August 1960
SCIENTIFIC EDITION
Oleanolic Acid Acetate.-The residue A (3.4Gm.) from the acetone mother liquor described above was acetylated with acetic anhydride and m i d i n e . The crude acetate on repeated crystallization from acetone afforded oleanolic acid acetate (0.5 Gm.)p m. P. 264-266'8 [a111f 75" (CHCL). The mixed melting point with an authentic specimen of oleanolic acid acetate did not show any depression. Anal.-Calcd. for C X ~ H ~ D C,O 77.06; ~: H, 10.11. Found: C, 76.71;H, 10.08. Methyl Oleanolate Acetate.-The acetate was esterified with an ethereal solution of diazomethane and the ester on crystallization from acetone yielded methyl oleanolate acetate, m. p. 216-218', [ a ] -k~ 68.6' (CHCls). The mixed melting point with an authentic specimen did not show any depression.
563
Extraction with 95% Ethanol The plant material after the extraction with henzene, was extracted in a &-&let apparatuswith 95% ethanol for ten hours. The residue after the removal of ethanol showed a negative test for alkaloids and did notyield any material,
REFERENCES
, ~ & ~ s & , " , o ~ i n$in:;), ~&N ~ &~&e ~~$ ~ ?& ~i ~ ; t ~ ; and Industrial Research, New Delhi India 1956 p. 180.
J. ~
~ d ~ ~ t ~ Venkatarhalam, ~ ~ ~ ~ K.*i (3) Chauhan, R. N. S., and Tewari, J. D., ibid., 29, 386
Rajappa, S., J . Sci.'lnd. Research India', 17B,73(1958). B ~ ~ ~vol,14, Publ~sh~ng CO.Inc.. New York, N. Y..1940, p. 91.
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Synthesis and Organisalion in the Bacterial Cell. By E. F. GALE. John Wiley & Sons, Inc., 440 Fourth Ave., New York 16, N. Y., 1959. vii 110 pp. 12.5 X 18.5cm. This is a compilation of material which formed the basis of three Ciba lectures in microbial biochemistry on Structure and organization in the bacterial cell, Amino acid incorporation, and Nucleic acid and protein synthesis.
P r k i s de Botanique. Vol. 2. S y s t h a t i q u e des 3ngiosperme.s. By P. CROTO. Masson et Cie., Editeurs, 120 boulevard Saint-Germain, Paris 6",France, 1960. viii 429 pp. 16 X 21 cm. Price NF. 34,000. This second volume on pharmaceutical botanicals (in French) considers the angiosperms (true flowering plants).
The Lynn Index. A Bibliography of Phytochemistry. Monograph I V. Organized and edited by JOHN W. SCHERMERHORN and MAYNARD W. QUIMBY. Massachusetts College of Pharmacy, Longwood Ave., Boston 15,Mass., 1960. 70 pp. 15 X 23 cm. This monograph covers the Glumiforae order, including the Cyperaceae and Gramineae families. The plan for the series was described in the review of monograph I in THISJOURNAL, 47,232(1958).
Clinical Chemical Pathology. By C. H. GRAY. Edward Arnold, Ltd., London, England, 1959. Distributed in the U. S. by the Williams & Wilkins Co., 428 East Preston St., Baltimore 2, Md. vii 160 pp. 13 X 18.5 cm. Price 63.75. This is the second edition of a pocket-size. handy reference on renal function, acid-base balance. fluid balance (edema) (salt and water deficiencies), liver function tests, chemical pathology of diabetes, Ca and P, disturbances of fat metabolism, chemical pathology of alimentary tract, and biochemical tests in endocrine disease. Other subjects discussed very briefly include special tests and routine clinical tests.
Pricis D'Anatomie et de Physiologie Humaines. By Y. RAOUL. Masson et Cie., h i t e u r s , 120 boulevard Saint-Germain, Paris 6*,France, 1960. viii 379 pp. 16 X 21 cm. Price NF. 48,000. This book (in French) presents a concise course in physiology for pharmacy students. It is one of a series of textbooks for the pharmaceutical curriculum.
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Book Notices
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741(1954). (4) Govindachari T. R., Nagarajan K. Pai B. R.. and
(1952);
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Antibiotics Annual 1959-1960. Proceedings of the 7th Annual Symposium on Antibiotics. Antibiotica, Inc.. 30 East 60th St.,New York 22,N. Y., 1960. xvii 1034 pp. 17 X 25.5 cm. Price Heterocyclic Chemistry. By ALAN R. KATRITZKY $15. and JEANNE M. LAGOWSKI. John Wiley & Sons, This volume comprises the proceedings of the Inc., 440 Fourth Ave., New York 16, N. Y., seventh annual symposium on antibiotics held 1960. 274 pp. 13.5 X 20 cm. Price $4.75. November 4-6, 1959, in Washington, D. C. I t Designed as a low-cost book for students, the includes all the reports that were presented. I t is, authors have attempted to present a condensed without doubt, the most comprehensive authoritaversion of basic heterocyclic chemistry required by tive compilation of research results on new and esgraduate students and researchers. The authors tablished antibiotics for the period between the have been frugal with words but liberal with almost symposiums of 1958 and 1959. I t is a must for reference libraries in the health sciences. 2,500 formulas.
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