Subject Index* A Acetaldehyde The role of acetaldehyde in upper digestive tract cancer in alcoholics (Seitz and Meier). 2007;149:293-7 Adiponectin Adiponectin levels are associated with coronary artery disease across Caucasian and African-American ethnicity (Lu et al). 2007;149:317-23 Advanced glycation end products; see Glycosylation end-products, advanced African continental population groups Ethnic differences in plasma levels of interleukin-8 (IL-8) and granulocyte colony stimulating factor (G-CSF) (Mayr et al). 2007;149:10-4 Air pollutants Effect of ambient particulate matter exposure on hemostasis (Cozzi et al). 2007;149:324-32 Alcoholism The role of acetaldehyde in upper digestive tract cancer in alcoholics (Seitz and Meier). 2007;149:293-7 Amyloid precursor protein secretases; see Endopeptidases Angiogenesis inhibitors Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53 Angiopoietin-1 Expression of angiopoietin-1 in osteoblasts and its inhibition by tumor necrosis factor-alpha and interferon-gamma (Kasama et al). 2007;149:265-73 Angiotensin II Urokinase-type plasminogen activator deficiency (uPA-KO) prevented carotid artery ligation-induced vascular remodeling in mice (Martin-McNulty et al). 2007;149:70-5 Anoxia Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans (Rodway et al). 2007;149:76-84 Anticholesteremic agents Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats (Jeon et al). 2007;149:15-21 Antigens Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Lapierre et al). 2007; 149:107-13 (Review) Anti-inflammatory agents Antitumor and antiinflammatory effects of tetrathiotungstate in comparison with tetrathiomolybdate (Hou et al). 2007;149: 260-4 Antineoplastic agents Antitumor and antiinflammatory effects of tetrathiotungstate in comparison with tetrathiomolybdate (Hou et al). 2007;149: 260-4 *January, pp. 1-54; February, pp. 55-102; March, pp. 103-164; April, pp. 165-236; May, pp. 237-292; June, pp. 293-342.
Antioxidants Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats (Jeon et al). 2007;149:15-21 Apolipoprotein E Immunologic response enhances atherosclerosis—type 1 helper T cell (Th1)-to-type 2 helper T cell (Th2) shift and calcified atherosclerosis in Bacillus Calmette-Guerin (BCG)-treated apolipoprotein E-knockout (apo E⫺/⫺) mice (Shibata et al). 2007;149:62-9 Apoptosis Apoptosis in ibuprofen-induced Stevens-Johnson syndrome (Neuman and Nicar). 2007;149:254-9 Cytokine— chemokine and apoptotic signatures in patients with hepatitis C (Neuman et al). 2007;149:126-36 Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Lapierre et al). 2007; 149:107-13 (Review) Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion (Ruixing et al). 2007;149:152-60 Atherosclerosis Immunologic response enhances atherosclerosis—type 1 helper T cell (Th1)-to-type 2 helper T cell (Th2) shift and calcified atherosclerosis in Bacillus Calmette-Guerin (BCG)-treated apolipoprotein E-knockout (apo E⫺/⫺) mice (Shibata et al). 2007;149:62-9 ATP-binding cassette transporters Genotypic variation in ATP-binding cassette transporter-1 (ABCA1) as contributors to the high and low high-density lipoprotein-cholesterol (HDL-C) phenotype (Mantaring et al). 2007;149:205-10 Attitude of health personnel Are provider self-efficacy and attitudes related to cardiovascular prevention associated with better treatment outcomes? (Litaker et al). 2007;149:165-72 Autoimmune hepatitis; see Hepatitis, autoimmune B Bacillus Calmette-Guerin vaccine; see BCG vaccine Basic helix-loop-helix transcription factors Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 B-cell non-Hodgkin lymphoma; see Lymphoma, B-cell BCG vaccine Immunologic response enhances atherosclerosis—type 1 helper T cell (Th1)-to-type 2 helper T cell (Th2) shift and calcified atherosclerosis in Bacillus Calmette-Guerin (BCG)-treated apolipoprotein E-knockout (apo E⫺/⫺) mice (Shibata et al). 2007;149:62-9 Bilirubin Solvent partition of 14C-unconjugated bilirubin to remove labeled polar contaminants (Ostrow and Mukerjee). 2007;149:37-45 Biological markers Cytokine— chemokine and apoptotic signatures in patients with hepatitis C (Neuman et al). 2007;149:126-36
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Blood coagulation New method to prepare autologous fibrin glue on demand (Alston et al). 2007;149:187-95 Blood pressure Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans (Rodway et al). 2007;149:76-84 Breath tests Measurement of extra-pancreatic secretory function by dipeptide breath test (Ishii et al). 2007;149:298-303
13
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C Cadherins Cleavage of E-cadherin: a mechanism for disruption of the intestinal epithelial barrier by Candida albicans (Frank and Hostetter). 2007;149:211-22 Candida albicans Cleavage of E-cadherin: a mechanism for disruption of the intestinal epithelial barrier by Candida albicans (Frank and Hostetter). 2007;149:211-22 Capillaries Impaired integration of endothelial progenitor cells in capillaries of diabetic wounds is reversible with vascular endothelial growth factor infusion (Singh et al). 2007;149:282-91 Carbazoles Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30
cell cultures from umbilical cord vessels (De Llano et al). 2007;149:1-9 Chelating agents Antitumor and antiinflammatory effects of tetrathiotungstate in comparison with tetrathiomolybdate (Hou et al). 2007;149: 260-4 Chemokines Cytokine— chemokine and apoptotic signatures in patients with hepatitis C (Neuman et al). 2007;149:126-36 Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Lapierre et al). 2007; 149:107-13 (Review) Cholesterol Cholesterol synthesis prevails over absorption in metabolic syndrome (Gylling et al). 2007;149:310-16 Cholesterol, dietary Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats (Jeon et al). 2007;149:15-21 Cholesterol, HDL Effect of plant sterols and exercise training on cholesterol absorption and synthesis in previously sedentary hypercholesterolemic subjects (Varady et al). 2007;149:22-30 Cholesterol, LDL Effect of plant sterols and exercise training on cholesterol absorption and synthesis in previously sedentary hypercholesterolemic subjects (Varady et al). 2007;149:22-30 Chronic lymphocytic leukemia; see Leukemia, lymphocytic, chronic
Carbon radioisotopes Solvent partition of 14C-unconjugated bilirubin to remove labeled polar contaminants (Ostrow and Mukerjee). 2007;149:37-45
Codon Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer (Chien et al). 2007;149:96102
Carcinoma, renal cell SU-011248, a vascular endothelial growth factor receptor-tyrosine kinase inhibitor, controls chronic psoriasis (Keshtgarpour and Dudek). 2007;149:103-6
Codon, nonsense Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP) (Phillips et al). 2007;149:85-91
Cardiomyocytes; see Myocytes, cardiac
Colorectal neoplasms Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer (Chien et al). 2007;149:96102
Cardiovascular diseases Are provider self-efficacy and attitudes related to cardiovascular prevention associated with better treatment outcomes? (Litaker et al). 2007;149:165-72 Carotid artery diseases Urokinase-type plasminogen activator deficiency (uPA-KO) prevented carotid artery ligation-induced vascular remodeling in mice (Martin-McNulty et al). 2007;149:70-5 Carvedilol; see Carbazoles; Propanolamines Cell adhesion molecules Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Lapierre et al). 2007; 149:107-13 (Review)
Coronary arteriosclerosis Adiponectin levels are associated with coronary artery disease across Caucasian and African-American ethnicity (Lu et al). 2007;149:317-23 Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms (Nanni et al). 2007;149:137-44 Corrections Differential gene expression identifies subgroups of renal cell carcinoma (Skubitz et al) (2006;147:250-67). 2007;149:163 Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans (Rodway et al.) (2007;149:76-84). 2007;149:236
Cell culture techniques Procedure to consistently obtain endothelial and smooth muscle cell cultures from umbilical cord vessels (De Llano et al). 2007;149:1-9
Cyclin D; see Cyclins
Cell proliferation Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53
Cyclin-dependent kinase 2 Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53
Cell separation Procedure to consistently obtain endothelial and smooth muscle
Cyclin-dependent kinase 4 Cell-cycle inhibition by TNP-470 in an in vivo model of hepato-
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Subject Index
carcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53 Cyclin-dependent kinase inhibitor p21 Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53 Cyclin E; see Cyclins Cyclins Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53 Cytokines Apoptosis in ibuprofen-induced Stevens-Johnson syndrome (Neuman and Nicar). 2007;149:254-9 Cytokine— chemokine and apoptotic signatures in patients with hepatitis C (Neuman et al). 2007;149:126-36 Immune dysfunction in inflammatory bowel disease (Neuman). 2007;149:173-86 (Review) Immunopathogenesis of hypersensitivity syndrome reactions to sulfonamides (Neuman et al). 2007;149:243-53 D Desmoglein 2 Cleavage of E-cadherin: a mechanism for disruption of the intestinal epithelial barrier by Candida albicans (Frank and Hostetter). 2007;149:211-22 Diabetes mellitus Hemoglobin A1c (HbA1c) predicts future drug treatment for diabetes mellitus: a follow-up study using routine clinical data in a Japanese University hospital (Shimazaki et al). 2007;149: 196-204 Impaired integration of endothelial progenitor cells in capillaries of diabetic wounds is reversible with vascular endothelial growth factor infusion (Singh et al). 2007;149:282-91 Dietary supplements Nutrigenetics and nutraceuticals: the next wave riding on personalized medicine (Subbiah). 2007;149:55-61 (Review) Dipeptides Measurement of extra-pancreatic secretory function by dipeptide breath test (Ishii et al). 2007;149:298-303
13
C-
Disease progression Noninvasive assessment of fibrosis in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) (Miele et al). 2007;149:114-25 (Review) Doxorubicin Antitumor and antiinflammatory effects of tetrathiotungstate in comparison with tetrathiomolybdate (Hou et al). 2007;149: 260-4 Drug contamination Solvent partition of 14C-unconjugated bilirubin to remove labeled polar contaminants (Ostrow and Mukerjee). 2007;149:37-45 Drug hypersensitivity Apoptosis in ibuprofen-induced Stevens-Johnson syndrome (Neuman and Nicar). 2007;149:254-9 Immunopathogenesis of hypersensitivity syndrome reactions to sulfonamides (Neuman et al). 2007;149:243-53 Drug tolerance Immunopathogenesis of hypersensitivity syndrome reactions to sulfonamides (Neuman et al). 2007;149:243-53 Drug toxicity Toxicity and hemodynamic effects after single dose administra-
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tion of MalPEG-hemoglobin (MP4) in rhesus monkeys (Young et al). 2007;149:333-342 Dupuytren’s contracture SU-011248, a vascular endothelial growth factor receptor-tyrosine kinase inhibitor, controls chronic psoriasis (Keshtgarpour and Dudek). 2007;149:103-6 Dust Effect of ambient particulate matter exposure on hemostasis (Cozzi et al). 2007;149:324-32 E Early growth factor-1; see Early growth response protein 1 Early growth response protein 1 Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30 E-cadherin; see Cadherins Electric countershock Irregularity test for very short electrocardiogram (ECG) signals as a method for predicting a successful defibrillation in patients with ventricular fibrillation (Jagricˇ et al). 2007;149:145-51 Electrocardiography Irregularity test for very short electrocardiogram (ECG) signals as a method for predicting a successful defibrillation in patients with ventricular fibrillation (Jagricˇ et al). 2007;149:145-51 Endopeptidases Cleavage of E-cadherin: a mechanism for disruption of the intestinal epithelial barrier by Candida albicans (Frank and Hostetter). 2007;149:211-22 Endothelial cells Procedure to consistently obtain endothelial and smooth muscle cell cultures from umbilical cord vessels (De Llano et al). 2007;149:1-9 Environmental exposure Effect of ambient particulate matter exposure on hemostasis (Cozzi et al). 2007;149:324-32 Epidermal necrolysis, toxic Apoptosis in ibuprofen-induced Stevens-Johnson syndrome (Neuman and Nicar). 2007;149:254-9 Epithelial cells Cleavage of E-cadherin: a mechanism for disruption of the intestinal epithelial barrier by Candida albicans (Frank and Hostetter). 2007;149:211-22 Exercise Effect of plant sterols and exercise training on cholesterol absorption and synthesis in previously sedentary hypercholesterolemic subjects (Varady et al). 2007;149:22-30 F Fatty liver Noninvasive assessment of fibrosis in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) (Miele et al). 2007;149:114-25 (Review) Feces Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer (Chien et al). 2007;149:96102 Ferric compounds Peritoneal effects of intravenous iron sucrose administration in rats (Breborowicz et al). 2007;149:304-9
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Subject Index
Fibrin glue; see Fibrin tissue adhesive Fibrinogen New method to prepare autologous fibrin glue on demand (Alston et al). 2007;149:187-95 Fibrin tissue adhesive New method to prepare autologous fibrin glue on demand (Alston et al). 2007;149:187-95 Fibroblasts Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 Fibrosis Cytokine— chemokine and apoptotic signatures in patients with hepatitis C (Neuman et al). 2007;149:126-36 Noninvasive assessment of fibrosis in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) (Miele et al). 2007;149:114-25 (Review) Flavanones Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats (Jeon et al). 2007;149:15-21 Free light chains; see Immunoglobulin light chains G Genes, ras Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer (Chien et al). 2007;149:96102 Genetic polymorphism; see Polymorphism, genetic Glucose Cholesterol synthesis prevails over absorption in metabolic syndrome (Gylling et al). 2007;149:310-16 Glycosylation end-products, advanced Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 Granulocyte colony-stimulating factor Ethnic differences in plasma levels of interleukin-8 (IL-8) and granulocyte colony stimulating factor (G-CSF) (Mayr et al). 2007;149:10-4 H Head and neck neoplasms The role of acetaldehyde in upper digestive tract cancer in alcoholics (Seitz and Meier). 2007;149:293-7 Health personnel Are provider self-efficacy and attitudes related to cardiovascular prevention associated with better treatment outcomes? (Litaker et al). 2007;149:165-72 Heart failure, congestive Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30 Heart rate Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans (Rodway et al). 2007;149:76-84 Irregularity test for very short electrocardiogram (ECG) signals as
a method for predicting a successful defibrillation in patients with ventricular fibrillation (Jagricˇ et al). 2007;149:145-51 Hemochromatosis Hemochromatosis (HFE) gene splice site mutation IVS5⫹1 G/A in North American Vietnamese with and without phenotypic evidence of iron overload (Steiner et al). 2007;149:92-5 Hemodynamics Toxicity and hemodynamic effects after single dose administration of MalPEG-hemoglobin (MP4) in rhesus monkeys (Young et al). 2007;149:333-342 Hemoglobin A, glycosylated Hemoglobin A1c (HbA1c) predicts future drug treatment for diabetes mellitus: a follow-up study using routine clinical data in a Japanese University hospital (Shimazaki et al). 2007;149: 196-204 Hemoglobin A1c; see Hemoglobin A, glycosylated; Protein precursors Hemoglobins Toxicity and hemodynamic effects after single dose administration of MalPEG-hemoglobin (MP4) in rhesus monkeys (Young et al). 2007;149:333-342 Hemostasis Effect of ambient particulate matter exposure on hemostasis (Cozzi et al). 2007;149:324-32 Hepatitis, autoimmune Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Lapierre et al). 2007; 149:107-13 (Review) Hepatitis C Cytokine— chemokine and apoptotic signatures in patients with hepatitis C (Neuman et al). 2007;149:126-36 Hepatocyte growth factor Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53 Hepatocytes Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Lapierre et al). 2007; 149:107-13 (Review) Hepatoerythropoietic porphyria; see Porphyria, hepatoerythropoietic High-density lipoprotein-cholesterol; see Lipoproteins, HDL cholesterol Homeodomain proteins Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Homeostasis Peritoneal effects of intravenous iron sucrose administration in rats (Breborowicz et al). 2007;149:304-9 HSP70 heat-shock proteins Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 Human genome project Nutrigenetics and nutraceuticals: the next wave riding on personalized medicine (Subbiah). 2007;149:55-61 (Review)
-Hydroxybenzoic acid; see Parabens -Hydroxyphenylpropionic acid; see Phenylpropionates
Translational Research Volume 149, Number 6
Subject Index
Hypercholesterolemia Effect of plant sterols and exercise training on cholesterol absorption and synthesis in previously sedentary hypercholesterolemic subjects (Varady et al). 2007;149:22-30 Hypoglycemic agents Hemoglobin A1c (HbA1c) predicts future drug treatment for diabetes mellitus: a follow-up study using routine clinical data in a Japanese University hospital (Shimazaki et al). 2007;149: 196-204 Hypoxia; see Anoxia I Ibuprofen Apoptosis in ibuprofen-induced Stevens-Johnson syndrome (Neuman and Nicar). 2007;149:254-9 Immune system Immune dysfunction in inflammatory bowel disease (Neuman). 2007;149:173-86 (Review) Immune tolerance Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Lapierre et al). 2007; 149:107-13 (Review) Immunity, mucosal Immune dysfunction in inflammatory bowel disease (Neuman). 2007;149:173-86 (Review) Immunoglobulin light chains Serum-free light chain—a new biomarker for patients with B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia (Martin et al). 2007;149:231-5 Immunoglobulin M Serum-free light chain—a new biomarker for patients with B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia (Martin et al). 2007;149:231-5 Indoles SU-011248, a vascular endothelial growth factor receptor-tyrosine kinase inhibitor, controls chronic psoriasis (Keshtgarpour and Dudek). 2007;149:103-6 Inflammation Cytokine— chemokine and apoptotic signatures in patients with hepatitis C (Neuman et al). 2007;149:126-36 Immune dysfunction in inflammatory bowel disease (Neuman). 2007;149:173-86 (Review) Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms (Nanni et al). 2007;149:137-44 Noninvasive assessment of fibrosis in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) (Miele et al). 2007;149:114-25 (Review) Inflammatory bowel diseases Immune dysfunction in inflammatory bowel disease (Neuman). 2007;149:173-86 (Review) Infusions, intravenous Peritoneal effects of intravenous iron sucrose administration in rats (Breborowicz et al). 2007;149:304-9 Interferon-gamma; see Interferon type II Interferon type II Expression of angiopoietin-1 in osteoblasts and its inhibition by tumor necrosis factor-alpha and interferon-gamma (Kasama et al). 2007;149:265-73 Interleukin-8 Ethnic differences in plasma levels of interleukin-8 (IL-8) and
351
granulocyte colony stimulating factor (G-CSF) (Mayr et al). 2007;149:10-4 Intestinal absorption Effect of plant sterols and exercise training on cholesterol absorption and synthesis in previously sedentary hypercholesterolemic subjects (Varady et al). 2007;149:22-30 Intestinal mucosa Cleavage of E-cadherin: a mechanism for disruption of the intestinal epithelial barrier by Candida albicans (Frank and Hostetter). 2007;149:211-22 Immune dysfunction in inflammatory bowel disease (Neuman). 2007;149:173-86 (Review) Iron overload Hemochromatosis (HFE) gene splice site mutation IVS5⫹1 G/A in North American Vietnamese with and without phenotypic evidence of iron overload (Steiner et al). 2007;149:92-5 Iron sucrose; see Ferric compounds Ischemia Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion (Ruixing et al). 2007;149:152-60 J Janus kinase 2; see Protein-tyrosine kinase; Proto-oncogene proteins K Keratinocytes Apoptosis in ibuprofen-induced Stevens-Johnson syndrome (Neuman and Nicar). 2007;149:254-9 Kidney Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 Kidney diseases Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Kreisler; see MAFB transcription factor L Leukemia, lymphocytic, chronic Serum-free light chain—a new biomarker for patients with B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia (Martin et al). 2007;149:231-5 Ligation Urokinase-type plasminogen activator deficiency (uPA-KO) prevented carotid artery ligation-induced vascular remodeling in mice (Martin-McNulty et al). 2007;149:70-5 LIM homeobox transcription factor 1, beta; see Homeodomain proteins; Transcription factors Lipopolysaccharides Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30 Lipoproteins, HDL cholesterol Genotypic variation in ATP-binding cassette transporter-1 (ABCA1) as contributors to the high and low high-density lipoprotein-cholesterol (HDL-C) phenotype (Mantaring et al). 2007;149:205-10 Liver cirrhosis Cytokine— chemokine and apoptotic signatures in patients with hepatitis C (Neuman et al). 2007;149:126-36
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Subject Index
Noninvasive assessment of fibrosis in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) (Miele et al). 2007;149:114-25 (Review) Liver neoplasms, experimental Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53 Lymphocytes Apoptosis in ibuprofen-induced Stevens-Johnson syndrome (Neuman and Nicar). 2007;149:254-9 Immunopathogenesis of hypersensitivity syndrome reactions to sulfonamides (Neuman et al). 2007;149:243-53 Lymphoma, B-cell Serum-free light chain—a new biomarker for patients with B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia (Martin et al). 2007;149:231-5 M MAFB transcription factor Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Maleimide-polyethylene glycol-modified hemoglobin (MP4); see Hemoglobins; Maleimides Maleimides Toxicity and hemodynamic effects after single dose administration of MalPEG-hemoglobin (MP4) in rhesus monkeys (Young et al). 2007;149:333-342 Matrix metalloproteinases Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms (Nanni et al). 2007;149:137-44 Membrane proteins Cleavage of E-cadherin: a mechanism for disruption of the intestinal epithelial barrier by Candida albicans (Frank and Hostetter). 2007;149:211-22 Metabolic syndrome Cholesterol synthesis prevails over absorption in metabolic syndrome (Gylling et al). 2007;149:310-16 Mitosis Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 Molybdenum Antitumor and antiinflammatory effects of tetrathiotungstate in comparison with tetrathiomolybdate (Hou et al). 2007;149: 260-4 Monocytes Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30 Mutation, missense Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP) (Phillips et al). 2007;149:85-91 Myocytes, cardiac Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion (Ruixing et al). 2007;149:152-60 Myocytes, smooth muscle Procedure to consistently obtain endothelial and smooth muscle
cell cultures from umbilical cord vessels (De Llano et al). 2007;149:1-9 N Naringenin; see Flavanones Neoplasm recurrence, local SU-011248, a vascular endothelial growth factor receptor-tyrosine kinase inhibitor, controls chronic psoriasis (Keshtgarpour and Dudek). 2007;149:103-6 Neoplasms Antitumor and antiinflammatory effects of tetrathiotungstate in comparison with tetrathiomolybdate (Hou et al). 2007;149: 260-4 NF-kappa B Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Nitric-oxide synthase Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans (Rodway et al). 2007;149:76-84 Nuclear factor-B; see NF-kappa B Nutrition physiology Nutrigenetics and nutraceuticals: the next wave riding on personalized medicine (Subbiah). 2007;149:55-61 (Review) Nutrition therapy Nutrigenetics and nutraceuticals: the next wave riding on personalized medicine (Subbiah). 2007;149:55-61 (Review) O Occludin; see Membrane proteins Osteoblasts Expression of angiopoietin-1 in osteoblasts and its inhibition by tumor necrosis factor-alpha and interferon-gamma (Kasama et al). 2007;149:265-73 Oxidative stress Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 P Pancreatic function tests Measurement of extra-pancreatic secretory function by 13Cdipeptide breath test (Ishii et al). 2007;149:298-303 Pancreatitis, chronic Measurement of extra-pancreatic secretory function by 13Cdipeptide breath test (Ishii et al). 2007;149:298-303 Parabens Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats (Jeon et al). 2007;149:15-21 PAX2 transcription factor Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Peritoneal dialysis, continuous ambulatory Peritoneal effects of intravenous iron sucrose administration in rats (Breborowicz et al). 2007;149:304-9 Pharmacogenetics Nutrigenetics and nutraceuticals: the next wave riding on personalized medicine (Subbiah). 2007;149:55-61 (Review)
Translational Research Volume 149, Number 6
Phenylpropionates Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats (Jeon et al). 2007;149:15-21 Phytosterols Effect of plant sterols and exercise training on cholesterol absorption and synthesis in previously sedentary hypercholesterolemic subjects (Varady et al). 2007;149:22-30 Plant sterols; see Phtyosterols Plasma Ethnic differences in plasma levels of interleukin-8 (IL-8) and granulocyte colony stimulating factor (G-CSF) (Mayr et al). 2007;149:10-4 Pod1; see Basic helix-loop-helix transcription factors Podocytes Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Polymorphism, genetic Genotypic variation in ATP-binding cassette transporter-1 (ABCA1) as contributors to the high and low high-density lipoprotein-cholesterol (HDL-C) phenotype (Mantaring et al). 2007;149:205-10 Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms (Nanni et al). 2007;149:137-44 Prevalence of RHD 1227A and hybrid Rhesus box in the general Chinese population (Yang et al). 2007;149:31-6 Polymorphism, single nucleotide Nutrigenetics and nutraceuticals: the next wave riding on personalized medicine (Subbiah). 2007;149:55-61 (Review) Population groups Adiponectin levels are associated with coronary artery disease across Caucasian and African-American ethnicity (Lu et al). 2007;149:317-23 Porphyria, hepatoerythropoietic Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP) (Phillips et al). 2007;149:85-91 Prediabetic state Hemoglobin A1c (HbA1c) predicts future drug treatment for diabetes mellitus: a follow-up study using routine clinical data in a Japanese University hospital (Shimazaki et al). 2007;149: 196-204 Primary care providers; see Health personnel Propanolamines Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30 Protamines New method to prepare autologous fibrin glue on demand (Alston et al). 2007;149:187-95 Protein precursors Hemoglobin A1c (HbA1c) predicts future drug treatment for diabetes mellitus: a follow-up study using routine clinical data in a Japanese University hospital (Shimazaki et al). 2007;149: 196-204 Protein-tyrosine kinase Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in
Subject Index
353
normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 Proto-oncogene proteins Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 Psoriasis SU-011248, a vascular endothelial growth factor receptor-tyrosine kinase inhibitor, controls chronic psoriasis (Keshtgarpour and Dudek). 2007;149:103-6 Pyrroles SU-011248, a vascular endothelial growth factor receptor-tyrosine kinase inhibitor, controls chronic psoriasis (Keshtgarpour and Dudek). 2007;149:103-6 R Recombinant proteins Impaired integration of endothelial progenitor cells in capillaries of diabetic wounds is reversible with vascular endothelial growth factor infusion (Singh et al). 2007;149:282-91 Renal cell carcinoma; see Carcinoma, renal cell Reperfusion injury Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion (Ruixing et al). 2007;149:152-60 Review articles Immune dysfunction in inflammatory bowel disease (Neuman). 2007;149:173-86 Noninvasive assessment of fibrosis in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) (Miele et al). 2007;149:114-25 Nutrigenetics and nutraceuticals: the next wave riding on personalized medicine (Subbiah). 2007;149:55-61 Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis (Lapierre et al). 2007; 149:107-13 Rh-Hr Blood-Group system Prevalence of RHD 1227A and hybrid Rhesus box in the general Chinese population (Yang et al). 2007;149:31-6 Risk factors Adiponectin levels are associated with coronary artery disease across Caucasian and African-American ethnicity (Lu et al). 2007;149:317-23 The role of acetaldehyde in upper digestive tract cancer in alcoholics (Seitz and Meier). 2007;149:293-7 RNA splice sites Hemochromatosis (HFE) gene splice site mutation IVS5⫹1 G/A in North American Vietnamese with and without phenotypic evidence of iron overload (Steiner et al). 2007;149:92-5 S Self efficacy Are provider self-efficacy and attitudes related to cardiovascular prevention associated with better treatment outcomes? (Litaker et al). 2007;149:165-72 Sensitivity and specificity Measurement of extra-pancreatic secretory function by 13Cdipeptide breath test (Ishii et al). 2007;149:298-303 Sesquiterpenes Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53
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Translational Research June 2007
Subject Index
Signal transduction Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells (Chen et al). 2007;149:274-81 Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30 Smad7 protein Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Stem cells Impaired integration of endothelial progenitor cells in capillaries of diabetic wounds is reversible with vascular endothelial growth factor infusion (Singh et al). 2007;149:282-91 Stevens-Johnson syndrome Apoptosis in ibuprofen-induced Stevens-Johnson syndrome (Neuman and Nicar). 2007;149:254-9 SU-011248; see Indoles; Pyrroles Sulfonamides Immunopathogenesis of hypersensitivity syndrome reactions to sulfonamides (Neuman et al). 2007;149:243-53 T Tensile strength New method to prepare autologous fibrin glue on demand (Alston et al). 2007;149:187-95 Tetrathiomolybdate; see Molybdenum Tetrathiotungstate; see Tungsten compounds Th1 cells Immunologic response enhances atherosclerosis—type 1 helper T cell (Th1)-to-type 2 helper T cell (Th2) shift and calcified atherosclerosis in Bacillus Calmette-Guerin (BCG)-treated apolipoprotein E-knockout (apo E⫺/⫺) mice (Shibata et al). 2007;149:62-9 Th2 cells Immunologic response enhances atherosclerosis—type 1 helper T cell (Th1)-to-type 2 helper T cell (Th2) shift and calcified atherosclerosis in Bacillus Calmette-Guerin (BCG)-treated apolipoprotein E-knockout (apo E⫺/⫺) mice (Shibata et al). 2007;149:62-9 Thromboplastin Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30 Tissue factor; see Thromboplastin Tissue inhibitor of metalloproteinases Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms (Nanni et al). 2007;149:137-44 TNP-470; see Sesquiterpenes Transcription factors Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Transferrin Hemochromatosis (HFE) gene splice site mutation IVS5⫹1 G/A in North American Vietnamese with and without phenotypic evidence of iron overload (Steiner et al). 2007;149:92-5
Treatment outcome Are provider self-efficacy and attitudes related to cardiovascular prevention associated with better treatment outcomes? (Litaker et al). 2007;149:165-72 Hemoglobin A1c (HbA1c) predicts future drug treatment for diabetes mellitus: a follow-up study using routine clinical data in a Japanese University hospital (Shimazaki et al). 2007;149: 196-204 Trimetazidine Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia-reperfusion (Ruixing et al). 2007;149:152-60 Tumor necrosis factor-alpha Carvedilol, a nonselective -blocker, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro (Mizuochi et al). 2007;149:223-30 Expression of angiopoietin-1 in osteoblasts and its inhibition by tumor necrosis factor-alpha and interferon-gamma (Kasama et al). 2007;149:265-73 Immunopathogenesis of hypersensitivity syndrome reactions to sulfonamides (Neuman et al). 2007;149:243-53 Tumor suppressor protein p53 Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism (Mauriz et al). 2007;149:46-53 Tungsten compounds Antitumor and antiinflammatory effects of tetrathiotungstate in comparison with tetrathiomolybdate (Hou et al). 2007;149: 260-4 U Umbilical cord Procedure to consistently obtain endothelial and smooth muscle cell cultures from umbilical cord vessels (De Llano et al). 2007;149:1-9 Urinary plasminogen activator Urokinase-type plasminogen activator deficiency (uPA-KO) prevented carotid artery ligation-induced vascular remodeling in mice (Martin-McNulty et al). 2007;149:70-5 Uroporphyrinogen decarboxylase Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP) (Phillips et al). 2007;149:85-91 Uroporphyrinogens Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP) (Phillips et al). 2007;149:85-91 V Variation (Genetics) Genotypic variation in ATP-binding cassette transporter-1 (ABCA1) as contributors to the high and low high-density lipoprotein-cholesterol (HDL-C) phenotype (Mantaring et al). 2007;149:205-10 Vascular endothelial growth factors Impaired integration of endothelial progenitor cells in capillaries of diabetic wounds is reversible with vascular endothelial growth factor infusion (Singh et al). 2007;149:282-91 Vasoconstrictor agents Urokinase-type plasminogen activator deficiency (uPA-KO) prevented carotid artery ligation-induced vascular remodeling in mice (Martin-McNulty et al). 2007;149:70-5
Translational Research Volume 149, Number 6
Subject Index
VEGF; see Vascular endothelial growth factors Ventricular fibrillation Irregularity test for very short electrocardiogram (ECG) signals as a method for predicting a successful defibrillation in patients with ventricular fibrillation (Jagricˇ et al). 2007;149:145-51
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of diabetic wounds is reversible with vascular endothelial growth factor infusion (Singh et al). 2007;149:282-91 WT1 proteins Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42 Z
W Wound healing Impaired integration of endothelial progenitor cells in capillaries
Zinc fingers Transcriptional regulation of podocyte disease (Chugh). 2007; 149:237-42