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Issues and reviews in teratology (Vol. 2)
176
Reviews and abstracts
Am. J, Orthod. Februa~' 1986
which will influence healthcare policies. These decisions should not be made only by the specialists. This book should also be useful for those in health and related fields who received their training before much of our present knowledge about human genetics was obtained. Carol Jones
issues and Reviews in Teratology (Vol. 2) Harold Kalter (editor)
crose-maltose deficiency, of diet-fiber relationships, and of skeletal problems in patients receiving total parenteral nutrition. Other timely reviews cover problems of measurement of body protein turnover, the vitamin A-cancer story, metabolic aspects of zinc ligands, antiallergenic properties of ascorbic acid, and biochemistry of methionine metabolism. Finally, there is a detailed review of nutritional and physiological changes accompanying the germ-free state in experimental animals.
New York, 1984, Plenum, 516 pages. Price $69.50 (From American Sdentist 73: 390, 1985.)
Both the experimental and the human aspects of teratology are presented in this comprehensive text by a stellar group of internationally recognized scientists and clinicians. Three extensive reviews of birth-defect monitoring and epidemiology are included. Topics discussed range from statistical and identification problems to the congenital defects of domestic and feral animals. A complete review o'f the scientifiC literature concerning transplacental exposure to diethylstilbestera!, radiation, and industrial chemicals is likely to be a useful resource for both the experimental scientist and the practitioner. This text will also be useful to students and regulators, because it combines basic information concerning the causes and mechanisms of birth defects with a practical catalog of many causes of chemically induced birth defects. A scholarly review of hormones, growth factors, and their receptors in normal and abnormal prenatal development complements other chapters discussing morphogenesis, anthropomorphization, and human risk assessment. This book should be a valuable resource for those concerned with experimental teratology and risk assessment and those requiring general information about the causes of birth defects. The treatment of these issues is sophisticated, succinct, and logical. Raymond D. Harbison
Advances in Nutritional Research (Voh 6) Harold H. Draper (editor) New York, 1984, Plenum, 355 pages. Price $49.50 (From American Scientist 73: 392, 1985.)
The discussions included in this annual volume will be Of particular interest to clinical and experimental nutritionists and biochemists seeking well-reasoned assessments of the status of selected pertinent nutritional problems. Consideration is given to current clinical implications of the selenium-related Keshan disease, of su-
Richard M. Forbes
Research abstracts What is a Skeletal Open Bite? R. M. Bryant, A. Jacobson, and P. L. Sadowsky University of Alabama School of Dentistry, Tuscaloosa, 1985
Skeletal open bite pattern has become relatively well-accepted terminology referring to a specific set of morphologic facial skeletal characteristics. There are, however, those persons who exhibit many of these characteristics yet have a normal or deep vertical overbite. This investigation was undertaken to compare cephalometrically a group of subjects exhibiting hyperdivergent skeletal patterns and open bites with a group exhibiting hyperdivergent skeletal patterns and non-open bites. A sample of 60 patients was chosen, all of whom exhibited a mandibular plane angle of 36.5 ° or greater. Of these 60 patients, 34 exhibited open bites and 26 had normal to deep bites. A series of 22 cephalometric measurements were taken from the pretreatment cephalometric radiogram of each subject. In addition, the Jacobson template analysis was performed for each cephalometric radiogram. The results revealed the following differences: (1) the open bites had increased lower face height, (2) the palatal plane relative to sella nasion was less steeply inclined in the open bites, (3) the maxillary and mandibular incisors were more proclined in the open bites, (4) the anterior cranial base (S-N) inclination relative to the soft-tissue profile tended to be steeper in the non-open bites. The nonopen bites on average exhibited less divergency between the palatal and mandibular planes and more dentoalveolar compensation than the open bite group. These findings suggest that the mandibular plane to sella nasion angle is not always an accurate indicator of facial divergency.
Reviews and abstracts
Am. J, Orthod. Februa~' 1986
which will influence healthcare policies. These decisions should not be made only by the specialists. This book should also be useful for those in health and related fields who received their training before much of our present knowledge about human genetics was obtained. Carol Jones
issues and Reviews in Teratology (Vol. 2) Harold Kalter (editor)
crose-maltose deficiency, of diet-fiber relationships, and of skeletal problems in patients receiving total parenteral nutrition. Other timely reviews cover problems of measurement of body protein turnover, the vitamin A-cancer story, metabolic aspects of zinc ligands, antiallergenic properties of ascorbic acid, and biochemistry of methionine metabolism. Finally, there is a detailed review of nutritional and physiological changes accompanying the germ-free state in experimental animals.
New York, 1984, Plenum, 516 pages. Price $69.50 (From American Sdentist 73: 390, 1985.)
Both the experimental and the human aspects of teratology are presented in this comprehensive text by a stellar group of internationally recognized scientists and clinicians. Three extensive reviews of birth-defect monitoring and epidemiology are included. Topics discussed range from statistical and identification problems to the congenital defects of domestic and feral animals. A complete review o'f the scientifiC literature concerning transplacental exposure to diethylstilbestera!, radiation, and industrial chemicals is likely to be a useful resource for both the experimental scientist and the practitioner. This text will also be useful to students and regulators, because it combines basic information concerning the causes and mechanisms of birth defects with a practical catalog of many causes of chemically induced birth defects. A scholarly review of hormones, growth factors, and their receptors in normal and abnormal prenatal development complements other chapters discussing morphogenesis, anthropomorphization, and human risk assessment. This book should be a valuable resource for those concerned with experimental teratology and risk assessment and those requiring general information about the causes of birth defects. The treatment of these issues is sophisticated, succinct, and logical. Raymond D. Harbison
Advances in Nutritional Research (Voh 6) Harold H. Draper (editor) New York, 1984, Plenum, 355 pages. Price $49.50 (From American Scientist 73: 392, 1985.)
The discussions included in this annual volume will be Of particular interest to clinical and experimental nutritionists and biochemists seeking well-reasoned assessments of the status of selected pertinent nutritional problems. Consideration is given to current clinical implications of the selenium-related Keshan disease, of su-
Richard M. Forbes
Research abstracts What is a Skeletal Open Bite? R. M. Bryant, A. Jacobson, and P. L. Sadowsky University of Alabama School of Dentistry, Tuscaloosa, 1985
Skeletal open bite pattern has become relatively well-accepted terminology referring to a specific set of morphologic facial skeletal characteristics. There are, however, those persons who exhibit many of these characteristics yet have a normal or deep vertical overbite. This investigation was undertaken to compare cephalometrically a group of subjects exhibiting hyperdivergent skeletal patterns and open bites with a group exhibiting hyperdivergent skeletal patterns and non-open bites. A sample of 60 patients was chosen, all of whom exhibited a mandibular plane angle of 36.5 ° or greater. Of these 60 patients, 34 exhibited open bites and 26 had normal to deep bites. A series of 22 cephalometric measurements were taken from the pretreatment cephalometric radiogram of each subject. In addition, the Jacobson template analysis was performed for each cephalometric radiogram. The results revealed the following differences: (1) the open bites had increased lower face height, (2) the palatal plane relative to sella nasion was less steeply inclined in the open bites, (3) the maxillary and mandibular incisors were more proclined in the open bites, (4) the anterior cranial base (S-N) inclination relative to the soft-tissue profile tended to be steeper in the non-open bites. The nonopen bites on average exhibited less divergency between the palatal and mandibular planes and more dentoalveolar compensation than the open bite group. These findings suggest that the mandibular plane to sella nasion angle is not always an accurate indicator of facial divergency.