Nomenclature for factors of the HLA system, update October 2014

Human Immunology 76 (2015) 192–194

Contents lists available at ScienceDirect

www.ashi-hla.org

journal homepage: www.elsevier.com/locate/humimm

Nomenclature for factors of the HLA system, update October 2014 Compiled by Steven G.E. Marsh ⇑ for the WHO Nomenclature Committee for Factors of the HLA System

The following sequences have been submitted to the Nomenclature Committee since the September 2014 nomenclature update and, following agreed policy, have been assigned official allele designations [1]. Full details of all sequences will be published in a forthcoming report. Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The

accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly.

Table 1 New sequences. HLA allele

Cell identification

Accession number

Submitting author

A⁄11:210N A⁄26:106 A⁄26:107N A⁄29:75 A⁄31:01:02:02 B⁄07:235 B⁄07:236 B⁄08:138 B⁄49:34 B⁄51:185 B⁄54:34 B⁄55:02:01:02 B⁄56:01:01:02 B⁄58:67 C⁄05:108 C⁄16:77N DRB1⁄04:05:17 DRB1⁄04:05:18 DRB1⁄08:03:05 DRB1⁄08:61 DRB1⁄08:62 DRB1⁄08:63 DRB1⁄08:63 DRB1⁄12:52 DRB1⁄13:194 DRB1⁄14:04:02 DQB1⁄03:03:02:04 DQB1⁄05:87Q E⁄01:03:01:03 E⁄01:08N

CTM8026638 23462, RMC26119 9711052 FRFGR33525 CTM 1026127 BY01145 UKT NGS 002 81126682 14001440 81127544 P08700 TU01 TU02 7711106200 49381 93095106 D10075231 DK1561 BE7610 DA8331 DV2595 CTJ-20255 D11050140 BE7520 LIG 90004 D10049542 MAT-92 B00910 4395 4395

KM657949 LN614521 KM979288 LN558515 KM879189 KF649107 LC004128 KM875664 KJ941004 KM875663 KM658169 AB679915 AB679916 KM609464 KM657022 KM875665 HE654732 LN609297 LN609290 LN609296 LN609298 EU545182 KF270568 LN609289 KM591601 HE654759 KM519596 KC970437 LM654512 LM654513

Antonio Balas, Madrid, Spain Maria Loginova, Kirov, Russia Francisco de Paula Sanchez Gordo, Malaga, Spain Dominique Masson, La Tronche, France Antonio Balas, Madrid, Spain Carolyn K Hurley, Washington DC, USA Alexandr Kuranov, Tübingen, Germany Daniel Fuerst, Ulm, Germany Antonio Balas, Madrid, Spain Daniel Fuerst, Ulm, Germany Faming Zhu, Hangzhou, China Takashi Shiina, Isehara, Japan Takashi Shiina, Isehara, Japan Yan Liao, Nanning, China Runying Tian, Durham, USA Daniel Fuerst, Ulm, Germany Jinghui Qu, Shenzhen, China Xiang Liu, Beijing, China Xiang Liu, Beijing, China Xiang Liu, Beijing, China Xiang Liu, Beijing, China Lina Yan, Tianjin, China Jinghui Qu, Shenzhen, China Xiang Liu, Beijing, China Maria Elisa Moraes, Rio de Janeiro, Brazil Jinghui Qu, Shenzhen, China Jorge Martinez-Laso, Madrid, Spain Keming Du, Shanghai, China Marcel GJ Tilanus, Maastricht, The Netherlands Marcel GJ Tilanus, Maastricht, The Netherlands

⇑ Address for correspondence: Professor Steven G.E. Marsh, Anthony Nolan Research Institute, Royal Free Hospital, Pond Street, London NW3 2QG, United Kingdom. Tel.: +44 20 7284 8321; fax: +44 20 7284 8331. E-mail address: [email protected] URLs: https://www.hla.alleles.org, https://www.anthonynolan.org/hig, https://www.ebi.ac.uk/ipd/imgt/hla. http://dx.doi.org/10.1016/j.humimm.2015.01.004 0198-8859/Ó 2015 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

193

S.G.E. Marsh / Human Immunology 76 (2015) 192–194 Table 2 Confirmatory sequences. HLA allele

Cell identification

Accession number

Submitting author

A⁄02:01:74 A⁄02:486 A⁄23:65 A⁄24:248 B⁄15:268 B⁄15:332 B⁄18:45 B⁄35:144 B⁄35:158 B⁄40:130:02 B⁄41:29 B⁄51:160 B⁄51:168 B⁄57:73 C⁄05:01:29 C⁄06:127:01 C⁄06:133 C⁄07:02:52 C⁄07:02:63 C⁄07:381 C⁄07:397 DRB1⁄03:01:20 DRB1⁄03:04:01 DRB1⁄04:14 DRB1⁄04:100 DRB1⁄04:182 DRB1⁄07:26N DRB1⁄08:30:03 DRB1⁄11:13:02 DRB1⁄12:48 DRB1⁄14:17 DQB1⁄02:41 DQB1⁄03:02:06 DQB1⁄03:02:13 DQB1⁄03:139 DQB1⁄05:03:14 DQB1⁄05:11:02 DQB1⁄05:20 DQB1⁄05:49 DQB1⁄05:52 DQB1⁄05:69 DQB1⁄05:75 DQB1⁄06:02:20 DQB1⁄06:22:03 DQB1⁄06:125 DQB1⁄06:126 DQB1⁄06:153 DQB1⁄06:155 DPB1⁄04:01:14 DPB1⁄11:01:03 DPB1⁄177:01 DPB1⁄182:01 DPB1⁄184:01 DPB1⁄210:01 DPB1⁄218:01N DPB1⁄301:01 DPB1⁄309:01 DPB1⁄329:01 DPB1⁄357:01N DPB1⁄365:01 DPB1⁄369:01 DPB1⁄382:01N

BY00906 HG00009201 HG00009200 Beijing22607 HG00009208 HG00009207 HG00009204 HG00009206 HG00009205 HG00009202 4307681 BY01204 HG00009209 HG00009203 HG00009215 HG00009210 HG00009211 HG00009213 120821109 HG00009214 HG00009212 HG00009242 27895 38210 D10002408 HG00009241 DKMS-LSL-DRB1-41 D10071082 29585 8811000959 #15310-LN HG00009218, HG00009219 HG00009224 HG00009222, HG00009223 HG00009217 HG00009232 HG00009230, HG00009231 HG00009228 HG00009235 HG00009225, HG00009226, HG00009227 HG00009233, HG00009234 HG00009229 HG00009239 HG00009238 HG00009237 HG00009240 HG00009216 HG00009220, HG00009221 HG00009256, HG00009257 HG00009259 HG00009247 HG00009249 HG00009251, HG00009252 HG00009243 HG00009255 HG00009244 HG00009253 HG00009260 HG00009248 HG00009250 HG00009258 HG00009254

JQ040000 KM198115 KM198204 KC473543 KF790850 KM051859 KF790851 KF790855 KF790852 KM198209 HG934987 KJ418364 KM248726 KM216193 KJ749782 KM216197 KM198222 KM198146 HG934781 KM365111 KM216196 KJ619556 LM611904 HG974603 HE654736 KM198167 HF937425 HE654739 LM611905 KM382430 HG974602 KM198234, KM198157 KM198228, KM198165 KM454992 KM248735, KJ190374 KM365116 KM248738, KM454993, KM198161 KM248732 KM248739 KM198150 KM198163 KM198164 KM454995, KM198191, KM365122 KM216213 KM198192 KM198186, KM198178 KM198170 KM198184 KM198174 KM365124 KM248742 KM198243 KJ956777 KM198168

Carolyn K Hurley, Washington DC, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Xiaoyan Shan, Beijing, China Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Paul Dunn, Auckland, New Zealand Carolyn K Hurley, Washington DC, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Dominique Masson, La Tronche, France Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Marcel GJ Tilanus, Maastricht, The Netherlands Marcel GJ Tilanus, Maastricht, The Netherlands Jinghui Qu, Shenzhen, China Histogenetics, Ossining, USA DKMS Life Sciences Lab, Dresden, Germany Jinghui Qu, Shenzhen, China Marcel GJ Tilanus, Maastricht, The Netherlands Huafang Gao, Beijing, China Marcel GJ Tilanus, Maastricht, The Netherlands Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA Histogenetics, Ossining, USA

Table 3 Recently published sequences. HLA allele

References

A⁄02:05:01 A⁄02:06:01 A⁄11:101 A⁄11:188 A⁄11:192 B⁄08:132 B⁄15:325 B⁄37:06:02 B⁄55:50 DRB1⁄15:02:11

[4] [4] [5] [6] [7] [8] [9] [10] [11] [12]

KM198151 KM454994

KM248734

KM198154, KM248731 KM198155

KM198231 KM198182

KM198244

Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3. An additional 372 alleles were recently published but have not been included in Table 3 due to space considerations [2]. All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IMGT/HLA Database using the sequence submission tool provided [3]. The IMGT/HLA Database may be accessed via the World Wide Web at: www.ebi.ac.uk/ipd/imgt/hla.

194

S.G.E. Marsh / Human Immunology 76 (2015) 192–194

References [1] Marsh SGE, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, et al. Nomenclature for factors of the HLA system, 2010. Tissue Antigens 2010;75(4):291–455. [2] Hernandez-Frederick CJ, Cereb N, Giani AS, Ruppel J, Maraszek A, Pingel J, et al. Three hundred and seventy-two novel HLA class II alleles identified in potential hematopoietic stem cell donors from Germany, the United States, and Poland. Tissue Antigens 2014;84(5):497–502. [3] Robinson J, Halliwell JA, McWilliam H, Lopez R, Parham P, Marsh SGE. The IMGT/HLA database. Nucleic Acids Res 2013;41(Database issue):D1222–7. [4] Zhang H, Xu YP. Genomic full-length sequence of two HLA-A alleles, A⁄02:05:01 and A⁄02:06:01 identified by cloning and sequencing. Tissue Antigens 2014;84(5):505–7. [5] Zhang X, Li XF, Lin FQ, Zhang KL, Li JP. Identification of a novel HLA allele, HLAA⁄11:101, in a platelet donor from China. Tissue Antigens 2014;84(5):508–9. [6] Li Z, Lu L, Nie D, Wu J, Zhang H, Zhen J, et al. HLA-A⁄11:188: a new allele identified by sequence-based typing in a Chinese blood donor. Tissue Antigens 2014;84(5):512–3.

[7] Todorova K, Zuber K, Neuwirt P, Arnold R, Schonemann C, Schulze H. Identification of the novel HLA-A⁄11:192 allele by HLA typing of a Caucasian individual. Tissue Antigens 2014;84(5):509–10. [8] Papazoglou A, Gasiewski A, Huynh A, Duke J, Ferriola D, Rogers M, et al. Identification and characterization of a novel HLA-B hybrid allele, B⁄08:132 with next generation sequencing. Tissue Antigens 2014;84(5):513–4. [9] Ou G, Wang J, Wang C, Ji X, Chen Q. A novel HLA-B allele, HLA-B⁄15:325, is identified by sequence-based typing in a HIV infected individual. Tissue Antigens 2014;84(5):514–5. [10] Li X, Zou H, Gu B, Zhu Y, Chen Q. A novel HLA allele, HLA-B⁄37:06:02, identified in a Chinese family. Tissue Antigens 2014;84(5):516–7. [11] Zhang KL, Li XF, Zhang X, Lin FQ, Li JP. A novel HLA allele, HLA-B⁄55:50, was identified by sequence-based typing. Tissue Antigens 2014;84(5):517–8. [12] Yang KL, Lee SK, Hung JH, Lin PY. HLA-DRB1⁄15:02:11, a variant of HLADRB1⁄15:02:01, revealed in a Taiwanese patient awaiting hematopoietic stem cell transplantation. Tissue Antigens 2014;84(5):519–20.