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5176911 Pharmaceutical compositions comprising selected lactobacillus strains
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PATENT ABSTRACTS
5175255 METHODS FOR PURIFICATION OF PLATELET-DERIVED GROWTH FACTOR
host mouse. The gene encodes the interferon of a different animal species and therefore its expression product is less toxic to the host at an embryonic, fetal, neonatal or junvenile stage of development. Preferably, the human beta interferon gene is introduced into the cells of a mouse.
Arlen Thomason, Margery A Nicolson assigned to Amgen Inc Monoclonal antibodies specific for epitopes found on the B chain of PDGF (including v-sis, c-sis and platelet-derived forms) may be bound to columns and used for purification of rPDGF B. A solution containing a polypeptide possessing at least part of the structural conformation of rPDGF B is passed over such a column and the rPDGF B is bound to the antibody. The rPDGF B may then be eluted from the column to yield rPDGF B of greater than 95~ purity as determined by SDS-PAGE.
5175257 RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE
5176911 PHARMACEUTICAL COMPOSITIONS COMPRISING SELECTED LACTOBACILLUS STRAINS Silvana Tosi, Giancarla Dondi, Vittorio Bottazzi, Franco Dellaglio, Lorenzo Morelli, Novara, Italy assigned to Universita Cattolica del Sacro Cuore; Dr A Tosi Farmaceutici S r 1 Topical pharmaceutical compositions, suited for the use in gynecology and urology, comprise as active principles selected Lactobacillus strains isolated from vaginal or urologic habitat of asymptomatic patients.
5177000 Sudhaka Kasina, Ananthachari Srinivasan, John M Reno, Linda M Gustavson, Jeffrey N Fitzner, David Jones assigned to NeoRx Corporation Chelating compounds of specified N2S2 N3S derived structure are useful for radiolabeling targeting molecules such as antibodies. Cleavable ester orthioester linkers connect the radionuclide metal chelates to the antibodies. The radiolabeled antibodies have improved biodistribution properties, including reduced localization within the intestines and kidneys.
MONOCLONAL ANTIBODIES SELECTIVE FOR PROSTATE CANCER AND DIAGNOSTIC IMMUNOASSAY FOR PROSTATE CANCER Michel Bazinet, Richard Cote, Lloyd J Old assigned to Sloan Kettering Institute for Cancer Research Four monoclonal antibodies are found which selectively identify prostate cancer. These monoclonals are therefore useful in diagnosis and differential diagnosis of prostate cancer.
5175385 VIRUS-RESISTANT TRANSGENIC MICE Thomas E Wagner, Xiao-Zhu Chen assigned to Ohio University/Edison Animal Biotechnolgy Center A transgenic mouse with enhanced viral resistance transmissible to its offspring is prepared by introduction of a gene encoding a human interferon having antiviral activity into a
5177014 MONOCLONAL ANTIBODIES TO FELINE-T-LYMPHOTROPIC LENTIVIRUS Thomas P O'Connor, Quentin Tonelli, Philip Andersen assigned to Idexx Laboratories Inc Monoclonal antibodies specific for an epitope of an FIV-encoded antigen.
PATENT ABSTRACTS
5175255 METHODS FOR PURIFICATION OF PLATELET-DERIVED GROWTH FACTOR
host mouse. The gene encodes the interferon of a different animal species and therefore its expression product is less toxic to the host at an embryonic, fetal, neonatal or junvenile stage of development. Preferably, the human beta interferon gene is introduced into the cells of a mouse.
Arlen Thomason, Margery A Nicolson assigned to Amgen Inc Monoclonal antibodies specific for epitopes found on the B chain of PDGF (including v-sis, c-sis and platelet-derived forms) may be bound to columns and used for purification of rPDGF B. A solution containing a polypeptide possessing at least part of the structural conformation of rPDGF B is passed over such a column and the rPDGF B is bound to the antibody. The rPDGF B may then be eluted from the column to yield rPDGF B of greater than 95~ purity as determined by SDS-PAGE.
5175257 RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE
5176911 PHARMACEUTICAL COMPOSITIONS COMPRISING SELECTED LACTOBACILLUS STRAINS Silvana Tosi, Giancarla Dondi, Vittorio Bottazzi, Franco Dellaglio, Lorenzo Morelli, Novara, Italy assigned to Universita Cattolica del Sacro Cuore; Dr A Tosi Farmaceutici S r 1 Topical pharmaceutical compositions, suited for the use in gynecology and urology, comprise as active principles selected Lactobacillus strains isolated from vaginal or urologic habitat of asymptomatic patients.
5177000 Sudhaka Kasina, Ananthachari Srinivasan, John M Reno, Linda M Gustavson, Jeffrey N Fitzner, David Jones assigned to NeoRx Corporation Chelating compounds of specified N2S2 N3S derived structure are useful for radiolabeling targeting molecules such as antibodies. Cleavable ester orthioester linkers connect the radionuclide metal chelates to the antibodies. The radiolabeled antibodies have improved biodistribution properties, including reduced localization within the intestines and kidneys.
MONOCLONAL ANTIBODIES SELECTIVE FOR PROSTATE CANCER AND DIAGNOSTIC IMMUNOASSAY FOR PROSTATE CANCER Michel Bazinet, Richard Cote, Lloyd J Old assigned to Sloan Kettering Institute for Cancer Research Four monoclonal antibodies are found which selectively identify prostate cancer. These monoclonals are therefore useful in diagnosis and differential diagnosis of prostate cancer.
5175385 VIRUS-RESISTANT TRANSGENIC MICE Thomas E Wagner, Xiao-Zhu Chen assigned to Ohio University/Edison Animal Biotechnolgy Center A transgenic mouse with enhanced viral resistance transmissible to its offspring is prepared by introduction of a gene encoding a human interferon having antiviral activity into a
5177014 MONOCLONAL ANTIBODIES TO FELINE-T-LYMPHOTROPIC LENTIVIRUS Thomas P O'Connor, Quentin Tonelli, Philip Andersen assigned to Idexx Laboratories Inc Monoclonal antibodies specific for an epitope of an FIV-encoded antigen.