Prostaglandin bibliography

PROSTAGLANDINS

PROSTAGLANDIN BIBLIOGRAPHY Selected citations from The Upjohn Company Bibliography James R. Weeks, Ph,D.

BIOCHEMISTRY - TRANSPORT Barry, E . , Hall, W . J . , and Martin, J . D . G . : Prostaglandin E 1 and the Movement of Salt and Water in Frog Skin (Rana Temporaria). Gen. Pharmacol. 6: 141-150, 1975. Bito. L.: Saturable, Energy-Dependent, Transmembrane Transport of Prostaglandins Against Concentration Gradients. Nature (Lond) 256: 134-136, 1975. Chase, L.R.: Selective Proteolysis of the Receptor for Parathyroid Hormone in Renal Cortex. Endocrinology 96: 70-76, 1975. Cagen, L.M., Pisano, J . J . , Ketley, J . N . , Habig, W.H., and Jakoby, W.B.: The Conjugation of Prostaglandin A 1 and Glutalhione Catalyzed by Homogeneous Glutathione S-Transferases from Human and Rat Liver. Biochim. Biophys. Acta. 398: 205-208, 1975. Ercan, Z .S. and R.K. Turker: Potentiation of the Effect of Histamine by PGE 2 in the Isolated Perfused Rabbit Kidney and Guinea-Pig Lung. Experientia 31: 333-335, 1975. Lee, S.C. and L. Levine: Purification and Regulatory Properties of Chicken Heart Prostaglandin E 9-Ketoreductase. J. Biol. Chem. 250: 45494555, 1975. Hall, W.J. and M.G. O~Regan: Effect of Prostaglandin E 1 and Other Factors on the Electrical Excitability of Isolated Frog Skin (Rana Temporaria). Gen. Pharmacol. 6: 151-154, 1975. Jio, J . , J s u , C . H . J . , and Mizuba, S .: Microbial Transformation of Prostaglandin A2. Dev. Ind. Microbiol. 15: 345-352, 1974. Johns, A. and M.J. Wooster: The Inhibitory Effects of Prostaglandin E 1 on Guinea-Pig Ureter. Can. J. Physiol. Pharmacol. 53: 239-247, 1975. Kocsar, L., Meretey, K . , Virag, S. and G. Kovacs: Labelling of Prostaglandins with Radioiodine and Testing of the Biological Characteristics of Iodinated Derivatives. Izotoptechnika 17: 355-360, 1974; (Hungarian).

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PROSTAGLANDINS Nogteren, D.H.: The Determination of Prostaglandin Metabolites in Human Urine. J . Biol. Chem. 250: 2808-2812, 1975. Polet, H. and Levine, L.: Partial Purification and Characterization of Prestaglandin A Isomerase from Rabbit Serum. Arch. Biochem. Biophys. 168: 96-103, 1975. Rao, C .V.: The Presence of Discrete Receptors for Prostaglandin F2~in the Cell Membranes of Bovine Corpora Lutea. Biochem. Biophys. Res. Commun. 64: 416-424, 1975. Raz, A . , Schwartzman, M . , Kenig-Wakshal, R . , and Perl, E.: The Specificity of Antisera to Conjugates of Prostaglandins E with Bovine Serum Albumin and Thyreglobulin. Eur. J . Biochem. 53: 145-150, 1975. Wheeler, G . E . , and Epand, R.M.: Prostaglandin E 1 Anomalous Effects on Glucose Production in Rat Liver. Mol. Pharmacol. 11: 335339, 1975. BIOSYNTHESIS - DEGRADATION Attsllah, A . A . , Duchesne, M.J. and Lee, J . B .: Metabolism of Prostaglandin A II. Isolation, Characterization, and Synthesis of PGA1 Renal Metabolites. Life Sci. 16: 1743-1752, 1975. Barrowman, J . A . , Bennett, A . , Hillenbrand, P . , Rolles, K ., Pollock, D . J . , and Wright, J .T.: Diarrhoea in Thyroid Medullary Carcinoma: Role of Prostaglandins and Therapeutic Effect of Nutmeg. Br. Med. J . 3: 11-12, 1975. Bedwani, J . 11, and Marley, P . B . : Enhanced Inactivation of Prostaglandin E 2 by the Rabbit Lung During Pregnancy or Progesterone Treatment. B r. J . Pharmacol. 53: 547-554, 1975. Bennett, A . , McDonald, A . M . , Simpson, J . S . , and Stamford, I . F . : Breast Cancer, Prostaglandins, and Bone Metastases. Lancet 1: 1218-1220, 1975. Blackwell, G . J . , Flower, R . J . , Vane, J . R . : Some Characteristics of the Prostaglandin Synthesizing System in Rabbit Kidney Microsomes. Biochim. Biophys. Acta 398: 178-190, 1975. Burstein, S . , Varanelli, C . , and Slade, L . T . : Prostaglandins and Cannabis Ill. Inhibition of Biosynthesis by Essential Oil Components of Marihuana. Biochem. Pharmacol. 24: 1053-1054, 1975.

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Chart, J . A . , Nagasawa, M., T a k e ~ c h i , C., and Sih, C . J . : On Agents Favoring Prostaglandin F Formation During Biosynthesis. Biochemistry 14: 2987-2991, 1975. Cook, H.W. and Lands, W.E.M.: Evidenee for an Activating Factor Formed During Prostaglandin Biosynthesis. Biochem. BiophFs. Res. Commun. 65: 464-471, 1975• C o r e y , E . J . , Ensley, H . E . , Hamberg, M., and Samuelsson, B.: Disparate

Pathways of Prostaglandtn Biosynthesis in Coral and Mammalian Systems. J . Chem. Soc. (Chem. Commun.): 277-278, 1975. Damas, J . , and Bourdon, V.: Release of Arachidonic Acid b y Bradykinin. Cr. Soc. Biol. (Paris) 168: 1445-1448, 1974; (French). Danon p A . , Heimberg, M., and Oates, J .A.: Enrichment of Rat Tissue Lipids with Fatty Acids That Are Prostaglandin Precursors. Biochim. Biophys. Acta 388: 318-330, 1975. Danon i A . , Chang, L . C . T . , Sweetman, B . J . , Nies, A . S . , and Oates, J . A . :

Synthesis of Prostaglandins by the Rat Renal Papilla i n Vitro. Mechanism of Stimulation b y Angiotensin II. Biochim. Biophys. Acta 388: 71-83, 1975.

Deby, C •, and Damas, J . : Influance of Tryptophan on the Hypotensive Effect of Arachidonic Acid. Arch. Int. Physiol. Biochim. 82: 742-744, 1974; (French). Deby, C . , Descamps, M., Binon, F . , and Bacq, Z.M.: Correlation Between Anti-Inflammatory Properties and inhibition of Prostaglandin Biosynthesis i n Vitro. Biochem. Pharmaool. 24: 1089-1092, 1975. Duchesne, M . J . , Attallah, A . A . , and Lee, J .B .: Human Serum Albumin (HSA) Decreases Prostaglandin A 1 (PGA 1) Metabolism. Bieehem. Biophys. Res. Commun. 64: 196-203, 1975. Dunbar, L.M., and Bailey, J.M.: Enzyme Deletions and Essential Fatty Acid Metabolism in Cultured Cells. J. Biol. Chem. 250: 1152-1153, 1975. Gimbrone, M . A . , J r . and Alexander, R .W.: Angiotensin II Stimulation of Prostaglandin Production in Cultured Human Vascular Endothelium. Science 189: 219-220, 1975. Gross, K . B . , and Gillis, C .N.: Metabolism of Prostaglandin A 1 by the Perfused Rabbit Lung. Biochem. Pharmacol. 24: 1441-1444, 1975.

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Gustavii, B.: Release of Lysosomal Acid Phosphatase into the Cytoplasm of Decidual Ceils Before the Onset of Labour in Humans. Br. J. Obstet. Gynascol. 82: 177-181, 1975. Hagenfeldt, L. and Wennmalm, A. : T u r n o v e r of a Prostaglandin P r e c u r s o r , Araehidonic Acid, in Rheumatoid Arthritis. Eur. J . Clin. Invest. 5: 235-239, 1975. Ham, E . A . , Cirillo, V . J . , Zanetti, M.E., and Kuehl, F . A . , J r . : EstrogenDirected Synthesis of Specific Prostaglandins i n Uterus. Proc. Natl. Acad. Sci. USA 72: 1420-1424, 1975. J u n g , A . , Schlegel, W., Jackisch, R . , Friedrich, E . F . , Wendel, A . , and Ruehrich, M .F. : 15-Hydroxyprostaglandin-Dehydrogenase from Human Placanta, I. Isolation and Characterization. Hoppe-SeylerVs Z. Physiol. Chem. 356: 787-798, 1975; (German). Krupp, P . , and Wesp, M.: Inhibition of Prostaglandin Synthetase by Psychotropic Drugs. Experientia 31: 330-331, 1975. Ku, E . C . , and Wasvary, J .M .: Inhibition of Prostaglandin Synthase by Pirprofen Studies with Sheep Seminal Vesicle Enzyme. Biochim. Biophys. Acta 384: 360--.368, 1975. Lerner, L . J . , Galliani, G . , Carminati, P . , and Mosea, M.C.: Anti-Fertility Drugs: Novel Non-Hormonal Compounds That Inhibit Prostaglandin Metabolism. Nature (Lond) 256: 130-132, 1975. Luckner, G . , and Renz, P.: On the Phospholipase Activity in Bovine Seminal Vesicles and Its Possible Role in the Regulation of the Prostaglandin Biosynthesis. Z. Naturforsch (C)30: 429-433, 1975. Ogata, H., and Nomura, T .: Isolation and Identification of Prostaglandin E2 from the Gastrointestinal Tract of Shark Triakis SeylHa. Biochim. Biophys, Acta 388: 84-91, 1975. Pace-Asciak, C. : Prostaglandin 9-Hydroxydehydrogenase Activity in the Adult Rat Kidney. Identification, Assay, Pathway, and Some Enzyme Properties. J. Biol. Chem. 250: 2789-2794, 1975. Ruckrich, M . F . , Wendel, A . , Schlegel, W., Jackisch, R . , and J u n g , A.: 15-Hydroxyprostaglandin-Dehydrogenase from Human Placenta, II. Steady State Kinetics and the Influence of Prostaglandin F 2 Analogs. Hoppe-Seyler's Z. Physiol. Chem. 356: 799-909, 1975; (German).

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Srivastsva, K . C . , Fog, T . , and Clausen, J . : The Synthesis of Prostagiandins in Platelets from Patients with Multiple Sclerosis. Acta Neurol. Seand. 51: 193-199, 1975. Van Den Berg, G . , Bultsma, T . , and Nauta, W.T .: Inhibition of Prostaglandin Biosynthesis by 2 - A r y l - l , 3 - I n d a n d i o n e s . Biochem. Pharmacol. 24: 1115-1119, 1975. BLOOD - PLATELETS MacIntyre, D . E . , and Gordon, J . L . : Prostaglandin Receptor on Blood Platelets: Effect of Thiol Reagents on Inhibition of Platelet Aggregation by Prostaglandin E 2 . Biochem. Soc. T r a n s . 2: 1265-1269, 1974. Malmstein, C . , Hamberg, M., Svensson, J . , and Samuelsson, B.: Physiological Role of an Endoperoxide in Human Platelets: Hemostatic Defect Due to Platelet Cyclo-oxygenase Deficiency. Proc. Natl. Acad. Sci. USA 72: 1446-1450, 1975. Myatt, L., and Elder, M.G. : The Effects on Platelet Aggregation of Oral Prostaglandin E2 Used for the Induction of Labour. Br. J. Obstet. Gynaeeol. 82: 449-452, 1975. Sinaros, Z . , Zamboulis, C . , Kartalis, G., Koratzis, J . , and Valtis, D.: The Influence of Prostagiandins E 1 and E 2 on Pletelet Aggregation in Mammals. Hasmatological (Pavia). 59: 173-180, 1974. Vaage, J . , and Piper, P .J.: The Release of Prostaglandin-Like Substances During Platelet Aggregation and Pulmonary Microembolism. Acta Physiol. Scand. 94: 8-13, 1975. Valone, F . J . , Austen, K . F . , and Goetzl, E . J . : Inhibition by Aspirin of the Enhanced Migration of Human Platelets in Response to Prostaglandin Precursors. Immunol. Commun. 4: 139-148, 1975. CARDIOVASCULAR - RENAL Aitken, M.M., and Sanford, J .: Effects of Prostaglandins in Calves. Br. J . Pharmacol. 54: 266P-267P, 1975. Alexander, R.W., Kent, K.M., Pisano, J . J . , Keiser, H . R . , and Cooper, T.: Regulation of Postooolusive Hyperomia by Endogenously Synthesized Prostagiandins in the Dog Heart. J . Clin. Invest. 55: 1174-1181, 1975.

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Anderson, F . L . , T s a g a r i s , T . J . , J u b i z , W., and Kuida, H.: Prostaglandin F and E Levels During Endotoxin-Induced Pulmonary Hypertension in Calves. Am. J . Physiol. 229: 1479-1482, 1975. Cho, K . J . , Chuang, V . P . , and Reuter, S .R.: Pz~staglandin E1 as a Pharmacoangiographic Agent for Arterial Portography. Radiology 116: 207209, 1975. Cioffi, R . F . , O'Connell, J . M . B . , and Shalhoub, R . J . : Effect of Prostaglandin A 1 on Acute Renal Failure in the Rat. Nephron. 15: 29-34, 1975. D r es s i er, W . E . , Rossi, G . V . , Orzechowski, R .F.: Evidence That Renal Vasodilation by Dopamine in Dogs Does Not Involve Release of Prostaglandin. J . Pharm. Pharmacol. 27: 203-204, 1975. Forster, W., S c h r o r , K . , and Weiss, M.: Interactions Between Prostsglandins E 2 and F2~and Isoprenaline in Dog~s Heart in Situ. Acta Biol. Med. Germ. 34:501-506, 1975; (German). Fukushima, K. : Cardiovascular Effects of Various Agents on Cardiogenic Shock. Jap. Circ. J . 38: 509-513, 1974. Handa, J . , Yoneda, S . , Matsuda, M . , and Hands, H.: Prostaglandins and Cerebral Circulation: Effects of Prostaglandins A 1, E 2 , and F2~on the Feline Basilar A r t e r y . No To Shinkei 26: 919-925, 1974; (Japanese). Kadowitz, P . J . , J o i n e r , P . D . , and Hyman, A . L . : Comparison of the Effects of Prostaglandins F I ~ , F2:×, Fl/~, and F2~ on the Canine Pulmonary Vascular Bed. Proc. Soc. Exp. Biol. Med. 149: 356-361, 1975. Kadowitz, P . J . and Hyman, A . L . : Differential Effects of Prostaglandins A 1 and A2 on Pulmonary Vascular Resistance in the Dog. Proc. Soc. Exp. Biol. Med. 149:282-286, 1975. Kadowitz, P . J . , J o i n e r , P . D . , Matthews, C . S . , and Hyman, A . L . : Effects of the 15-Methyl Analogs of Prostaglandins E2 and F2~on the Pulmonary Circulation in the Intact Dog. J . Clin. Invest. 55: 937-944, 1975. Kauker, M .L.: T r a c e r Microinjection Studies of Prostaglandin E 2 Transport in the Rat Nephron. J . Pharmacol. Exp. T h e r . 193: 274-280, 1975. Kono, T . , Yoshimi, T . , and Endo, J . : Clinical Studies on the Effects of Prostaglandin A 2 on Water-Electrolyte Metabolism and the ReninAngiotensin-Aldosterone System. Jap. J . Clin. Med. 32: 27482751, 1974; (Japanese).

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Kono, T . , Yoshimi, T . , Oseko, F . , Narmo, M., Endo, J . , and Sakai, T.: Clinical Studies on the Effects of Prostaglandin A 2 on Water and Electrolyte Metabolism, Plasma Renin Activity and Plasma Aldosterone Concentration. Nalka Fokan 21(6): 191-204, 1974. Laborit, H . , and Valette, N. : The Action of Arachidonic Acid on Experimental Hypertension in the Rat. Chem. Biol. Interactions. 10: 239-246, 1975. Lonigro, A . J . , and Dawson, C .A.: Vascular Responses to Prostaglandin F2~ in Isolated Cat Lungs. Circ. Res. 36: 706-712, 1975. Madan, B . R . , Gupta, R . S . , and Madan, V.: Actions of Prostaglandins E 1 , E 2 , F1.~ and F2~ in Ouabain-Induced Arrhythraia and Maximal Electroshock Seizures. Indian J . Meal. Res. 62: 1647-1651, 1974. Malik, K.U. and McGiff, J . C . : Modulation by Prostaglandins of Adrenergic Transmission in the Isolated Perfused Rabbit and Rat Kidney. Circ. Res. 36: 599-609, 1975. Manthorpe, T. : Antihypertensive and Hypertensive Effects of the Kidney. Elucidated by Treatment with Medullary Transplants and with Blockade Either of the Reninangiotensin-System or of the Prostaglandin Biosynthesis. Acta Path. Microbiol. Scand. (A) 83: 395-405, 1975. McGiff, J . C . , Rskovitz, H . D . , and Terrag'no, N . A .: The Actions of Bradykinin and Eledoisin in the Canine Isolated Kidney: Relationships to Prostaglandins. Clin. Sci. Mol. Med. 49: 125-131, 1975. Ogletree, M . L . , Beardsley, A . C . , and Lefer, A.M.: Myocardial Actions of Prostaglandins in Isolated Cat Cardiac Tissue. Life Sci. 16: 1923-1930, 1975. Okada, F. and Nukada, T. : Mechanism of Antihypertensive Actions of Prostaglandin - Concentration of Prostaglandin in the Blood and Isomerase Activities in Hypertensive Patients. Jap. J . Clin. Med. 32: 2740-2743, 1974; (Japanese). Oken, D .E.: Role of Prostaglandins in the Pathogenesis of Acute Renal Failure. Lancet 1: 1319-1322, 1975. Otsuka, Y . , Saito, T . , Kiyono, M., Ono, I . , and Abe, K.: Hypotensive Action of Prostaglandin E 1. Jap. J . Clin. Med. 32: 2737-2740, 1974; (Japanese).

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Ozer, H., and Hollenbarg, N.K.: Renal Angiog~raphic and Hemodynamic Responses to Vasodilators. A Comparison of Five Agents in the Dog. Invest. Radio1. 9: 473-478, 1974. Papanicolaou, N . , Alexandre, J . M . , Bariety, J . , and Milliez, P.: Source, Nature, Role and Fate of the Prostaglandins Released Following the intravascular Volume Expansion of Anesthetized Rats. Pathol. Biol. (Paris) 23: 185-192, 1975; (French). Parratt, J . R . , and Sturgess, R .M.: Evidence that Prostaglandin Release Mediates Pulmonary Vasoconstriction Induced by E. Coli Endotoxin. J. Physiol. (Lond) 246: 79P-8OP, 1975. Pugsley, D . J . , Beilin, L . J . , and Peto, R.: Renal Prostaglandin Synthesis in the Goldblatt Hypertensive Rat. Circ. Res. (Suppl I) 36,37: 1-81-I-88, 1975. Rose, J . C . , Johnson, M., Ramwell, P.W. and Kot, P.A.: Cardiovascular and Platelet Responses in the Dog to the Monoenoic Prostaglandin Precursor Dihomo-Gamma-LinolenicAcid. Proc. Soc. Exp. Biol. Med. 148: 1252-1256, 1975. Rosenblum, W.I.: Constriction of Pial Arterioles Produced by Prostaglandin F2~. Stroke 6: 293-297, 1975. Satoh, S . , and Zimmerman, B.G.: Influence of the Renin-Angiotensin System on the Effect of Prostaglandin Synthesis inhibitors in the Renal Vasculature. Circ. Res. (Suppl I): 36,37: 1-89-I-96, 1975. Schulkens, B .A., and Steinbach, R.: Increase of Experimental Hypertension Following Inhibition of Prostaglandin Biosynthesis. Arch. Int. Pharmacodyn. Ther. 214: 328-334, 1975. Terragno, D . A . , Crowshaw, K., Terragno, N . A . , and McGiff, J . C . : Prostaglandin Synthesis by Bovine Mesenteric Arteries and Veins. Circ. Res. (Suppl I) 36, 37: 1-76-I-80, 1975. Toyama, T . , Murakami, K . , and Kuroda, M.: Diuretic Action of Prostaglandin A2 in Essential Hypertension - Relationship Between Body Water Composition and Diuretic Action of PGA2 . Jap. J. Clin. Med. 32: 2743-2748, 1974; (Japanese). Welch, K . M . A . , Spira, P . J . , Knowles, L., and Lance, J.W.: The Effect of Serotonin and Prostaglandins on Internal and External Carotid Blood-Flow Measured Simultaneously in the Monkey. Arch. Neurobiol. 37 (Suppl): 253-280, 1974.

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Wennmalm, A . , : Prostaglandin Release and Mechanical P e r f o m a n c e in the Isolated Rabbit Heart During Induced Changes i n the Internal Environment. Acta Physiol. Scand. 93: 15-24, 1975. Winkelmann, R.K. : The Pharmacology of Isolated Cutaneous Vascular Smooth Muscle. J. Dermatol. 1: 22-28, 1974. CHEMISTRY Amin, M. : Direct Quantitative Thin-Layer Chromatographic Determination of Prostaglandins A2, B 2 , E 2 , and F2ct. J. Chromatogr. 108: 313321, 1975. Bowler, J . , Mallion, K . B . , and Raphael, R.A.: Reduction of Prostaglandin Enone Intermediates with Aluminium Isopropoxide. Synth. Commun. 4: 211-213, 1974. Bundy, G.L.: The Synthesis of Prostaglandin Endoperoxide Analogs. Tetrahedron Lett. 24: 1957-1960, 1975. Clen, R., De Clercq, P., Van Hayer, D., Vandewalle, M. : Cyclopentanones. XII. A n Alternative Synthesis of Prostaglandins Involving Catalytic Hydrogenation of 2,3-DialkTI-4-Dihydroxy-2-Cyelopentenones. Bull. Soc. Chim. Belg. 04:203-206, 1975. Craln, P . F . , Desiderio, D.M., J r . , and McCloskey, J . A . ; Mass Spectrometry of Prostaglandins. Methods Enzymol. 35: 359-377, 1975. Esacr, A , and Bersohn, M.: A Program for Rapid and Automatic Functional Group Recognition. J. Chem. Soc. Perkin I: 2463-2470, 1974. Funk, M.O., Isaac, R . , and Porter, N.A.: Free Radical Cyclization of Unsaturated Hydroperoxides. J. Am. Chem. Soc. 97: 1281-1282, 1975. Godoy, L., Guzman, A . , and Muchowski, J.M.: Synthesis of l l - D e s o x y 12-Methylprostaglandins. Chem. Lett. 327-330, 1975. Grieco, P.A., Pogonowski, C.S., Nishizawa, M., and Wang, C.L,J.: 12-Methylprostaglandins Total Synthesis of 12-MethylPGF2~ c 12-MethyIPGE 2. Tetrahedron Lett. 30: 2541-2544, 1975. Guzman, A . , and Muehowski, J .M.: Synthesis of ll-Hydroxymethylprostaglandins. Tetrahedron Lett. 25: 2053-2056, 1975.

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Leovey, E .M.K., and Andersen, N.H.: Molecular Basis for Prostagiandin Potency. I. The Case for Biological Significance of Media Dependent Conformational Changes. J. Am. Chem. Soc. 97: 4148-4150, 1975. MalHon, K . B . , and Walker, E.R.H.: The Acetoxyfolvene Synthesis of Prostagiandins: A New, Versatile Synthesis of DL-PGF1ot, DLPGF2c6 DL-PGE 1 and DL-PGE 2 from a Common Intermediate. Synth. Commun. 5:221-226, 1975. Misiti, D., Caputo, A . , and Attanasi, O.: C-Alkylation of Thallium (I) Salts of Beta-Diketones: Synthesis of Cyclopentane-2-Oxo-1Heptanoic Acid. Farmaco. (Sci) 30: 3-7, 1975. Miyano, M., and Stealey, M.A. : Prostagiandins. VII. A Stereoselective Total Synthesis of Prostaglandin E 1. J. Org. Chem. 40: 1748-1755, 1975. Nidy, E . G . , and Johnson, R .A.: Synthesis of Metabolites of Prostagiandin F2~Resulting from Beta-Oxidation of the CarboXTlic Acid Side Chain. J . Org. Chem. 40: 1415-1420, 1975. Novak, L . , and Szantay, C .: Synthesis of a Prostanoid Intermediate. Synthesis: 353-354, 1974. Shimomura, H., Katsube, J . , and Matsui, M.: An Alternative Synthesis of Prostagiandins. Agr. Biol. Chem. 39: 657-661, 1975. Singh, E . J . , and Zuspan, F.P .: Silica Gel Impregnated Glass Fiber Paper Chromatography for the Separation and Identification of Prostaglandins. J. Chromatogr. Sci. 13: 188-189, 1975. Singh, E . J . , Zuspan, F . P . , and Moawad, A.: Spot Test for Detection of Prostaglandin E and F Compounds. Chromatographia 8: 290, 1975. Stork, G., Kowalski, C., Garcia, G.: A Route to Prostaglandins Via a General Synthesis of 4-Hydroxycyelopentenones. J. Am. Chem. Soc. 97: 3258-3260, 1975. Tanaka, T . , Kurozumi, S . , Toru, T . , Kobayashi, M., Miura, S . , and Ishimoto, S. : Regiospecific Acylation of Organocopper Enolates: A New Synthesis of 7-Oxoprostaglandins. Tetrahedron Left: 15351538, 1975.

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T r a v e r s o , G . , and Pirillo, D.: A Convenient Synthesis of (~)-8,12-Trmm9, 14-R ,S-Dihydroxyprostanoie Acid Methyl Ester. Farmaeo (SCI) 29: 883-885, 1974. Van Hooland, J . , De Clarcq, P . , and Vandewslle, M. ,: Cyclopentanones. XI. A Novel Preparation of a Prostanoid Synthon Starting from a 3-Alkyl-1,2,4-Cyclopentanetrione. Tetrahedron Lett: 4343-4346, 1974. CYCLIC AMP Bach, M.A.: Differences in Cyclic AMP Changes After Stimulation by Prostaglandins and Iseproterenol in Lymphocyte Subpopulations. J. Clin. Invest. 55: 1074-1081, 1975. Burgoat, P . , Labrie, F . , and Garneau, P.: Characteristics of Action of Prostaglandins on Cyclic AMP Accumulation in Rat Anterior Pituitary Gland. Can. J. Biochem. 53: 455-460, 1975. Champion, S . , Haye, B . , and Jacquemin, C.: Cholinergic Control b y Endogenous Prostaglandtns of cAMP Accumulation Under TSH Stimulation in the Thyroid. Febs. Lett. 46: 289-292, 1974. Ferre, F . , Breuiller, M., Cedard, L.: Human Placental cAMP Phospho-diesterase Activity Kinetic Properties and Sensitivity to Some Drugs and Hormones. Febs. Lett. 52: 295-299, 1975. Gemsa, D., Woo, C . H . , Webb, D., F u d e n b e r g , H . H . , and Schmid, R.: Erythrophagocytosis by Macrophages: Suppression of Heine Oxygenase by Cyclic AMP. Cell Immunol. 15: 21-36, 1975. Glasgow, A . , Polgal,, P . , Saporoschetz, I . , Kim, H., Rutenburg, A.M., Mannick, J .A., and Cooperband, S .R.: Phytohemagglutinin Stimulation of Human Lymphocytes. Failure to Detect an Early Increase in Cyclic AMP Concentration. CHn. Immunol. Immunopathol. 3: 353-362, 1975, Hickie, R . A . , J a n , S .H., and Katta, A.: Comparative Adenylate Cyclase Activities in Hornogonate and Plasma Membrane Fractions of Morris Hepatoma 5123TC (H). Cancer Res. 35: 596-600, 1975. Husey, M.M. and Tau, M.: Effect of 5~-Guanylyllmidodiphosphate on Prostaglandin- and Fluoride-Sensitive Adenylate Cyclase of Rabbit Red Blood Cells. Biochem. Biophys. Res. Commun. 64: 1363-1269, 1975.

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Klaeveman, H . L . , Conlon, T . P . , Levy, A . G . , and Gardner, J.D .: Effects of Gastrointestinal Hormones on Adenylate Cyclase ActiviW i n Human Jejunal Mucosa. Gastroenterology 68: 667675, 1975. Klee, W.A., Sharma, S .K., and Nirenberg, M.: Opiate Receptors as Regulators of Adanylate Cyelase. Life Sci. 16: 1869-1874, 1975. Levilliers, J . , Alsat, E . , Laudat, P . , and Cedard, L.: HormoneStiumlated cAMP Production in Human Placenta Perfused in Vitro. Febs. Left. 47: 146-148, 1974. Persianinov, L.S. Leonov, B . V . , Massal'Skaya, L.M., and Lomova, M.A.: Effect of Cyclic AMP on the Development of Sea Urchin Embryos. Bull. Exp. Biol. Med. 79: 188-190, 1975. Prasad, K . N . , Gilmer, K . N . , Sahu, S . K . , and Beckar, G.: Effect of Neurotransmitters, Guanceine Trtphosphate, and Divalent Ions on the Regulation of Adenylate Cyclase Activity in Maliguant and Adenosine Cyclic 3'"5'-Monophcephate-Induced "Differentiated" Neuroblastoma Cells. Cancer Res. 85: 77-81, 1975. Rosenthal, J.W. and Goldstein, S.: The Effect of Insulin on Basal and Hormone-Induced Elevations of Cyclic AMP Content in Cultured Human Fibroblasts. J. Cell Physiol. 85: 235-242, 1975. Roy, A . C . , and Collier, H . O . J . : Prostaglandins, Cyclic AMP and the Biochemical Mechanism of Opiate Agonist Action. Life Sci. 16: 1857-1862, 1975. Sahu, S .K., and Prasad, K.N.: Effect of Neurotransmitters and Prostaglandm E 1 on Cyclic AMP Levels in Various Clones of Neuroblastoma Cells in Culture. J. Neurochem. 24: 1267-1269, 1975. Sharma, S . K . , Nirenberg, M., and Klee, W.A.: Morphine Receptors as Regulators of Adenylate Cyclase Activity. Proc. Natl. Acad. Sci. USA 72: 590-594, 1975. Tomasi, V . , and Ferretti, E.: Proataglandin El-Sensitive Adenylate Cyclase of Rat Liver Plasma Membranes. Mol. Cell. Endocrinol. 2: 221232, 1975.

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PROSTAGLANDINS T r a b e r , J . , Reiser, G., Fischer, K . , and Hamprecht, B.: Measuremants of Adenoiaine 3': 5'-Cyclic Monophosphaie and Membrane Potential in Neuroblastoma X Glioma Hybrid Cells: Opiates and Adrenergic Agonists Cause Effects Opposite to Those of Prostaglandin E 1. Febs. Lett. 52: 327-332, 1975. Van Inwegen, R . G . , Strada, S . J . , and Robison, G.A.: Effects of Prostaglandins and Morphine on Brain Adenyl Cyclase. Life Sci. 16: 1975-1876, 1975. ENDOCRINE - METABOLISM Andersson, B . , and Ledsell, L.G.: Effects on Fluid Balance of I n t r e v e n tricular Infusions of Prostaglandin E 1. Acta Physiol. Scand. 93: 286-288, 1975. Boeynaems, J .M., Van Sande, J . , and Dumont, J .E .: Blocking of Dog Thyroid Secretion in Vitro by Inhibitors of Proataglandin Synthesis. Biochem. Pharmacol. 24: 1333-1337, 1975. C u r t i s - P r i o r , P .B.: Prostaglandins and Obesity. Lancet 1: 897-899, 1975. Markov, K.M., Bankuva, V . V . , Kutcherenko, A.G.: Effect of Prostaglendin E2 on the Biosynthesis of Corticosteroids. Fiziolhk Zh SSSR 8echenova 60: 635-639, 1974; (Russia.n). Davis, S .L., and Anfinson, M.: Dose-Response Influence of Prcetaglandin E1 and Somatostaiin on Plasma Levels of Growth Hormone, Prolactin and Thyrctropin in Sheep. J. Anita. Sci. 41: 172-177, 1975. F r a n k l i n , R . B . , and Tashjian, A . H . , J r . : Intravenous Infusion of Prostaglandin E2 Raises Plasma Calcium Concentration in the Rat. Endocrinology 97: 240-243, 1975. Polonovski, J . , Bard, D., Bereziat, G.: Modifications of Synthesis of Prostaglandins in Rat Liver by Insulin and Glucagon. C .R. Soc. Biol. (Paris) 168: 1208-1210, 1974; (French). Richman, R . , Park, S . , Akbar, M., Yu~ 8 . , and Burke, G.: Regulation of Thyroid Ornithine Decarboxylase (DDC) by Thyrotropin. I. The Rat. Endocrinology 96: 1403-1412, 1975. Sacca, L., Perez, G . , RenEo, F . , Pascucci, I . , Condorelli, M.: Reduction of Circulating Insulin Levels During the Infusion of Different Prostaglaudins in the Rat. Acta Endocrinol (KBH) 79: 266-274, 1975.

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Spat, A . , and Jozan, S .: Effect of Prostaglandin E 2 and A 2 on Steroid Synthesis by the Rat Adrenal Gland. J . Endocrinol. 65: 55-63, 1975. T u c k e r , H . A . , Vines, D. T . , Stellflug, J . N . , and Convey, E. M.: Milking, Thyrotropin-Releasing Hormone and Prostaglandin Induced Release of Prolactin and Growth Hormone in Cows. Proc. Soc. Exp. Bio. Med. 149: 462-469, 1975. GASTROINTESTINAL Bennett, A . , Elley, K. G . , and Stoekley, H. L.: The Effects of Prostaglandins On Guinea-Pig Isolated Intestine and T h e i r Possible Contribution To Muscle Activity and Tone. Br. J . Pharmacol. 54: 197-204, 1975. Bowen, J . C . , Kud, Y. J . , Pawlik, W., Williams, D ., Shanbour, L. L., and Jacobson, E. D. Electrophysiological Effects of Burimamide and 16,16-Dimethyl Prostaglandtn E 2 on the Canine Gastric Mucosa. Gastroenterology 68:1480-1484, 1975. Cheung, L. Y . , J u b i z , W., Torma, M. J . , and Frailey, J . : Effects of Aspirin on Canine Gastric Prostaglandin Output and Mucosal Permeability. S u r g . Forum 25: 407-409, 1974.

Grubb, M. N . , and Burk8, T. F.: Selective Antagonism of the Intestinal Stimulatory Effects of Murphine by Isoproterenol, Prostaglandin E1 and Theophylline. J . Pharmacol. Exp. T h e r . 193: 884-891, 1975. Hazra, J . : Evidence Against Prostaglandin E Having a Physiological Role in Acetylcholine Liberation from Auerbach's Plexus of Guinea-Pig Ileum. Experientia 31: 565-566, 1975. Kaminski, D. L . , Ruwart, M., and Willman, V. L.: The Effect of Prostaglandin A1 and E 1 on Canine Hepatic Bile Flow. J . Surg. Res. 18: 391-397, 1975. Karim, S. M. M., and Fung, W. P.: Effect of 15 (R) 15-Methyl Prostaglandin E 2 on Gastric Secretion and a Preliminary Study on the Healing of Gastric Ulcers in Man. Int. Res. Commun. Syst. Med. Sci. 3: 348, 1975. Newman, A . , De Moraes-Filho, J . P. P . , Philippakos, D . , and Misiewicz, J . J . : The Effect of Intravenous Infusions of Prostaglandins E 2 and F 2 ~, on Human Gastric Function. Gut. 16: 272-276, 1975. Nylander, B. and Andersson, S.: Gastric Secretory Inhibition by Two 16-Methylated Analogs of Prostaglandin E 2 Given Intragastrically to Patients with Duodental Ulcer Disease. Scand. J . Gastroenterol. 10: 217-220, 1975.

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Robert, A . , and Yankee, E. W. : Gastric Antisecretory Effect of 15 (R)-15Methyl PGE 2 , Methyl Ester and of 15 (S)-15-Methyl PGE 2 , Methyl Ester. Proc. Soc. Exp. Biol. Med. 148:1155-li58, 1975. HYPERSENSITIVITY - IMMUNOLOGY Anderson, C. B . , Newton, W. T . , and Jaffe, B. M.: Circulating Prostagiandin E and Allograft Rejection. Transplantation 19: 527-528, 1975. Anderson, C. B . , and Jaffe, B. M.: Circulating Prostaglandin E. and Canine Skin Allografts. Surg. Forum 25: 287-289, 1974. Blackham, A . , and Owen, R. T . : Prostaglandin Synthetase Inhibitors and Leucocytic Emigration. J . Pharm. Pharmacol. 27: 201-203, 1975. Chang, W. C . , Murota, S . , and Tsurufuji, S .: Contents of Prostagiandin E in the Exudate of Rat Carrageenin Granuloma. Jap. J . Pharmacol. 25: 219-221, 1975. Cho, B. D . , and Shim, B. S .: The Effects of Various Prostagiandins and Insulin on Rabbit Serum Haptogiohin Level. J . Cath. Med. Co11. (Seoul) 26:1-6, 1974. Denko, C. W. : Anti-Prostagiandin Action of Colchicine. Pharmacology 13: 219-227, 1975. Denko, C. W. : Effect of Prostaglandins in Urate Crystal Inflammation. Pharmacology 12: 331-339, 1974. Di Rosa, M., Capasso, F . , and Verde, P.: Mechanism of Action of Nonsteroidal Anti-Inflammatory Durgs. Riv. Farmacol. Ter. 5: 255A-270A, 1974; (Italian) Glatt, M., Graf, P . , and B r u n e , K.: Effects of Colchicine in Acute Inflammation. Experientia 31: 728, 1975. Higgs, G. A . , McCall, E . , and Youlten, L. J . F.: A Chemotactic Role for Prostagiandins Released From Polymorphonuclear Leucocytes During Phagocytosis. Br. J . Pharmacol. 53: 539-546, 1975. Liebig, R , , B e r n a u e r , W., and Peskar, B. A.: Prostagiandin, Slow-Reacting Substance, and Histamine Release From Anaphylactic Guinea-Pig Hearts, and Its Pharmacological Modification. Naunyn-Schmiedebergs Arch. Pharmacol. 289: 65-76, 1975. Moncada, S . , F e r r e i r a , S. H . , and Vane, J . R.: Inhibition of Prostagiandin Biosynthesis as the Mechanism of Analgesia of Aspirin-Like Drugs in the Dog Knee Joint. Eur. J . Pharmacol. 31: 250-260, 1975.

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Plescia, O. J . , Smith, A. H . , and Grinwich, K.: Subversion of Immune System b y Tumor CeiLs and Role of Prostaglandina. Proc. Natl. Acad. Sci. USA 72:1848-1851, 1975. Robinson, D. R . , McGhdre, M. B . , and Levine, L.: Prostaglandins in the Rheumatic Diseases. Ann. N'Y. ACAD. Sci. 256: 318-329, 1975. Robinson, H. J . , J r . , and Granda, J. L.: Prostaglandins in Synovial InflRmmatory Disease. Surg. Forum 25: 476-477, 1974. Smith, M. J . H . , Ford-Hutchinscm, A. W., and Elliott, P. N. C. : Prostaglandins and the Anti-Ivflmmmatory Activities of Aspirin and Sodium Sslicylate. J. Pharm. Pharmacol. 27: 473-478, 1975. Teitz, C. C . , and Chrisman, O. D.: The Effect of Salioylate and Chloroquine on Prostaglsndin-Induced Articuisr Damage i n the Rabbit Knee. Olin. Orthop. Relat. Res: 264-274, 1975. NERVOUS SYSTEM Burnstock, G., Cocks, T . , Paddle, B . , and Staszewska-Barczak, J . : Evidence that Prostaglandin 16 Responsible for the 'Rebound Contraction' Following Stimulation of Non-Adrenergic, Non-Cholinergic ( ' P u r i n e r g i c ' ) Inhibitory Nerves. Eur. J . Pharmaeol. 31:360-362, 1975. Clark, W. G . , and Cumby, H. R. : The Antipyretic Effect of Indomethacin. J . Physiol. (Lond) 248: 625-638, 1975. Cocearfi, F . , and Viti, A.: Responses of Spinal Neurons to Iontophoretically Applied Prostaglandin E1 i n the Frog. Can. J . Physiol. Pharmacol. 53: 273-284, 1975. Collier, H. O. J . , F r a n c i s , D. L . , McDonald-Gibson, W. J . , Roy, A. C., and Saeed, S. A.: Prostagisndins, Cyclic Amp and the Mechanism of Opiate Dependence. Life Sci. 17: 85-90, 1975. Cranston, W. I . , Hellon, R. F . , and Mitchell, D.: Fever and Brain Prostaglandin Release. J. Physiol. (Lond) 248: 27P-29P, 1975. Frame, M. H., and Hedvist, P.: Evidence for Prostaglandin Mediated Prejunctional Control of Renal Sympathetic Transmitter Release and Vascular Tone. Br. J. Pharmacol. 64: 189-196, 1975. Gryglewski, R. J . , Szczeklik, A . , and Bieron, K.: Morphine Antagonises Prostaglandin El-Mediated Inhibition of Human Platelet Aggregation. Nature (Lond) 256: 56-57, 1975.

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PROSTAGLANDINS Haavik, C. O., Crowshaw, K . , Collins, F. G., and Hardman, H. F.: Relationship of Prostaglandins and Fever to the Hypothermic Action of Delta 9-Tetrahydrocannabinol. Proc. Syrup. Temp. Regul. Drug Act, Paris 1974, Karger, Basel: 310-318, 1975. Jell, R. M. : Amine-Prostaglandin Modulation of Activity of Thermo-Regulatory Neurones. Proc. Syrup. Temp. Regul. Drug Act, Paris 1974, Karger, Basel: 119-123, 1975. Kimishima, K . , Tanabe, K . , Yamasaki, M., Kinoshita, Y . , Tamaki, H., Hanada, Y . , Shimabukoro, T . , and Fukushima, H. : Action of Prostaglandin F 2 ot on the Central Nervous System. Yonago Igaku Zasshi 25: 281-295, 1974; (Japanese). Komiskey, H. L . , and Rudy, T. A. : The Involvement of MethysergideSensitive Receptors and Prostaglandins in the Hyperthermia Evoked by 5-HT in the Cat. Ras. Commun. Chem. Pathol. Pharmacol. H: 195-208, 1975. Laborit, H . , Thuret, F . , and Laurent, J .: The Effect of Arachidunic Acid on the Motor ActiviW of the Mouse. Agressologie 14: 391-385, 1973; (French). Laburn, H., Woolf, C. J . , Willies, G. H., Rosendorff, C.: Pyrogen and Prostaglandin Fever in the Rabbit-H: Effects of Noradrenaiine Depletion and Adrenergic Receptor Blockade. Neuropharmacology 14: 405411, 1975. Madan, B. R . , and Khanna, N. K.: Effect of Prostaglandins (PG) E1 and F 2 on the AceWlcholine Concentrations of Rat's Brain and Heart. Indian J . Med, Res. 62:1757-1759, 1974. Neufeld, A. H., and Page, E. D. : Regulation of Adrenergic Neuromuscular Transmission in the Rabbit Iris. Exp. Eye Res. 20: 549-561, 1975. Robinson, S. M., and Mager, M.: 2-Deoxy-D-Glucose Inhibition of Prostaglandin E1 Hyperthermia and Yeast Fever in Mice. J. Appl. Physiol. 38: 1092-1094, 1975. Pittman, Q. J . , Veale, W. L . , and Cooper, K. E.: Temperature Responses of Lambs After Centrally Injected Prostaglandins and Pyrogens. Am. J. Physiol. 228: 1034-1038, 1975. Rudy, T. A . , and Viswanathan, C. T.: Effect of Central Cholinergic Blockade on the Hyperthermia Evoked by Prostaglandin E1 Injected Into the Rostral Hypothalamus of the Rat. Can. J. Physiol. Pharmacol. 53: 321-324, 1975.

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Wcolf, C. J . , Willies, G. H . , Laburn, H . , and Rosendorff, C.: Pyrogen and Prostsghmdin F e v e r in the Rabbit-h Effects of Salicylate and the Role of Cyclic AMP. Neuropharmaeology 14: 397-403, 1975. REPRODUCTION - CLINICAL Andermm, G. G . , and Schooley, G. L.: Comparison of Uterine Contractions in Spontaneous and Oxytocin- or PGF2<~-Induoed Labors. Obstet Gynecol (NY) 45:284-286, 1975. Bostofte, E . , Stakemann, G . , and Stocklund, K. E.: A Comparison of Termination of Pregnancies in the 2rid T r i m e s t e r Induced by intraanmiotic Injection of Hypertonic Saline, Proslaglandin F2<~ or Both Drugs. Acta. Obstet. Gynecol. Scand. (Suppl.) 37: 47-50, 1975. B r e n n e r , W . E . , Dingfelder, J . R . , StatwovsK~, L. G . , Kumarasamy, T . , and Grimes, D. A.: Lntramuscular Administration of 15(S) 15 Methyl Prostaglandin E 2 Methyl Ester of Abortion: A Comparison of Two Dose Schedules. Fertil. Steril 26: 369-379, 1975. B r e n n e r , W. E . , Hendricks, C. H . , F i s h b u r n e , J . I . , Dingfelder, J . R . , and S t r a u r o v s k y , L. G.: Phase H Clinical Trials of Prostaglandin F2~ in: "Endocrine-MetaboLic D r u g s , " FG McMahon, Futura Publ. Mount Kiseo, 6: 65-90, 1975. Cheng M. C. E . , Darim, S, M. M . , and Ratnam, $. S.: Preoperative Cervical Dilatation with 15 (S) 15 Methyl Prostaglandin E 2 Methyl Ester i n F i rs t Trimester NulLiparae- a Double BHne Study. Contraception 12: 59-67, 1975. Craft, I.: Intra-Anmiotic Urea and Low-Dose Prostaglandin E 2 for MidTrimester Termination. Lancet 1:1115-1116, 1975. Dingfelder, J . R . , B r e n n e r , W. E . , Hendricks, C. H . , and Staurovsky, L. G.: reduction of Cervical Resistance by Prostaglanclin Suppositories Prior to Dilatation for Induced Abortion. Am. J . Obstet. Gynecol. 122: 25-30, 1975. Gowenlock, A. H., Taylor, D. S., and Sanderson, J. H.: Biochemical and Haematological Changes During the Induction of Labour at Term with Oxytocin, Prostaglandin E 2 and Prostaglandin F2
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Lange, A . P . , S e c h e r , N. J . , and Pedersen, G. T . : Comparison of ExtraAnmioflc Administration of PGF2aL, 0.9 Percent Saline, and 20 Percent Saline Followed by Oxytocin for Therapeutic Abortion. Acta. Obstet. Gynecol. Scand. (Suppl.) 37: 61-66, 1975. IAndmark, O., Zador, G . , and Nilsson, B. A.: The Induction of Labour with Prostaglandin F2~by Intravenous Infusion. Acta, Obstet. Gynecol. S t a n d . (Suppl.) 37:17-26, 1975. Lindmark, G . , Zador, G., and Nilsson, B. A.: The Induction of Labour with Prostaglandin F ~ by Intravenous Infusion. II. a Comparison of Fetal and Maternal Acid-Base Values with Those Found in OxTtocin Induced Labour and in Spontaneous Labour. Acta. Obstet. Gynecol. Scand. (Suppl.) 37: 27-34, 1975. Lippert, T. H . , and Mudly, T .: Indueel Abortion with Prostaglandin E 2 and F2~ Gel. Gynaekol. Rundsch. 14:234-235, 1974: (German). Martin, J. N . , Bygdeman, M., Leader, and Wiqvist, N.: Early Second Trimester Abortion by the Extra-Amniotie Instillation of Rivanol Solution and a Single PGF2~Dose. Contraception 11: 523-531, 1975. Mtwzouk, A. F. : Oral and Intravenous Prostaglandin E 2 in Induction of Labour• Br. J. Clin. Pract. 29: 68-70, 1975. Mehta, A.: Prostaglandins as Abortffacients. J. Obstet. Gynaecol. India 24: 533-544, 1974. Pasetto, N.: Prostaglandin PGF2~in Induction of Labor. Minerva. Ginecol. 27: 85-93,1975; (Italian). Nielsen, K. R . , Gregersen, E . , Larsen, J . F . , and Olsen, C. E. : Prostaglandin F2~and Oxytocin Compared with Hypertonic Saline and Oxytocin for the Induction of Second Trimester Abortion. Acta. Obstet. Gynecol. Scand. (Suppl.) 37: 57-60, 1975. Nyberg, R.: Intraamniotic Administration of Prostaglandin F2c~for Therapeutic Abortion. Acta. Obstet. Gynecol. Scand. (Suppl.) 37: 41-46, 1975. Obel, E • B . , and Larsen, J. F. : A Study of Comparative Efficacy of Oral Prostaglandin E 2 as Liquid Formulation and Tablets for Induction of Labour. Acta. Obstet. Gynecol. Scand. (Suppl.) 37: 35-37, 1975. PhiLlips, L. L. : F i b r i n Monomer as a Test for Intravascular Coagulation. Obstet. Gynecol. (NY) 45:124-128, 1975.

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Romero-Salinas, G., Ramirez-Jimenez, D., Garcla-Pena, J . , Rutz-Velasso, V., and Bravo-Sandoval, J . : Effect of Prostaglandin F 2 Alpha on the Contractility of the Human Pregnant Uterus. Gineeol. Obstat. M e x . 35:627-656, 1974; (Spanish). Shearman, R. P . , Lyneham, R. C., Walsh, J. C., Itzkowie, D., and Shutt, D. A. : Electroeneephalographie Chanfes After Intra-Amnlotle Proetaglsndin F2c~and Hypertonie Saline. Br. J . Obstet. Gynasool. 82: 314-317, 1975. Slaughter, L., and Ballard, C. A.: Midtrtmester Abortion with Intramuseulaz Injection of 15 - Methyl - Prostagelsndin F2~. Contraception 11."535-§40, 1975. Waldron, K. W., and Waiters, W. A. W.: Pr~staflandin F~:~Givan by Continous Transcervical Extra-Amniotic Infuation Combined with Intranseervieal Ocytoein Infusion for Therapeutic Termination of Mid-Trimester Pregnancies. Med. J. Aust. h 525-527, 1975.

Walker, S. M., FLint, A. P. F . , and Turnboll, A. C.: Rate of Fall in Plasma Progesterone and Time to Abortion Following lntra-Anmiotie Injection of Prostaglandtn F2st, with or withoutUrea, in the Second Trimester of Human Pregnancy. Br, J. Obstet. Gynaevol. 92: 498-492, 1975. Widholm, O., Kajanoja, P . , and Johansson, E. D. B.: Serum Levels of Oestradiol and Progesterone During Administration of Prostaglsndin F2,1for Induction of Abortion and Labour. Acta. Ohstet. Gynecol. Scand. 54: 135-139, 1975. Zahn, V., and Johannigmann, J . : Prostaglsndin F ~ a s a Method of Choice for Interruption of Pregnancy. Geburtshilfe Frauenheilkd. 35: 203-210, 1975; (German). Berwyn-Jones, M. D., and Irvine, C. H. G.: Induction of Luteolysis and Destrus in Mares with s Synthetic Prostaglsndin Analogue (ICI 81008). N. Z. V e t . J . 22:107-110, 1974. Chaudhury, M. R. : The Effect of Drugs on Implantation in Rats with an Intrauterine Device in One Horn of the Uterus. J. Reprod. Fertil. 42: 571-573, 1975. Cornwell, J. C., Godke, R. A . , and Kreider, J. L. : Induction of Estrus in Mares after Foal Heat with PGF2¢(. Livest. Prod. Day, La. State Univ. Anita. Sci. Dep. 15: 279-281, 1975. Czeranowski, R.: Influence of Prostaglandins F 2 and E1 on Vaginal Contractility. Obstet. Gynecol. (NY) 45: 628-631, 1975.

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Dobson, H., Cooper, M . J . , and Furr, B . J . A . : Synchronization of Oestrus with ICI 79,939, an Analogue of PGF2~, and Associated Changes in Plasma Progesterone, Oestrediol-17 Beta and LH in Heifers. J. Reprod. Fertil. 42: 141-144, 1975. Edqvist, S . , Einarsson, S . , and Gustafsson, B. : Effect of Prostaglandin F2.~on Sperm Transport in the Reproductive Tract of the Ewe. Acts Vet. Scand. 16: 149-151, 1975. Erickson, G .F., and Ryan, K .J. : The Effect of LH/FSH, Dibutyryl Cyclic AMP, and Prostaglandins on the Production of Estrogens by Rabbit Granulosa Cells in Vitro. Endocrinology 97: 108-113, 1975. Flint, A . P . F . , Forsling, M.L., Mitchell, M.D., and Turnbull, A.C.: Temporal Relationship Between Changes in Oxytocin and Prostaglandin F Levels in Response to Vaginal Distension in the Pregnant and Puerperal Ewe. J . Reprod. Fertil. 43: 551554, 1975. Godke, R . A . , Hahn, S . , Bercovitz, A . B . , Boulward, R . F . , and Kreider, J .L.: Induced Lambing with Prostaglandin F2~ in Domestic Ewes. Livest. Prod. Day, LA State Univ. Anita. Sci. Dep. 15: 290-292, 1975. Goodeaux, L . L . , Bercovitz, A . B . , Reynolds, W.L., Kreider, J . L . , and Godke, R.A.: The Use of Prostaglandins for induction of Parturition in the Beef Female. Livest. Prod. Day, LA State Univ. Anim. Sci. Dep. 15: 151-154, 1975. Green, K., and Hagenfeldl, R.: Prostagtandins in the Human Endometrium. Gas Chromatographic-Mass Spectrometric Quantitation Before and After IUD Insertion. Am. J. Obstet. Gynecol. 122: 611-614, 1975. Hallford, D.M., Wettemann, R . P . , Turman, E . J . , Omtvedt, I . T . , Kreider, D . L . , and Welty, S.D.: The Influence of Prostaglandin F2~ on Estrous Cycle Length and the Induction of Parturition in Swine. Okla. Agr. Exp. Sta. Mist, Publ. 92: 187-191, 1974. Hawk, H.W., and Conley, H.H.: Altered Motility of Myometrium from Estrous Ewes After the Regulation of Estrus with Proffestsgen or Prostagtandin. Therioffenology 2: 37-46, 1974. Hendricks, D.M., and Handlin, D.L.: Induction of Parturition in the Sow with Prostagtandin F2~. Theriogenology 1: 7-14, 1974.

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H u n g , N . S . , s n d Mohailal, M.E.: Abortifacient Effect of 20 P e r c e n t NaCL Solution and P r o s t a g l a n d i n F2~bY Intra-Amniotic Administration in the Rat. J . Gynecol. Obstet. Biol. Reprod. 3: 1169-1188, 1974; (French). J a n s o n , P . O . , A l b r e c h t , I . , and A h r e n , K. : Effects of P r o s t a g l a n d i n F2 ~ on Ovarian Blood Flow and Vascular Resistance i n the Pseudop r e g n a n t Rabbit. Acts E n d o c r i n o l . (KBH) 79: 337-350, 1975. King, G • L . , and R o b e r t s o n , H.A.: A Two Injection Schedule with P r o s t a g l a n d i n F2xfor the Regulation of the Ovulatory Cycle of Cattle. TheriogenologT 1: 123-128, 1974. Lavoie, V . A . , Poncelet, G . R . , Hart, D . K . , Soliday, O . L . , Lambert, P . W . , and Moody, E . L . : Effect of P r o s t a g l a n d i n F2~(on the Estrous Cycle, Corpora Lutea and P r o g e s t e r o n e Levels of Hysterectomized Cows. J. Anita. Sci. 41: 166-171, 1975. Leaver, J . D . , G l e n c r o s s , R . G . , and Pope, G . S . : Fertility of F r i e a i a n Heifers After Luteolysis with a P r o s t a g i a n d i n Analogue (ICI 80996). Vet. Rec. 96: 383-384, 1975. Manns, J . G . , Newcomb, R . , and Rowson, L . E . A . : Effect of Cervical Stimulation on PGF2~tRelease into Uterine Vein Blood of Heifers. Vet. Rec. 96: 384-385,1975. Neal, P . , Baker, T . G . , McNatty, K . P . , and Scaramuzzi, R . J . : Influence of P r o s t a g i a n d i n s and Human Chorionic Gonadotrophin on P r o g e s t e r o n e and Oocyte Maturation in Mouse O v a r i a n Follicles Maintained in Organ C u l t u r e . J . Endocrinol. 65: 19-25, 1975. Nov'y, M . J . , Thomas, C.L. and Lees, M.H.: Uterine Contractility and Regional Blood Flow Responses to Oxytocin and P r o s t a g l a n d i n E 2 in P r e g n a n t T h e s u s Monkeys. Am. J. Obstet. Gynecol. 122: 419-433, 1975. Ojeda, S . R . , Wheaton, J . E . , and McCann, S .M.: P r o s t a g i a n d i n E 2 - I n d u c e d Release of Luteinizing l t o r m o n e - R e l e a s i n g Factor (LRF). Neuroendocrinology 17: 283-287, 1975. P a r n h a m , M . J . , S n e d d o n , J . M . , and Williams, K . I , : Evidence for a Possible Foetal Control of P r o s t a g l a n d i n Release from the P r e g n a n t Rat Uterus in Vitro. J . E n d o c r i n o l . 65: 429-437, 1975. Paton, D . M . , and J o h n s , A.: Effects of P r o s t a g i a n d i n E 2 and Indomethacin on Responses of the Isthmus of Rabbit Oviduct to N o r e p i n e p h r i n e and T r a n s m u r a l Stimulation. Res. Commun. Chem. Pathol. Pharmacol. 11: 15-24, 1975.

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Persaud, T.V.N.: Prolongation of Pregnancy and Abnormal Fetal Development in Rats Treated with Indomethacin. Int. Res. Commun. Syst. (Med. Sci.) 3: 300, 1975.

Pexton, J . E . , F o r d , S . P . , Wilson, L . , J r . , B u t c h e r , R . L . , and I n s k e e p , E . K . : P r o s t a g l a n d i n s F in Uterine T i s s u e and Venous Plasma of Ewes with I n t r a u t e r i n e Devices. J . Anita. Sci. 41: 144153, 1975. P e x t o n , J.E., Weems, C.W., and Inskeep, E.K.: Prostaglandins F in Uterine Venous Plasma, Ovarian Arterial and Venous Plasma and in Ovarian and Luteal Tissue of Pregnant and Nonpregnant Ewes. J. Anita. Sci. 41: 154-159, 1975. Poulos, A., Brown-Woodman, P.D.C., White, I.G., and Cox, R.I.: Changes in Phospholipids of R a m Spermatozoa During Migration Through the Epididymis and Possible Origin of Prostaglandin F 2 in Testicular and Epididymal Fluid. Biochim. Biophys. Acta 388: 12-18, 1975. Rao, B. , and Karim, S .M .M. : In Vitro Effects of ICI 81008, a PGF2~ ' Analogue, on the H u m a n Corpus Luteum. Int. Res. Commun. Med. Sci. 3: 339, 1975.

Saksena, S.K., Lau, I.F., Bartke, A., and Chang, M.C.: Effect of Indomethacin on Blood Plasma Levels of LH and Testosterone in Male Rats. J. Reprod. Fertil. 42: 311-317, 1975. Saksena, S.K., Lau, I.F., and Chang, M.C.: Induction of Midterm Abortion in Rabbits and Hamsters with Silastic-PVP Tubes Containing Prostaglandins E 2 and F2~~. Contraception 11: 479-487, 1975. Sato, T., Jyujo, T., Kawarai, Y., andAsai, T.: Changes inLH-Releasing Hormone Content of the Hypothalamus and Electron Microscopy of the Anterior Pituitary After Prostaglandin E 2 Injection in Rats. Am. J. Obstet. Gynecol. 122: 637-641, 1975.

S p i l m a n , C . H . , and Roseman, T .J .: Luteolytic and Abortifacient Effects in R h e s u s Monkeys of Silicone Vaginal Rings Containing 15(S)15M e t h y l - P r o s t a g l a n d i n F2~(Methyl E s t e r . Contraception 11: 409418, 1975. Szontagh, F.E., Falkay, G., Herczeg, J., and Bartfai, G.: Investigations of Amniotic Fluid After Intra-amnial Application of Prostaglandin F 2 x. Z. Geburtshilfe Perinatol. 178: 429-432, 1974; (German).

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Taya, K . , Sato, T . , l g a r a s h i , M.: Effect of Prostaglandin F2~upon Ovulation and LH, GSH and Prolactin Secretion in Chlorpromazine Blocked Rats. Endocrinol. J a p . 22: 131-136, 1975. Tochmann-Duplessis, H . , Hiss, D . , Mottot, G . , and Rosner, I.: Effects of Prenatal Administration of AceWlsalicylic Acid in Rats. Toxicology 3: 207-211, 1975. Umo, I . : Effect of Prostaglandin F2~on the Ultrastructure and Function of Sheep Corpora Lutea. J . Reprod. F e r t i l . 43: 287-292, 1975. V a s t i k - F e r n a n d e z , J . , Gimeno, M . F . , Lima, F . , and Gimeno, A , L . : Spontaneous Motility and Distribution of Prostaglandins in Different Segments of Human Fallopian Tubes. Am. J. Obstet. Gynecol. 122:663-669, 1975. Wishart, D .F. : Synchronisation of Oestrus in Cattle Using a Potent Progestin (SC21009) and PGF2ct. Theriogenology 1: 87-90, 1974. Witherspoon, D.M., Lamond, D . R . , Thompson, F . N . , and Stevenson, W.: Efficacy of a Prostaglandin Analogue in Reproduction in the Cycling Mare, TheriogenologT 3: 21-30, 1975. RESPIRATORY Grodzinska, L . , Panczenko, B . , and G r y g l e w s k i , R . J . : Generation of Prostaglandin E-Like Material by the Guinea-Pig Trachea Contracted by Histamine. J. Pharm. Pharmacol. 27: 88-91, 1975. T r a v a n i , J . , and Melville, G.N.: Mucociliary Activity in the Respiratory Tract as Influenced b y Prostaglandin E 1. Respirations; Int. Rev. of Thorac. Dis. 32:305-315, 1975. Kreisman, H . , Van de Wiel, W., and Mitchell, C .A.: Respiratory Function During Prostaglandin-Induced Labor. Am. Rev. Resp. Dis. 111: 564-566, 1975. Smith, A . P . , Cuthbert, M . F . , and Dunlop, L . S . : Effects of Inhaled Prostaglandin E 1 , E 2 , and F2~on the Airway Resistance of Healthy and Asthmatic Man. Clin. Sci. Mol. Med. 48: 421430, 1975. S t r a n d b e r g , K . , and Hedqvist, P. : Airway Effects of Slow Reacting Substance, Prostaglandin F2~tand Histamine in the GuineaPig. Acta Physiol. Scand. 94: 105-111, 1975.

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W a s s e r m a n , M . A . ; Bl,o ~ c h e p u l m o ~ a r y R e s p o n s e s to Pr(mtsghtndin ¥2ct, Histamine a n d A e e t y l e h o l i n e in the Dog. E u r . J . Ph815nseol. 32: 146-155, 1975. REVIEWS CendeLla, R . J . : P r o s t a g l a n d i n s a n d Male R e p r o d u c t i v e P h y s i o l o g y in: " A d v . S e x Horm. R e s . ," J . A . Thomas a n d R . L . 8 i n g h a l , U n i v e r s i t y P a r k P r e s s , Baltimore 1: 325-358, 1975. C r a i g , G.M. : P r o s t a g l a n d i n s in R e p r o d u c t i v e P h y s i o l o g y . P o s t g r a d . Med. J . 51: 74-84, 1975. G o l d y n e , M.E .: P r o s t a g l a n d i n s a n d Cutaneous IvfiAmmation. J . I n v e s t . Dermatol. 64: 377-385, 1975. G u t i e r r e z - C e r n o s c k , R . M . , L e v i n e , L . , a n d G j i k a , H.: Immunology of P r o s t a g l a n d i n s . Methods Enzymol. 35: 282-298, 1975. Holderoft. A. : P r o s t a g l a n d i n s - A R e v i e w . A n a e s t h . I n t e n s i v e C a r e 3: 105113, 1975. Lee, J . B . : Renal P r o s t a g l a n d i n s and the A n i t h y p e r t e n s i v e E n d o c r i n e F u n c t i o n . Med. Clin. North Am. 59: 713-733, 1975. O b e n b e r g e r , J . : P r o s t a g l a n d i n s a n d T h e i r Effect in the E y e . C e s k . Optalmol. 30: 452-463, 1974; ( C z e c h ) . R u s s e l l , P . T . , E b e r l e , A . J . , a n d C h e n g , H . C . ; T h e P r o s t a g l a n d i n s in Clinical Medicine. A D e v e l o p i n g Role for the Clinical Chemist. Clin. Chem. 21: 653-666, 1975. Samaja, B . A . , and R i g a g n o l i , A. : P r o s t a g l a n d i n s in Human R e p r o d u c t i o n

and T h e i r Clinical A p p l i c a t i o n in O b s t e t r i c s and G y n e c o l o g y . Minerva Ginecol. 27 25-33, 1975; ( I t a l i a n ) . Shaw, J .O. and Moser, K.M. : The Current Status of Prostaglandins and the Lungs. Chest 68: 75-80, 1975. Silver, M.J., and Smith, J .B. : Minireview: Prostaglandins as Intracellular Messengers. Life Sci. 16: 1635-1648, 1975. Sondergaard, J.: Prostaglandins in Normal and Pathological Skin. J. Cut. Pathol. 1: 275-290, 1974.

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Vane, J . R . , and McG/ff, J .C.: Possible Contributions of Endogenous Prostaglandins to the Control of Blood Pressure. Circ. Res. (Suppl. I) 36,37:1-68-I-75, 1975. Williams, K . I . , and V a n e , J . R . : Inhibition of Uterine Motility: The P o s s i b l e Role of the P r o s t a g i a n d i n s and A s p i r i n - L i k e D r u g s . P h a r m a c o l . T h e r . (13)1: 89-113, 1975. Wiqvist, N . , B y d g a m a n , M . , G r e e n , K . , and L u n d s t r o m , V. : Endogenous P r o s t a g l a n d i n s and the Initiation of L a b o r . Acta Obstet. Gynecol. S c a n d . ( S u p p l . ) 37: 7-16, 1975. Z u r i e r , R . B . : P r o s t a g l a n d i n s . In: "Mediators of Inflammation", G. Weissman Plenum P r e s s , New York: 163-180, 1974. MISCELLANEOUS A d o l p h e , M . , G i r o u d , J . P . , T i m s i t , J . , F o n t a g n e , J . , and Lechat, P . : Action of P r o s t a g l a n d i n A 2 on the Proliferation and Morphological Differentiation of Moose Neuroblastoma Cell C u l t u r e . Cr. Soc. Biol. ( P a r i s ) 168: 694-698, 1974; ( F r e n c h ) . Aso, K . , Deneau, D . G . , D r u l i g , L . , Wilkinson, D . I . , and F a r b e r , E.M.: E p i d e r m a l S y n t h e s i s of P r o s t a g l a n d i n s and T h e i r Effect on Levels of Cyclic A d e n o s i n e 3 ' , 5 ' - M o n o p h o s p h a t e . J . I n v e s t . Dermatol. 64: 326-331, 1975. B e n g t s s o n , E . , K r a k a u , C . E . T . , and Ohman, R.: The I n h i b i t i n g Effect of Indomethacin on the Disruption of the Blood-Aqueous B a r r i e r in the Rabbit Eye. Measurement of the Aqueous F l a r e . I n v e s t . Ophthalmol. 14: 306-312, 1975. D r a y , F . , C h a r b o n n e l , B . , Bechetoille, A . , Nou, B . , and S a r a u x , H.: P r o s t a g l a n d i n s E 2 and F2~in Aqueous Humor D u r i n g E a r l y Postcontusion Ocular H y p e r t e n s i o n in the Rabbit. A r c h . Ophthalmol. ( P a r i s ) 34: 899-906, 1974; ( F r e n c h ) . E a g l s t e i n , W . H . , and Weinstein, G .D .: P r o s t a g l a n d i n and DNA S y n t h e s i s in ltuman Skin: P o s s i b l e Relationship to Ultraviolet Light Effects. J . I n v e s t . Dermatol. 64: 386-389, 1975. Jampol, L . M . , Neufeld, A . H . , and S e a r s , M.L.: Pathways for the Response of the Eye to I n j u r y . Invest Ophthalmol. 14: 184-189, 1975.

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Kadlec, O . , and Radomirov, R.: Effects of Prostagiandins F2~ and E 1 on the Longitudinal and Circular Smooth Muscle of the Guinea Pig Caecum in Relation to the Concentration of Extracellular Calcium. Naunyn-Schmiedebergs Arch. Pharmacol. 288: 335-343, 1975. Knoll, J . , Illes, P . , and Torma, Z .: The Effect of PGE 2 on Contraction Delay and Velocity of the Field Stimulated Guinea-Pig Vas Deferens. Neuropharraaoology 14: 317-324, 1975. Korossy, S . , and S z u r g e n t , J . : The Role of Prostaglandins in the Skin. Dermatol. Monatsschr. 161: 177-186, 1975; (Germna). Sauk, J . J . , J r . , White, J . G . , and Witkop, C . J . : Influence of Prostaglandins E 1 . E 2 , and Arachidonate on Melanosomes in Melanocytes and Keratinocyte$ of Anagen Hair Bulbs in Vitro. J. Invest. Dermatol. 64: 332-337, 1975. S n y d e r , D.S .: Cutaneous Effects of Topical Indomethacin, an Inhibitor of Prostaglandin S y n t h e s i s , on UV-Damaged Skin. J. Invest. Dermatol. 64: 322-325, 1975. Zink, H . A . , Podos, S .M., and Becker, B.: Modification by Imidazoles of Ocular Inflammatory and P r e s s u r e Responses. Invest Ophthalmol. 14: 280-285, 1975.

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