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Laboratoriumsdiagnose hämatologischer erkrankungen 1. Hämatologie und immunhämatologie
178
JIM 03379
Laboratoriumsdiagnose hamatologischer Erkrankungen 1. H~tmatologie und Immunh~matologie, by H. Huber, D. Pastner and F. Gabl. Springer-Verlag, BerlinHeidelberg, 1983 (xxi + 553 pp., illus.) soft cover, DM 148.-(approx. $57.50) This book, a revised edition of the work originally published in 1972, has been written for practicing physicians as well as laboratory personnel. Accordingly it consists of 2 parts, one containing diagnostic interpretations of different tests and the other detailed descriptions of laboratory methods. The diagnostic part comprises 16 chapters dealing with specific diseases: haemolytic, hypochromic, megaloblastic, and aplastic anaemias, splenomegaly; granulocytic, myelocytic, myeloblastic, and lymphocytic leukaemias, monoclonal gammopathies, SLE, vasculitis, cryoglobulinaemias, primary and secondary immunodeficiencies, neutropenias, lymphomas, monocyte disorders, and amyloidoses. The methods part contains 9 chapters. Ch. M1 includes physicochemical, enzymatic and serological techniques for detecting erythrocyte defects in haemolytic anaemias. Methods for determining serum iron and iron-binding proteins are described in Ch. M2 and those for measuring oxygen binding to haemoglobin in Ch. M3. Tests for vitamin B12 levels in body fluids and blood cells as well as for autoantibodies to gastric parietal cells of pernicious anaemia patients are given in Ch. M4 (with a reference to Ch. M7 on immunofluorescence). Cytochemical techniques used in the diagnosis of leukaemias are described in Ch. M5. Chapter M6 contains procedures for detecting monoclonal prot~'ins and paraproteins in body fluids by immunoelectrophoresis, isolating and characterizing cryoglobulins, and quantitating immunoglobulins by radial immunodiffusion and nephelometry. In Ch. M7 the principle of immunofluorescence is presented, the optical system, preparation of reagents and substrates and the staining procedures are described and illustrated with examples. Methods for isolating and characterizing peripheral blood lymphocytes including [3H]thymidine incorporation, rosetting, immunobeads binding, and immunoperoxidase staining are given in Ch. M8. The last chapter reviews automated techniques used in cell counting and other haematological measurements. The authors, Austrian haematologists, have collaborated with other experts in preparing most of the chapters. The carefully edited text is accompanied by tables, graphs, schematic diagrams, and photomicrographs. It is provided with bibliographic references, a glossary of abbreviations, and a comprehensive subject index. Readers of both professional categories for whom this volume is intended can find herein the required information. F. Borek
0022-1759/85/$03.30 © 1985 ElsevierSciencePublishersB.V. (BiomedicalDivision)
JIM 03379
Laboratoriumsdiagnose hamatologischer Erkrankungen 1. H~tmatologie und Immunh~matologie, by H. Huber, D. Pastner and F. Gabl. Springer-Verlag, BerlinHeidelberg, 1983 (xxi + 553 pp., illus.) soft cover, DM 148.-(approx. $57.50) This book, a revised edition of the work originally published in 1972, has been written for practicing physicians as well as laboratory personnel. Accordingly it consists of 2 parts, one containing diagnostic interpretations of different tests and the other detailed descriptions of laboratory methods. The diagnostic part comprises 16 chapters dealing with specific diseases: haemolytic, hypochromic, megaloblastic, and aplastic anaemias, splenomegaly; granulocytic, myelocytic, myeloblastic, and lymphocytic leukaemias, monoclonal gammopathies, SLE, vasculitis, cryoglobulinaemias, primary and secondary immunodeficiencies, neutropenias, lymphomas, monocyte disorders, and amyloidoses. The methods part contains 9 chapters. Ch. M1 includes physicochemical, enzymatic and serological techniques for detecting erythrocyte defects in haemolytic anaemias. Methods for determining serum iron and iron-binding proteins are described in Ch. M2 and those for measuring oxygen binding to haemoglobin in Ch. M3. Tests for vitamin B12 levels in body fluids and blood cells as well as for autoantibodies to gastric parietal cells of pernicious anaemia patients are given in Ch. M4 (with a reference to Ch. M7 on immunofluorescence). Cytochemical techniques used in the diagnosis of leukaemias are described in Ch. M5. Chapter M6 contains procedures for detecting monoclonal prot~'ins and paraproteins in body fluids by immunoelectrophoresis, isolating and characterizing cryoglobulins, and quantitating immunoglobulins by radial immunodiffusion and nephelometry. In Ch. M7 the principle of immunofluorescence is presented, the optical system, preparation of reagents and substrates and the staining procedures are described and illustrated with examples. Methods for isolating and characterizing peripheral blood lymphocytes including [3H]thymidine incorporation, rosetting, immunobeads binding, and immunoperoxidase staining are given in Ch. M8. The last chapter reviews automated techniques used in cell counting and other haematological measurements. The authors, Austrian haematologists, have collaborated with other experts in preparing most of the chapters. The carefully edited text is accompanied by tables, graphs, schematic diagrams, and photomicrographs. It is provided with bibliographic references, a glossary of abbreviations, and a comprehensive subject index. Readers of both professional categories for whom this volume is intended can find herein the required information. F. Borek
0022-1759/85/$03.30 © 1985 ElsevierSciencePublishersB.V. (BiomedicalDivision)