The chemical diagnosis of early pregnancy

:tIl~l

ovary

wa8

<-i-:&ally

and

tnhe dwr

noted uterim

WE the

These rotation

detrrlllinerl.

~~audally

and

projected pole.

nt

Suction of ova into the t)f the tuhc. is discusst~d.

Samuels, J. : Early 1937.

first

tuilles,

Diagnosis

studies of the ow=r

th

demonstrsted displacement of the ovary The ost,ium of the ovary on long axis. upper pole of thud ovary and snhsequently

set up by csilia and

of Pregnancy,

alao due to rhythmic*

Miit~vhw.

(*ontractions

nwtl. Wchuschr.

84: IX!::,

The writer presents a direct spectroscaol.lio method of diagnosing et~rl.~ Ixegnancy. tie employs an instrument, called a cycaloscope (syectroreduotometer) , which rletermines the reduction of oxyhemoglobin, which in nonpregnant individuals takes about. 145 seconds. Pregnancy is diagnosed when the cay&c variations which are observed He claims that the cycloscope will, in every in nonpregnant individuals are absent. case, diagnose :S pregnanczy seven or eight days at&r conception or twelve days b(+fore t,he time of the next menses. The

test

is rapid

and

simple

and

cun

be carried

out

by any

phyxieian. J.

Patterson, Jocelyn: 5”” “) 1937 .

The Chemical

Diagnosis

of Early

P.

Pregnancy,

GKFFNHILL 1*

Brit.

M.

. J-. 2:

A biochemical test for the diagnosis of early pregnancy is describetl which is hased upon bacterial splitting of oestriol glycuronide and the subsequent development of the oestriol color reaction with phenolsulphonie acid. Of 65 cases, in all rsoept one, the results coincided with those of the Friedman reaction. The advantages anil disadvantages of the test as compared with other biologic tests are discussed. F. I,. aDAIR AND 8. ,k. !?EAl’&.

Schneider, Bernhard, and Cohen, Armand: Nonspecificity of Gonadotropic of Pregnancy Urine Intradermally, J. A. M. A. 109: 115, 1937.

Factor

The results obtained wit,h antuit,rin-S, injected intradermally, in no way exhibit the reliability of this test as a means of diagnosing pregnancy or gynecologic disorders. One hundred eighteen tests were done on 95 females and 23 males. The observations made would indicate that II individuals were nonpregnant and 107 were pregnant. Aet,ually, however, there were only 21 pregnancies. GWVEB

Gill, A. Morton, and Hawkins, John: Test, Brit. M. J. 2: 1069, 1937.

The Ant&it&-in

S Intrmrmal

LIESE.

Pregw

The authors attempted to substantiate the farordble results reported by early investigators of the antuitrin-S intradermal pregnancy test. Male medical students, and pregnant and nonpregnant females were studied. The cutaneous reactions were read at one-half, one, and two hours. The results from antuitrin were so palpably inaccurate for the first 147 cases that the investigation was abandoned at that point. Thinking that perhaps the foreign protein rather than the specific hormonal content accounted for some of &e skin reitctions, an addSma 41 in&~&&s were tested with inactivated antuitrin-8. The results from this group were as f&&o~