Polymorphism of the mouse TNF-α locus: sequence studies of the 3′-untranslated region and first intron

Gene, 136(1993)379 0 1993 Elsevier Science Publishers

GENE

B.V. All rights reserved.

319

0378-l 119/93/$06.00

07561

Erratum Gene, 129 (1993) 279-283 0 1993 Elsevier Science Publishers

GENE

B.V. All rights reserved. 0378-l 119/93/$06.00

07178

Polymorphism of the mouse TNF-a locus: sequence studies of the 3’-untranslated region and first intron (Recombinant DNA; tumor necrosis factor; lupus; mutation; Mus; DNA sequencing)

Bruce Beutler and Tracy Brown Howard Hughes Medical Institute and Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75235-9050, USA Received by J.A. Hoch: 16 August

1993; Accepted:

29 August

1993; Received at publishers:

Due to a Publisher’s error, Fig. 1 of ‘Polymorphism of the mouse TNF-a locus: sequence studies of the 3’-untranslated region and first intron (B. Beutler and T.

3 September

1993

Brown; Gene 129 (1993) 279-283) contained several mistakes. The corrected Fig. 1 is shown below.

(rrAmAT, 435

+l

469

AAATAA

I

TGA

749

C57Bl6

T+C

HeN 96

369 T-C

NOD 369 A+G

G+A

T+C

96 130

C+T I

726

369

A-G

Balblc

T-C

SWR

I

96

369

164 166

NZW

438

GACAC

Mus spretus 96 135164

369 375 436

Mus castaneus A-G

T-C

96

I

AG I 496

369

I

I

I

100

200

300

I

400

Fig. 1. Mutations in the 3’UTR of the mouse TNF, presented with respect shown as a black box. AATAAA indicates the position of the polyadenylation and insertions

are indicated

C+T I 726

I

I

I

500

600

700

MIJS

shanghai

1@PI

to the reference strain C57B/6. The A+T-rich element in the 3’-UTR is signal sequence. A, deletion of a nt. Mutations are indicated by arrows,

by brackets.

Correspondence to: Dr. B. Beutler, Howard Hughes Medical Institute, TX 752359050, USA. Tel. (1-214) 689-5006; Fax (1-214) 689-5066.

U.T. Southwestern

Medical

Center,

5323 Harry

Hines Blvd., Y5.210, Dallas,