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The biology and medicine of signal transduction advances in 2nd messenger and phosphoprotein research
488
Book Reviews
and all the chapters hang together. Both theory and practical work on MAb is given. It deals with the immune response; hybridoma technology; factors affecting successful hybridoma production; selection of MAb-secreting hybridoma cell lines; large scale production of MAb h vitro; diversity in application of MAb and hybridoma technology (identification of viruses, antigenic variation in viruses, leukocyte markers, lymphocyte helper and suppressor factors, diagnosis and analysis of tumor antigens, identification of bacteria and parasites, identification of cell lines).
osmotic pressure and ionic composition to be derived from marine forms whilst the cyclophoridae terrestrial snails seem to have used the fresh water route. Similar evidence indicates that the woodlice came from a marine ancestor not a fresh water one. The book also discusses problems of terrestrial versus aquatic habitats; muddy and shore life; saltmarshes and mangrove swamps; terrestrial adaptations. It is very interesting to see the physiological evidence being used to interpret ecological adaptations. Neurobiology of Myrih e&&s-Edited 312 pp. 1990. Manchester University
by G. B. STEFANO. Press, Manchester.
Structures and Fuoctiomv of tbe Low AtUnity Fe ReceptorsEditor W. H. FRIDMAN.258 pp. 1990. S. Karger Basel. S.Fr
$75.
215 DM 257 $143.50.
Myrilus (the edible mussel) has been studied in particular for the properties of its catch muscle where the muscle can remain contracted at a specific length for hours with minimal energy expenditure. Myrilus is also useful for studying other physiological/pharmacological activities and these are discussed in the present volume. The chapters deal with; growth and environmental responsiveness; monoamine and opioid localization; neurotransmitters; CAMP; modulators; thermal acclimation during monoamine axonal transport; autoregulation; ageing.
Receptors for the Fc region of immunoglobulins mediate interactions between cells and immunoglobulins of different isotypes. The high affinity Fc receptors for IgE mediates degranulation of mast cells and basophils. The low affinity Fc receptors for IgG and IgE are expressed on lymphocytes, macrophages, polymorphonuclear cells and mast cells. They trigger killer cells to destroy Ig sensitized target cells; trigger eosinophils to produce. toxins against parasites; mediates phagocytosis of opsonised particles. This volume deals with the structure of Fc receptors for IgG; murine type Fc receptors; human FceRII; regulation of FceR2; eosinophil effector function; targeting and activation of cytotoxic lymphocytes; mononuclear cell cytotoxicity. It gets more like Starwars every day!
The Biology amI Medicine of Signal TrauaduetIon-Edited by Y. NISHIZUKA,M. ENDOand C. TANAKA.Advances in 2nd Messenger and Plwepboprotein Reaearcb. Vol. 24. 750 pp. 1990. Raven Press, New York. $99. This book contains the proceedings of a conference held in Kobe, Japan, October 1989. There are 90 papers. The topics include; receptors (adrenergic, ACh); DNA homology screening; ionic channels; G proteins; adenylate cyclase; PKC and CaMK; calcium entry and release; calmodulin; IP3, phospholipase C; tryrosine kinase; insulin receptor; receptor crosstalk, EDRF; calpain. All the popular topics are here.
Neurotrausmitters In Embryogenesis-G. A. BUZNIKOV. Translated from the Russian by AN~I-IONY BASTOW.526 pp. 1990. Harwood Academic Publishers, New York. $250; SAS price S150. Various transmitters such as acetylcholine, catecholamines, indolealkylamines and gangliosides have effects on marine invertebrate embryos even before the nervous system has developed. They can affect cell division and cleavage, intercellular reactions, protein synthesis, and cell differentiation. There are two additional chapters; one by J. M. Lauder on transmitters and morphogenesis, and the other by S. B. Kater and P. G. Haydon on transmitter regulation of neurite growth, cone motility and synaptogenesis. CardiovascuIar Physiology-W. R. MILNOR.501 pp. 1990. Oxford University Press, New York. $37.95.
This single author textbook is designed for medical students and also as a reference book for more advanced readers. There is a list of those sections necessary for the first year medical course. The chapters are; the circulatory system; normal state of the circulation; properties of cardiac cells; lhsentials of Medical Microbiology. 4th Edition.-By W. A. VOLK, D. C. BENJAMIN,R. J. KADNERand J. T. PARSONS. the heart as a pump; electrical activity of the heart; principles of hemodynamics; cardiovascular control system; 803 pp. 1990. J. B. Lippincott, Philadelphia. Paperback autonomic and peripheral control; regulation of vascular $37.50. smooth muscle; capillary and lymphatic systems; regional circulations; blood; methods of measurement. Each chapter The fourth edition of this interesting, informative and is followed by references to reviews and to research papers. readable textbook has had the chapters brought up to date; The text is clearly written and the book is a good supplement 150 new or revised illustrations; has more on AIDS, cancer to those who find the standard texts too brief, or the major and the molecular biology approach to diseases. The main handbooks too complicated. topics are immunology; bacterial physiology and genetics; bacteria and fungi; virology; medical parasitology. Each chapter also has references to journals and to other books. Noradrewrgic Neurons-By M. FILLENZ.238 pp. 1990 CamVery good value for money. bridge University Press, Cambridge. Wt.50 (hardback); $19.95 (paperback). Tbe Terrestrial Invasion; An Ecopbysiological Approach to the thighs of Land A&u&-By C. LITTLE.303 pp. 1990.
Cambridge University Press, Cambridge. back); $29.50 (paperback).
$69.50 (hard-
Marine animals could have invaded the land either directly or via a fresh water ancestor. The littorinacea snails have terrestrial forms that appear from their blood and urine
It is very helpful to have a summary volume on the form and activities of adrenergic neurons. The chapters deal with the life cycle of noradrenaline (NA); NA release; adrenoreceptors; NA synthesis and metabolism; regulation of receptors; regulation of synthesis; regulation of release; plasticity of NA neurons; peripheral NA neurons; central NA neurons; function of the locus ceruleus. The text is clearly written, well illustrated, and fully documented. A very useful book.
Book Reviews
and all the chapters hang together. Both theory and practical work on MAb is given. It deals with the immune response; hybridoma technology; factors affecting successful hybridoma production; selection of MAb-secreting hybridoma cell lines; large scale production of MAb h vitro; diversity in application of MAb and hybridoma technology (identification of viruses, antigenic variation in viruses, leukocyte markers, lymphocyte helper and suppressor factors, diagnosis and analysis of tumor antigens, identification of bacteria and parasites, identification of cell lines).
osmotic pressure and ionic composition to be derived from marine forms whilst the cyclophoridae terrestrial snails seem to have used the fresh water route. Similar evidence indicates that the woodlice came from a marine ancestor not a fresh water one. The book also discusses problems of terrestrial versus aquatic habitats; muddy and shore life; saltmarshes and mangrove swamps; terrestrial adaptations. It is very interesting to see the physiological evidence being used to interpret ecological adaptations. Neurobiology of Myrih e&&s-Edited 312 pp. 1990. Manchester University
by G. B. STEFANO. Press, Manchester.
Structures and Fuoctiomv of tbe Low AtUnity Fe ReceptorsEditor W. H. FRIDMAN.258 pp. 1990. S. Karger Basel. S.Fr
$75.
215 DM 257 $143.50.
Myrilus (the edible mussel) has been studied in particular for the properties of its catch muscle where the muscle can remain contracted at a specific length for hours with minimal energy expenditure. Myrilus is also useful for studying other physiological/pharmacological activities and these are discussed in the present volume. The chapters deal with; growth and environmental responsiveness; monoamine and opioid localization; neurotransmitters; CAMP; modulators; thermal acclimation during monoamine axonal transport; autoregulation; ageing.
Receptors for the Fc region of immunoglobulins mediate interactions between cells and immunoglobulins of different isotypes. The high affinity Fc receptors for IgE mediates degranulation of mast cells and basophils. The low affinity Fc receptors for IgG and IgE are expressed on lymphocytes, macrophages, polymorphonuclear cells and mast cells. They trigger killer cells to destroy Ig sensitized target cells; trigger eosinophils to produce. toxins against parasites; mediates phagocytosis of opsonised particles. This volume deals with the structure of Fc receptors for IgG; murine type Fc receptors; human FceRII; regulation of FceR2; eosinophil effector function; targeting and activation of cytotoxic lymphocytes; mononuclear cell cytotoxicity. It gets more like Starwars every day!
The Biology amI Medicine of Signal TrauaduetIon-Edited by Y. NISHIZUKA,M. ENDOand C. TANAKA.Advances in 2nd Messenger and Plwepboprotein Reaearcb. Vol. 24. 750 pp. 1990. Raven Press, New York. $99. This book contains the proceedings of a conference held in Kobe, Japan, October 1989. There are 90 papers. The topics include; receptors (adrenergic, ACh); DNA homology screening; ionic channels; G proteins; adenylate cyclase; PKC and CaMK; calcium entry and release; calmodulin; IP3, phospholipase C; tryrosine kinase; insulin receptor; receptor crosstalk, EDRF; calpain. All the popular topics are here.
Neurotrausmitters In Embryogenesis-G. A. BUZNIKOV. Translated from the Russian by AN~I-IONY BASTOW.526 pp. 1990. Harwood Academic Publishers, New York. $250; SAS price S150. Various transmitters such as acetylcholine, catecholamines, indolealkylamines and gangliosides have effects on marine invertebrate embryos even before the nervous system has developed. They can affect cell division and cleavage, intercellular reactions, protein synthesis, and cell differentiation. There are two additional chapters; one by J. M. Lauder on transmitters and morphogenesis, and the other by S. B. Kater and P. G. Haydon on transmitter regulation of neurite growth, cone motility and synaptogenesis. CardiovascuIar Physiology-W. R. MILNOR.501 pp. 1990. Oxford University Press, New York. $37.95.
This single author textbook is designed for medical students and also as a reference book for more advanced readers. There is a list of those sections necessary for the first year medical course. The chapters are; the circulatory system; normal state of the circulation; properties of cardiac cells; lhsentials of Medical Microbiology. 4th Edition.-By W. A. VOLK, D. C. BENJAMIN,R. J. KADNERand J. T. PARSONS. the heart as a pump; electrical activity of the heart; principles of hemodynamics; cardiovascular control system; 803 pp. 1990. J. B. Lippincott, Philadelphia. Paperback autonomic and peripheral control; regulation of vascular $37.50. smooth muscle; capillary and lymphatic systems; regional circulations; blood; methods of measurement. Each chapter The fourth edition of this interesting, informative and is followed by references to reviews and to research papers. readable textbook has had the chapters brought up to date; The text is clearly written and the book is a good supplement 150 new or revised illustrations; has more on AIDS, cancer to those who find the standard texts too brief, or the major and the molecular biology approach to diseases. The main handbooks too complicated. topics are immunology; bacterial physiology and genetics; bacteria and fungi; virology; medical parasitology. Each chapter also has references to journals and to other books. Noradrewrgic Neurons-By M. FILLENZ.238 pp. 1990 CamVery good value for money. bridge University Press, Cambridge. Wt.50 (hardback); $19.95 (paperback). Tbe Terrestrial Invasion; An Ecopbysiological Approach to the thighs of Land A&u&-By C. LITTLE.303 pp. 1990.
Cambridge University Press, Cambridge. back); $29.50 (paperback).
$69.50 (hard-
Marine animals could have invaded the land either directly or via a fresh water ancestor. The littorinacea snails have terrestrial forms that appear from their blood and urine
It is very helpful to have a summary volume on the form and activities of adrenergic neurons. The chapters deal with the life cycle of noradrenaline (NA); NA release; adrenoreceptors; NA synthesis and metabolism; regulation of receptors; regulation of synthesis; regulation of release; plasticity of NA neurons; peripheral NA neurons; central NA neurons; function of the locus ceruleus. The text is clearly written, well illustrated, and fully documented. A very useful book.