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Questions linked to Kampf G. Acquired resistance to chlorhexidine – is it time to establish an ‘antiseptic stewardship’ initiative? J Hosp Infect 2016;94:213–227
Journal of Hospital Infection xxx (2016) 1 Available online at www.sciencedirect.com
Journal of Hospital Infection journal homepage: www.elsevierhealth.com/journals/jhin
Continuing Professional Development and the Journal of Hospital Infection
Questions linked to Kampf G. Acquired resistance to chlorhexidine e is it time to establish an ‘antiseptic stewardship’ initiative? J Hosp Infect, DOI: 10.1016/ j.jhin.2016.08.018 Available online xxx
1. The highest epidemiological cut-off value to determine chlorhexidine digluconate (CHG) resistance in Gramnegative bacteria was proposed as 64 mg/L. For which four Gram-negative bacterial genera was e in at least one study with at least 100 clinical isolates e a median or mean minimum inhibitory concentration (MIC) reported above this cut-off value? 2. Which of the following contribute to CHG resistance in healthcare? (More than one answer may be correct.)
(b) (c) (d) (e) (f)
Specific resistance genes such as qacA/B. The type of application. Specific plasmids. The type of user (patient or healthcare worker). The overall magnitude of exposure.
3. On an intensive care unit, CHG may be used for hand hygiene, mouth wash, skin antisepsis, body wash, and central venous catheter insertion site care. Which one of these applications would contribute most of the CHG per patient-day?
(a) Horizontal gene transfer.
Summarizing the instructions from the Royal College of Pathologists: (1) One CPD point is allowed for each question and answer set (up to five questions and answers). (2) Answers must be recorded referenced back to the questions and recorded in the CPD portfolio. (3) It is essential that participants include the completed response form showing both questions and answers in their portfolio as these may be subject to audit by RCPath. For further information about the Royal College of Pathologists’ CPD scheme and credit allocation, please contact: Professional Standards Unit, CPD Section, Royal College of Pathologists, 2 Carlton House Terrace, London, SW1Y 5AF, UK. E-mail: [email protected] or visit http://www.rcpath.org
http://dx.doi.org/10.1016/j.jhin.2016.08.025 0195-6701/ª 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved. Please cite this article in press as: Questions linked to Kampf G. Acquired resistance to chlorhexidine e is it time to establish an ‘antiseptic stewardship’ initiative? J Hosp Infect, DOI: 10.1016/j.jhin.2016.08.018, Journal of Hospital Infection (2016), http://dx.doi.org/10.1016/ j.jhin.2016.08.025
Journal of Hospital Infection journal homepage: www.elsevierhealth.com/journals/jhin
Continuing Professional Development and the Journal of Hospital Infection
Questions linked to Kampf G. Acquired resistance to chlorhexidine e is it time to establish an ‘antiseptic stewardship’ initiative? J Hosp Infect, DOI: 10.1016/ j.jhin.2016.08.018 Available online xxx
1. The highest epidemiological cut-off value to determine chlorhexidine digluconate (CHG) resistance in Gramnegative bacteria was proposed as 64 mg/L. For which four Gram-negative bacterial genera was e in at least one study with at least 100 clinical isolates e a median or mean minimum inhibitory concentration (MIC) reported above this cut-off value? 2. Which of the following contribute to CHG resistance in healthcare? (More than one answer may be correct.)
(b) (c) (d) (e) (f)
Specific resistance genes such as qacA/B. The type of application. Specific plasmids. The type of user (patient or healthcare worker). The overall magnitude of exposure.
3. On an intensive care unit, CHG may be used for hand hygiene, mouth wash, skin antisepsis, body wash, and central venous catheter insertion site care. Which one of these applications would contribute most of the CHG per patient-day?
(a) Horizontal gene transfer.
Summarizing the instructions from the Royal College of Pathologists: (1) One CPD point is allowed for each question and answer set (up to five questions and answers). (2) Answers must be recorded referenced back to the questions and recorded in the CPD portfolio. (3) It is essential that participants include the completed response form showing both questions and answers in their portfolio as these may be subject to audit by RCPath. For further information about the Royal College of Pathologists’ CPD scheme and credit allocation, please contact: Professional Standards Unit, CPD Section, Royal College of Pathologists, 2 Carlton House Terrace, London, SW1Y 5AF, UK. E-mail: [email protected] or visit http://www.rcpath.org
http://dx.doi.org/10.1016/j.jhin.2016.08.025 0195-6701/ª 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved. Please cite this article in press as: Questions linked to Kampf G. Acquired resistance to chlorhexidine e is it time to establish an ‘antiseptic stewardship’ initiative? J Hosp Infect, DOI: 10.1016/j.jhin.2016.08.018, Journal of Hospital Infection (2016), http://dx.doi.org/10.1016/ j.jhin.2016.08.025