PHENOLSULFONPHTHALEIN DETERMINATION AND GROSS HEMATURIA
729
left. That is the approximate corrected phenolsulfonphthalein percentage. For example; if the phenolsulfonphthalein in the filtrate is 30 per cent and there are 10 cc of blood in the sample, the actual amount of phenolsulfonphthalein would be 33 per cent and if 20 cc of blood were present, the actual amount of phenolsulfonphthalein would be 36 per cent. DISCUSSION
A method to determine the phenolsulfonphthalein in the presence of grossly bloody urine has been presented. It can be seen that even without correction, the amounts of phenolsulfonphthalein present in the filtrate of samples containing up to 20 cc of blood per sample would not change the clinical interpretation unduly. For this reason, rough approximations of the amount of blood are adequate. When amounts of blood in the urine sample are greater than 20 cc, the readings are likely to be erroneous. During our preliminary determinations, this may have been due to a technical error, but we believed that if it were present during our relatively careful determinations, it would likely be present during clinical determinations. In our own clinical application of this test, we have found that amounts of blood in the specimens have seldom exceeded 20 cc. When there is more blood than 20 cc per specimen, usually clots are present. Irrigation is often necessary to obtain the specimen, so that another factor of error is introduced. Therefore, we suggest that any samples containing more than 20 cc of blood be discarded. SUMMARY
A method for determining the phenolsulfonphthalein output in the presence of gross hematuria has been presented. Easily obtainable materials and reagents are used. It is a clinically accurate method when less than 20 cc of blood per specimen is present.
PROGRAM, NEW YORK SECTION Combined Meeting with Section on Genito-Urinary Surgery of Academy of Medicine
Yale Club, New York City, November 15, 1950 Collation, 6:30 p.m.; dinner, 7:00 p.m.; meeting, 8:3(p.m. Paper of the Evening Carcinoma of Bladder: Evaluation of Total Cystectomy and Other Methods, b£Dr. Fletcher H. Colby, Director of Urology, Massachusetts General Hospital, Boston, Mass. Discussion Drs. Thomas J. Kirwin, Victor F. Marshall, and H. W. Jacox