Proteins and peptides

Proteins and peptides

Book Reviews Proteins and Peptides---Edited by H. U. Bergmeyer. 571 pp. 1986. VCH Weinheim, Deerfield Beach, FA. DM 310. Methods of Enzymatic Analysis...

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Book Reviews Proteins and Peptides---Edited by H. U. Bergmeyer. 571 pp. 1986. VCH Weinheim, Deerfield Beach, FA. DM 310. Methods of Enzymatic Analysis Vol IX 3rd edition. This multi author volume deals with enzymatic and enzyme immunoassays of specific proteins and peptides. The chapters deals with urinary albumin, retinol binding proteins, lactoferrin, ferritin, thyroglobulin, thyroxine binding globulin, ~:fetoproteins, carcinoembryonic antigen, pregnancy specific fl-glycoprotein, pregnancy associated plasma protein A, collagen, fibronectin, myoglobin, myosin heavy chain, interferon, fl2-microglobulin, compliment C5a antigen, sex associated antigen (H-Y), ~:microglobulin, kinogens, calmodulin, coaggulation protein C; hormones (ACTH, human growth hormone, prolactin, FSH, TSH, HCG, glucagon, insulin, secretin, gastrin, angiotensin I, calcitonin, T3, T4). Each section has a short introduction that provides basic information on the substance to be tested, practical details of how to assay the substances including preparation of the reagents, equipment required, the test, validation of the method, and further references. A very useful volume.

Antigens and Antibodies--Edited by H. U. Bergmeyer. 509 pp. 1986. VCH Weinheim, Deertield Beach, FA. DM 310. Methods in Enzymatic Analysis Volume X. 3rd edition. This volume is the first of two devoted to practical instructions for the determination of antigens and antibodies. Enzyme immuno assays are available for a wide range of systems and this volume gives those of clinical importance. The multi author chapters deals with problems of standardization, antigen secreting cells, antibody secreting cells, MAb antibody screening, immunoglobulins and immune complexes (IgG, IgM, IgA, IgE), antigens and antibodies in allergic and auto immune diseases (RBC autoantibodies, platelet antibodies, anti-DNA, rheumatoid factors, antisperm, giiadins), antigens and antibodies in viral diseases (herpes simplex, bovine herpes virus 1, pseudorabies virus, varicella zoster, E-B virus, cytomegalus virus, rotavirus and adenovirus, rubella, influenza, mumps, measles, respiratory syncytial virus, rabies, enzootic bovine leukosis, feline leukemia, foot and mouth, hepatitis A, hepatitis B, human T lymphocyte virus III). Each section has a general introduction, practical details how to carry out the assay, and references to further reading. A very useful volume.

The Vital Force: a Study of Bioenergetics--Franklin M Harold. 577 pp. 1986. W. H. Freeman, San Francisco. $37.95.

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This textbook is aimed at students and research workers in physiology, biochemistry, microbiology, and cell biology but will also be useful to all those interested in the functioning of living systems. The chapters deals with energy, work and order; the metabolic web; energy coupling by ion currents; energy transduction in bacteria; useful work in bacteria; vestiges of evolution; mitochondria and oxidative phosphorylation; harvesting the light; carriers, channels and pumps; transport mediators and mechanisms; the major organs of movement; filaments, tubules and vesicles--topics in cell motility; signals for communication and control; morphogenesis and biological order. The text is written in a manner that will interest the reader, giving good background information as well as current views, there are also excellent illustrations. The book will provide information and stimulate the imagination of most readers. Gaddum's Pharmacology. 9th Edition--A. S. V. Burgen and J. F. Mitchell. 253 pp. 1985. Oxford University Press, Oxford. The new edition of this popular textbook has more details on the nature and properties of drug receptors, the mechanisms of action of transmitters in the CNS, and though the drugs are mentioned in the text by their chemical names, there is an appendix giving a list of the approved proprietary and alternative names. All the chapters have been revised and brought up to date. Students should find the text easy to read and understand, and it will provide them with most of the information that they need to know in their basic pharmacology course. Histochemistry, Theoretical and Applied. Volume 2. Analytical Technology. 4th Edition--A. G. E. Pearse. 594 pp. 1985. Churchill Livingstone, London. $125. Professor Pearse has made many valuable contributions to the histochemical localization of specific substances in tissue sections. This volume summarizes much of his practical knowledge and experience of the methods used for the localization of proteins, peptides and amino acids; giycosylated proteins; nucleic acids and nucleo-proteins; carbohydrates and mucosubstances; affinity cytochemistry; aldehydes and ketones; pigments and pigment precursors; biogenic amines; and inorganic constituents and foreign substances. The theoretical basis for each of the tests is provided and there are full practical details of the reagents used and the method of carrying out the staining. Each chapter has an extensive bibliography so the reader can follow up literature. A very useful volume for those who wish to understand what they are doing and why, in their histochemical staining.