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Subject index volume 28 (1984)
Mechanisms of Ageing and Development, 28 (1984) 345-349 Elsevier Scientific Publishers Ireland Ltd.
345
MECHANISMS OF AGEING AND DEVELOPMENT SUBJECT INDEX
Volume 28 (1984) Age cholesterol, lipids, membrane fluidity, mitogen response, 123 Age enzyme-linked immtmosorbent assay (ELISA), anti-DNA antibodies, hyperlipidemia, 289
Age enzymes, plasma cholesterol, HDL-cholesterol, survival, 219
Age bone mineral content, smoking, body weight, 273 Ageing chromatin, histories, non-histone proteins, DNA, 139 Ageing fibroblasts, eiectrophoresis, peptide mapping, fibronectin, 83 Ageing health, human immunogerontology, 47 Ageing longevity, gene frequencies, heterozygosity, 261 Ageing renal artery, dopamine receptors, 41 Ageing superoxide dismutase, calalase, lipid peroxidation, liver, mouse, 297 Ageing elastin, elastases, artery, skin, extraeeilular matrix, connective tissues, 155 Aging glycogen synthase, glycogen phosphorylase, glycogen metabolism, liver, glucose tolerance, 13
Aging homogeneous immunoglobulins, paraproteins, B-cell proliferative disorders, 167 Aging lens, glyceraldehyde 3-phosphate dehydrogenase, 187 0047-6374/84/$03.00 Printed and Published in Ireland
Aging mice sequential multiple thymus grafting, immune functions, life expectancy, 111 Aging triiodothyronine, epinephrine, fat ceils, glycerol release, 337 Aldosterone system healthy elderly, body fluids, endocrine system, plasma volume, renin angiotensin, 315 Animal models of aging longitudinal study, maximum lifespan prolongation, multiple pathology, 249 A nti-DNA antibodies enzyme-linked immunosorbent assay (ELISA), hyperlipidemia, age, 289 Anti-hypertensive therapy elderly, effect on cerebral function, 229 Arterial impedance myocardium ageing, harmonic analysis, arterial pressure wave, 305 Arterial pressure wave myocardium ageing, arterial impedance, harmonic analysis, 305 Arteriosclerosis in children high density lipoprotein cholesterol, progeria, 243 Artery elastin, elastases, aging, skin, extraceUular matrix, connective tissues, 155 B-eeU proliferative disorders homogeneous immunoglobulins, paraproteins, ageing, 167 Body fluids healthy elderly, endocrine system, plasma volume, renin angiotensin, aldosterone system, 315 Body weight ageing bone mineral content, smoking, 273 Bone mineral content ageing, smoking, body weight, 273 © 1984 Elsevier Scientific Publishers Ireland Ltd.
346 Brain ageing respiratory rate, mitochondrial structure, insects, Calliphora, 237
Calliphora brain ageing, respiratory rate, mitochondrial structure, insects, 237 Caloric restriction developmental program, programmed senescence, control of senescence, 23 Catalase superoxide dismutase, lipid peroxidation, liver, mouse, ageing, 297 Cellular aging Paramecium tetraurelia, microinjections, 57 Cell aging programmed theory, cytogerontology, chromosomes, 177 Centrophenoxine membrane hypothesis of aging, synaptosomes, protein molecular weights and aging, membrane composition and aging, intermolecular cross-linking, 171 Cholesterol age, lipids, membrane fluidity, mitogen response, 123 Chromatin histones, non-histone proteins, DNA, ageing, 139 Chromosomes cell aging, programmed theory, cytogerontology, 177 Chromsomes heterogenous structure, key factor in ageing, 279 Connective tissues elastin, elastases, aging, artery, skin, extracellular matrix, 155 Control of senescence developmental program, programmed senescence, caloric restriction, 23 Crowding motor activity, maze-learning, mortality rates, rat, 325 Cyclic AMP thyroid secretion, lysosomes, thyroid ageing, 1 Cytogerontology cell aging, programmed theory, chromosomes, 177 Developmental program programmed senescence, control of senescence, caloric restriction, 23
Dill* i, i,,;iation 1" cells, thymic-neuroendocrine axis, phytohemagglutinin, 193 DNA chromatin, histones, non-histone proteins, ageing, 139 Dopamine receptors ageing, renal artery, 41 Effect on cerebral function anti-hypertensive therapy, elderly, 229 Elastases elastin, aging, artery, skin, extracellular matrix, connective tissues, 155 Elastin elastases, aging, artery, skin, extracellular matrix, connective tissues, 155 Elderly anti-hypertensive therapy, effect on cerebral function, 229 Electrophoresis fibroblast, ageing peptide mapping, fibronectin, 83 Endocrine system healthy elderly, body fluids, plasma volume, renin angiotensin, aldosterone system, 315 t3-Enolase human skeletal muscle, type of fibers, size and number, 99 Enzymeqinked immunosorbent assay (ELISA) anti-DNA antibodies, hyperlipidemia, age, 289 Enzymes plasma cholesterol, HDL-cholesterol, age, survival, 219 Epinephrine triiodothyronine, fat cells, glycerol release, aging, 337 Extracellular matrix elastin, elastases, aging, artery, skin, connective tissues, 155 Fat cells triiodothyronine, epinephrine, glycerol release, aging, 337 Fibroblast ageing, electrophoresis, peptide mapping, fibronectin, 83 Fibronectin fibroblast, ageing, electrophoresis, peptide mapping, 83 Gene frequencies ageing, longevity, heterozygosity, 261
347 Glucose tolerance ageing, glycogen synthase, glycogen phosphorylase, glycogen metabolism, liver, 13 Glyceraldehyde 3-phosphate dehydrogenase lens, aging, 187 Glycerol release triiodothyronine, epinephrine, fat cells, aging, 337 Glycogen metabolism aging, glycogen synthase, glycogen phosphorylase, liver, glucose tolerance, 13 Glycogen phosphorylase aging, glycogen synthase, glycogen metabolism, liver, glucose tolerance, 13 Glycogen synthase aging, glycogen phosphorylase, glycogen metabolism, liver, glucose tolerance, 13 Harmonic analysis myocardium ageing, arterial impedance, arterial pressure wave, 305 HDL-cholesterol enzymes, plasma cholesterol, age, survival, 219 Health ageing, human immunogerontology, 47 Helathy elderly body fluids, endocrine system, plasma volume, renin angiotensin, aldosterone system, 315 Heterogenous structure chromosomes, key factor in aging, 279 Heterozygosity ageing, longevity, gene frequencies, 261 High density lipoprotein cholesterol progeria, arteriosclerosis in children, 243 Histones chromatin, non-histone proteins, DNA, ageing, 139 Homogeneous immunoglobulins paraproteins, B-cell proliferative disorders, aging, 167 Human immunogerontology ageing, health, 47 Human skeletal muscle type of fibers, size and number, #-enolase, 99 Hyperlipidemia enzyme-linked immunosorbent assay (ELISA), anti-DNA antibodies, age, 289 la ÷ macrophages immunological aging, syngeneic host-versus. graft reaction, 67
Immune functions sequential multiple thumus grafting, life expectancy, aging mice, 111 Immunological aging Ia+ macrophages, syngeneic host-versus-graft reaction, 67 Insects brain ageing, respiratory rate, mitochondrial structure, Calliphora, 237 lntermolecular cross-linking membrane hypothesis of aging, synaptosomes, protein molecular weights and aging, centrophenoxine, membrane composition and aging, 171 Key factor in aging chromosomes, heterogenous structure, 279 Lens glyceraldehyde 3-phosphate dehydrogenase, ageing, 187 Life expectancy sequential multiple thymus grafting, immune functions, aging mice, 111 Lipid peroxidation superoxide dismutase, catalase, liver, mouse, ageing, 297 Lipids age, cholesterol, membrane fluidity, mitogen response, 123 Liver superoxide dismutase, calalase, lipid peroxidarien, mouse, ageing, 297 Liver aging, glycogen synthase, glycogen phosphorylase, glycogen metabolism, glucose tolerance, 13 Longevity ageing, gene frequencies, heterozygosity, 261 Longitudinal study maximum llfespan prolongation, multiple pathology, animal models of aging, 249 Lysosomes thyroid secretion, cyclic AMP, thyroid ageing, 1 Maximum lifespan prolongation longitudinal study, multiple pathology, animal models of aging, 249 Maze-learning crowding, motor activity, mortality rates, rat, 325 Membrane composition and aging membrane hypothesis of aging, synapto-
348 somes, protein molecular weights and aging, centrophenoxine, intermolecular cross-linking, 171 Membrane fluidity age, cholesterol, lipids, mitogen response, 123 Membrane hypothesis of aging synaptosomes, protein molecular weights and aging, centrophenoxine, membrane composition and aging, intermolecular crosslinking, 171 Microinjections cellular aging, Paramecium tetraurelia, 57 Mitochondrial structure brain ageing, respiratory rate, insects, Calliphora, 237 Mitogen response age, cholesterol, llpids, membrane fluidity, 123 Mortality rates crowding, motor activity, maze-learning, rat, 325 Motor activity crowding, maze-learning, mortality, rates, rat, 325 Mouse superoxide dismutase, catalase, lipid peroxidation, liver, ageing, 297 Multiple pathology longitudinal study, maximum lifespan prolongation, animal models of aging, 249 Myocardium ageing arterial impedance, harmonic analysis, arterial pressure wave, 305 Non-histone proteins chromatin, histones, DNA, ageing, 139
Paramecium tetraurelia cellular aging, microinjections, 57 Paraproteins homogeneous immunoglobulins, B-cell proliferative disorders, aging, 167 Peptide mapping fibroblast, ageing, electrophoresis, fibronectin, 83 Phytohemagglutinin T cells, differentiation, thymic-neuroendocrine axis, 193 Plasma cholesterol enzymes, HDL-cholesterol, age, survival, 219 Plasma volume healthy elderly, body fluids, endocrine
system, renin angiotensin, aldosterone system, 315 Progeria high density lipoprotein cholesterol, arteriosclerosis in children, 243 Programmed senescence developmental program, control of senescence, caloric restriction, 23 Programmed theory cell aging, cytogerontology, chromosomes, 177 Protein molecular weights and aging membrane hypothesis of aging, synaptosomes, centrophenoxine, membrane composition and aging, intermolecular crosslinking, 171 Rat crowding, motor activity, maze-learning, mortality rates, 325 Renal artery ageing, dopamine receptors, 41 Renin angiotensin healthy elderly, body fluids, endocrine system, plasma volume, aldosterone system, 315 Respiratory rate brain ageing, mitochondrial structure, insects, Calliphora, 237 Sequential multiple thymus grafting immune functions, life expectancy, aging mice, 111 Size and number human skeletal muscle, type of fibers, B-enolase, 99 Skin elastin, elastases, aging, artery, extraceUular matrix, connective tissues, 155 Smoking ageing, bone mineral content, body weight, 273 Superoxide dismutase catalase, lipid peroxidation, liver, mouse, ageing, 297 Survival enzymes, plasma cholesterol, HDL-cholesterol, age, 219 Synaptosomes membrane hypothesis of aging, protein molecular weights and aging, centrophenoxine, membrane composition and aging, intermolecular cross-linking, 171
349 Syngeneic host-versus-graft reaction immunological aging, la ÷ macrophages, 67 T cells differentiation, thymic-neuroendocrine axis, phytohemagglutinin, 193 Thymic-neuroendocrine axis T ceUs, differentiation, phytohemagglutinin, 193
Thyroid ageing thyroid secretion, lysosomes, cyclic AMP, 1 Thyroid secretion lysosomes, cyclic AMP, throid ageing, 1 Trliodothyronine epinephrine, fat cells, glycerol release, aging, 337 Type of fibers human skeletal muscle, size and nhmber, ~-enoiase, 99
345
MECHANISMS OF AGEING AND DEVELOPMENT SUBJECT INDEX
Volume 28 (1984) Age cholesterol, lipids, membrane fluidity, mitogen response, 123 Age enzyme-linked immtmosorbent assay (ELISA), anti-DNA antibodies, hyperlipidemia, 289
Age enzymes, plasma cholesterol, HDL-cholesterol, survival, 219
Age bone mineral content, smoking, body weight, 273 Ageing chromatin, histories, non-histone proteins, DNA, 139 Ageing fibroblasts, eiectrophoresis, peptide mapping, fibronectin, 83 Ageing health, human immunogerontology, 47 Ageing longevity, gene frequencies, heterozygosity, 261 Ageing renal artery, dopamine receptors, 41 Ageing superoxide dismutase, calalase, lipid peroxidation, liver, mouse, 297 Ageing elastin, elastases, artery, skin, extraeeilular matrix, connective tissues, 155 Aging glycogen synthase, glycogen phosphorylase, glycogen metabolism, liver, glucose tolerance, 13
Aging homogeneous immunoglobulins, paraproteins, B-cell proliferative disorders, 167 Aging lens, glyceraldehyde 3-phosphate dehydrogenase, 187 0047-6374/84/$03.00 Printed and Published in Ireland
Aging mice sequential multiple thymus grafting, immune functions, life expectancy, 111 Aging triiodothyronine, epinephrine, fat ceils, glycerol release, 337 Aldosterone system healthy elderly, body fluids, endocrine system, plasma volume, renin angiotensin, 315 Animal models of aging longitudinal study, maximum lifespan prolongation, multiple pathology, 249 A nti-DNA antibodies enzyme-linked immunosorbent assay (ELISA), hyperlipidemia, age, 289 Anti-hypertensive therapy elderly, effect on cerebral function, 229 Arterial impedance myocardium ageing, harmonic analysis, arterial pressure wave, 305 Arterial pressure wave myocardium ageing, arterial impedance, harmonic analysis, 305 Arteriosclerosis in children high density lipoprotein cholesterol, progeria, 243 Artery elastin, elastases, aging, skin, extraceUular matrix, connective tissues, 155 B-eeU proliferative disorders homogeneous immunoglobulins, paraproteins, ageing, 167 Body fluids healthy elderly, endocrine system, plasma volume, renin angiotensin, aldosterone system, 315 Body weight ageing bone mineral content, smoking, 273 Bone mineral content ageing, smoking, body weight, 273 © 1984 Elsevier Scientific Publishers Ireland Ltd.
346 Brain ageing respiratory rate, mitochondrial structure, insects, Calliphora, 237
Calliphora brain ageing, respiratory rate, mitochondrial structure, insects, 237 Caloric restriction developmental program, programmed senescence, control of senescence, 23 Catalase superoxide dismutase, lipid peroxidation, liver, mouse, ageing, 297 Cellular aging Paramecium tetraurelia, microinjections, 57 Cell aging programmed theory, cytogerontology, chromosomes, 177 Centrophenoxine membrane hypothesis of aging, synaptosomes, protein molecular weights and aging, membrane composition and aging, intermolecular cross-linking, 171 Cholesterol age, lipids, membrane fluidity, mitogen response, 123 Chromatin histones, non-histone proteins, DNA, ageing, 139 Chromosomes cell aging, programmed theory, cytogerontology, 177 Chromsomes heterogenous structure, key factor in ageing, 279 Connective tissues elastin, elastases, aging, artery, skin, extracellular matrix, 155 Control of senescence developmental program, programmed senescence, caloric restriction, 23 Crowding motor activity, maze-learning, mortality rates, rat, 325 Cyclic AMP thyroid secretion, lysosomes, thyroid ageing, 1 Cytogerontology cell aging, programmed theory, chromosomes, 177 Developmental program programmed senescence, control of senescence, caloric restriction, 23
Dill* i, i,,;iation 1" cells, thymic-neuroendocrine axis, phytohemagglutinin, 193 DNA chromatin, histones, non-histone proteins, ageing, 139 Dopamine receptors ageing, renal artery, 41 Effect on cerebral function anti-hypertensive therapy, elderly, 229 Elastases elastin, aging, artery, skin, extracellular matrix, connective tissues, 155 Elastin elastases, aging, artery, skin, extracellular matrix, connective tissues, 155 Elderly anti-hypertensive therapy, effect on cerebral function, 229 Electrophoresis fibroblast, ageing peptide mapping, fibronectin, 83 Endocrine system healthy elderly, body fluids, plasma volume, renin angiotensin, aldosterone system, 315 t3-Enolase human skeletal muscle, type of fibers, size and number, 99 Enzymeqinked immunosorbent assay (ELISA) anti-DNA antibodies, hyperlipidemia, age, 289 Enzymes plasma cholesterol, HDL-cholesterol, age, survival, 219 Epinephrine triiodothyronine, fat cells, glycerol release, aging, 337 Extracellular matrix elastin, elastases, aging, artery, skin, connective tissues, 155 Fat cells triiodothyronine, epinephrine, glycerol release, aging, 337 Fibroblast ageing, electrophoresis, peptide mapping, fibronectin, 83 Fibronectin fibroblast, ageing, electrophoresis, peptide mapping, 83 Gene frequencies ageing, longevity, heterozygosity, 261
347 Glucose tolerance ageing, glycogen synthase, glycogen phosphorylase, glycogen metabolism, liver, 13 Glyceraldehyde 3-phosphate dehydrogenase lens, aging, 187 Glycerol release triiodothyronine, epinephrine, fat cells, aging, 337 Glycogen metabolism aging, glycogen synthase, glycogen phosphorylase, liver, glucose tolerance, 13 Glycogen phosphorylase aging, glycogen synthase, glycogen metabolism, liver, glucose tolerance, 13 Glycogen synthase aging, glycogen phosphorylase, glycogen metabolism, liver, glucose tolerance, 13 Harmonic analysis myocardium ageing, arterial impedance, arterial pressure wave, 305 HDL-cholesterol enzymes, plasma cholesterol, age, survival, 219 Health ageing, human immunogerontology, 47 Helathy elderly body fluids, endocrine system, plasma volume, renin angiotensin, aldosterone system, 315 Heterogenous structure chromosomes, key factor in aging, 279 Heterozygosity ageing, longevity, gene frequencies, 261 High density lipoprotein cholesterol progeria, arteriosclerosis in children, 243 Histones chromatin, non-histone proteins, DNA, ageing, 139 Homogeneous immunoglobulins paraproteins, B-cell proliferative disorders, aging, 167 Human immunogerontology ageing, health, 47 Human skeletal muscle type of fibers, size and number, #-enolase, 99 Hyperlipidemia enzyme-linked immunosorbent assay (ELISA), anti-DNA antibodies, age, 289 la ÷ macrophages immunological aging, syngeneic host-versus. graft reaction, 67
Immune functions sequential multiple thumus grafting, life expectancy, aging mice, 111 Immunological aging Ia+ macrophages, syngeneic host-versus-graft reaction, 67 Insects brain ageing, respiratory rate, mitochondrial structure, Calliphora, 237 lntermolecular cross-linking membrane hypothesis of aging, synaptosomes, protein molecular weights and aging, centrophenoxine, membrane composition and aging, 171 Key factor in aging chromosomes, heterogenous structure, 279 Lens glyceraldehyde 3-phosphate dehydrogenase, ageing, 187 Life expectancy sequential multiple thymus grafting, immune functions, aging mice, 111 Lipid peroxidation superoxide dismutase, catalase, liver, mouse, ageing, 297 Lipids age, cholesterol, membrane fluidity, mitogen response, 123 Liver superoxide dismutase, calalase, lipid peroxidarien, mouse, ageing, 297 Liver aging, glycogen synthase, glycogen phosphorylase, glycogen metabolism, glucose tolerance, 13 Longevity ageing, gene frequencies, heterozygosity, 261 Longitudinal study maximum llfespan prolongation, multiple pathology, animal models of aging, 249 Lysosomes thyroid secretion, cyclic AMP, thyroid ageing, 1 Maximum lifespan prolongation longitudinal study, multiple pathology, animal models of aging, 249 Maze-learning crowding, motor activity, mortality rates, rat, 325 Membrane composition and aging membrane hypothesis of aging, synapto-
348 somes, protein molecular weights and aging, centrophenoxine, intermolecular cross-linking, 171 Membrane fluidity age, cholesterol, lipids, mitogen response, 123 Membrane hypothesis of aging synaptosomes, protein molecular weights and aging, centrophenoxine, membrane composition and aging, intermolecular crosslinking, 171 Microinjections cellular aging, Paramecium tetraurelia, 57 Mitochondrial structure brain ageing, respiratory rate, insects, Calliphora, 237 Mitogen response age, cholesterol, llpids, membrane fluidity, 123 Mortality rates crowding, motor activity, maze-learning, rat, 325 Motor activity crowding, maze-learning, mortality, rates, rat, 325 Mouse superoxide dismutase, catalase, lipid peroxidation, liver, ageing, 297 Multiple pathology longitudinal study, maximum lifespan prolongation, animal models of aging, 249 Myocardium ageing arterial impedance, harmonic analysis, arterial pressure wave, 305 Non-histone proteins chromatin, histones, DNA, ageing, 139
Paramecium tetraurelia cellular aging, microinjections, 57 Paraproteins homogeneous immunoglobulins, B-cell proliferative disorders, aging, 167 Peptide mapping fibroblast, ageing, electrophoresis, fibronectin, 83 Phytohemagglutinin T cells, differentiation, thymic-neuroendocrine axis, 193 Plasma cholesterol enzymes, HDL-cholesterol, age, survival, 219 Plasma volume healthy elderly, body fluids, endocrine
system, renin angiotensin, aldosterone system, 315 Progeria high density lipoprotein cholesterol, arteriosclerosis in children, 243 Programmed senescence developmental program, control of senescence, caloric restriction, 23 Programmed theory cell aging, cytogerontology, chromosomes, 177 Protein molecular weights and aging membrane hypothesis of aging, synaptosomes, centrophenoxine, membrane composition and aging, intermolecular crosslinking, 171 Rat crowding, motor activity, maze-learning, mortality rates, 325 Renal artery ageing, dopamine receptors, 41 Renin angiotensin healthy elderly, body fluids, endocrine system, plasma volume, aldosterone system, 315 Respiratory rate brain ageing, mitochondrial structure, insects, Calliphora, 237 Sequential multiple thymus grafting immune functions, life expectancy, aging mice, 111 Size and number human skeletal muscle, type of fibers, B-enolase, 99 Skin elastin, elastases, aging, artery, extraceUular matrix, connective tissues, 155 Smoking ageing, bone mineral content, body weight, 273 Superoxide dismutase catalase, lipid peroxidation, liver, mouse, ageing, 297 Survival enzymes, plasma cholesterol, HDL-cholesterol, age, 219 Synaptosomes membrane hypothesis of aging, protein molecular weights and aging, centrophenoxine, membrane composition and aging, intermolecular cross-linking, 171
349 Syngeneic host-versus-graft reaction immunological aging, la ÷ macrophages, 67 T cells differentiation, thymic-neuroendocrine axis, phytohemagglutinin, 193 Thymic-neuroendocrine axis T ceUs, differentiation, phytohemagglutinin, 193
Thyroid ageing thyroid secretion, lysosomes, cyclic AMP, 1 Thyroid secretion lysosomes, cyclic AMP, throid ageing, 1 Trliodothyronine epinephrine, fat cells, glycerol release, aging, 337 Type of fibers human skeletal muscle, size and nhmber, ~-enoiase, 99