- Email: [email protected]
Recurrence and mortality of bladder cancers across age groups
8th European Multidisciplinary Meeting on Urological Cancers, 24-27 November 2016, Milan, Italy
P107
Recurrence and mortality of bladder cancers across age groups Eur Urol Suppl 2016; 15(13);e1697
Bhuvanagiri A.1, Kannan S.1, Butu D.1, Kelleher J.1, Kowalski P.1, Alexandrou K.1, Ahiaku E.1, Breeze J.2, Hussain M.2 1
Ysbyty Gwynedd, Dept. of Urology, Bangor, United Kingdom, 2Bangor University, Dept. of Statistics, Bangor, United Kingdom INTRODUCTION & OBJECTIVES: We compared histological grading and staging, recurrence and mortality of Transitional Cell Carcinoma (TCC) of the bladder across age groups (5th - 8th decade). MATERIAL & METHODS: Retrospective analysis of patients with TCC between 2003 and 2015 in North Wales Hospital. 593 patients were diagnosed with TCC (448 Male = 76%, Mean Age = 72.1 years; range = 50-89). RESULTS: Histology showed G1 (N = 287, 48%), G2 (N = 183, 24%), and G3 (N = 123, 21%); NonInvasive (CIS/PTA/PT1, N = 451, 76%), and Invasive (PT2, N = 142, 24%). Neither histological grading, staging, nor recurrence rate were significant across age groups respectively (p = 0.63, p = 0.39, p = 0.35).Forty five percent (N = 87) of patients died in the group with recurrences; this was only 38% (N = 152) in those without recurrences. In those who had recurrences, we did not see any change in mortality rate across the different age groups (p = 0.71). However, in patients without recurrences, we saw a marginal increase in the mortality in over 60’s compared to the 50-59 group ([p = 0.06], 50-59 (N = 5, 17%), 60-69 (N = 42, 36%), 70-79 (N = 69, 43%), 80-89 (N = 36, 40%).
Eur Urol Suppl 2016; 15(13);e1697
8th European Multidisciplinary Meeting on Urological Cancers, 24-27 November 2016, Milan, Italy
P107
Recurrence and mortality of bladder cancers across age groups Eur Urol Suppl 2016; 15(13);e1698
CONCLUSIONS: Our study confirms that there is no statistically significant difference in the histological grading, staging and recurrence rate across age groups (50-89). Mortality rates did not differ across the age groups with TCC recurrences, but did differ in those without recurrences.
Eur Urol Suppl 2016; 15(13);e1698 Powered by TCPDF (www.tcpdf.org)
P107
Recurrence and mortality of bladder cancers across age groups Eur Urol Suppl 2016; 15(13);e1697
Bhuvanagiri A.1, Kannan S.1, Butu D.1, Kelleher J.1, Kowalski P.1, Alexandrou K.1, Ahiaku E.1, Breeze J.2, Hussain M.2 1
Ysbyty Gwynedd, Dept. of Urology, Bangor, United Kingdom, 2Bangor University, Dept. of Statistics, Bangor, United Kingdom INTRODUCTION & OBJECTIVES: We compared histological grading and staging, recurrence and mortality of Transitional Cell Carcinoma (TCC) of the bladder across age groups (5th - 8th decade). MATERIAL & METHODS: Retrospective analysis of patients with TCC between 2003 and 2015 in North Wales Hospital. 593 patients were diagnosed with TCC (448 Male = 76%, Mean Age = 72.1 years; range = 50-89). RESULTS: Histology showed G1 (N = 287, 48%), G2 (N = 183, 24%), and G3 (N = 123, 21%); NonInvasive (CIS/PTA/PT1, N = 451, 76%), and Invasive (PT2, N = 142, 24%). Neither histological grading, staging, nor recurrence rate were significant across age groups respectively (p = 0.63, p = 0.39, p = 0.35).Forty five percent (N = 87) of patients died in the group with recurrences; this was only 38% (N = 152) in those without recurrences. In those who had recurrences, we did not see any change in mortality rate across the different age groups (p = 0.71). However, in patients without recurrences, we saw a marginal increase in the mortality in over 60’s compared to the 50-59 group ([p = 0.06], 50-59 (N = 5, 17%), 60-69 (N = 42, 36%), 70-79 (N = 69, 43%), 80-89 (N = 36, 40%).
Eur Urol Suppl 2016; 15(13);e1697
8th European Multidisciplinary Meeting on Urological Cancers, 24-27 November 2016, Milan, Italy
P107
Recurrence and mortality of bladder cancers across age groups Eur Urol Suppl 2016; 15(13);e1698
CONCLUSIONS: Our study confirms that there is no statistically significant difference in the histological grading, staging and recurrence rate across age groups (50-89). Mortality rates did not differ across the age groups with TCC recurrences, but did differ in those without recurrences.
Eur Urol Suppl 2016; 15(13);e1698 Powered by TCPDF (www.tcpdf.org)