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Announcement (ii)
Journal of the Autonomic Nervous System, 8 (1983) 399-400 Elsevier
399
Announcement (II) Availability of NASA support for biomedical research Objective
The purpose of NASA's Biomedical Research Program is to investigate, in ground-based facilities, the major physiological and psychological problems encountered by man in space, and to develop solutions. Of the eight categories of biomedical problems in the Program, cardiovascular deconditioning and space motion sickness are two of the most pressing with respect to the short-duration Space Shuttle missions. Identification and characterization of the biologic mechanisms of cardiovascular deconditioning and space motion sickness will lead to practical methods of prevention or control of these debilitating syndromes. The current NASA Program supporting these two research areas and opportunities for future investigations are reviewed in two recent reports * Approaches
Investigations to define the nature and elaborate the mechanisms of cardiovascular deconditioning and space motion sickness are carried out in ground-based facilities. Such research may or may not benefit from the use of analogues of the space flight environment such as bed rest, water immersion, or special motion and acceleration devices. Desired investigations may range from very basic research to applied test and analysis, and may employ experimental animals or human subjects, and in vitro or modeling techniques. Ground-based studies lead to identification and design of experiments to be carried out in space. Improvement in methodology, instrumentation, and equipment is an essential part of the technology development needed for achieving the solutions to problems of cardiovascular deconditioning and space motion sickness.
* The information in this announcement is provided by the Life Sciences Research Office, FASEB, and is based on recently completed reviewsof NASA's research programs. The reports, 'Research Opportunities in Cardiovascular Deconditioning' and 'Research Opportunities in Space Motion Sickness', are available from the Life Sciences Research Office, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, U.S.A. 0165-1838/83/$03.00 © 1983 Elsevier Science Publishers B.V.
400 N A S A research support
If you have an interest in any of the following topics as they may relate to solution of the problems of cardiovascular deconditioning and space motion sickness, then you may qualify for NASA research support: Cardiovascular deconditioning
(1) Pathogenesis (2) Countermeasures (3) Improved methodology (4) Effects of simulated zero-G on: cardiovascular regulatory control; hemodynamics and blood flow redistribution; vascular capacitance; cardiovascular system receptor mechanisms; myocardial metabolism and integrity; interactions between the cardiovascular and other organ systems. Space motion sickness
(1) (2) (3) (4) (5) (6) (7) (8) (9) (10)
Definition of the adequate stimulus Pathogenesis Neurological, biochemical, and neuropharmacological aspects Vomiting mechanisms Vestibular and associated sensory physiology Brainstem, cerebellar, and cortical influences Biological individuality of susceptibility and tolerance Habituation to motion sickness stimuli Improved methodology Measures and devices for prevention and control.
The NASA Biomedical Research Program is conducted intramurally by the NASA Research Centers and by means of extramural grants and contracts. Qualified scientists interested in learning more about the Program and in submitting research proposals should write to: Paul C. Rambaut, Sc.D., Manager Biomedical Research Program/EBT-3, Life Sciences Division NASA Headquarters, Washington, DC 20546, U.S.A.
399
Announcement (II) Availability of NASA support for biomedical research Objective
The purpose of NASA's Biomedical Research Program is to investigate, in ground-based facilities, the major physiological and psychological problems encountered by man in space, and to develop solutions. Of the eight categories of biomedical problems in the Program, cardiovascular deconditioning and space motion sickness are two of the most pressing with respect to the short-duration Space Shuttle missions. Identification and characterization of the biologic mechanisms of cardiovascular deconditioning and space motion sickness will lead to practical methods of prevention or control of these debilitating syndromes. The current NASA Program supporting these two research areas and opportunities for future investigations are reviewed in two recent reports * Approaches
Investigations to define the nature and elaborate the mechanisms of cardiovascular deconditioning and space motion sickness are carried out in ground-based facilities. Such research may or may not benefit from the use of analogues of the space flight environment such as bed rest, water immersion, or special motion and acceleration devices. Desired investigations may range from very basic research to applied test and analysis, and may employ experimental animals or human subjects, and in vitro or modeling techniques. Ground-based studies lead to identification and design of experiments to be carried out in space. Improvement in methodology, instrumentation, and equipment is an essential part of the technology development needed for achieving the solutions to problems of cardiovascular deconditioning and space motion sickness.
* The information in this announcement is provided by the Life Sciences Research Office, FASEB, and is based on recently completed reviewsof NASA's research programs. The reports, 'Research Opportunities in Cardiovascular Deconditioning' and 'Research Opportunities in Space Motion Sickness', are available from the Life Sciences Research Office, FASEB, 9650 Rockville Pike, Bethesda, MD 20814, U.S.A. 0165-1838/83/$03.00 © 1983 Elsevier Science Publishers B.V.
400 N A S A research support
If you have an interest in any of the following topics as they may relate to solution of the problems of cardiovascular deconditioning and space motion sickness, then you may qualify for NASA research support: Cardiovascular deconditioning
(1) Pathogenesis (2) Countermeasures (3) Improved methodology (4) Effects of simulated zero-G on: cardiovascular regulatory control; hemodynamics and blood flow redistribution; vascular capacitance; cardiovascular system receptor mechanisms; myocardial metabolism and integrity; interactions between the cardiovascular and other organ systems. Space motion sickness
(1) (2) (3) (4) (5) (6) (7) (8) (9) (10)
Definition of the adequate stimulus Pathogenesis Neurological, biochemical, and neuropharmacological aspects Vomiting mechanisms Vestibular and associated sensory physiology Brainstem, cerebellar, and cortical influences Biological individuality of susceptibility and tolerance Habituation to motion sickness stimuli Improved methodology Measures and devices for prevention and control.
The NASA Biomedical Research Program is conducted intramurally by the NASA Research Centers and by means of extramural grants and contracts. Qualified scientists interested in learning more about the Program and in submitting research proposals should write to: Paul C. Rambaut, Sc.D., Manager Biomedical Research Program/EBT-3, Life Sciences Division NASA Headquarters, Washington, DC 20546, U.S.A.