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P146-1: Frailty and health-related quality of life in ambulatory older men
S128
Poster presentations, Thursday 18 September 2014 / European Geriatric Medicine 5S1 (2014) S83–S158
Mean gait speed changed from 0.33 m/s (baseline) to 0.39 m/s (p = 0.047), from 0.29 m/s to 0.42 m/s (p = 0.024), and from 0.34 m/s to 0.36 m/s (p = 0.450) whereas mean grip strength changed from 4 kg (baseline) to 5 kg (p = 0.180), from 5.17 kg to 12.17 kg (p = 0.027) and from 2.6 kg to 2.2 kg (p = 0.713) in groups A, B and C respectively. Mean frailty score changed from 5.0 to 3.0 (p = 0.131), from 4.67 to 2.67 (p = 0.034), and from 4.4 to 4.0 (p = 0.157) in groups A, B and C respectively. Conclusion: Frail elderly must receive both nutritional as well as exercise intervention for the alleviation of their frail status. Exercise intervention in the form of nordic walking can be an attractive option for significant functional improvement in frail older patients. P144 The association of frailty with serum 25-hydroxyvitamin D in older men L. de Buyser, M. Petrovic, Y.E. Taes, K. Toye, J.M. Kaufman, S. Goemaere Ghent University, Ghent, Belgium Introduction: The aim of this study was to determine the association of frailty with serum 25-hydroxyvitamin D in a population-based sample of older men. Methods: Cross-sectional analyses were performed on data from a longitudinal study in 264 ambulatory men aged 72 to 87 years and registered in the community of Merelbeke (Ghent, Belgium) in 1997. Frailty status (robust vs. prefrail or frail) was assessed using the Study of Osteoporotic Fractures (SOF) index with the components of weight loss, inability to rise from a chair 5 times without using arms, and reduced energy level. Serum 25-hydroxyvitamin D was determined after extraction by radioimmunoassay. Low 25hydroxyvitamin D level was defined as <30 ng/ml. Logistic regression models adjusted for age and body mass index examined the relationship between (low) 25-hydroxyvitamin D level and (pre)frailty. Results: Mean age was 76.7±3.9 years. According to the SOF index, 181 men (69%) were robust, 79 men (30%) were prefrail or frail. Serum 25-hydroxyvitamin D concentration was significantly associated with (pre)frailty (OR per ng/ml decrease = 1.05, 95% CI = 1.01–1.09, P = 0.009). Older men with low 25-hydroxyvitamin D levels had 2.7 times more odds of being (pre)frail than older men with normal 25-hydroxyvitamin D levels (OR = 2.71, 95% CI = 1.38– 5.40, P = 0.005). Key conclusions: Our findings suggest that lower serum 25hydroxyvitamin D levels are associated with (pre)frailty in older men. P145 Nutrition plays a gender-dependent role in disability in an elderly Sardinian population D. Concu, G.M. Pes University of Sassari, Italy Introduction: In the elderly population the disability rate is lower in men than in women, although in the latter life expectancy in generally higher. In Sardinia island a remarkable gender equality in mortality has been reported (Poulain et al., 2004), but it is not known if this also holds true for disability. We evaluated the disability level in a sample of elderly subjects and correlated it with lifestyle and socio-demographic variables. Subjects and Methods: One-hundred subjects (50% men, aged 78–93) recruited in the island’s main cities. A comprehensive assessment was carried out in each participant: ADL, IADL, Barthel index, MMSE, Exton-Smith and Tinetti scale, km/wk and MNA. The association of predictors with disability was performed by multiple linear regression analysis. Results: Among women the strongest predictors of disability, as reflected by IADL, were MNA (p = 0.0001), SPMSQ (p = 0.004) and Tinetti score (p = 0.001), whereas in males physical activity
expressed as km/wk (p = 0.039), the Exton-Smith score (p = 0.0001) and MMSE (p = 0.001) were the most important predictors. Conclusion: These results suggest that IADL disability in males is mostly linked to cognitive and motor impairment, whereas in women is influenced also by a concomitant malnutrition. We suggest that physical activity is a protective factor for disability in men, while women lacking this protective mechanism are more vulnerable to a nutritional deficiency. P146-1 Frailty and health-related quality of life in ambulatory older men L. de Buyser, M. Petrovic, Y.E. Taes, K. Toye, J.M. Kaufman, S. Goemaere Ghent University, Ghent, Belgium Introduction: The aim of this study was to investigate the relationship between frailty status and health-related quality of life in a population-based sample of ambulatory older men. Methods: Cross-sectional analyses were performed on data from a longitudinal study in 260 ambulatory men aged 72 to 87 years and registered in the community of Merelbeke (Ghent, Belgium) in 1997. Frailty status (robust, prefrail, frail) was assessed using the Study of Osteoporotic Fractures (SOF) index with the components of weight loss, inability to rise from a chair 5 times without using arms, and reduced energy level. Health-related quality of life was assessed using the eight domains of the Short Form-36 questionnaire. Subjects in the lowest quartile of the distribution were classified as having ‘poor’ status for each domain. Logistic regression models adjusted for age examined the relationship between frailty status and poor status on the Short Form-36 domains. Results: Mean age was 76.7±3.9 years. According to the SOF index, 181 men (69%) were robust, 69 men (26%) were prefrail, and 10 men (4%) were frail. The distribution of the Short Form-36 domain scores differed significantly across frailty statuses (Table 1). Prefrailty and frailty were significantly associated with increased prevalence of poor status for all 8 Short-Form 36 domains. Key conclusions: Our findings suggest that both prefrailty and frailty are associated with poorer health-related quality of life in older men, independent of age. Table 1. Scores on the Short Form-36 domains according to frailty status General Health Perception Physical Function Role Physical Bodily Pain General Mental Health Role Emotional Vitality Social Function
All (N = 260) Median IQR
Robust (N = 181) Median IQR
Prefrail (N = 69) Frail (N = 10) Median IQR Median IQR
Pa
65 80 100 90 82 100 75 100
70 90 100 90 84 100 80 100
60 70 75 79 76 100 65 88
<0.001 <0.001 <0.001 0.003 <0.001 <0.001 <0.001 <0.001
55, 75 65, 75 50, 100 67, 100 72, 92 67, 100 65, 85 88, 100
60, 80 75, 95 75, 100 69, 100 72, 96 100, 100 70, 90 88, 100
46, 70 51, 80 0, 100 56, 100 60, 87 33, 100 51, 80 63, 100
48 38 75 55 60 0 40 63
44, 60 19, 81 19, 100 44, 92 52, 70 0, 100 34, 58 34, 78
a Independent Samples Kruskal–Wallis test.
P146 Attitudes and perceptions of adults of 60 years and older towards in-home monitoring of the activities of daily living with contactless sensors: an explorative study V. Claes1 , E. Devriendt1 , J. Tournoy2 , M.D. Deschodt1 , K. Milisen1 1 KU Leuven, Leuven, Belgium; 2 University Hospitals Leuven, Leuven, Belgium Introduction: Contactless monitoring is increasingly used to enhance qualitative and cost-effective care for older persons. Succesful implementation of this technology, depends on its acceptance by older people. The purpose was to explore attitudes and perceptions of adults aged ≥60 years towards contactless monitoring. Methods: A questionnaire was developed, validated and used in a cross-sectional survey with a convenience sample (n = 245). Descriptive and bivariate statistics were used for data analysis.
Poster presentations, Thursday 18 September 2014 / European Geriatric Medicine 5S1 (2014) S83–S158
Mean gait speed changed from 0.33 m/s (baseline) to 0.39 m/s (p = 0.047), from 0.29 m/s to 0.42 m/s (p = 0.024), and from 0.34 m/s to 0.36 m/s (p = 0.450) whereas mean grip strength changed from 4 kg (baseline) to 5 kg (p = 0.180), from 5.17 kg to 12.17 kg (p = 0.027) and from 2.6 kg to 2.2 kg (p = 0.713) in groups A, B and C respectively. Mean frailty score changed from 5.0 to 3.0 (p = 0.131), from 4.67 to 2.67 (p = 0.034), and from 4.4 to 4.0 (p = 0.157) in groups A, B and C respectively. Conclusion: Frail elderly must receive both nutritional as well as exercise intervention for the alleviation of their frail status. Exercise intervention in the form of nordic walking can be an attractive option for significant functional improvement in frail older patients. P144 The association of frailty with serum 25-hydroxyvitamin D in older men L. de Buyser, M. Petrovic, Y.E. Taes, K. Toye, J.M. Kaufman, S. Goemaere Ghent University, Ghent, Belgium Introduction: The aim of this study was to determine the association of frailty with serum 25-hydroxyvitamin D in a population-based sample of older men. Methods: Cross-sectional analyses were performed on data from a longitudinal study in 264 ambulatory men aged 72 to 87 years and registered in the community of Merelbeke (Ghent, Belgium) in 1997. Frailty status (robust vs. prefrail or frail) was assessed using the Study of Osteoporotic Fractures (SOF) index with the components of weight loss, inability to rise from a chair 5 times without using arms, and reduced energy level. Serum 25-hydroxyvitamin D was determined after extraction by radioimmunoassay. Low 25hydroxyvitamin D level was defined as <30 ng/ml. Logistic regression models adjusted for age and body mass index examined the relationship between (low) 25-hydroxyvitamin D level and (pre)frailty. Results: Mean age was 76.7±3.9 years. According to the SOF index, 181 men (69%) were robust, 79 men (30%) were prefrail or frail. Serum 25-hydroxyvitamin D concentration was significantly associated with (pre)frailty (OR per ng/ml decrease = 1.05, 95% CI = 1.01–1.09, P = 0.009). Older men with low 25-hydroxyvitamin D levels had 2.7 times more odds of being (pre)frail than older men with normal 25-hydroxyvitamin D levels (OR = 2.71, 95% CI = 1.38– 5.40, P = 0.005). Key conclusions: Our findings suggest that lower serum 25hydroxyvitamin D levels are associated with (pre)frailty in older men. P145 Nutrition plays a gender-dependent role in disability in an elderly Sardinian population D. Concu, G.M. Pes University of Sassari, Italy Introduction: In the elderly population the disability rate is lower in men than in women, although in the latter life expectancy in generally higher. In Sardinia island a remarkable gender equality in mortality has been reported (Poulain et al., 2004), but it is not known if this also holds true for disability. We evaluated the disability level in a sample of elderly subjects and correlated it with lifestyle and socio-demographic variables. Subjects and Methods: One-hundred subjects (50% men, aged 78–93) recruited in the island’s main cities. A comprehensive assessment was carried out in each participant: ADL, IADL, Barthel index, MMSE, Exton-Smith and Tinetti scale, km/wk and MNA. The association of predictors with disability was performed by multiple linear regression analysis. Results: Among women the strongest predictors of disability, as reflected by IADL, were MNA (p = 0.0001), SPMSQ (p = 0.004) and Tinetti score (p = 0.001), whereas in males physical activity
expressed as km/wk (p = 0.039), the Exton-Smith score (p = 0.0001) and MMSE (p = 0.001) were the most important predictors. Conclusion: These results suggest that IADL disability in males is mostly linked to cognitive and motor impairment, whereas in women is influenced also by a concomitant malnutrition. We suggest that physical activity is a protective factor for disability in men, while women lacking this protective mechanism are more vulnerable to a nutritional deficiency. P146-1 Frailty and health-related quality of life in ambulatory older men L. de Buyser, M. Petrovic, Y.E. Taes, K. Toye, J.M. Kaufman, S. Goemaere Ghent University, Ghent, Belgium Introduction: The aim of this study was to investigate the relationship between frailty status and health-related quality of life in a population-based sample of ambulatory older men. Methods: Cross-sectional analyses were performed on data from a longitudinal study in 260 ambulatory men aged 72 to 87 years and registered in the community of Merelbeke (Ghent, Belgium) in 1997. Frailty status (robust, prefrail, frail) was assessed using the Study of Osteoporotic Fractures (SOF) index with the components of weight loss, inability to rise from a chair 5 times without using arms, and reduced energy level. Health-related quality of life was assessed using the eight domains of the Short Form-36 questionnaire. Subjects in the lowest quartile of the distribution were classified as having ‘poor’ status for each domain. Logistic regression models adjusted for age examined the relationship between frailty status and poor status on the Short Form-36 domains. Results: Mean age was 76.7±3.9 years. According to the SOF index, 181 men (69%) were robust, 69 men (26%) were prefrail, and 10 men (4%) were frail. The distribution of the Short Form-36 domain scores differed significantly across frailty statuses (Table 1). Prefrailty and frailty were significantly associated with increased prevalence of poor status for all 8 Short-Form 36 domains. Key conclusions: Our findings suggest that both prefrailty and frailty are associated with poorer health-related quality of life in older men, independent of age. Table 1. Scores on the Short Form-36 domains according to frailty status General Health Perception Physical Function Role Physical Bodily Pain General Mental Health Role Emotional Vitality Social Function
All (N = 260) Median IQR
Robust (N = 181) Median IQR
Prefrail (N = 69) Frail (N = 10) Median IQR Median IQR
Pa
65 80 100 90 82 100 75 100
70 90 100 90 84 100 80 100
60 70 75 79 76 100 65 88
<0.001 <0.001 <0.001 0.003 <0.001 <0.001 <0.001 <0.001
55, 75 65, 75 50, 100 67, 100 72, 92 67, 100 65, 85 88, 100
60, 80 75, 95 75, 100 69, 100 72, 96 100, 100 70, 90 88, 100
46, 70 51, 80 0, 100 56, 100 60, 87 33, 100 51, 80 63, 100
48 38 75 55 60 0 40 63
44, 60 19, 81 19, 100 44, 92 52, 70 0, 100 34, 58 34, 78
a Independent Samples Kruskal–Wallis test.
P146 Attitudes and perceptions of adults of 60 years and older towards in-home monitoring of the activities of daily living with contactless sensors: an explorative study V. Claes1 , E. Devriendt1 , J. Tournoy2 , M.D. Deschodt1 , K. Milisen1 1 KU Leuven, Leuven, Belgium; 2 University Hospitals Leuven, Leuven, Belgium Introduction: Contactless monitoring is increasingly used to enhance qualitative and cost-effective care for older persons. Succesful implementation of this technology, depends on its acceptance by older people. The purpose was to explore attitudes and perceptions of adults aged ≥60 years towards contactless monitoring. Methods: A questionnaire was developed, validated and used in a cross-sectional survey with a convenience sample (n = 245). Descriptive and bivariate statistics were used for data analysis.