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5177215 Heterocyclic compounds and pharmaceutical use thereof
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New Patents
acceptable acid addition salts thereof are useful as pharmaceuticals, e.g. in the treatment of asthma.
5177096 SUBSTITUTED 5-((TETRAZOLYL) ALKENYL)IMIDAZOLES AND PHARMACEUTICAL METHODS OF USE THEREOF Richard M Keenan, Joseph Weinstock assigned to SmithKline Beecham Corporation Angiotensin II receptor antagonists having the formula: See Patent for Chemical Structure which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals.
5177215 HETEROCYCLIC C O M P O U N D S AND PHARMACEUTICAL USE THEREOF Kiyoshi Murase, Toshiyasu Mase, Hiromu Hara, Kenichi Tomioka, Saitama, Japan assigned to Yamanouchi Pharmaceutical Co Ltd Novel heterocyclic compounds shown by the general formula See Patent for Chemical Structure or the pharmaceutically acceptable salts thereof useful as medicament in particular as antagonist of slow reacting substance of anaphylaxis (SRS-A).
5178850 CRYSTALLINE SUGAR ALCOHOL CONTAINING UNIFORMLY DISPERSED LIQUID PHARMACEUTICAL C O M P O U N D James W DuRoss assigned to ICI Americas Inc
5177111 ALKYLAMINO- AND ALKYLAMINO ALKYL DIARYLKETONES AND PHARMACEUTICAL COMPOSITIONS THEREOF R Richard L Hamer, Brian Freed, Richard Allen assigned to Hoechst-Roussel Pharmaceuticals Inc This invention relates to alkylamino and alkyl amino alkyl diarylketones of the formula See Patent for Chemical Structure where Ar is aryl of the formula See Patent for Chemical Structure where V is hydrogen, halogen, loweralkyl, loweralkoxy, CF3, NO2 and u is an integer of 1 to 3; X and Y are independently CH2--CF2- or CHF-; Z and W are independently -CH2-, -O-, CHOH-, or -CHF-; m, n, p, q and t are integers which are independently 0 or 1, R1 is H or loweralkyl; R2 and R3 are loweralkyl; and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as analgesic agents and as agents for alleviating various memory dysfunctions, characterized by a decreased cholinergic function, such as Alzheimer's disease.
A pharmaceutical composition comprising a crystalline sugar alcohol derived from at least one mono- or polysaccharide having at least one liquid pharmaceutically active compound uniformly dispersed within its crystal matrix is disclosed. Also disclosed is a method of producing such a uniformly dispersed pharmaceutical composition by the controlled crystallization of the molten sugar alcohol having the pharmaceutically active material dispersed therein.
5178852 COSMETIC AND PHARMACEUTICAL COMPOSITIONS CONTAINING LIPOPHILIC DERIVATIVES OF BENZYLIDENECAMPHOR AND NEW LIPOPHILIC DERIVATIVES OF BENZYLIDENECAMPHOR Serge Forestier, Alain Lagrange, Gerard Lang, Andre Deflandre, Bernadette Luppi, Claye Souilly, France assigned to L'Oreal The invention relates to cosmetic and pharmaceutical compositions containing the derivatives of benzylidenvcamphor of formula: See Patent
New Patents
acceptable acid addition salts thereof are useful as pharmaceuticals, e.g. in the treatment of asthma.
5177096 SUBSTITUTED 5-((TETRAZOLYL) ALKENYL)IMIDAZOLES AND PHARMACEUTICAL METHODS OF USE THEREOF Richard M Keenan, Joseph Weinstock assigned to SmithKline Beecham Corporation Angiotensin II receptor antagonists having the formula: See Patent for Chemical Structure which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals.
5177215 HETEROCYCLIC C O M P O U N D S AND PHARMACEUTICAL USE THEREOF Kiyoshi Murase, Toshiyasu Mase, Hiromu Hara, Kenichi Tomioka, Saitama, Japan assigned to Yamanouchi Pharmaceutical Co Ltd Novel heterocyclic compounds shown by the general formula See Patent for Chemical Structure or the pharmaceutically acceptable salts thereof useful as medicament in particular as antagonist of slow reacting substance of anaphylaxis (SRS-A).
5178850 CRYSTALLINE SUGAR ALCOHOL CONTAINING UNIFORMLY DISPERSED LIQUID PHARMACEUTICAL C O M P O U N D James W DuRoss assigned to ICI Americas Inc
5177111 ALKYLAMINO- AND ALKYLAMINO ALKYL DIARYLKETONES AND PHARMACEUTICAL COMPOSITIONS THEREOF R Richard L Hamer, Brian Freed, Richard Allen assigned to Hoechst-Roussel Pharmaceuticals Inc This invention relates to alkylamino and alkyl amino alkyl diarylketones of the formula See Patent for Chemical Structure where Ar is aryl of the formula See Patent for Chemical Structure where V is hydrogen, halogen, loweralkyl, loweralkoxy, CF3, NO2 and u is an integer of 1 to 3; X and Y are independently CH2--CF2- or CHF-; Z and W are independently -CH2-, -O-, CHOH-, or -CHF-; m, n, p, q and t are integers which are independently 0 or 1, R1 is H or loweralkyl; R2 and R3 are loweralkyl; and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as analgesic agents and as agents for alleviating various memory dysfunctions, characterized by a decreased cholinergic function, such as Alzheimer's disease.
A pharmaceutical composition comprising a crystalline sugar alcohol derived from at least one mono- or polysaccharide having at least one liquid pharmaceutically active compound uniformly dispersed within its crystal matrix is disclosed. Also disclosed is a method of producing such a uniformly dispersed pharmaceutical composition by the controlled crystallization of the molten sugar alcohol having the pharmaceutically active material dispersed therein.
5178852 COSMETIC AND PHARMACEUTICAL COMPOSITIONS CONTAINING LIPOPHILIC DERIVATIVES OF BENZYLIDENECAMPHOR AND NEW LIPOPHILIC DERIVATIVES OF BENZYLIDENECAMPHOR Serge Forestier, Alain Lagrange, Gerard Lang, Andre Deflandre, Bernadette Luppi, Claye Souilly, France assigned to L'Oreal The invention relates to cosmetic and pharmaceutical compositions containing the derivatives of benzylidenvcamphor of formula: See Patent