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Synthetic organic chemistry. By Romeo B. Wagner and Harry D. Zook. John Wiley & Sons, Inc., New York, 1953. 15.5 × 23.5 cm. xii + 885 pp. Price $11.50
Book Notices Organic Reactions. Vol. V I I . ROGER ADAMS, Editor-in-Chief. John Wiley & Sons, Inc., New York and London, 1953. vii 440 pp. 16 x 23.5 cm. Price $9. This book is the seventh volume of a series started in 1942, and designed t o provide a compilation of all the more important synthetic chemical reactions. As in previous volumes, each chapter is written by an author who has had special experience with the reaction about which he is writing. The reactions covered in this volume include the Pechmann Reaction, the Skraup Synthesis of Quinolines, Carbon-Carbon Alkylations with Amines and Ammonium Salts, the von Braun Cyanogen Bromide Reaction, Hydrogenolysis of Benzyl Groups attached t o Oxygen, Nitrogen, or Sulfur; the Nitrosation of Aliphatic Carbon Atoms, and Epoxidation and Hydroxylation of Ethylenic Compounds with Organic Peracids. Each chapter in the series presents a comprehensive survey of the reaction under consideration. The survey includes a general discussion of method, modifications, examples of applicability, special precautions, a detailed description of the procedure. expected yields, and other pertinent data. Tables are included in each chapter listing compounds which have been prepared by or subjected to the reaction under discussion in that chapter. Among the contributors to Volume VII of Organic Reactions are Walter H. Hartung, Professor of Pharmaceutical Chemistry in the College of Pharmacy a t the University of North Carolina, and Robert Simonoff, of the William R. Rorer Co., Inc., who furnished the chapter on the hydrogenolysis of benzyl groups attached to oxygen, nitrogen, or sulfur. The entire book is thoroughly documented with references t o the original literature and is provided with a satisfactory index. The book should be of special interest to anyone engaged in research involving the syntheses of organic compounds.
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Essentials of Physiological Chemistry. 4th ed. By ARTHURK. ANDERSON.John Wiley &Sons, Inc.. New York, (Chapman and Hall, Ltd., London), 1953. vii 480 pp. 15.5 x 23.5 cm. Price $5. This book by Arthur K. Anderson, who is Professor of Physiological Chemistry a t the Pennsylvania State College, is now in its fourth edition, the first edition having been published in 1935. The book is designed to present the more important facts of biochemistry as related t o the animal body in a form which will be understandable t o the student with only a limited preparation in chemistry and biochemistry, and is designed especially for undergraduate students in biochemistry, home economics, premedicine, chemistry, bacteriology, and agriculture. M a n y advances which have occurred since the appearance of the t h u d edition in 1947 will be found in the new edition. Among some of the more important changes are the inclusion of a section on isotopes in the chapter on biophysical chemistry;
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an expansion of the chapter on lipids and antioxidants; and more or less completely rewritten chapters on enzymes and carbohydrate metabolism including recent developments. The subject of chemotherapy and adrenal hormones has been thoroughly revised, and in the chapter on vitamins more emphasis than heretofore has been placed on their physiological action.
Synthetic Organic Chemistry. By ROMEO B. WAGNERand HARRYD. ZOOK. John Wiley & Sons, Inc., New York, 1953. 15.5 x 23.5 cm. xii 885 pp. Price $11.50. In this book methods of organic syntheses most frequently employed in the preparation of monoand di-functional compounds are summarized. The methods described are collected in chapters each of which covers the formation of compounds containing a particular functional group or related groups. No attempt has been made to present detailed discussions, but references to the original literature and to other books and review articles are given for the better preparative procedures. The text is supplemented by tables of additional references and other examples which constitute a convenient index t o the literature relating t o the preparation of starting materials of relatively simple structure. I n compiling Synthetic Organic Chemistry, the authors have reviewed the more important books and journals relating t o organic syntheses which were published between 1918 and 1951. The book is provided with an index which is exceptionally complete and which emphasizes particularly the reactions of organic compounds. I t is quite unusual for any book t o include so much information in a relatively small amount of space. The compounds are classified according to functional groups and are arranged according to their carbon content into aliphatic, alicyclic, aromatic, and heterocyclic series. The book deserves wide acceptance by all who are interested in synthetic organic chemistry, either from a general or pharmaceutical viewpoint.
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Condensed Pyridazine and Pyrazine Rings (Cinnolines, Phthalazines, and Quinoxalines). By J. C. E. SIMPSON. Interscience Publishers, Inc.. New 394 pp. 16.5 x 24 cm. Price York, 1953. xvi 812.50. (Subscription Price $11.25). This is the fifth volume of a series of monographs covering heterocyclic chemistry in a comprehensive manner. I n this, as in the earlier volumes, the significance and interrelations of the various compounds are stressed. In the fifth volume the subject matter is presented in three sections: ( 1 ) the cinnolines, (2) the phthalazines. and (3) the quinoxalines. The first two groups are formed by the condensation of a pyridazine nucleus with an aromatic ring and the third by the fusion of a pyrazine with an aromatic ring.
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Essentials of Physiological Chemistry. 4th ed. By ARTHURK. ANDERSON.John Wiley &Sons, Inc.. New York, (Chapman and Hall, Ltd., London), 1953. vii 480 pp. 15.5 x 23.5 cm. Price $5. This book by Arthur K. Anderson, who is Professor of Physiological Chemistry a t the Pennsylvania State College, is now in its fourth edition, the first edition having been published in 1935. The book is designed to present the more important facts of biochemistry as related t o the animal body in a form which will be understandable t o the student with only a limited preparation in chemistry and biochemistry, and is designed especially for undergraduate students in biochemistry, home economics, premedicine, chemistry, bacteriology, and agriculture. M a n y advances which have occurred since the appearance of the t h u d edition in 1947 will be found in the new edition. Among some of the more important changes are the inclusion of a section on isotopes in the chapter on biophysical chemistry;
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an expansion of the chapter on lipids and antioxidants; and more or less completely rewritten chapters on enzymes and carbohydrate metabolism including recent developments. The subject of chemotherapy and adrenal hormones has been thoroughly revised, and in the chapter on vitamins more emphasis than heretofore has been placed on their physiological action.
Synthetic Organic Chemistry. By ROMEO B. WAGNERand HARRYD. ZOOK. John Wiley & Sons, Inc., New York, 1953. 15.5 x 23.5 cm. xii 885 pp. Price $11.50. In this book methods of organic syntheses most frequently employed in the preparation of monoand di-functional compounds are summarized. The methods described are collected in chapters each of which covers the formation of compounds containing a particular functional group or related groups. No attempt has been made to present detailed discussions, but references to the original literature and to other books and review articles are given for the better preparative procedures. The text is supplemented by tables of additional references and other examples which constitute a convenient index t o the literature relating t o the preparation of starting materials of relatively simple structure. I n compiling Synthetic Organic Chemistry, the authors have reviewed the more important books and journals relating t o organic syntheses which were published between 1918 and 1951. The book is provided with an index which is exceptionally complete and which emphasizes particularly the reactions of organic compounds. I t is quite unusual for any book t o include so much information in a relatively small amount of space. The compounds are classified according to functional groups and are arranged according to their carbon content into aliphatic, alicyclic, aromatic, and heterocyclic series. The book deserves wide acceptance by all who are interested in synthetic organic chemistry, either from a general or pharmaceutical viewpoint.
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Condensed Pyridazine and Pyrazine Rings (Cinnolines, Phthalazines, and Quinoxalines). By J. C. E. SIMPSON. Interscience Publishers, Inc.. New 394 pp. 16.5 x 24 cm. Price York, 1953. xvi 812.50. (Subscription Price $11.25). This is the fifth volume of a series of monographs covering heterocyclic chemistry in a comprehensive manner. I n this, as in the earlier volumes, the significance and interrelations of the various compounds are stressed. In the fifth volume the subject matter is presented in three sections: ( 1 ) the cinnolines, (2) the phthalazines. and (3) the quinoxalines. The first two groups are formed by the condensation of a pyridazine nucleus with an aromatic ring and the third by the fusion of a pyrazine with an aromatic ring.
506
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