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Test–Retest Reliability of Corticospinal Excitability of Rectus Femoris With TMS in Able-bodied Adults
Research Posters Conclusion/Discussion: The utilization of telemetry sensing technology could be considered a useful strategy to improve wound monitoring, thus potentially improving clinical outcomes, decreasing infection rates and hospitalization length of stay. Current barriers to the use of these systems are the lack of human studies and the limitations of the technology itself in terms of cost and implementation to health care facilities. Key Words: Wound Healing, Telemetry, Rehabilitation Disclosures: None.
Research Poster 324215 TesteRetest Reliability of Corticospinal Excitability of Rectus Femoris With TMS in Ablebodied Adults Prasath Jayakaran (University of Otago), Jonathan Shemmell, Efri Hendri, MPhty (Otago), Alexander Nowicky, Leigh Hale Research Objectives: To determine the relative and absolute reliability of corticospinal excitability of rectus femoris in healthy adults, as measured by stimulus-response (SR) curve and centre of gravity (COG) of cortical maps. Design: Repeated measures observational study. Setting: University motor control laboratory. Participants: Fourteen healthy volunteers (38.5 11.6 years) completed two sessions of transcranial magnetic stimulation (TMS) procedures. Interventions: SR curve was obtained from rectus femoris by applying TMS at intensities from 90% to 160% of active motor threshold (AMT). Cortical maps were obtained from 30 sites over the primary motor cortex, at 130% of AMT. A custom-designed plastic grid cap was used to assist placement of coils. Maximum voluntary contraction (MVC) was determined using Biodex Isokinetic system and 15% 1% of MVC in the target muscle was maintained by the participants. Real-time visual feedback of MVC was provided to facilitate voluntary activation during each TMS procedure. Main Outcome Measure(s): X-intercept and R-square of the SR curve. COG of cortical maps calculated as a weighted average of the MEP peakto-peak amplitude of 30 sites. Results: Intraclass correlation coefficient (ICC) was excellent (ICC>0.80) for x-intercept of the SR curve and fair for R-square of linear model (ICCZ0.40 and 0.45). The percentage of standard error of measurement ranged from 9.88 to 22.64% in both hemispheres. The ICCs were poor to fair (ICCZ 0.20-0.57) for COG positions during cortical mapping, with high standard error of measurement (24.66 to 44.02%). Conclusion/Discussion: This test-retest procedure demonstrated that the SR curve for TMS targeting the rectus femoris muscle has acceptable relative reliability while the mapping procedure did not. In addition, the variability of the x-intercept was minimal across testing session, indicating the SR curve as a reliable measure of cortical excitability of rectus femoris. Key Words: Lower Limb Muscles, Cortical Excitability, Transcranial Magnetic Stimulation, Neuroplasticity Disclosures: None. Research Poster 304826 The Capacity to Work or Study After Rehabiltiative Psychotherapy - A Register-Based Cohort Study Annamari Tuulio-Henriksson (the Social Insurance Institution (Kela) Kela research), Tuula Toikka, Pekka Heino, Tanja Laukkala
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e115 Research Objectives: To investigate the capacity to work or study in a cohort of 13703 persons who had received rehabilitative psychotherapy (13 years) one year after the cessation of the psychotherapy. The Finnish Social Insurance Institution (Kela) reimburses costs of rehabilitative psychotherapy for 16-67 year-old persons who have a diagnosed mental disorder that presents a risk to their capacity to work or study. Design: A register-based cohort study. Setting: The cohort consisted of persons referred to long-term rehabilitation psychotherapy after at least three-month treatment for a mental health disorder during years 2011-2012 and the cohort was followed until 31.12.2015. Participants: 10552 women and 3151 men with a mental health disorder that presented a risk to working capacity (two major groups ICD-10 F3039, mood disorders 61% and F40-48, neurotic disorders 32%). Interventions: Long-term rehabilitative psychotherapy. A maximum of 200 sessions per 3 years are covered. Main Outcome Measure(s): The capacity to work or study and the use of psychotrophic medication one year after psychotherapy. Results: At the time of the application for rehabilitation 96% were working, studying, on sick leave or unemployed. One year after the psychotherapy 82% were working, studying, on sick leave or unemployed. For 12%, data on working situation was missing (includes e.g. students without student benefits). 6% received a disability pension. In the year of the application 74% had psychotropic medication and at the one-year followup 52% had psychotropic medication. Conclusion/Discussion: Our results suggest a similar trend as the results from an earlier Finnish study in which 81% were working, studying, on sick leave or unemployed and 9% had a disability pension three years after psychotherapy. Key Words: Rehabilitative Psychotherapy, Depression, Anxiety Disclosures: None.
Research Poster 310345 The Cerebral Palsy Adult Transition Study: Metabolic Syndrome and Cardiovascular Disease Risk Factors Prevalence Patricia Heyn (University of Colorado Anschutz Medical Campus), Alex Tagawa, Zhaoxing Pan, James Carollo Research Objectives: Determine the prevalence of metabolic syndrome (MetSyn) and cardiovascular disease (CVD) risk factor for adults diagnosed with cerebral palsy (CP). Design: A prospective cross-sectional cohort study evaluating current associations between walking and physical ability, cognition, overall health status, and QoL. Setting: Nationally accredited clinical motion lab at a regional children’s hospital. Participants: This prospective study recruited subjects 18 year or older diagnosed with CP, who have been seen at the clinical motion lab, and have had at least one full instrumented gait analysis at this facility. A total of 72 subjects (47.2% female, 52.8% male, mean age 24.45.29) were recruited. Interventions: N/A. Main Outcome Measure(s): BMI and other health status measurements were used to determine the prevalence of MetSyn using the definitions created by the World Health Organization (WHO), the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATPIII), and the International Diabetes Foundation (IDF). Framingham CVD 30-year risk factors were calculated using health status measurements.
Research Poster 324215 TesteRetest Reliability of Corticospinal Excitability of Rectus Femoris With TMS in Ablebodied Adults Prasath Jayakaran (University of Otago), Jonathan Shemmell, Efri Hendri, MPhty (Otago), Alexander Nowicky, Leigh Hale Research Objectives: To determine the relative and absolute reliability of corticospinal excitability of rectus femoris in healthy adults, as measured by stimulus-response (SR) curve and centre of gravity (COG) of cortical maps. Design: Repeated measures observational study. Setting: University motor control laboratory. Participants: Fourteen healthy volunteers (38.5 11.6 years) completed two sessions of transcranial magnetic stimulation (TMS) procedures. Interventions: SR curve was obtained from rectus femoris by applying TMS at intensities from 90% to 160% of active motor threshold (AMT). Cortical maps were obtained from 30 sites over the primary motor cortex, at 130% of AMT. A custom-designed plastic grid cap was used to assist placement of coils. Maximum voluntary contraction (MVC) was determined using Biodex Isokinetic system and 15% 1% of MVC in the target muscle was maintained by the participants. Real-time visual feedback of MVC was provided to facilitate voluntary activation during each TMS procedure. Main Outcome Measure(s): X-intercept and R-square of the SR curve. COG of cortical maps calculated as a weighted average of the MEP peakto-peak amplitude of 30 sites. Results: Intraclass correlation coefficient (ICC) was excellent (ICC>0.80) for x-intercept of the SR curve and fair for R-square of linear model (ICCZ0.40 and 0.45). The percentage of standard error of measurement ranged from 9.88 to 22.64% in both hemispheres. The ICCs were poor to fair (ICCZ 0.20-0.57) for COG positions during cortical mapping, with high standard error of measurement (24.66 to 44.02%). Conclusion/Discussion: This test-retest procedure demonstrated that the SR curve for TMS targeting the rectus femoris muscle has acceptable relative reliability while the mapping procedure did not. In addition, the variability of the x-intercept was minimal across testing session, indicating the SR curve as a reliable measure of cortical excitability of rectus femoris. Key Words: Lower Limb Muscles, Cortical Excitability, Transcranial Magnetic Stimulation, Neuroplasticity Disclosures: None. Research Poster 304826 The Capacity to Work or Study After Rehabiltiative Psychotherapy - A Register-Based Cohort Study Annamari Tuulio-Henriksson (the Social Insurance Institution (Kela) Kela research), Tuula Toikka, Pekka Heino, Tanja Laukkala
www.archives-pmr.org
e115 Research Objectives: To investigate the capacity to work or study in a cohort of 13703 persons who had received rehabilitative psychotherapy (13 years) one year after the cessation of the psychotherapy. The Finnish Social Insurance Institution (Kela) reimburses costs of rehabilitative psychotherapy for 16-67 year-old persons who have a diagnosed mental disorder that presents a risk to their capacity to work or study. Design: A register-based cohort study. Setting: The cohort consisted of persons referred to long-term rehabilitation psychotherapy after at least three-month treatment for a mental health disorder during years 2011-2012 and the cohort was followed until 31.12.2015. Participants: 10552 women and 3151 men with a mental health disorder that presented a risk to working capacity (two major groups ICD-10 F3039, mood disorders 61% and F40-48, neurotic disorders 32%). Interventions: Long-term rehabilitative psychotherapy. A maximum of 200 sessions per 3 years are covered. Main Outcome Measure(s): The capacity to work or study and the use of psychotrophic medication one year after psychotherapy. Results: At the time of the application for rehabilitation 96% were working, studying, on sick leave or unemployed. One year after the psychotherapy 82% were working, studying, on sick leave or unemployed. For 12%, data on working situation was missing (includes e.g. students without student benefits). 6% received a disability pension. In the year of the application 74% had psychotropic medication and at the one-year followup 52% had psychotropic medication. Conclusion/Discussion: Our results suggest a similar trend as the results from an earlier Finnish study in which 81% were working, studying, on sick leave or unemployed and 9% had a disability pension three years after psychotherapy. Key Words: Rehabilitative Psychotherapy, Depression, Anxiety Disclosures: None.
Research Poster 310345 The Cerebral Palsy Adult Transition Study: Metabolic Syndrome and Cardiovascular Disease Risk Factors Prevalence Patricia Heyn (University of Colorado Anschutz Medical Campus), Alex Tagawa, Zhaoxing Pan, James Carollo Research Objectives: Determine the prevalence of metabolic syndrome (MetSyn) and cardiovascular disease (CVD) risk factor for adults diagnosed with cerebral palsy (CP). Design: A prospective cross-sectional cohort study evaluating current associations between walking and physical ability, cognition, overall health status, and QoL. Setting: Nationally accredited clinical motion lab at a regional children’s hospital. Participants: This prospective study recruited subjects 18 year or older diagnosed with CP, who have been seen at the clinical motion lab, and have had at least one full instrumented gait analysis at this facility. A total of 72 subjects (47.2% female, 52.8% male, mean age 24.45.29) were recruited. Interventions: N/A. Main Outcome Measure(s): BMI and other health status measurements were used to determine the prevalence of MetSyn using the definitions created by the World Health Organization (WHO), the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATPIII), and the International Diabetes Foundation (IDF). Framingham CVD 30-year risk factors were calculated using health status measurements.