JOURNAL OF THE
AMERICAN PHARMACEUTICAL ASSOCIATION Vol. XLIV, NO. 10
Technique of Organic Chemistry. Vol. 7. Edited by ARNOLDWEISSBERGER.Interscience Pub552 pp. lishers, Inc., New York. 1955. vii 16 x 24.75 cm. Price $8.50.
This book, which is the seventh in a series of nine volumes, presents extensive data on the physical properties and constants of organic solvents, much of the data being tabulated. The solvents are classified according t o chemical principles and are numbered for ready reference throughout the text. Inclusion of recent material in this reference volume is probably the reason Vol. VII in this series was delayed beyond the publication of Vol. VIII which 42,507( 1953). was reviewed in THISJOURNAL, The arrangement and text follows the style established in the first edition by A. Weissberger and E. S. Proskauer, and this second edition represents much revision of data by J. A. Riddick and E. E. Toops, Jr., of Commercial Solvents Corporation. The text is divided into sections under the headings: Classification of Solvents; Physical PropertiesDiscussion of Properties and Criteria for their SeTables lection ; Physical Properties-Tabulation, of Physical Constants; Criteria of Purity, Drying and Determination of Water; and Purification Methods. The extensive coverage of the text material is indicated by the 2,147 references arranged alphabetically a t the back of the book. There is also a general index and cumulative author and subject indexes for Volumes I to VIII. This volume as well as the others in this excellent series should definitely be available to graduate students and chemists in all fields.
Polarographic Techniques. By LOUISMEITES. Interscience Publishers, Inc., New York, 1955. 317 pp. 16 x 23.5 cm. Price $6. xiii
This book is intended to serve as an introduction to the field for students, practical analysts, and research chemists. The theoretical material included in the text was added t o explain and supplement the practical applications and experimental manipulations described. Complete and detailed directions for common manipulations involved in polarographic work to enable the beginner to avoid errors and unnecessary trials are given for a number of experiments. The text material is divided under the following section headings: The Nature and Scope of Polarographic Measurements ; Instrumentation ; The Polarographic Limiting Current; Theory of the Current-Voltage Curve; The Interpretation of Half-Wave Potential Data; Maxima and Their Suppression ; Techniques of Quantitative Polarographic Analysis; Amperometric Titrations ; and Special Techniques. Appendixes give information on “trouble shooting in polarographic circuits” and half-wave potentials, and diffusion current constants of inorganic substances. An extensive tabulation of the potentials and constants is included along with 307 literature references. Polarographic spectra are given on the front and back lining papers of the book where they can serve as convenient references. The type and format of the book are excellent, and a subject index is included.
This book should be a useful addition to libraries available to graduate students and to control and experimental analytical laboratories.
Origins of Resistance to Toxic Agents. Proceedings of the symposium held in Washington, D. C., March 25-27, 1954. M. G. SEVAG,ROGERD. Editors. Academic REID,and ORRE. REYNOLDS, 471 pp. Press, Inc., New York, 1955. xv 16 x 23.5 cm. Price $12.
The general basis for this symposium is a thorough exploration of available knowledge t o seek explanations for the development of resistance by microbial strains t o sulfonamides and other antibiotics. The concept formulated in this symposium is that the development of resistance to various toxic agents is associated with alterations and/or loss in enzyme proteins. The papers present material “. . . capable of benefiting physicians, biochemists, pharmacologists, entomologists, plant physiologists, students of cancer, and those who are interested in the theory of the evolution of living matter.” Twenty papers are given, and the resulting discussions are included. The material was presented at five sessions under the headings: resistance to microbicides; resistance to herbicides and insecticides; tolerance and addiction to drugs and alcoholism; resistance factors, infectious agents, and cancer cells ; and physiological, chemical, and genetic viewpoints. General author and subject indexes are appended.
College Physiology. By DONALDM. PACEand BENJAMINW. MCCASHLAND. Thomas Y. Cro615 pp. 16 x well Co., New York, 1955. xxi 23.5 cm. Price $5.50.
This excellently written and well illustrated text is intended to provide the foundation required by students interested in the various fields of zoology and it stresses particularly the functions of the human body. Discussions are clear and brief, developing the material for the beginning student. The clarity and brevity also make this a good quick reference book for basic points in physiology. The forty chapters are divided into eight parts under the headings: General; Structure and Movement; Nervous Coordination ; Receptors; The Transport System ; Respiration ; Nutrition and Elimination ; and Endocrine Glands and Reproduction. The book should be considered for use as a textbook by teachers of physiology in all college courses, including those in pharmacy schools.
Biochemistry and Physiology of Protozoa. Vol. 2. S. H. HUTNER and ANDRE LWOFF, Editors. Academic Press, Inc., New York, 1955. xiii 388 pp. 16 x 23.5 cm. Price $9.
This second volume, appearing four years after Volume I, presents much new information in the field of protozoology. The increased knowledge of culture methods and biochemical techniques have prepared the way for a greatly widened use of protozoa as biochemical tools. Pharmacists will be particularly interested in the chapter on “The Chemotherapy of Malaria, Piroplasmosis, Trypanosomiasis, and Leishmaniasis” by L. S. Goodwin and I. M. Rollo. The book is an excellent addition in