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Re: First Clinical Evaluation of a New Single-Use Flexible Ureteroscope (LithoVue™): A European Prospective Multicentric Feasibility Study
UROLITHIASIS/ENDOUROLOGY
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findings highlight the importance of inflammatory pathways in the pathophysiology of calcium oxalate nephrocalcinosis induced renal damage. Inflammasome induced cytokine release may also have a role in this process. Dean G. Assimos, MD
Suggested Reading Hughes FM Jr, Hill HM, Wood CM et al: The NLRP3 inflammasome mediates inflammation produced by bladder outlet obstruction. J Urol 2016; 195: 1598. Joshi S, Wang W, Peck AB et al: Activation of the NLRP3 inflammasome in association with calcium oxalate crystal induced reactive oxygen species in kidneys. J Urol 2015; 193: 1684.
Re: Hypercalcemia, Hypercalciuria, and Kidney Stones in Long-Term Studies of Vitamin D Supplementation: A Systematic Review and Meta-Analysis Z. Malihi, Z. Wu, A. W. Stewart, C. M. Lawes and R. Scragg School of Population Health, University of Auckland, Auckland, New Zealand Am J Clin Nutr 2016; 104: 1039e1051. doi: 10.3945/ajcn.116.134981
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27604776 Editorial Comment: This meta-analysis demonstrated that vitamin D supplementation was not associated with a risk of kidney stones. However, there was an increased risk of hypercalciuria and hypercalcemia. Previously reported metabolic studies have not shown that vitamin D supplementation in those with deficient vitamin D levels augments urinary calcium excretion. Dean G. Assimos, MD
Suggested Reading Pitman MS, Cheetham PJ, Hruby GW et al: Vitamin D deficiency in the urological population: a single center analysis. J Urol 2011; 186: 1395.
Re: First Clinical Evaluation of a New Single-Use Flexible Ureteroscope (LithoVueTM): A European Prospective Multicentric Feasibility Study S. Doizi, G. Kamphuis, G. Giusti, K. H. Andreassen, T. Knoll, P. J. Osther, C. Scoffone, rez-Fentes, S. Proietti, O. Wiseman, J. de la Rosette and O. Traxer D. Pe Department of Urology and Groupe de Recherche Clinique sur la Lithiase Urinaire, Tenon Hospital, Assistance Publique-Hoˆpitaux de Paris and Pierre et Marie Curie University, Paris, France, Department of Urology, Academic Medical Center, Amsterdam, The Netherlands, Ville Turro Division, Department of Urology, IRCCS San Raffaele Scientific Institute, Milan and Department of Urology, Cottolengo Hospital, Turin, Italy, Department of Urology, Lillebaelt Hospital, University of Southern Denmark, Fredericia, Denmark, Department of Urology, Klinikum Sindelfingen-Bo¨blingen, Sindelfingen, Germany, Department of Urology, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago De Compostela, Spain, and Department of Urology, Addenbrooke’s Hospital, Cambridge, United Kingdom World J Urol 2016; Epub ahead of print. doi: 10.1007/s00345-016-1936-x
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27671898 Editorial Comment: These investigators assessed the clinical usefulness of a disposable digital flexible ureteroscope. Overall the device performed well, although there was device failure in 5% of cases. This instrument has time limited use. A cost analysis should be done at institutions contemplating using this device to determine whether there is an economic advantage. Perhaps this instrument can be selectively used in cases where a long operative time is anticipated as it may limit damage to “nondisposable scopes” and reduce high cost repairs. Dean G. Assimos, MD
Suggested Reading Carey RI, Gomez CS, Maurici G et al: Frequency of ureteroscope damage seen at a tertiary care center. J Urol 2006; 176: 607. Hollenbeck BK, Spencer SL and Faerber GJ: Use of a working channel catheter during flexible ureteroscopic laser lithotripsy. J Urol 2000; 163: 1808.
Dochead: Urological Survey
LIT 5.4.0 DTD JURO14259_proof 15 December 2016 3:15 am EO:
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findings highlight the importance of inflammatory pathways in the pathophysiology of calcium oxalate nephrocalcinosis induced renal damage. Inflammasome induced cytokine release may also have a role in this process. Dean G. Assimos, MD
Suggested Reading Hughes FM Jr, Hill HM, Wood CM et al: The NLRP3 inflammasome mediates inflammation produced by bladder outlet obstruction. J Urol 2016; 195: 1598. Joshi S, Wang W, Peck AB et al: Activation of the NLRP3 inflammasome in association with calcium oxalate crystal induced reactive oxygen species in kidneys. J Urol 2015; 193: 1684.
Re: Hypercalcemia, Hypercalciuria, and Kidney Stones in Long-Term Studies of Vitamin D Supplementation: A Systematic Review and Meta-Analysis Z. Malihi, Z. Wu, A. W. Stewart, C. M. Lawes and R. Scragg School of Population Health, University of Auckland, Auckland, New Zealand Am J Clin Nutr 2016; 104: 1039e1051. doi: 10.3945/ajcn.116.134981
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27604776 Editorial Comment: This meta-analysis demonstrated that vitamin D supplementation was not associated with a risk of kidney stones. However, there was an increased risk of hypercalciuria and hypercalcemia. Previously reported metabolic studies have not shown that vitamin D supplementation in those with deficient vitamin D levels augments urinary calcium excretion. Dean G. Assimos, MD
Suggested Reading Pitman MS, Cheetham PJ, Hruby GW et al: Vitamin D deficiency in the urological population: a single center analysis. J Urol 2011; 186: 1395.
Re: First Clinical Evaluation of a New Single-Use Flexible Ureteroscope (LithoVueTM): A European Prospective Multicentric Feasibility Study S. Doizi, G. Kamphuis, G. Giusti, K. H. Andreassen, T. Knoll, P. J. Osther, C. Scoffone, rez-Fentes, S. Proietti, O. Wiseman, J. de la Rosette and O. Traxer D. Pe Department of Urology and Groupe de Recherche Clinique sur la Lithiase Urinaire, Tenon Hospital, Assistance Publique-Hoˆpitaux de Paris and Pierre et Marie Curie University, Paris, France, Department of Urology, Academic Medical Center, Amsterdam, The Netherlands, Ville Turro Division, Department of Urology, IRCCS San Raffaele Scientific Institute, Milan and Department of Urology, Cottolengo Hospital, Turin, Italy, Department of Urology, Lillebaelt Hospital, University of Southern Denmark, Fredericia, Denmark, Department of Urology, Klinikum Sindelfingen-Bo¨blingen, Sindelfingen, Germany, Department of Urology, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago De Compostela, Spain, and Department of Urology, Addenbrooke’s Hospital, Cambridge, United Kingdom World J Urol 2016; Epub ahead of print. doi: 10.1007/s00345-016-1936-x
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27671898 Editorial Comment: These investigators assessed the clinical usefulness of a disposable digital flexible ureteroscope. Overall the device performed well, although there was device failure in 5% of cases. This instrument has time limited use. A cost analysis should be done at institutions contemplating using this device to determine whether there is an economic advantage. Perhaps this instrument can be selectively used in cases where a long operative time is anticipated as it may limit damage to “nondisposable scopes” and reduce high cost repairs. Dean G. Assimos, MD
Suggested Reading Carey RI, Gomez CS, Maurici G et al: Frequency of ureteroscope damage seen at a tertiary care center. J Urol 2006; 176: 607. Hollenbeck BK, Spencer SL and Faerber GJ: Use of a working channel catheter during flexible ureteroscopic laser lithotripsy. J Urol 2000; 163: 1808.
Dochead: Urological Survey
LIT 5.4.0 DTD JURO14259_proof 15 December 2016 3:15 am EO:
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