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Innere Erkrankungen und Auge
780
AMERICAN JOURNAL OF OPHTHALMOLOGY
retina were based. The volumes were soon translated into English and were rapidly out
of print. The present text is in English and brings the earlier report up to date. The authors are the same with the addition of A. T. Franceschetti, of Geneva, as a collaborator. The new volume supplements rather than replaces the earlier work. The references have been largely retained but brought up to date. The bibliographies are comprehensive and essential to anyone seeking to review and describe hereditary abnormalities of the fundi. Many of the reviews have been re written and provide a systematic discussion rather than a listing of earlier reports as in the first volumes. An economy of words makes this edition some 300 pages shorter than the first. The 53 color plates of the first edition are retained and are beautifully re produced. The book is highly recommended and is a must for all of those who manage hereditary and choroidal diseases. FRANK W.
OEIL
E T CORTISONE.
By
Ph.
NEWELL
Demailly,
H. Hamard, and J.-P. Luton. SaintGermain, Paris, Masson et Cie, Editeurs, 1975. Paperbound, 362 pages, table of con tents, index, 158 black and white figures. Vast experience with corticosteroids has been acquired throughout the world and much involves the ocular effects. With the cooperation of 17 others, Demailly, Hamard, and Luton have gathered, organized, and critically evaluated much of this worldwide information. To conserve space, only se lected references are reviewed by the various authors. As in most previous reviews of this subject, the authors start with hypothalamichypophyseal-adrenal axis, then deal with the structure, actions, and regulation of the adrenocorticotropic hormone. In a historical fashion, they review the synthesis of corti sone, its transport, metabolism, biological, and metabolic effects. The metabolic effects
OCTOBER, 1975
of other corticosteroids on various tissues and systems of the body are summarized. In several chapters, the pharmacologic and physiologic function of the agents includ ing ACTH and their side effects are dealt with in detail. In specific fashion, the authors review the penetration of a variety of corticoste roids, particularly dexamethasone when topically applied as an acetate, alcohol, or phosphate preparation. This deals with ex perimental animal studies. Several chapters consider treatment of conjunctival, corneal, and uveal disorders including keratoplasties and scarring. During the course of these discussions, the role of corticosteroids as immunosuppressive agents is detailed and its comparison to other immunosuppressors evaluated. Specific attention is paid to the side effects of corticosteroids on glaucoma, lens, mucopolysaccharides of the angles, exophthalmos, and the neuro-ophthalmologic tissues. This is a particularly good review for those who are knowledgable in French. For those limited to the English language, there are other publications that cover the informa tion so well documented in this one. Inter estingly, the opinions held by those working in the French-speaking countries are similar to those expressed independently in the United States. It is always helpful to review side effects and possible mechanisms for production. Perhaps by such a review, one can identify the specific cause of each of these side effects. This may lead to concepts for the development of agents free of these complications. IRVING H.
INNERE
ERKRANKUNGEN
UND
LEOPOLD
AUGE.
By
Andreas Heydenreich. Leipzig, VEB Georg Thieme, 1975. Clothbound, 310 pages, table of contents, index, 106 black and white figures. $25.80 This is a short book that contains in an
781
BOOK REVIEWS
VOL. 80, NO. 4
abbreviated form a summary of various eye signs and symptoms in systemic diseases. These signs and symptoms are presented in tables or as abbreviated highlights. While there is no attempt made to cover any topic in depth, the summary-like pre sentation mav be useful for medical students and residents. The bibliography is adequate though in general it does not go beyond 1970. Some of the modern developments of many of the conditions are not considered, but the older literature is certainly well summarized. The book also contains some chapters on neuro-ophthalmology, the metastases of ocular tumors, and toxic effects on the eye. The differential diagnostic tables at the end of the book may be of some benefit to medical students. FREDERICK C. BLODI
By Robison D. Harley. W. B. Saunders Co., 1975. Clothbound, 1112 pages, table of contents, in dex, 877 black and white figures, 14 color plates. $55
PEDIATRIC OPHTHALMOLOGY.
Dr. Harley initiated the cooperation of some 40 eminent ophthalmologists, pediatri cians, dermatologists, radiologists, anesthesi ologists, and the like who presently or were
in the past associated with Wills Eye Hos pital to write this text on pediatric ophthal mology. It is all-encompassing, touching such diverse subjects as anesthesiology of the child and education of the visually handicapped, dental changes and pediatric syndromes, tu mors, and trauma. The book is addressed to the resident and to the practicing ophthal mologist. It gives excellent photographic and schematic presentations. Most sections are extensively referenced and help the interested to find recent screened relevant literature. Wide use has been made of tabulations cor relating ocular abnormalities with systemic findings. These tables should prove very use ful for the practicing pediatric ophthalmolo gist worried about syndrome identification or in case syndrome identification has been made about extraocular complications. The book extensively refers to inherited ocular and systemic diseases with ocular complications. Here, unfortunately, many omissions occur and throughout the book, the description of syndromes—their inheritance, systemic mani festations—are inaccurate in many instances. The basic context of the book—its orienta tion, the material included, its comprehensive ness—should prove useful for the student as well as the practitioner. However, there are evident shortcomings in nosology and clinical descriptions, which definitely limits the use fulness of this book. IRENE H.
MAUMENEE
AMERICAN JOURNAL OF OPHTHALMOLOGY
retina were based. The volumes were soon translated into English and were rapidly out
of print. The present text is in English and brings the earlier report up to date. The authors are the same with the addition of A. T. Franceschetti, of Geneva, as a collaborator. The new volume supplements rather than replaces the earlier work. The references have been largely retained but brought up to date. The bibliographies are comprehensive and essential to anyone seeking to review and describe hereditary abnormalities of the fundi. Many of the reviews have been re written and provide a systematic discussion rather than a listing of earlier reports as in the first volumes. An economy of words makes this edition some 300 pages shorter than the first. The 53 color plates of the first edition are retained and are beautifully re produced. The book is highly recommended and is a must for all of those who manage hereditary and choroidal diseases. FRANK W.
OEIL
E T CORTISONE.
By
Ph.
NEWELL
Demailly,
H. Hamard, and J.-P. Luton. SaintGermain, Paris, Masson et Cie, Editeurs, 1975. Paperbound, 362 pages, table of con tents, index, 158 black and white figures. Vast experience with corticosteroids has been acquired throughout the world and much involves the ocular effects. With the cooperation of 17 others, Demailly, Hamard, and Luton have gathered, organized, and critically evaluated much of this worldwide information. To conserve space, only se lected references are reviewed by the various authors. As in most previous reviews of this subject, the authors start with hypothalamichypophyseal-adrenal axis, then deal with the structure, actions, and regulation of the adrenocorticotropic hormone. In a historical fashion, they review the synthesis of corti sone, its transport, metabolism, biological, and metabolic effects. The metabolic effects
OCTOBER, 1975
of other corticosteroids on various tissues and systems of the body are summarized. In several chapters, the pharmacologic and physiologic function of the agents includ ing ACTH and their side effects are dealt with in detail. In specific fashion, the authors review the penetration of a variety of corticoste roids, particularly dexamethasone when topically applied as an acetate, alcohol, or phosphate preparation. This deals with ex perimental animal studies. Several chapters consider treatment of conjunctival, corneal, and uveal disorders including keratoplasties and scarring. During the course of these discussions, the role of corticosteroids as immunosuppressive agents is detailed and its comparison to other immunosuppressors evaluated. Specific attention is paid to the side effects of corticosteroids on glaucoma, lens, mucopolysaccharides of the angles, exophthalmos, and the neuro-ophthalmologic tissues. This is a particularly good review for those who are knowledgable in French. For those limited to the English language, there are other publications that cover the informa tion so well documented in this one. Inter estingly, the opinions held by those working in the French-speaking countries are similar to those expressed independently in the United States. It is always helpful to review side effects and possible mechanisms for production. Perhaps by such a review, one can identify the specific cause of each of these side effects. This may lead to concepts for the development of agents free of these complications. IRVING H.
INNERE
ERKRANKUNGEN
UND
LEOPOLD
AUGE.
By
Andreas Heydenreich. Leipzig, VEB Georg Thieme, 1975. Clothbound, 310 pages, table of contents, index, 106 black and white figures. $25.80 This is a short book that contains in an
781
BOOK REVIEWS
VOL. 80, NO. 4
abbreviated form a summary of various eye signs and symptoms in systemic diseases. These signs and symptoms are presented in tables or as abbreviated highlights. While there is no attempt made to cover any topic in depth, the summary-like pre sentation mav be useful for medical students and residents. The bibliography is adequate though in general it does not go beyond 1970. Some of the modern developments of many of the conditions are not considered, but the older literature is certainly well summarized. The book also contains some chapters on neuro-ophthalmology, the metastases of ocular tumors, and toxic effects on the eye. The differential diagnostic tables at the end of the book may be of some benefit to medical students. FREDERICK C. BLODI
By Robison D. Harley. W. B. Saunders Co., 1975. Clothbound, 1112 pages, table of contents, in dex, 877 black and white figures, 14 color plates. $55
PEDIATRIC OPHTHALMOLOGY.
Dr. Harley initiated the cooperation of some 40 eminent ophthalmologists, pediatri cians, dermatologists, radiologists, anesthesi ologists, and the like who presently or were
in the past associated with Wills Eye Hos pital to write this text on pediatric ophthal mology. It is all-encompassing, touching such diverse subjects as anesthesiology of the child and education of the visually handicapped, dental changes and pediatric syndromes, tu mors, and trauma. The book is addressed to the resident and to the practicing ophthal mologist. It gives excellent photographic and schematic presentations. Most sections are extensively referenced and help the interested to find recent screened relevant literature. Wide use has been made of tabulations cor relating ocular abnormalities with systemic findings. These tables should prove very use ful for the practicing pediatric ophthalmolo gist worried about syndrome identification or in case syndrome identification has been made about extraocular complications. The book extensively refers to inherited ocular and systemic diseases with ocular complications. Here, unfortunately, many omissions occur and throughout the book, the description of syndromes—their inheritance, systemic mani festations—are inaccurate in many instances. The basic context of the book—its orienta tion, the material included, its comprehensive ness—should prove useful for the student as well as the practitioner. However, there are evident shortcomings in nosology and clinical descriptions, which definitely limits the use fulness of this book. IRENE H.
MAUMENEE