The Plasma Fraction of Stored Packed Red Blood Cells Classically Activates Monocytes in Vitro

ASSOCIATION FOR ACADEMIC SURGERY AND SOCIETY OF UNIVERSITY SURGEONS—ABSTRACTS 63.9. Method for High Sensitivity KRAS Mutation Detection in Circulating Tumor Cells (CTCs). C. J. Tignanelli,1 R. J. Torphy,2 S. A. Soper,4,5 J. Yeh1,3,6,7; 1University Of North Carolina - Department Of Surgery, Chapel Hill, NC, USA; 2 University Of North Carolina - School Of Medicine, Chapel Hill, NC, USA; 3University Of North Carolina - Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA; 4 University Of North Carolina - Department Of Chemistry, Chapel Hill, NC, USA; 5UNC-NCSU - Department Of Biomedical Engineering, Chapel Hill, NC, USA; 6University Of North Carolina - Department Of Pharmacology, Chapel Hill, NC, USA; 7University Of North Carolina - Department Of Surgical Oncology, Chapel Hill, NC, USA

63.10. Role of DNA-PKcs, Ku80 and Bax in Radioresistance of HT-29 Cells and Xenografts. X. Gao,1 J. Meyer,1 S. Huerta1,3; 1University Of Texas Southwestern Medical Center - Surgery, Dallas, TX, USA; 3VA North Texas Health Care System - Surgery, Dallas, TX, USA

63.11. Assessing Tumor Angiogenesis with Computed Tomography and a Novel Nanoparticle Contrast Agent in an In Vivo Model of Neuroblastoma. A. Lakoma,1 K. B. Ghaghada,2 C. Adhikari,3 C. C. Kaffes,2 Y. Rojas,1 J. M. Shohet,3 A. Annapragada,2 E. S. Kim1; 1Baylor College Of Medicine - Division Of Pediatric Surgery, Michael E DeBakey Department Of Surgery, Houston, TX, USA; 2 Baylor College Of Medicine - Department Of Radiology, Houston, TX, USA; 3Baylor College Of Medicine Department Of Pediatrics, Houston, TX, USA

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D. R. Vera2; 1University Of California - San Diego Department Of General Surgery, San Diego, CA, USA; 2 University Of California - San Diego - Department Of Radiology, San Diego, CA, USA

63.15. GSK-3 Is Frequently Activated In Pancreatic Cancer Through c-Myc Regulation And Is A Novel Target For Therapy. R. Bold,1 S. Virudachalam,1 R. J. Bold1; 1 University Of California - Davis - Surgical Oncology, Sacramento, CA, USA

63.16. Effect of Sphingosine-1-Phosphate Signaling Disruption in a Murine Synergenic Metastatic Breast Cancer Model. K. P. Terracina,1 B. J. Adams,1 O. M. Rashid,1 A. Yamada,1,2 M. Nagahashi,1,2 S. Ramachandran,1,2 S. 1 S. Spiegel,2 K. Takabe1,2; Virginia Milstien,2 Commonwealth University - Department Of Surgery, Richmond, VA, USA; 2Virginia Commonwealth University Department Of Biochemistry And Molecular Biology, Richmond, VA, USA

63.17. Inpatient Survival after Gastrectomy for Gastric Cancer in the 21st Century: Are We Making Progress? H. Wang,1 T. M. Pawlik,1 M. D. Duncan,1 X. Hui,1 S. Selvarajah,1 J. K. Canner,1 A. H. Haider,1 N. Ahuja,1 E. B. Schneider1; 1Johns Hopkins University School Of Medicine - Surgery, Baltimore, MD, USA

63.12. Telo2 Upregulation is Associated with Chemoradioresistant Rectal Cancer. G. A. Gantt,1 I. Kopyeva,1 Y. Chen,2 K. DeJulius,3 A. Jarrar,1 A. G. Mace,1 J. BarnholtzSloan,2 M. F. Kalady1,3; 1Cleveland Clinic - Digestive Disease Institute, Colon And Rectal Surgery, Cleveland, OH, USA; 2Case Western Reserve University School Of Medicine - Comprehensive Cancer Center, Cleveland, OH, USA; 3 Cleveland Clinic - Lerner Research Institute, Stem Cell Biology, Cleveland, OH, USA

63.18. Connective Tissue Growth Factor (CTGF/CCN2) is a Direct Transcriptional Target of SOX2 and Regulator of Integrin Alpha 5, Bone Morphogenetic Protein 7, and Collagen I Alpha 1 Expression in Squamous Cell Lung Cancer. M. K. Mallipeddi,1 J. M. Hanna,1 C. R. Futtner,1 M. W. Onaitis1; 1Duke University Medical Center - Surgery, Durham, NC, USA

63.13. The Plasma Fraction of Stored Packed Red Blood Cells Classically Activates Monocytes in Vitro. J. A. Yi,1 K. Lo,1 C. C. Silliman,1 B. H. Edil,1 R. D. Schulick,1 K. C. El Kasmi,1 C. C. Barnett1,2; 1University Of Colorado Denver, Aurora, CO, USA; 2Denver Health Medical Center, Denver, CO, USA

63.19. An Evaluation of PI3K-mTOR Mediated Cell Growth Suppression by Baicalein and Quercetin in Cancer Cells. D. Luyimbazi,1 Y. Wang,1 J. Yan,1 Q. Xing,1 J. Yim1; 1 City Of Hope National Medical Center - Surgical Oncology, Duarte, CA, USA

63.14. Dendritic Cell Receptor-Specific Binding Properties of [99mTc] -Cy7-Tilmanocept and its use as a Multireporter Probe in Tumor Margin Analysis. A. Hosseini,1 J. L. Baker,1 C. A. Tokin,1 Z. Qin,2 A. M. Wallace,1

63.20. Exogenous Schlafen 12 Expression In The Lncap Prostate Cancer Cell Line Modulates Cell Differentiation. P. L. Kovalenko,1 M. D. Basson1; 1Michigan State University Department Of Surgery, Lansing, MI, USA