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Cytokine gene polymorphism frequencies in a population from Prague, Czech Republic
924
HLA alleles B*6701 B*73 B*7301 B*78 B*7801 B*7802 B*7803 B*81 B*8101 B*82 B*8201
Frequency (%) Gene frequency 0 0 0 0 0 0 2.4 0.012 2.4 0.012 0 0 0 0 2.4 0.012 2.4 0.012 0 0 0 0
HLA haplotypes Frequency (%) A*0101-B*0801 A*0101-B*3501 A*0101-B*5301 A*0201-B*4501 A*0201-B*5101 A*0201-B*5802 A*0301-B*0702 A*0301-B*4901 A*2301-B*0702 A*2301-B*3501 A*2402-B*3502 A*2601-B*4901 A*2902-B*4001 A*3303-B*5301 A*6802-B*1402 A*74-B*5101
2.4 2.4 2.4 3.6 2.4 2.4 2.4 2.4 2.4 3.6 2.4 2.4 2.4 4.8 2.4 2.4
KIR alleles
Frequency (%)
2DL4 2DL4*00101 2DL4*00102 2DL4*00201 2DL4*00202 2DL4*003 2DL4*004 2DL4*005 2DL4*006 2DL4*007
100 0 64.3 35.7 19.1 0 0 45.2 9.5 0
Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
Cytokine Gene Polymorphism Frequencies in a Population from Prague, Czech Republic A. Slavcev* and I. Striz Department of Immunogenetics, IKEM, Videnska 1958/9, Prague, Czech Republic E-mail: *[email protected] This population from Prague, Czech Republic, Latitude 50N Longitude 14E consisted of 103 Caucasian individuals. The individuals were drawn from an urban environment and cytokine polymorphisms were determined using sequence specific primers. Human Immunology 65, 924 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. Cytokine gene
Frequency (%)
IL-1alpha/-889 CC IL-1alpha/-889 CT IL-1alpha/-889 TT IL-1beta/3962 CC IL-1beta/3962 CT IL-1beta/3962 TT IL-2/-330 GG IL-2/-330 GT IL-2/-330 TT IL-2/166 GG IL-2/166 GT IL-2/166 TT IL-4/-590 CC IL-4/-590 CT IL-4/-590 TT IL-6/-174 CC IL-6/-174 CG IL-6/-174 GG IL-10/-592 AA IL-10/-592 AC IL-10/-592 CC IL-10/-819 CC IL-10/-819 CT IL-10/-819 TT IL-10/-1082 AA IL-10/-1082 AG IL-10/-1082 GG TNFalpha/-238 AA TNFalpha/-238 AG TNFalpha/-238 GG TNFalpha/-308 AA TNFalpha/-308 AG TNFalpha/-308 GG
64.7 22.5 12.7 48 36.3 15.7 10.9 44.6 44.6 47.5 41.6 10.9 75.5 18.6 4.9 19.4 51.5 29.1 5.8 46.6 47.6 46.6 48.5 4.9 20.4 68.9 10.7 1 14.9 84.2 3 27.8 69.3
0198-8859/04/$–see front matter
HLA alleles B*6701 B*73 B*7301 B*78 B*7801 B*7802 B*7803 B*81 B*8101 B*82 B*8201
Frequency (%) Gene frequency 0 0 0 0 0 0 2.4 0.012 2.4 0.012 0 0 0 0 2.4 0.012 2.4 0.012 0 0 0 0
HLA haplotypes Frequency (%) A*0101-B*0801 A*0101-B*3501 A*0101-B*5301 A*0201-B*4501 A*0201-B*5101 A*0201-B*5802 A*0301-B*0702 A*0301-B*4901 A*2301-B*0702 A*2301-B*3501 A*2402-B*3502 A*2601-B*4901 A*2902-B*4001 A*3303-B*5301 A*6802-B*1402 A*74-B*5101
2.4 2.4 2.4 3.6 2.4 2.4 2.4 2.4 2.4 3.6 2.4 2.4 2.4 4.8 2.4 2.4
KIR alleles
Frequency (%)
2DL4 2DL4*00101 2DL4*00102 2DL4*00201 2DL4*00202 2DL4*003 2DL4*004 2DL4*005 2DL4*006 2DL4*007
100 0 64.3 35.7 19.1 0 0 45.2 9.5 0
Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
Cytokine Gene Polymorphism Frequencies in a Population from Prague, Czech Republic A. Slavcev* and I. Striz Department of Immunogenetics, IKEM, Videnska 1958/9, Prague, Czech Republic E-mail: *[email protected] This population from Prague, Czech Republic, Latitude 50N Longitude 14E consisted of 103 Caucasian individuals. The individuals were drawn from an urban environment and cytokine polymorphisms were determined using sequence specific primers. Human Immunology 65, 924 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. Cytokine gene
Frequency (%)
IL-1alpha/-889 CC IL-1alpha/-889 CT IL-1alpha/-889 TT IL-1beta/3962 CC IL-1beta/3962 CT IL-1beta/3962 TT IL-2/-330 GG IL-2/-330 GT IL-2/-330 TT IL-2/166 GG IL-2/166 GT IL-2/166 TT IL-4/-590 CC IL-4/-590 CT IL-4/-590 TT IL-6/-174 CC IL-6/-174 CG IL-6/-174 GG IL-10/-592 AA IL-10/-592 AC IL-10/-592 CC IL-10/-819 CC IL-10/-819 CT IL-10/-819 TT IL-10/-1082 AA IL-10/-1082 AG IL-10/-1082 GG TNFalpha/-238 AA TNFalpha/-238 AG TNFalpha/-238 GG TNFalpha/-308 AA TNFalpha/-308 AG TNFalpha/-308 GG
64.7 22.5 12.7 48 36.3 15.7 10.9 44.6 44.6 47.5 41.6 10.9 75.5 18.6 4.9 19.4 51.5 29.1 5.8 46.6 47.6 46.6 48.5 4.9 20.4 68.9 10.7 1 14.9 84.2 3 27.8 69.3
0198-8859/04/$–see front matter