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Subject index volume 17
Cancer Letters, 17 (1983) 353-356 Elsevier Scientific Publishers Ireland Ltd.
353
SUBJECT INDEX Volume 17 Acrylonitrile, hepatocyte-mediated production of sister chromatid exchange in co-cultured cells by, - evidence for extra cellular transport of a stable intermediate, 213 S-Adenosylethionine, nicotinamide methyltransferase inhibition by, 293 Adriamycin, apparent ineffectiveness of, for growth of androgen-dependent Shionogi carcinoma 115 in the mouse, 327 Aggregation, calcium-dependent and calcium-independent, of established and malignant cell lines, 19 Amines, cyclic, as less mutagenic replacements for dimethyl amino substituents on aromatic organic compounds: implications for carcinogenicity and toxicity, 263 4-Aminoazobenzene or 3’-methyl-4dimethylaminoazobenzene, induction of tumors in transplacental or neonatal mice administered, 321 Androgendependent Shionogi carcinoma 115, apparent ineffectiveness of adriamycin for growth of, in the mouse, 327 Anticarcinogenic actions of water-soluble and alcohol-insoluble fractions from culture medium of Lentinus edodes mycelia, 109 Antioxidants and antitoxicants of isoniazid, effect of, on the formation of. lung tumours in mice by isoniazid and hydrazine sulphate, 75 Antitumor effect of palmitoleic acid on Ehrlich ascites tumor, 197 Aromatic organic compounds, cyclic amines as less mutagenic replacements for dimethyl amino substituents on, and implications for carcinogenicity and toxicity, 263 Artificial membranes, binding of tumorpromoting and biologically inactive phorbol esters, 135 Aryl hydrocarbon hydroxylase, low con-
stitutive activity of, in phytohaemoagglutinin-stimulated peripheral blood mononuclear cells of children after treatment for acute lymphoblastic leukemia, 95 Ascorbic acid, failure of, to inhibit growth of transplantable and dimethylbenzanthracene induced rat mammary tumors, 67 Azoxymethane and 1,2-dimethylhydrazine, inhibition of carcinogenicities of, by pyrazole, 147 Beta1 quid chewers, individuals at high risk for oral cancer, elevated frequency of micronucleated cells in the buccal , mucosa of, 125 Biologically inactive and tumor-promoting phorbol esters, binding of, to artificial membranes, 135 Bladder cancer, induction of, in mice, by implanting pellets containing tryptophan pyrolysis products, 101 Buccal mucosa, elevated frequency of micronucleated cells in the, of individuals at high risk: beta1 quid chewers, 125 C3H/He male mice, effect of Konjac mannan on spontaneous liver tumorigenesis and fecal flora in, 27 Calcium-dependent and calcium-independent aggregation of established and malignant cell lines, 19 Carcinogenicities of 1,2_dimethylhydrazine and azoxymethane, inhibition of, by pyrazole, 147 Carcinogenicity of some pyrrolic pyrrolizidine alkaloid metabolites and analogues, 6 1 Cell lines, established and malignant, calcium-dependent and calciumindependent aggregation of, 19 Chrysotile asbestos, effects of, on lung and pleural carcinogenesis of N-bis(2-hydroxypropyl)nitrosamine in rats, 313
354 Citrinin, tumorigenicity F344 rats, 279
of, in male
Dexamethasone, growth inhibition by, in vitro, and permanent cell culture lines of rat erythroleukemia, 205 Dimethyl amino substituents on aromatic organic compounds, cyclic amines as less mutagenic replacements for, and implications for carcinogenicity and toxicity, 263 Dimethylbenzanthracene induced and transplantable rat mammary tumors, failure of ascorbic acid to inhibit growth of, 67 7,12-Dirnethylbenx[a]anthracene-induced transformation of mammary cells in organ culture, seleniummediated dose-inhibition of, 187 1,2-Dimethylhydraxineand azoxymethane, inhibition of carcinogenicities of, by pyrazole, 147 Diphtheria toxin tesistance as marker, mutagenic activity of norharman and harman in Chinese hamster lung cells in assays with, 249 DNA repair synthesis, soluble and insoluble nickel compounds induce, in cultured mammalian cells, 271 DNA replication intermediate, formation of a new, in novobiocin-treated human melanoma cells, 51 Ehrlich ascites tumor, antitumor effect of palmitoleic acid on, 197 Embryo cells, hamster, promotional effect of different phorbol esters on morphological transformation of, 1 Embryo cells, hamster, role of fibronectin in the morphological transformation of, 9 Erythroleukemia, permanent cell culture lines of rat, and growth inhibition by dexamethasone in vitro, 205 Estrogen, effect of later treatment with, on reproductive tract lesions in neonatally estrogenized female mice, 115 Fecal flora and spontaneous liver tumorigenesis, effect of Konjac mannan on, in C3H/He male mice, 27 5-Fluorouracil, interferon potentiates cytotoxic effects of, on cell proliferation of established human cell
lines originating from neoplastic tissues, 239 Free radical scavengers, protection against hydroxyurea-induced cytotoxic effects in L5178Y cells by, 223 Gastric tumorigenesis, promoting effect of intestinal Pseudomonas aeruginosa on, in rats, with N-methyl-N’- nitronitrosoguanidine, 347 Harman and norharman, mutagenic activity of, in Chinese hamster lung cells in assays with diphtheria toxin resistance as marker, 249 HeLa cells, measurement of the response of, towards the radiomimetic activity of 120tetradecanoyl phorbol-13acetate, 45 Hepatocyte-mediated production of sister cbromatid exchange in co-cultured cells by acrylonitrile : evidence for extra cellular transport of a stable reactive intermediate, 213 Herpes a-transformed cell-induced tumors, modification of in mice fed different sources of protein, fat and carbohydrate, 161 Hodgkin lymphoma patients, correlation of substance(s) immunologically crossreactive with insulin, glucose and growth hormone in, 81 Human tumor cells, mutagenic virus replication in, 141 Hydrazine sulphate, and isoniazid, effect of antioxidants and antitoxicants of isoniazid on the formation of lung tumours in mice by, 75 N-bis( 2-Hydroxypropyl)nitrosamine, effects of lung and pleural carcinogenesis of, in rats, 313 Hydroxyurea-induced cytotoxic effects, protection against, in L5178Y cells by free radical scavengers, 223 Immune response, different weekly changes in, virus-transformed cellinjected mice fed two different diets, 175 Insulin, glucose and growth hormone, correlation of substance(s) immunologically cross-reactive with, in Hodgkin lymphoma patients, 81 Interferon potentiates cytotoxic effects
355 of 5fluorouracil on cell proliferation of established human cell lines originating from neoplastic tissues, 239 Isoniazid, effect of antitoxidants and antitoxicants of, on the formation of lung tumours in mice by isoniazid and hydrazine sulphate, 75 Konjac mannan, effect of, on spontaneous liver tumorigenesis and fecal flora in C3H/He male mice, 27 Lentinus edodes mycelia, anticarcinogenie actions of water-soluble and alcohol-insoluble fractions from culture medium of, 109 Liver tumorigenesis, spontaneous, effect of Konjac mannan on, and on fecal flora in C3H/He male mice, 27 Lung and pleural carcinogenesis of N-bis( P-hydroxypropyl)-nitrosamine in rats, effects of chrysotile asbestos on, 313 Lung neoplasia, chemically-induced, diminution of, in mice by phenobarbital pre-treatment, 33 Lymphoblastic leukemia, acute, low constitutive activity of aryl hydrocarbon hydroxylase in phytohaemoagglutinin-stimulated peripheral blood mononuclear cells of children after treatment for, 95 Mammary cell line, human, T-47D, expression of a mouse mammary tumor virus cross-reacting antigen on the cell surface of, 37 Mammary cells in organ culture, selenium mediated dose-inhibition of 7,12-dimethylbenz [ a ] anthracene-induced transformation of, 187 Mammary tumor virus, mouse, crossreacting antigen, expression of on the cell surface of T-47D, a human mammary cell line, 37 Metastatic heterogeneity, regional emergence of, in a growing tumor, 153 3’-Methyl-4-dimethylaminoazobenzene or 4-aminoazobenzene induction of tumors in transplacental or neonatal mice administered, 321 N-Methyl-N’nitro-N-nitrosoguanidine, promoting effect of intestinal Pseudo. monas aeruginosa of gastric tumorigenesis in rats with, 347
4-(Methylnitrosamino)-l-( 3-pyridyl)-lbutanone, the tobacco-specific carcinogen, or the formation of, during smoking, 3 39 Micronucleated cells, elevated frequency of, in the buccal mucosa of individuals at high risk for oral cancer: betel quid chewers, 125 Mitogenic stimuli, enhancement of, by phosphatidylinositol, 257 Monoclonal antibody for identification of human duct cell carcinoma of pancreas, 217 Morphological transformation of hamster embryo cells, promotional effect of different phorbol esters on, 1 Morphological transformation of hamster embryo cells, role of plasma fibronectin in the, 9 Mutagenic virus replication in human tumor cells, 141 Neonatally estrogenized female mice, effect of later treatment with estrogen on reproductive tract lesions in, 115 Neonates, response of mature mice to challenge with neuroblastoma after inoculation with neuroblastoma cells as, 229 Neoplastic tissues, interferon potentiates cytotoxic effects of 5-fluorouracil on cell proliferation of established human cell lines originating from, 239 Neuroblsstoma cells,human,prostaglandin D, inhibits the proliferation of, 287 Neuroblastoma, response of mature mice to challenge with, after inoculation with neuroblastoma cells as neonates, 229 Nickel compounds, soluble and insoluble, induce DNA repair synthesis in cultured mammalian cells, 271 Nicotinamide methyltransferase inhibition by S-adenosylethionine, 293 Nitrosomorpholine, carcinogenic effect of, administered in the drinking water to Sy,rian golden hamsters, 333 Norharman and harman, mutagenic activity of, in Chinese hamster lung cells in assays with diphtheria toxin resistance as marker, 249 Novobiocin-treated human melanoma cells, formation of a new DNA replication intermediate in, 51
356 Oral cancer, individuals at high risk for, elevated frequency of micronucleated cells in the buccal mucosa of betel quid chewers, 125 Ornithine decarboxylase enzyme activity in human and hamster pancreatic tumor cell lines, 87 Palmitoleic acid, antitumor effect of, on Ehrlich ascites tumor, 197 Pancreas, monoclonal antibody for identification of human duct cell carcinoma of, 217 Pancreatic tumor cell lines, hamster and human, ornithine decarboxylase enzyme activity in, 87 Phenobarbital pre-treatment, diminution of chemically-induced lung neoplasia in mice by, 33 Phorbol esters, promotional effect of different, on morphological transformation of hamster embryo cells, 1 Phosphatidylinositol, enhancement of mitogenic stimuli by, 257 Phytohaemoagglutinin-stimulated peripheral blood mononuclear cells of children after treatment for acute lymphoblastic leukemia, low constitutive activity of aryl hydrocarbon hydroxylase in, 95 Plasma fibronectin, role of, in the morphological transformation of hamster embryo cells, 9 Polycyclic aromatic hydrocarbons, determination of exposure to, by analysis of human urine, 301 Prostaglandin D, inhibits the proliferation of human neuroblastoma cells, 287 Pseudomonas aeruginosa, intestinal, promoting effect of, on gastric tumorigenesis in rata with N-methyl-N’nitroN-nitrosoguanidine, 347 Pyrazole, inhibition of carcinogenicities of 1,2dimethylhydrazine and azoxymethane by, 147 Pyrrolizidine alkaloid metabolites and analogues, carcinogenicity of, 61 Radiomimetic activity of 12-O-tetradecanoylphorbol-13-acetate, measurement of the response of HeLa cells towards the, 45 Reproductive tract lesions, effect of later
treatment with estrogen on, in neonatally estrogenized female mice, 115 Selenium-mediated dose-inhibition of 7,12-dimethylbenz[a]anthraceneinduced transformation of mammary cells in organ culture, 187 Sister chromatid exchange, hepatocytemediated production of, in co-cultured cells by acrylonitrile : evidence for extra cellular transport of a stable reactive intermediate, 213 12-O-Tetradecanoylphorbol-13-acetate, measurement of the response of HeLa cells towards the radiomimetic activity of, 45 Tobacco-specific carcinogen, 4-(methylnitrosamino)-l-( 3-pyridyl)-1-butanone, on the formation of, during smoking, 333 Transplacental or neonatal mice administered 3’-methyl-4-dimethylaminoazobenzene or I-aminoazobenzene, induction of tumors in, 321 Transplantable and dimethylbenzanthracene induced rat mammary tumors, failure of ascorbic acid to inhibit growth of, 67 Tryptophan pyrolysis products, induction of bladder cancer in mice by implanting pellets containing, 101 Tumor, growing, regional emergence of metastatic heterogeneity in, 153 Tumors, herpes 2-transformed cellinduced, modification of, in mice fed different sources of protein, fat and carbohydrate, 161 Tumorigenicity of citrinin in male F344 rats, 279 Tumor-promoting and biologically inactive phorbol esters, binding of, to artificial membranes, 135 Urine, human, determination of exposure to polycyclic aromatic hydrocarbons by analysis of, 301 Virus replication, mutagenic, in human tumor cells, 141 Virus-transformed cell-injected mice fed two different diets, different weekly changes in immune response in, 175
353
SUBJECT INDEX Volume 17 Acrylonitrile, hepatocyte-mediated production of sister chromatid exchange in co-cultured cells by, - evidence for extra cellular transport of a stable intermediate, 213 S-Adenosylethionine, nicotinamide methyltransferase inhibition by, 293 Adriamycin, apparent ineffectiveness of, for growth of androgen-dependent Shionogi carcinoma 115 in the mouse, 327 Aggregation, calcium-dependent and calcium-independent, of established and malignant cell lines, 19 Amines, cyclic, as less mutagenic replacements for dimethyl amino substituents on aromatic organic compounds: implications for carcinogenicity and toxicity, 263 4-Aminoazobenzene or 3’-methyl-4dimethylaminoazobenzene, induction of tumors in transplacental or neonatal mice administered, 321 Androgendependent Shionogi carcinoma 115, apparent ineffectiveness of adriamycin for growth of, in the mouse, 327 Anticarcinogenic actions of water-soluble and alcohol-insoluble fractions from culture medium of Lentinus edodes mycelia, 109 Antioxidants and antitoxicants of isoniazid, effect of, on the formation of. lung tumours in mice by isoniazid and hydrazine sulphate, 75 Antitumor effect of palmitoleic acid on Ehrlich ascites tumor, 197 Aromatic organic compounds, cyclic amines as less mutagenic replacements for dimethyl amino substituents on, and implications for carcinogenicity and toxicity, 263 Artificial membranes, binding of tumorpromoting and biologically inactive phorbol esters, 135 Aryl hydrocarbon hydroxylase, low con-
stitutive activity of, in phytohaemoagglutinin-stimulated peripheral blood mononuclear cells of children after treatment for acute lymphoblastic leukemia, 95 Ascorbic acid, failure of, to inhibit growth of transplantable and dimethylbenzanthracene induced rat mammary tumors, 67 Azoxymethane and 1,2-dimethylhydrazine, inhibition of carcinogenicities of, by pyrazole, 147 Beta1 quid chewers, individuals at high risk for oral cancer, elevated frequency of micronucleated cells in the buccal , mucosa of, 125 Biologically inactive and tumor-promoting phorbol esters, binding of, to artificial membranes, 135 Bladder cancer, induction of, in mice, by implanting pellets containing tryptophan pyrolysis products, 101 Buccal mucosa, elevated frequency of micronucleated cells in the, of individuals at high risk: beta1 quid chewers, 125 C3H/He male mice, effect of Konjac mannan on spontaneous liver tumorigenesis and fecal flora in, 27 Calcium-dependent and calcium-independent aggregation of established and malignant cell lines, 19 Carcinogenicities of 1,2_dimethylhydrazine and azoxymethane, inhibition of, by pyrazole, 147 Carcinogenicity of some pyrrolic pyrrolizidine alkaloid metabolites and analogues, 6 1 Cell lines, established and malignant, calcium-dependent and calciumindependent aggregation of, 19 Chrysotile asbestos, effects of, on lung and pleural carcinogenesis of N-bis(2-hydroxypropyl)nitrosamine in rats, 313
354 Citrinin, tumorigenicity F344 rats, 279
of, in male
Dexamethasone, growth inhibition by, in vitro, and permanent cell culture lines of rat erythroleukemia, 205 Dimethyl amino substituents on aromatic organic compounds, cyclic amines as less mutagenic replacements for, and implications for carcinogenicity and toxicity, 263 Dimethylbenzanthracene induced and transplantable rat mammary tumors, failure of ascorbic acid to inhibit growth of, 67 7,12-Dirnethylbenx[a]anthracene-induced transformation of mammary cells in organ culture, seleniummediated dose-inhibition of, 187 1,2-Dimethylhydraxineand azoxymethane, inhibition of carcinogenicities of, by pyrazole, 147 Diphtheria toxin tesistance as marker, mutagenic activity of norharman and harman in Chinese hamster lung cells in assays with, 249 DNA repair synthesis, soluble and insoluble nickel compounds induce, in cultured mammalian cells, 271 DNA replication intermediate, formation of a new, in novobiocin-treated human melanoma cells, 51 Ehrlich ascites tumor, antitumor effect of palmitoleic acid on, 197 Embryo cells, hamster, promotional effect of different phorbol esters on morphological transformation of, 1 Embryo cells, hamster, role of fibronectin in the morphological transformation of, 9 Erythroleukemia, permanent cell culture lines of rat, and growth inhibition by dexamethasone in vitro, 205 Estrogen, effect of later treatment with, on reproductive tract lesions in neonatally estrogenized female mice, 115 Fecal flora and spontaneous liver tumorigenesis, effect of Konjac mannan on, in C3H/He male mice, 27 5-Fluorouracil, interferon potentiates cytotoxic effects of, on cell proliferation of established human cell
lines originating from neoplastic tissues, 239 Free radical scavengers, protection against hydroxyurea-induced cytotoxic effects in L5178Y cells by, 223 Gastric tumorigenesis, promoting effect of intestinal Pseudomonas aeruginosa on, in rats, with N-methyl-N’- nitronitrosoguanidine, 347 Harman and norharman, mutagenic activity of, in Chinese hamster lung cells in assays with diphtheria toxin resistance as marker, 249 HeLa cells, measurement of the response of, towards the radiomimetic activity of 120tetradecanoyl phorbol-13acetate, 45 Hepatocyte-mediated production of sister cbromatid exchange in co-cultured cells by acrylonitrile : evidence for extra cellular transport of a stable reactive intermediate, 213 Herpes a-transformed cell-induced tumors, modification of in mice fed different sources of protein, fat and carbohydrate, 161 Hodgkin lymphoma patients, correlation of substance(s) immunologically crossreactive with insulin, glucose and growth hormone in, 81 Human tumor cells, mutagenic virus replication in, 141 Hydrazine sulphate, and isoniazid, effect of antioxidants and antitoxicants of isoniazid on the formation of lung tumours in mice by, 75 N-bis( 2-Hydroxypropyl)nitrosamine, effects of lung and pleural carcinogenesis of, in rats, 313 Hydroxyurea-induced cytotoxic effects, protection against, in L5178Y cells by free radical scavengers, 223 Immune response, different weekly changes in, virus-transformed cellinjected mice fed two different diets, 175 Insulin, glucose and growth hormone, correlation of substance(s) immunologically cross-reactive with, in Hodgkin lymphoma patients, 81 Interferon potentiates cytotoxic effects
355 of 5fluorouracil on cell proliferation of established human cell lines originating from neoplastic tissues, 239 Isoniazid, effect of antitoxidants and antitoxicants of, on the formation of lung tumours in mice by isoniazid and hydrazine sulphate, 75 Konjac mannan, effect of, on spontaneous liver tumorigenesis and fecal flora in C3H/He male mice, 27 Lentinus edodes mycelia, anticarcinogenie actions of water-soluble and alcohol-insoluble fractions from culture medium of, 109 Liver tumorigenesis, spontaneous, effect of Konjac mannan on, and on fecal flora in C3H/He male mice, 27 Lung and pleural carcinogenesis of N-bis( P-hydroxypropyl)-nitrosamine in rats, effects of chrysotile asbestos on, 313 Lung neoplasia, chemically-induced, diminution of, in mice by phenobarbital pre-treatment, 33 Lymphoblastic leukemia, acute, low constitutive activity of aryl hydrocarbon hydroxylase in phytohaemoagglutinin-stimulated peripheral blood mononuclear cells of children after treatment for, 95 Mammary cell line, human, T-47D, expression of a mouse mammary tumor virus cross-reacting antigen on the cell surface of, 37 Mammary cells in organ culture, selenium mediated dose-inhibition of 7,12-dimethylbenz [ a ] anthracene-induced transformation of, 187 Mammary tumor virus, mouse, crossreacting antigen, expression of on the cell surface of T-47D, a human mammary cell line, 37 Metastatic heterogeneity, regional emergence of, in a growing tumor, 153 3’-Methyl-4-dimethylaminoazobenzene or 4-aminoazobenzene induction of tumors in transplacental or neonatal mice administered, 321 N-Methyl-N’nitro-N-nitrosoguanidine, promoting effect of intestinal Pseudo. monas aeruginosa of gastric tumorigenesis in rats with, 347
4-(Methylnitrosamino)-l-( 3-pyridyl)-lbutanone, the tobacco-specific carcinogen, or the formation of, during smoking, 3 39 Micronucleated cells, elevated frequency of, in the buccal mucosa of individuals at high risk for oral cancer: betel quid chewers, 125 Mitogenic stimuli, enhancement of, by phosphatidylinositol, 257 Monoclonal antibody for identification of human duct cell carcinoma of pancreas, 217 Morphological transformation of hamster embryo cells, promotional effect of different phorbol esters on, 1 Morphological transformation of hamster embryo cells, role of plasma fibronectin in the, 9 Mutagenic virus replication in human tumor cells, 141 Neonatally estrogenized female mice, effect of later treatment with estrogen on reproductive tract lesions in, 115 Neonates, response of mature mice to challenge with neuroblastoma after inoculation with neuroblastoma cells as, 229 Neoplastic tissues, interferon potentiates cytotoxic effects of 5-fluorouracil on cell proliferation of established human cell lines originating from, 239 Neuroblsstoma cells,human,prostaglandin D, inhibits the proliferation of, 287 Neuroblastoma, response of mature mice to challenge with, after inoculation with neuroblastoma cells as neonates, 229 Nickel compounds, soluble and insoluble, induce DNA repair synthesis in cultured mammalian cells, 271 Nicotinamide methyltransferase inhibition by S-adenosylethionine, 293 Nitrosomorpholine, carcinogenic effect of, administered in the drinking water to Sy,rian golden hamsters, 333 Norharman and harman, mutagenic activity of, in Chinese hamster lung cells in assays with diphtheria toxin resistance as marker, 249 Novobiocin-treated human melanoma cells, formation of a new DNA replication intermediate in, 51
356 Oral cancer, individuals at high risk for, elevated frequency of micronucleated cells in the buccal mucosa of betel quid chewers, 125 Ornithine decarboxylase enzyme activity in human and hamster pancreatic tumor cell lines, 87 Palmitoleic acid, antitumor effect of, on Ehrlich ascites tumor, 197 Pancreas, monoclonal antibody for identification of human duct cell carcinoma of, 217 Pancreatic tumor cell lines, hamster and human, ornithine decarboxylase enzyme activity in, 87 Phenobarbital pre-treatment, diminution of chemically-induced lung neoplasia in mice by, 33 Phorbol esters, promotional effect of different, on morphological transformation of hamster embryo cells, 1 Phosphatidylinositol, enhancement of mitogenic stimuli by, 257 Phytohaemoagglutinin-stimulated peripheral blood mononuclear cells of children after treatment for acute lymphoblastic leukemia, low constitutive activity of aryl hydrocarbon hydroxylase in, 95 Plasma fibronectin, role of, in the morphological transformation of hamster embryo cells, 9 Polycyclic aromatic hydrocarbons, determination of exposure to, by analysis of human urine, 301 Prostaglandin D, inhibits the proliferation of human neuroblastoma cells, 287 Pseudomonas aeruginosa, intestinal, promoting effect of, on gastric tumorigenesis in rata with N-methyl-N’nitroN-nitrosoguanidine, 347 Pyrazole, inhibition of carcinogenicities of 1,2dimethylhydrazine and azoxymethane by, 147 Pyrrolizidine alkaloid metabolites and analogues, carcinogenicity of, 61 Radiomimetic activity of 12-O-tetradecanoylphorbol-13-acetate, measurement of the response of HeLa cells towards the, 45 Reproductive tract lesions, effect of later
treatment with estrogen on, in neonatally estrogenized female mice, 115 Selenium-mediated dose-inhibition of 7,12-dimethylbenz[a]anthraceneinduced transformation of mammary cells in organ culture, 187 Sister chromatid exchange, hepatocytemediated production of, in co-cultured cells by acrylonitrile : evidence for extra cellular transport of a stable reactive intermediate, 213 12-O-Tetradecanoylphorbol-13-acetate, measurement of the response of HeLa cells towards the radiomimetic activity of, 45 Tobacco-specific carcinogen, 4-(methylnitrosamino)-l-( 3-pyridyl)-1-butanone, on the formation of, during smoking, 333 Transplacental or neonatal mice administered 3’-methyl-4-dimethylaminoazobenzene or I-aminoazobenzene, induction of tumors in, 321 Transplantable and dimethylbenzanthracene induced rat mammary tumors, failure of ascorbic acid to inhibit growth of, 67 Tryptophan pyrolysis products, induction of bladder cancer in mice by implanting pellets containing, 101 Tumor, growing, regional emergence of metastatic heterogeneity in, 153 Tumors, herpes 2-transformed cellinduced, modification of, in mice fed different sources of protein, fat and carbohydrate, 161 Tumorigenicity of citrinin in male F344 rats, 279 Tumor-promoting and biologically inactive phorbol esters, binding of, to artificial membranes, 135 Urine, human, determination of exposure to polycyclic aromatic hydrocarbons by analysis of, 301 Virus replication, mutagenic, in human tumor cells, 141 Virus-transformed cell-injected mice fed two different diets, different weekly changes in immune response in, 175