTIVES: To determine the role of extended maxillary sinusotomy in persistent maxillary sinusitis refractive to appropriate medical therapy and previous endoscopic maxillary sinusotomy. METHODS: Retrospective chart review was performed on patients who had an extended maxillary sinusotomy procedure at an academic hospital from 1997 to 2004. Complaints were limited to persistent rhinorhea, nasal obstruction and infraorbital discomfort. Disease was limited to the maxillary sinus and
Otolaryngology-Head and Neck Surgery, Vol 135, No 2S, August 2006
OBJECTIVES: 1. To evaluate the importance of surgical treatment for antrochoanal polyps. The surgery proposed was FESS associated to mini Caldwell-Luc. 2. To compare the patients operated on this surgery to the ones subjected only to FESS. METHODS: Retrospective analysis of patients with antrochoanal polyps submitted to surgery in Clinics Hospital–Faculty of Medicine of Ribeira˜o Preto–University of Sa˜o Paulo, between 1999 and 2004. RESULTS: Twenty-nine patients were evaluated; 23 of them were subjected only to FESS (Group 1) and 6 were subjected to FESS associated to Caldwell-Luc (Group 2). Nine patients from Group 1 had recurrence of their disease; 6 of them were then submitted to FESS associated to Caldwell-Luc. Thus, 12 patients were operated through FESS and Caldwell-Luc, and none of them had a recurrence. There is a statistically significant difference between the two groups (p⬍0.05) related to recurrences. CONCLUSIONS: These results suggest that FESS associated to Caldwell-Luc is more effective than FESS alone for the treatment of antrochoanal polyps.
P175 Asthma and Serum Eosinophilia in Nasal Polyposis Patients Mohsen Naraghi, MD (presenter); Armin Farajzadeh Deroee, MD; Mohammad Ghasemi, MD; Golnaz Heidari, MD Tehran Iran OBJECTIVES: Nasal polyposis (NP) is a chronic inflammatory disorder of the upper respiratory tract, which often coexists with asthma. The pathogenesis of NP is not fully understood. Eosinophils that are found in large numbers in nasal polyps and asthmatic airways are considered to have a crucial role in pathogenesis of nasal polyps and asthma. The aim of this retrospective study was to evaluate the prevalence of asthma and serum eosinophilia in patients with nasal polyposis and the control group who were patients with no associated respiratory disease. METHODS: Some 238 patients who had undergone nasal polyp surgery were retrospectively studied. The control group included 200 patients with no rhinologic problems. Age and sex were matched in both groups. The diagnosis of asthma was based on a documented physician diagnosis. Other data such as nasal symptoms, intolerance to aspirin, previous polyp surgery, and measures of serum eosinophilia were evaluated. RESULTS: In the NP group 18.7% were asthmatic and 81.3% nonasthmatic, in comparison with the control group in which 4.2% were asthmatic and 95.8% nonasthmatic. Values of asthma and serum eosinophilia in NP patients were significantly higher (p⫽0.005 and p⫽0.026, respectively) than in the control group. CONCLUSIONS: There is a greater prevalence of asthma and degree of serum eosinophilia in NP patients compared
with a control group. This would suggest that eosinophils may have a key role in the pathogenesis of these diseases. P176 Burden of Chronic Sinusitis: A Survey of Otolaryngologists David Sherris, MD (presenter); Angelos Stergiou, MD; Roman Casciano, MS; Laura M. Katz; W Tichenor New York NY OBJECTIVES: 1. Estimate prevalence of chronic sinusitis (CS) refractory to surgery and CS-related debilitation. 2. Determine satisfaction with CS treatments. METHODS: A survey was developed and administered to 30 otolaryngologists (2005). Data collected included physician demographics, patient volume, satisfaction with treatment options, perceived burden of disease, and estimated severity of CS and associated impairment. RESULTS: The sample consisted of medical practices across the U.S.; the majority had a mostly office/clinic-based practice (55.2%), followed by an equally hospital-based and office/ clinic-based practice (34.5%). Most physicians saw ⬎500 cases of adult CS annually (41.4%) while 31.1% saw 200-499, and 27.5% saw ?199. Physicians estimated that 27.0% of CS patients are surgery-refractory. Respondents were generally unhappy with current treatments, wished for more options to treat this unmet need (93.3%), and for a treatment proven efficacious and safe (90.9%). Physicians agreed that CS patients in general, and those with CS refractory to surgery, suffer from a severe and debilitating condition (86.7% and 93.3%, respectively) that causes discomfort and pain and often interferes with their ability to function normally (83.3% and 96.7%, respectively). Physicians estimated that a typical CS patient spends 122 days in CS-related discomfort, 53 days in pain, and 17 days unable to work. CONCLUSIONS: Physicians were generally dissatisfied with current treatment options available for CS and wished there were more options available. P177 Extended Sinusotomy for Refractory Maxillary Sinusitis Michael J. Rodriguez, MD (presenter); Roy R Casiano, MD Miami FL OBJECTIVES: To determine the role of extended maxillary sinusotomy in persistent maxillary sinusitis refractive to appropriate medical therapy and previous endoscopic maxillary sinusotomy. METHODS: Retrospective chart review was performed on patients who had an extended maxillary sinusotomy procedure at an academic hospital from 1997 to 2004. Complaints were limited to persistent rhinorhea, nasal obstruction and infraorbital discomfort. Disease was limited to the maxillary sinus and