- Email: [email protected]
P570 Serotype I, II, III distribution and antimicrobial susceptibility of Streptococcus agalactiae among Polish delivering women
Poster presentations / International Journal of Gynecology & Obstetrics 107S2 (2009) S413–S729
Conclusion: Septic pelvic thrombophlebitis is a consequence of puerperal bacterial infection ascending from placenta site to thrombosed uterine veins and consequently to ovarian veins. It was described for the first time in 1956 as thrombosis of vena ovarica. The incidence of this status is about 0.5–1.8 per 1000. There are several risk factors like immobility, thrombophilia (inherited or acquired), operative delivery, preeclampsia, hypertension, obesity, and smoking. P570 Serotype I, II, III distribution and antimicrobial susceptibility of Streptococcus agalactiae among Polish delivering women B. Wolski1 , J. Zegarska1 , R. Adamczak1 , W. Szymanski1 , A. Kaczmarek2 , M. Dorota2 . 1 The Obstetrics, Women’s Diseases and Gynecological Oncology Department of the Nicolaus Copernicus University in Toru´ n, Collegium Medicum in Bydgoszcz, 2 Department of Clinical Microbiology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun Objectives: Streptococcus agalactiae (group B streptococcus; GBS) is the predominant bacterial agent of neonatal sepsis and meningitis. Identification of GBS serotypes related to these complications is general purpose of developing globally effective vaccine. The aim of this study was to estimation frequency and antimicrobial drug resistance of I, II, and III serotypes of GBS strains. Materials and Methods: A total of 100 strains collected simultaneously from vaginal and anorectal swabs were tested using serotype latex test and Kirby–Bauer method. Results: The rates of serotypes were as follows: I – 30%, II – 7%, III – 32%, non I,II,III – 22% and non-typeable – 9%. The most frequent GBS isolates collected from vaginal and rectal swabs included III and I serotype respectively. Conclusions Our findings didn’t confirm relatedness between antimicrobial susceptibility and serotype of strains. Serotype III displayed multidrug antimicrobial resistance in contrast to other analyzed serotypes. P571 The status and related factors of reproductive tract infections among women suffering from various disasters: evidence-based research H. Lina, P. Xue. Department of Obstetrics and Gynaecology, West China Second University Hospital, Sichuan University Objectives: To evaluate the status and related factors of reproductive tract infections among women suffered from various disasters. Materials and Methods: Related original studies were searched. Meta-analysis or qualitative research were conducted according to the types of studies. Results: Fifteen original studies were found consisting of one case control study, two descriptive studies and twelve cross-sectional studies. The level of evidences varied from B to C. Qualitative research showed that many factors were related to the reproductive tract infections among displaced women. Conclusions: Our research showed it was important to improve the quality of original studies worldwide, as well as highlighted the serious status of reproductive tract infections among displaced women, and underscore its complex relationships with many factors.
S575
P572 Interleukin-6 concentrations in maternal and umbilical cord plasma and the early onset neonatal infection J. Zegarska1 , B. Wolski1 , R. Adamczak1 , W. Szymanski1 , W. Dobrzynski1 , M. Gruszka2 . 1. Department of Obstetrics, Women’s Diseases and Gynecological Oncology of the Nicolas Copernicus University in Toru´ n, Collegium Medicum in Bydgoszcz, 2 Department of Laboratory Medicine of the Nicolas Copernicus University in Toru´ n, Collegium Medicum in Bydgoszcz Objective: The aim of our study was to evaluate the diagnostic value of umbilical cord and maternal plasma Interleukin-6 (IL-6) concentrations in the presence or absence of the early onset neonatal infection. Study design: 80 mothers and their neonates were enrolled to our study. Maternal blood was collected during the active phase of labor and umbilical cord blood was collected immediately after delivery. Prospectively antepartum and intrapartum data were collected. We collect also all information concerning neonatal outcome but we focused on early onset neonatal infections. Results: There were no significant differences in IL-6 levels in maternal and umbilical cord plasma between healthy and infected neonates in both preterm and term neonates. In preterm group we observed higher level of IL-6 concentrations in umbilical cord plasma in infected group (53.27 pg/ml vs. 20.28 in healthy group) although this difference wasn’t significant, p = 0.07. Level of IL-6 in umbilical cord plasma higher than 100 pg/ml was correlating with the presence of severe neonatal infection and other perinatal disorders, including periventricular leukomalacia. Higher level of IL-6 in umbilical cord comparing with maternal plasma was associated with neonatal infection in both term and preterm newborns, p = 0.008. Conclusions: High level of IL-6 in umbilical cord plasma correlates with severity of neonatal infection and with the presence of other perinatal disorders. Higher level of IL-6 in umbilical cord comparing with delivering mother is associated with an increased risk of early onset neonatal infections. More investigations are needed to prove the role of comparing maternal and umbilical cord blood level of interleukin 6 in prediction of neonatal infections. P573 Alteration of the menstrual cycle in adolescence: early clinical manifestation of the metabolic syndrome? I. Bouzas, C. Braga, L. Leao Introduction: The relationship between menstrual cycle and the Metabolic Syndrome (MS) is insulin resistance/hyperinsulinemia. The mitogenic effects of hyperinsulinemia may affect the menstrual cycle through their direct action on the ovaries, adrenal glands, hepatic production of SHBG, and on the regulation of the feedback of the gonadotropins. These alterations may appear early, preceding the metabolic alterations of the MS. Objective: Evaluate the menstrual cycle in teens who present risk factors for the MS. Material and Method: Observational, comparative, and transversalcut study with 37 female adolescents between 12 and 19 years, and the presence of at least one of the following risk factors for MS: Overweight, Obesity, “Acanthosis Nigricans”, Polycystic Ovary Syndrome (POS). All the adolescents underwent a clinical evaluation, with gathering of anthropometric data, blood pressure, and laboratory evaluation composed of Lipidogram, evaluation of glycose and hormonal metabolism. Two groups were created according to the menstrual cycle pattern. G-1 adolescents with irregular cycles since menarche, and G-2 with regular menstrual cycles since menarche. Results: From the 37 adolescents evaluated, 27 formed G-1 and 10 formed G-2. The average gynecological age was 4.6 years, between the two groups. 10 of the adolescents from G-1 presented MS.
Conclusion: Septic pelvic thrombophlebitis is a consequence of puerperal bacterial infection ascending from placenta site to thrombosed uterine veins and consequently to ovarian veins. It was described for the first time in 1956 as thrombosis of vena ovarica. The incidence of this status is about 0.5–1.8 per 1000. There are several risk factors like immobility, thrombophilia (inherited or acquired), operative delivery, preeclampsia, hypertension, obesity, and smoking. P570 Serotype I, II, III distribution and antimicrobial susceptibility of Streptococcus agalactiae among Polish delivering women B. Wolski1 , J. Zegarska1 , R. Adamczak1 , W. Szymanski1 , A. Kaczmarek2 , M. Dorota2 . 1 The Obstetrics, Women’s Diseases and Gynecological Oncology Department of the Nicolaus Copernicus University in Toru´ n, Collegium Medicum in Bydgoszcz, 2 Department of Clinical Microbiology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun Objectives: Streptococcus agalactiae (group B streptococcus; GBS) is the predominant bacterial agent of neonatal sepsis and meningitis. Identification of GBS serotypes related to these complications is general purpose of developing globally effective vaccine. The aim of this study was to estimation frequency and antimicrobial drug resistance of I, II, and III serotypes of GBS strains. Materials and Methods: A total of 100 strains collected simultaneously from vaginal and anorectal swabs were tested using serotype latex test and Kirby–Bauer method. Results: The rates of serotypes were as follows: I – 30%, II – 7%, III – 32%, non I,II,III – 22% and non-typeable – 9%. The most frequent GBS isolates collected from vaginal and rectal swabs included III and I serotype respectively. Conclusions Our findings didn’t confirm relatedness between antimicrobial susceptibility and serotype of strains. Serotype III displayed multidrug antimicrobial resistance in contrast to other analyzed serotypes. P571 The status and related factors of reproductive tract infections among women suffering from various disasters: evidence-based research H. Lina, P. Xue. Department of Obstetrics and Gynaecology, West China Second University Hospital, Sichuan University Objectives: To evaluate the status and related factors of reproductive tract infections among women suffered from various disasters. Materials and Methods: Related original studies were searched. Meta-analysis or qualitative research were conducted according to the types of studies. Results: Fifteen original studies were found consisting of one case control study, two descriptive studies and twelve cross-sectional studies. The level of evidences varied from B to C. Qualitative research showed that many factors were related to the reproductive tract infections among displaced women. Conclusions: Our research showed it was important to improve the quality of original studies worldwide, as well as highlighted the serious status of reproductive tract infections among displaced women, and underscore its complex relationships with many factors.
S575
P572 Interleukin-6 concentrations in maternal and umbilical cord plasma and the early onset neonatal infection J. Zegarska1 , B. Wolski1 , R. Adamczak1 , W. Szymanski1 , W. Dobrzynski1 , M. Gruszka2 . 1. Department of Obstetrics, Women’s Diseases and Gynecological Oncology of the Nicolas Copernicus University in Toru´ n, Collegium Medicum in Bydgoszcz, 2 Department of Laboratory Medicine of the Nicolas Copernicus University in Toru´ n, Collegium Medicum in Bydgoszcz Objective: The aim of our study was to evaluate the diagnostic value of umbilical cord and maternal plasma Interleukin-6 (IL-6) concentrations in the presence or absence of the early onset neonatal infection. Study design: 80 mothers and their neonates were enrolled to our study. Maternal blood was collected during the active phase of labor and umbilical cord blood was collected immediately after delivery. Prospectively antepartum and intrapartum data were collected. We collect also all information concerning neonatal outcome but we focused on early onset neonatal infections. Results: There were no significant differences in IL-6 levels in maternal and umbilical cord plasma between healthy and infected neonates in both preterm and term neonates. In preterm group we observed higher level of IL-6 concentrations in umbilical cord plasma in infected group (53.27 pg/ml vs. 20.28 in healthy group) although this difference wasn’t significant, p = 0.07. Level of IL-6 in umbilical cord plasma higher than 100 pg/ml was correlating with the presence of severe neonatal infection and other perinatal disorders, including periventricular leukomalacia. Higher level of IL-6 in umbilical cord comparing with maternal plasma was associated with neonatal infection in both term and preterm newborns, p = 0.008. Conclusions: High level of IL-6 in umbilical cord plasma correlates with severity of neonatal infection and with the presence of other perinatal disorders. Higher level of IL-6 in umbilical cord comparing with delivering mother is associated with an increased risk of early onset neonatal infections. More investigations are needed to prove the role of comparing maternal and umbilical cord blood level of interleukin 6 in prediction of neonatal infections. P573 Alteration of the menstrual cycle in adolescence: early clinical manifestation of the metabolic syndrome? I. Bouzas, C. Braga, L. Leao Introduction: The relationship between menstrual cycle and the Metabolic Syndrome (MS) is insulin resistance/hyperinsulinemia. The mitogenic effects of hyperinsulinemia may affect the menstrual cycle through their direct action on the ovaries, adrenal glands, hepatic production of SHBG, and on the regulation of the feedback of the gonadotropins. These alterations may appear early, preceding the metabolic alterations of the MS. Objective: Evaluate the menstrual cycle in teens who present risk factors for the MS. Material and Method: Observational, comparative, and transversalcut study with 37 female adolescents between 12 and 19 years, and the presence of at least one of the following risk factors for MS: Overweight, Obesity, “Acanthosis Nigricans”, Polycystic Ovary Syndrome (POS). All the adolescents underwent a clinical evaluation, with gathering of anthropometric data, blood pressure, and laboratory evaluation composed of Lipidogram, evaluation of glycose and hormonal metabolism. Two groups were created according to the menstrual cycle pattern. G-1 adolescents with irregular cycles since menarche, and G-2 with regular menstrual cycles since menarche. Results: From the 37 adolescents evaluated, 27 formed G-1 and 10 formed G-2. The average gynecological age was 4.6 years, between the two groups. 10 of the adolescents from G-1 presented MS.