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Radiographic Study of the Mental Foramen in Mongolian Population
ORAL AND MAXILLOFACIAL PATHOLOGY e216 Abstracts Case 2: 27-old-year female, consult for acute dental pain. Physical general examination detects capillary angioma in right frontal and maxillary areas of face, intraoral exam reveals gingival angioma in maxillary tuberosity zone. Case 3: 14-year-old male presents blue maculae and tumor located in lower lip vermillion and internal mucosa, in continuity adjacent gingiva and mouth floor. Case 4: 45-year-old female slowly growing mass in submandibular and parapharyngeal zone. Conclusions: A large diversity in morphology, anatomical areas, and clinical expressions.This diversity suggests that the etiology and/or pathogenic mechanisms are differents. Keywords: deep angiomas, clinical diversity, different etiology
ABSTRACT ITEM PP-455 [WITHDRAWN]. ANALYSIS OF CLINICAL AND HISTOLOGICAL DIAGNOSIS AT DEPARTMENT OF MAXILLOFACIAL SURGERY, FIRST CENTRAL HOSPITAL OF MONGOLIA Delgertsetseg Jargaltsogt1, Uranchimeg Dolgorjav2, Bulgan Chadraabal2, Oyundari Batbulgan2, 1 Department of Maxillofacial Surgery, School of Dentistry, HSUM; 2Department of Preventive and Pediatric Dentistry, School of Dentistry, HSUM Objective: To describe a difference between clinical and histological diagnosis of biomaterials, which was taken from patients at Department of Maxillofacial Surgery, First Central Hospital of Mongolia. Study Design: The subjects of our study consisted of 1471 biomaterials, which were taken 2008 to 2012. All histological specimens were prepared by one technician and histological diagnosis was done by the one general pathologist. We did analysis between clinical and pathological diagnosis by SPSS software. Results: There are 21% (309) malignant tumor case and 79% (1162) other lesions (p<0.01). The difference of clinical and histological diagnosis is 44% (133) of malignant tumor and 63% (739) of other lesions (p<0.01). Conclusions: We are considered that all clinical diagnosis doesn’t approve by histological diagnosis. It may be related with not have oral pathologists, not be taken biopsy pre and post operation and not have proper technique and equipments. Keywords: malignant tumor, histological diagnosis, clinical diagnosis
RADIOGRAPHIC STUDY OF THE MENTAL FORAMEN IN MONGOLIAN POPULATION Khentii Lkhamsuren1, Unurzul Altankhuyag2, Delgertsetseg Jargaltsogt2, Ayanga Gongorjav3, Tserendulam Dashnyam3, Bayasgalan Rentsen3, Erdenetsogt Jargaldawaa3, 1Department of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; 2Department of Preventive and Pediatric Dentistry, School of Dentistry, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; 3Department of Oral and Maxillofacial Surgery, National Center for Maternal and Child Health, Ulaanbaatar, Mongolia Objective: To determine the most common position of the mental foramen in a Mongolian population and to compare the results with those reported for other populations.
OOOO March 2015 Study Design: This study identified the position of the mental foramen in a more representative radiographs of the Mongolian population. Two hundred and twenty two (95 males, 127 females) panoramic radiographs of a Mongolian population from dental centers were studied. The patients’ age ranged from 15 to 66 years, with a mean age of 27.4 years. Ethnic, gender differences investigated. Results: In patients (58.8%), the mental foramen was below the second premolar. In 30.2%, it was between the first and second premolar, and in 2.5%, it was below the first premolar. Conclusions: It is important to know the position of the mental foramen for the placement of osseointegrated implants in the mandibular premolar region. The most common position of the mental foramen of Mongolians is below the second premolar. Keywords: mental nerve, mental foramen, panoramic, radiographic measurement, anatomy
EXPRESSION OF NEUROENDOCRINE CELL MARKERS IN AMELOBLASTOMAS Takanaga Ochiai, Keisuke Nakano, Hiromasa Hasegawa, Department of Oral Pathology, School of Dentistry, Matsumoto Dental University Japan Objective: Although some investigators reported CD56 expression in ameloblastomas, neuroendocrine differentiation is still unknown. Therefore, we aimed to determine localization of neuroendocrine cell markers in ameloblastomas. Study Design: Twenty-five archived cases were selected. CD56, synaptophysin and chromogranin A were analyzed an immunohistochemistory, followed by gene expression analysis by RT-RCR on formalin-fixed paraffin embedded samples. Results: Sixteen cases showed that CD56 expressed in columnar cells. Two cases demonstrated synaptophysin in small part of the nest. Chromogranin A was not found in all cases. Interestingly, we found two case that co-expressed CD56 and synaptophysin in some parts of columnar cells. Furthermore, one case expressed mRNA of CD56 and synaptophysin. Conclusions: Some investigators reported CD56 expression in tooth germ development and ameloblastoma. It has also been reported that neural crest-derived cells emigrated to enamel organ. Our result might suggest that CD56-positive cells partially differentiated into synaptophysin-positive cells in ameloblastomas. Keywords: ameloblastoma, neuroendocrine cell, CD56, synaptophysin
LOCAL ADMINISTRATION OF ALLOGENEIC MESENCHYMAL STEM CELLS (MSCs) AT DYSPLASIA STAGE RETARDS THE PROGRESSION OF ORAL SQUAMOUS CELL CARCINOMA (OSCC) Anita Plaza1, Martha Arango2, Flavia Bruna2, Iris Espinoza2, Paulette Conget2, 1 Doctorado en Ciencias Médicas, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile; 2Instituto de Ciencias, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile Objective: Worldwide, OSCC accounted for 120.000 deaths per year. Currently, there are no data related to the impact of donor MSCs on the progression of OSCC. The aim of present work was to determine whether local administration of allogeneic MSCs, at dysplasia stage, modify OSCC progression. Study Design: OSCC was induced in Syrian hamster by topical application of a tobacco-related carcinogen. Vehicle, 1 or 3 million allogeneic MSCs were injected nearby dysplastic lesions. Their evolution (hyperplasia/dysplasia/papilloma/
ABSTRACT ITEM PP-455 [WITHDRAWN]. ANALYSIS OF CLINICAL AND HISTOLOGICAL DIAGNOSIS AT DEPARTMENT OF MAXILLOFACIAL SURGERY, FIRST CENTRAL HOSPITAL OF MONGOLIA Delgertsetseg Jargaltsogt1, Uranchimeg Dolgorjav2, Bulgan Chadraabal2, Oyundari Batbulgan2, 1 Department of Maxillofacial Surgery, School of Dentistry, HSUM; 2Department of Preventive and Pediatric Dentistry, School of Dentistry, HSUM Objective: To describe a difference between clinical and histological diagnosis of biomaterials, which was taken from patients at Department of Maxillofacial Surgery, First Central Hospital of Mongolia. Study Design: The subjects of our study consisted of 1471 biomaterials, which were taken 2008 to 2012. All histological specimens were prepared by one technician and histological diagnosis was done by the one general pathologist. We did analysis between clinical and pathological diagnosis by SPSS software. Results: There are 21% (309) malignant tumor case and 79% (1162) other lesions (p<0.01). The difference of clinical and histological diagnosis is 44% (133) of malignant tumor and 63% (739) of other lesions (p<0.01). Conclusions: We are considered that all clinical diagnosis doesn’t approve by histological diagnosis. It may be related with not have oral pathologists, not be taken biopsy pre and post operation and not have proper technique and equipments. Keywords: malignant tumor, histological diagnosis, clinical diagnosis
RADIOGRAPHIC STUDY OF THE MENTAL FORAMEN IN MONGOLIAN POPULATION Khentii Lkhamsuren1, Unurzul Altankhuyag2, Delgertsetseg Jargaltsogt2, Ayanga Gongorjav3, Tserendulam Dashnyam3, Bayasgalan Rentsen3, Erdenetsogt Jargaldawaa3, 1Department of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; 2Department of Preventive and Pediatric Dentistry, School of Dentistry, Health Sciences University of Mongolia, Ulaanbaatar, Mongolia; 3Department of Oral and Maxillofacial Surgery, National Center for Maternal and Child Health, Ulaanbaatar, Mongolia Objective: To determine the most common position of the mental foramen in a Mongolian population and to compare the results with those reported for other populations.
OOOO March 2015 Study Design: This study identified the position of the mental foramen in a more representative radiographs of the Mongolian population. Two hundred and twenty two (95 males, 127 females) panoramic radiographs of a Mongolian population from dental centers were studied. The patients’ age ranged from 15 to 66 years, with a mean age of 27.4 years. Ethnic, gender differences investigated. Results: In patients (58.8%), the mental foramen was below the second premolar. In 30.2%, it was between the first and second premolar, and in 2.5%, it was below the first premolar. Conclusions: It is important to know the position of the mental foramen for the placement of osseointegrated implants in the mandibular premolar region. The most common position of the mental foramen of Mongolians is below the second premolar. Keywords: mental nerve, mental foramen, panoramic, radiographic measurement, anatomy
EXPRESSION OF NEUROENDOCRINE CELL MARKERS IN AMELOBLASTOMAS Takanaga Ochiai, Keisuke Nakano, Hiromasa Hasegawa, Department of Oral Pathology, School of Dentistry, Matsumoto Dental University Japan Objective: Although some investigators reported CD56 expression in ameloblastomas, neuroendocrine differentiation is still unknown. Therefore, we aimed to determine localization of neuroendocrine cell markers in ameloblastomas. Study Design: Twenty-five archived cases were selected. CD56, synaptophysin and chromogranin A were analyzed an immunohistochemistory, followed by gene expression analysis by RT-RCR on formalin-fixed paraffin embedded samples. Results: Sixteen cases showed that CD56 expressed in columnar cells. Two cases demonstrated synaptophysin in small part of the nest. Chromogranin A was not found in all cases. Interestingly, we found two case that co-expressed CD56 and synaptophysin in some parts of columnar cells. Furthermore, one case expressed mRNA of CD56 and synaptophysin. Conclusions: Some investigators reported CD56 expression in tooth germ development and ameloblastoma. It has also been reported that neural crest-derived cells emigrated to enamel organ. Our result might suggest that CD56-positive cells partially differentiated into synaptophysin-positive cells in ameloblastomas. Keywords: ameloblastoma, neuroendocrine cell, CD56, synaptophysin
LOCAL ADMINISTRATION OF ALLOGENEIC MESENCHYMAL STEM CELLS (MSCs) AT DYSPLASIA STAGE RETARDS THE PROGRESSION OF ORAL SQUAMOUS CELL CARCINOMA (OSCC) Anita Plaza1, Martha Arango2, Flavia Bruna2, Iris Espinoza2, Paulette Conget2, 1 Doctorado en Ciencias Médicas, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile; 2Instituto de Ciencias, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile Objective: Worldwide, OSCC accounted for 120.000 deaths per year. Currently, there are no data related to the impact of donor MSCs on the progression of OSCC. The aim of present work was to determine whether local administration of allogeneic MSCs, at dysplasia stage, modify OSCC progression. Study Design: OSCC was induced in Syrian hamster by topical application of a tobacco-related carcinogen. Vehicle, 1 or 3 million allogeneic MSCs were injected nearby dysplastic lesions. Their evolution (hyperplasia/dysplasia/papilloma/