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Studies on the innervation and reinnervation of the urinary bladder in the cat
74 Studies on the Innervation and Reinnervation Bladder in the Cat Takeshi Kadota
of the Urinary
First Department of Surgeo', Ehime Unirersity School of Medicine, l(hime 7c)1-02, Japan The innervation and reinnervation of the urinary bladder was investigated in the cat by means of the retrograde transport of horseradish peroxidase. Peroxidase-labeled cells in dorsal root ganglia were located mainly in the lumbar and sacral segments. Approximately 20% of labeled cells were found in the lumbar dorsal root ganglia and 80% in the sacral dorsal root ganglia. The paravertrebral ganglia, which innervate the bladder, supplied two axonal populations; one population was from the ganglia rostral to L6 (upper group) and the other was from the ganglia caudal to L6 (lower group). The ratio of upper-to-lower group was 1:3. After transection of the hypogastric nerves, horseradish peroxidaselabeled cells decreased markedly in the upper group, indicating that many post-ganglionic fibers of the upper group innervate the bladder via the hypogastric nerves. After transection of the pelvic nerves, there was a marked decrease of labeled cells in the lower group, indicating that many of the post-ganglionic fibers of the lower group innervate the urinary bladder via the pelvic nerve. The average n u m b e r of labeled cells innervating the bladder in dorsal root ganglia, paravertebral ganglia and prevertebral ganglia was calculated as 3,000, 7,000 and 2,(X)0, respectively. The n u m b e r of labeled cells in the paravertebral ganglia was 3 times higher than in prevertebral ganglia. An anastomosis of a transccted pelvic nerve favors the reinnervation of the denervaied bladder. After injection of horseradish peroxidase into the sacral dorsal root ganglia, many labeled fibers anterogradely filled with tracer were found in the pelvic plexus and in all parts t~f the bladder wall. (The Autonomic Nervous System, 28: 313-325, 1991)
of the Urinary
First Department of Surgeo', Ehime Unirersity School of Medicine, l(hime 7c)1-02, Japan The innervation and reinnervation of the urinary bladder was investigated in the cat by means of the retrograde transport of horseradish peroxidase. Peroxidase-labeled cells in dorsal root ganglia were located mainly in the lumbar and sacral segments. Approximately 20% of labeled cells were found in the lumbar dorsal root ganglia and 80% in the sacral dorsal root ganglia. The paravertrebral ganglia, which innervate the bladder, supplied two axonal populations; one population was from the ganglia rostral to L6 (upper group) and the other was from the ganglia caudal to L6 (lower group). The ratio of upper-to-lower group was 1:3. After transection of the hypogastric nerves, horseradish peroxidaselabeled cells decreased markedly in the upper group, indicating that many post-ganglionic fibers of the upper group innervate the bladder via the hypogastric nerves. After transection of the pelvic nerves, there was a marked decrease of labeled cells in the lower group, indicating that many of the post-ganglionic fibers of the lower group innervate the urinary bladder via the pelvic nerve. The average n u m b e r of labeled cells innervating the bladder in dorsal root ganglia, paravertebral ganglia and prevertebral ganglia was calculated as 3,000, 7,000 and 2,(X)0, respectively. The n u m b e r of labeled cells in the paravertebral ganglia was 3 times higher than in prevertebral ganglia. An anastomosis of a transccted pelvic nerve favors the reinnervation of the denervaied bladder. After injection of horseradish peroxidase into the sacral dorsal root ganglia, many labeled fibers anterogradely filled with tracer were found in the pelvic plexus and in all parts t~f the bladder wall. (The Autonomic Nervous System, 28: 313-325, 1991)