V International symposium on bioluminescence and chemiluminescence

Journal oflmmunologicalMethods, 103 (1987) 158 159

158

Elsevier JIM04570 Announcements

V International Symposium on Bioluminescence and Chemiluminescence F l o r e n c e - B o l o g n a , Italy, S e p t e m b e r 2 5 - 2 9 , 1988

The symposium in Florence will cover the fundamental aspects and the most recent applications of bioluminescence and chemiluminescence in clinical sciences, biotechnology, genetics, microbiology, phagocytosis, immunoassay, environmental monitoring. The symposium will consist of invited lectures, short communications, poster sessions and workshops. 'Alma Mater Studiorum S~ecularia Nona': the

meeting will include a special symposium on September, 27, 1988 in Bologna as part of the celebration to mark the foundation of the University of Bologna in the l l t h century. Further information is available from: Professor Mario Pazzagli, Endocrinology Unit, Uniuersity

of Florence, Viale Morgagni, 85, 50134 Florence, Italy. Deadline for abstracts: March, 15, 1988.

0022-1759/87/$03.50 © 1987 Elsevier Science Publishers B.V. (Biomedical Division)

159 JIM04571

WHO / IUIS programme for the standardization of immunological reagents - availability of mouse monoclonal antibodies (McAb) to human IgG subclasses Following a W H O / I U I S Collaborative Study: Evaluation of McAb having specificity for human IgG subclasses (Jefferis et al., Immunol. Lett., 10, 223-252 (1985)) sixteen (16) McAb have been established as useful specificity standards as follows: Specificity

Clone designation

Study code

Fc Fc Fab Fab

HP6017 8a4 HP6045 TM15

HP6017 HP6064 HP6045 HP6063

Anti-IgG1, Fc Anti-IgG1, Fc Anti-IgG1, Fc

NL16 2B6 8c/6-39

HP6012 HP6069 HP6091

HP6002 GOM1 HP6014

HP6002 HP6008 HP6014

HP6050

HP6050

RJ4 186

HP6011 HP6101

TM14 H86-2.4 HP6016

HP6027 HP6080 HP6016

IgG (total) Anti-IgG, Anti-IgG, Anti-IgG, Anti-IgG,

IgG1

IgG2 Anti-IgG2, Fc Anti-IgG2, Fc Anti-IgG2, Fab

IgG3 Anti-IgG3 (hinge region)

IgG4 Anti-IgG4, Fc Anti-IgG4, Fc

A llotypes Glm(f) G3m(u) nG4m(b)

For details of the evaluation and limitations to use of these McAb see the above reference (Jefferis et al.). Vials containing reference amounts of these McAb (0.2 ml of freeze-dried ascitic fluid) are available, on a limited basis (one vial per year to individual laboratories, five vials per year to national regulatory authorities and bona-fida commercial reagent manufacturers), on application to: Chief, WHO Collaborating Centre for Human Immunoglobulin Subclasses, Building 1, Room 1354 DO3, Centers for Disease Control, Atlanta, GA 30333, U.S.A. F o r I U I S H u m a n Ig S u b c o m m i t t e e , R. JEFFERIS, C. REIMER, F. SKVARIL AND G. DE LANGE.