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Medicinal chemistry: An introduction
Book reviews
from a biosynthetic perspective. It is divided into eight sections. 1. About this book and how to use it. 2. Secondary Metabolism: The Building Blocks and Construction Mechanisms. 3. The Acetate Pathway: Fatty Acids and Polyketides. 4. The Shikimate Pathway: Aromatic Amino Acids and Phenylpropanoids. 5. The Mevalonate and Deoxyxylulose Phosphate Pathways: Terpenoids and Steroids. 6. Alkaloids. 7. Peptides, Proteins and other Amino Acids Derivatives. 8. Carbohydrates. It has been written primarily for Pharmacy students but should be of value for scientists in the area of Natural Products. PII: S0223-5234(0 l)01302-2/BRV
Medicinal chemistry: An introduction Edited by Gareth Thomas, Wiley, Chichester, 2000. 540 pp.; £24.95
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967
Nitric Oxide Synthase Inhibition. Predicting DMPK.
PII: S0223-5234(01)01304-6/BRV
Membrane structure in disease and drug therapy Edited by Guido Zimmer, Marcel Dekker, New York, 2000. 530 pp.; $195
With the contributions of over 60 contributors, Membrane Structure in Disease and Drug Therapy describes interaction with membranous transport systems, details reactions with membrane-imbedded receptors, discusses activation or inhibition of membrane enzymes and cytosolic-membranous signaling and exchange, outlines antibacterial and hemolytic actions of helical peptides, emphasizes the structure and function of membranes in oxidative stress and the links to Alzheimer's disease, studies membrane-associated proteins involved in autosomal dominant polycystic kidney disease, focuses on insulin action, the glucose-6-phosphatase enzyme, and cystic fibrosis. PII: S0223-5234(01)01305-8/BRV
This book provides an introduction to the field. It explains fundamental principles, focusing on the chemical principles used for drug discovery and design and also covers human biology where relevant. Each chapter has a summary of its contents, self-assessment questions, examples and applications. PII: S0223-5234(01)01303-4/BRV
Medicinal chemistry into the millennium Edited by M.M. Campbell, I.S. Blagbrough, Proceedings of the European Federation of Medicinal Chemistry Symposium held in Edinburgh on 6-11 September, 1998, RS.C, Cambridge, 2001. 397 pp.
Contents - New Technologies for Drug Discovery. - Ion Channels. - Glycine Antagonists. - 7TM Receptors. - Growth Factors. - Intracellular Signalling. - Protease Inhibition. - Glycochemistry and Glycobiology.
Pharmaceuticals, classes, therapeutic agents, areas of application Edited by J.L. McGuire, Wiley-VCH, Weinheim, 2000
Volume 1, Introduction, cardiovascular drugs, 303 pp. Contents 1. The Pharmaceutical Industry. 2. Cardioactive and Vasoactive Drugs. 3. Blood Pressure Increasing Agents. 4. Antihypertensive Agents. 5. Antiarrhythmic Drugs. 6. Beta Blockers. 7. Cardiac Glycosides and Synthetic Cardiotonic Drugs. 8. Calcium Antagonists. 9. Drugs Affecting Circulation. 10. Blood. 11. Diuretics.
Volume 2, Neuropharmaceuticals, gastrointestinal drugs, respiratory tract Contents: 1. Neuropharmaceutical Agents. 2. Analeptics. 3. Analgesics and Antipyretics.
from a biosynthetic perspective. It is divided into eight sections. 1. About this book and how to use it. 2. Secondary Metabolism: The Building Blocks and Construction Mechanisms. 3. The Acetate Pathway: Fatty Acids and Polyketides. 4. The Shikimate Pathway: Aromatic Amino Acids and Phenylpropanoids. 5. The Mevalonate and Deoxyxylulose Phosphate Pathways: Terpenoids and Steroids. 6. Alkaloids. 7. Peptides, Proteins and other Amino Acids Derivatives. 8. Carbohydrates. It has been written primarily for Pharmacy students but should be of value for scientists in the area of Natural Products. PII: S0223-5234(0 l)01302-2/BRV
Medicinal chemistry: An introduction Edited by Gareth Thomas, Wiley, Chichester, 2000. 540 pp.; £24.95
-
967
Nitric Oxide Synthase Inhibition. Predicting DMPK.
PII: S0223-5234(01)01304-6/BRV
Membrane structure in disease and drug therapy Edited by Guido Zimmer, Marcel Dekker, New York, 2000. 530 pp.; $195
With the contributions of over 60 contributors, Membrane Structure in Disease and Drug Therapy describes interaction with membranous transport systems, details reactions with membrane-imbedded receptors, discusses activation or inhibition of membrane enzymes and cytosolic-membranous signaling and exchange, outlines antibacterial and hemolytic actions of helical peptides, emphasizes the structure and function of membranes in oxidative stress and the links to Alzheimer's disease, studies membrane-associated proteins involved in autosomal dominant polycystic kidney disease, focuses on insulin action, the glucose-6-phosphatase enzyme, and cystic fibrosis. PII: S0223-5234(01)01305-8/BRV
This book provides an introduction to the field. It explains fundamental principles, focusing on the chemical principles used for drug discovery and design and also covers human biology where relevant. Each chapter has a summary of its contents, self-assessment questions, examples and applications. PII: S0223-5234(01)01303-4/BRV
Medicinal chemistry into the millennium Edited by M.M. Campbell, I.S. Blagbrough, Proceedings of the European Federation of Medicinal Chemistry Symposium held in Edinburgh on 6-11 September, 1998, RS.C, Cambridge, 2001. 397 pp.
Contents - New Technologies for Drug Discovery. - Ion Channels. - Glycine Antagonists. - 7TM Receptors. - Growth Factors. - Intracellular Signalling. - Protease Inhibition. - Glycochemistry and Glycobiology.
Pharmaceuticals, classes, therapeutic agents, areas of application Edited by J.L. McGuire, Wiley-VCH, Weinheim, 2000
Volume 1, Introduction, cardiovascular drugs, 303 pp. Contents 1. The Pharmaceutical Industry. 2. Cardioactive and Vasoactive Drugs. 3. Blood Pressure Increasing Agents. 4. Antihypertensive Agents. 5. Antiarrhythmic Drugs. 6. Beta Blockers. 7. Cardiac Glycosides and Synthetic Cardiotonic Drugs. 8. Calcium Antagonists. 9. Drugs Affecting Circulation. 10. Blood. 11. Diuretics.
Volume 2, Neuropharmaceuticals, gastrointestinal drugs, respiratory tract Contents: 1. Neuropharmaceutical Agents. 2. Analeptics. 3. Analgesics and Antipyretics.