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Int. J. Oral Maxillofac. Surg. 2010; 39: 1240–1241 doi:10.1016/j.ijom.2010.04.025, available online at http://www.sciencedirect.com
Abstracts from international literature Spanish Application of botulinum toxin-A for treatment of Frey’s syndrome J. Mareque, J. Gonzalez Lagunas, C. Bassas, G. Raspall Revista Espa˜nola de Cirugía Oral y Maxilofacial 2008: 30: 327–340 The authors presented a study about the use of botulinum toxin-A for the treatment of Frey’s syndrome (auriculo-temporal syndrome). A retrospective review on 289 surgical interventions on the parotid glands confirmed Frey’s syndrome affected 7.2% of cases (31 patients) and was the second most frequent complication behind transitory facial paralysis. Seven cases were excluded from the study due to malignant aetiology, while 10 out of 20 remaining cases agreed to be included in the study. The mean age of this group was 61.8 years, ranging from 40 to 82 years. Six patients had a diagnosis of pleomorphic adenoma, two of Warthin’s tumour, one of lymphangioma and one of haemangioma. Surgical techniques were superficial parotidectomy in eight cases, total conservative parotidectomy in one case and partial parotidectomy in one case. Tests were performed to quantify the skin surface affected. Once the affected area suffering local hyperhydrosis was defined, 0.1 ml (10 units) of botulinum toxin-A (Botox® ) was injected into the dermis in every square centimetre of the affected areas. Follow-up was carried out at 15th days and at 1, 3, 6, 9, 12, 15 and 18 months after the injection. Results of the study did not show any subjective improvement in the quality of life of all patients while local nor systemic side effects were identified (potential risk of pain, oedema, ecchymosis, headache, facial palsy, nausea). Sweating disappeared in all cases. The 0901-5027/1201240+02 $36.00/0
effect started 48 h after injection, reaching the maximum effect between 10 and 14 days after injection. The mean duration of effect was 16 months, ranging from 12 to 22 months. The authors concluded that intradermal injection of botulinum toxin-A was an effective and reproducible method for controlling the symptoms in established auriculo-temporal syndrome without local or systemic side effects. JULIO ACERO doi:10.1016/j.ijom.2010.04.026
Portuguese (Brazil) Cranial vault reconstruction by different materials: comparative histological study in rabbits M.F.R. Gabrielli, M.A.C. Gabrielli, E. Hochuli-Vieira, J.G. Padilha Filho, S. Saska, T. Okamoto, V.A. Pereira Filho, P.D.A. Bolini Rev Bras Cir Traumatol Buco-MaxiloFacial 2009: 6: 43–52 Forty adult male rabbits (Oryctolagus cuniculus) received, under general anaesthesia, bilateral parietal ostectomies with a 6 mm trephine bur to create full thickness critical size defects. The animals were divided into four groups, as follows: Group I: Group II: Group III: Group IV:
Bone defect filled with blood clot Autogenous bone graft harvested from the contralateral side High density porous polyethylene implant (Medpor) Calcium phosphate cement (Norian CRS)
Eight animals were sacrificed in each experimental period of 5, 15, 30, 60 and 120 days after the operation and specimens followed routine laboratory procedures
and haematoxylin and eosin staining for histological evaluation. Results achieved the following conclusions: (1) The bone defects filled with blood clot only were not repaired by bone, (2) resorption and bone substitution of the calvarial bone grafts was not uniform and occurred in varying degrees, but allowed for complete osseous healing of the host beds, (3) the porous high density polyethylene implants were biocompatible and allowed intense connective tissue formation into their pores, (4) significant bone formation was not observed within the polyethylene implants, although isolated calcified spicules were found in some specimens and (5) calcium phosphate cement was biocompatible and osteoconductive, allowing significant new bone formation in the host beds, although remains of material were still present after 120 days. The rate of new bone formation in this case was less predictable than observed for autogenous bone grafts. MARIO GABRIELLI doi:10.1016/j.ijom.2010.04.027
Italian Techniques of endoscopic access to anterior basicranium tumours P. Castelnuovo, P. Battaglia Rivista italiana di Chirurgia MaxilloFacciale 2007: 19: 11–13 Malignant lesions of sinonasal region may be removed by endoscopic access. It became possible to apply this technique to tumours with a greater extent during the last 10 years. The endoscopic nasal approach to the anterior skull base could be a valid alternative for surgical treatment of lesions in these regions. The development of new instruments and techniques made it possible to excise large lesions and
Abstracts from international literature Spanish Application of botulinum toxin-A for treatment of Frey’s syndrome J. Mareque, J. Gonzalez Lagunas, C. Bassas, G. Raspall Revista Espa˜nola de Cirugía Oral y Maxilofacial 2008: 30: 327–340 The authors presented a study about the use of botulinum toxin-A for the treatment of Frey’s syndrome (auriculo-temporal syndrome). A retrospective review on 289 surgical interventions on the parotid glands confirmed Frey’s syndrome affected 7.2% of cases (31 patients) and was the second most frequent complication behind transitory facial paralysis. Seven cases were excluded from the study due to malignant aetiology, while 10 out of 20 remaining cases agreed to be included in the study. The mean age of this group was 61.8 years, ranging from 40 to 82 years. Six patients had a diagnosis of pleomorphic adenoma, two of Warthin’s tumour, one of lymphangioma and one of haemangioma. Surgical techniques were superficial parotidectomy in eight cases, total conservative parotidectomy in one case and partial parotidectomy in one case. Tests were performed to quantify the skin surface affected. Once the affected area suffering local hyperhydrosis was defined, 0.1 ml (10 units) of botulinum toxin-A (Botox® ) was injected into the dermis in every square centimetre of the affected areas. Follow-up was carried out at 15th days and at 1, 3, 6, 9, 12, 15 and 18 months after the injection. Results of the study did not show any subjective improvement in the quality of life of all patients while local nor systemic side effects were identified (potential risk of pain, oedema, ecchymosis, headache, facial palsy, nausea). Sweating disappeared in all cases. The 0901-5027/1201240+02 $36.00/0
effect started 48 h after injection, reaching the maximum effect between 10 and 14 days after injection. The mean duration of effect was 16 months, ranging from 12 to 22 months. The authors concluded that intradermal injection of botulinum toxin-A was an effective and reproducible method for controlling the symptoms in established auriculo-temporal syndrome without local or systemic side effects. JULIO ACERO doi:10.1016/j.ijom.2010.04.026
Portuguese (Brazil) Cranial vault reconstruction by different materials: comparative histological study in rabbits M.F.R. Gabrielli, M.A.C. Gabrielli, E. Hochuli-Vieira, J.G. Padilha Filho, S. Saska, T. Okamoto, V.A. Pereira Filho, P.D.A. Bolini Rev Bras Cir Traumatol Buco-MaxiloFacial 2009: 6: 43–52 Forty adult male rabbits (Oryctolagus cuniculus) received, under general anaesthesia, bilateral parietal ostectomies with a 6 mm trephine bur to create full thickness critical size defects. The animals were divided into four groups, as follows: Group I: Group II: Group III: Group IV:
Bone defect filled with blood clot Autogenous bone graft harvested from the contralateral side High density porous polyethylene implant (Medpor) Calcium phosphate cement (Norian CRS)
Eight animals were sacrificed in each experimental period of 5, 15, 30, 60 and 120 days after the operation and specimens followed routine laboratory procedures
and haematoxylin and eosin staining for histological evaluation. Results achieved the following conclusions: (1) The bone defects filled with blood clot only were not repaired by bone, (2) resorption and bone substitution of the calvarial bone grafts was not uniform and occurred in varying degrees, but allowed for complete osseous healing of the host beds, (3) the porous high density polyethylene implants were biocompatible and allowed intense connective tissue formation into their pores, (4) significant bone formation was not observed within the polyethylene implants, although isolated calcified spicules were found in some specimens and (5) calcium phosphate cement was biocompatible and osteoconductive, allowing significant new bone formation in the host beds, although remains of material were still present after 120 days. The rate of new bone formation in this case was less predictable than observed for autogenous bone grafts. MARIO GABRIELLI doi:10.1016/j.ijom.2010.04.027
Italian Techniques of endoscopic access to anterior basicranium tumours P. Castelnuovo, P. Battaglia Rivista italiana di Chirurgia MaxilloFacciale 2007: 19: 11–13 Malignant lesions of sinonasal region may be removed by endoscopic access. It became possible to apply this technique to tumours with a greater extent during the last 10 years. The endoscopic nasal approach to the anterior skull base could be a valid alternative for surgical treatment of lesions in these regions. The development of new instruments and techniques made it possible to excise large lesions and