Twice monthly bibliography on prostaglandins — Early November prepared by Sheffield University, Biomedical Information Service, Sheffield S10 2TN

TWICE MONTHLY RIRLIOGRAPHY ON PKOSTAGLANDINS - EARLY NOVEMBER PKEPARED RY SHEFFLELD UNIVERSITY, BIOMEDICAL INFORMATION SERVICE, SHEFFIELD SlO ZTN

1. BOOKS, REVIEWS, SYMPOSIA Longenecker GL, Schaffer SW (Eds) Rurgrss Pub1 Co/Alpha Editions (Minneapolis), 1985, 352 pp ISBN 0 8087 5728 R Prostaglandins: ResearchamI Clinical Update Panchenko EP//Acad Med Sci USSR, Card101 Sci Ctr, Inst Prophylact Cardiol, Dept Ischem Heart Dis, Moscow, USSK KARDIOLOGIYA 1986, 26 (7) IO9 Angina pectoris - thromboxan-AZ, prostacyclin (Review) (Russian) 3. PROSTAGLANDINS E AND F Scheoo W. Steffen R. Schusdziarra V, Classen M//Tech Univ Munich, Klinikum Rechts Isar, Med Klin 2, Ismaninqer Str 22, D-8000 Munich 80, W Germany .J CLIN ENDOCRINOL METAB 19R6, 63 (4) 886 Calcium, calmodulin, and cyclic adenosine monophosphate modulate prostaglandin E2 release from isolated human gastric mucosal cells Yoshida M, Soejima H, Ueda S, Ikegami K//Kumamoto Univ, Sch Med, Dept Ural, l-l-l Honjo, Kumamoto 860, Japan NEPHRON 1986, 44 (2) 142 Role of renal "rostaglandin E2 in two-kidney, one-clip renovascular hypertension in rabbits Strasser RH, Benovic JL, Caron MG, Lefkowitz RJ*//*Howard Hughes Med Inst Dept Med Cardiol, Biochem & Physiol, Duke Univ Med Ctr, Durham, NC 27710, USA PROC NATL ACAD SC1 USA 1986, 83 (17) 6362-6366 Beta-agonist- and prostaglandin El-induced translocatio" of the beta-adrenevic receptor kinase: Evidence that the kinase may act on multiple adenylate cyclase-coupled receptors Lote CJ, Thewles A, Wilkins MR, Wood JA//Dept Physiol, Med Sch, Birmingham 815 ZTJ, England J PHYSIOL (LONDON) 1986, -378 (SI%'T) 34P Plasma-immunoreactive atrial natriuretic peptide (ANF) and urinary Pa2 excretion during vasopressin-induced natriuresis in the rat

Metabolic dehydration of prostaglanjin E2 ard cellular uptake of the dehydration product: Correlation with prostaglandin F&induced growth inhibition Kissing JP, Buxton TB//Vet kdm Med ctr, Infect Dis, Augusta, Ga 30910, USA J INFECT UIS 1986, 154 (4) 627 Effect of ibuprofen= gross pathology, bacterial count, and levels of prostaglandin E2 in experimental staphylococcal osteomyelitis Wuthrich RP, Vallotton MB//Univ Geneva, Hop Cantonal, Div Endocrinol, CH-1211 Geneva 4, Swirzerland AMER J PHYSIOL 1986, -251 (3) P2 F499 Proscaglandin E2 anl cyclic AMP response to vasopressin in renal medullary tubular cells Deliconstantinos G, Fotiou S//Univ Athens, Sch Med, Dept Exptl Physiol, GR-11527 Athens, Greece J ENDOCRINOL 1986, 110 (3) 395-404 Effect of prostqlandns E2 aid F2alph.a on membrane calcium binding, CaZ+/MgZ+-ATPase activity and membrane fluidity in rat myometrial plasma membranes Labussiere J, Ngui VE, Combaud JF// INRA, Traite Lab, 65 Rue St Brieuc, F-35042 Rennes, France REPROD NUTR DEVELOP 1986, 26 (4) 933 Effects of PGFZalpha prostaglandins on milk ejection in the ewe: consequences of ovariectomy with or without oestroproeestative supplementation (French) Lahera V, Duran F, Cachofeiro V, Canizo FJ, Tresguerres JAF, Rodriguez FJ//Univ Complutense Madrid, Fat Med, Dept Physiol, E-28040 Madrid, Spain PROSTAGLAND IEUK MED 1986, 24 (1) 35 Different excretion pattern of urinary PGE2 anj 6-keto-PGFlalpha in two kidney-one clip goldblstt rats Otani H, Sugimoto J, Morita M*// *Kansai Med Sch, Dept Phannacol, Moriguchi, Osaka 570, Japan PROSTAGLAND LEUK MED 1986, 24 (1) 51 Mobilization of intracellular calcium as a mechanism for the positive inotropic effect by prostaglardin FZalpha in isolated guinea pig atria

Feldberg W, Pyke DA, Stubbs WA//Nat1 Inst Med Res, London NW7 IAA, Englad J PHYSIOL (LONDON) 1986, -378 (SEPT) 81P Do drugs causing catalepsy on injection into the cerebral ventricles also cause hyperglycaemia in the cat?

Ylikorkala 0, Paatero H, Suhonen L, Viinikka L//Univ Helsinki, Dept Obstet & Gvnaecol, Haartmaninkatu 2, SF-00290 Helsinki 29, Finland BRIT J OBSTET GYNAECOL 1986, 93 (9) 950 Vaginal anl abdominal delivery increases maternal urinary 6-keto- prostaglandin Flalpha excretion

Ohno K, Fujiwara M, Fukushima M, Narumiya S*//*Kyoto Univ, Fat Med, Dept Pharmacol, Kyoto 606, Japan BIOCHPl BIOPHYS RES COMMUN 1986, -139 (2) 808

Williams WF, Osman AM, Shehata SW, Gross TS//Univ Marylald, Dept Anim Sci, College Pk, Md 20742, USA AND4 REPROD SC1 1986, ll_ (4) 237

t'enometer detection of prostqlandin FZalpha-induced luteolysis ard estrus in the Egyptian buftalo Krzymowski T, Carzocki J, Koziorowski M, Kotwicza J, Stefanczyk-Krzymwsk S//Univ Agr & Technol, Insc Anim Physiol, PL-10718 Olsztyn, Poland ANIM REPROD SC1 1986, 11 (4) 259 Counter current transfer of 3H-PGFZalpha in the mesometrium: a p3ssible mechanism for prevention of luteal regression 4. PRECURSORS Rokach J, Fiasimnons BJ, Adams J, Evans JF; Leblanc Y//Merck Frosst. Canada Inc, POB 1005, Pointe Claire, Quebec, Canada H9R 4P8 PHARMAOL RES IDMMUN 198618 (Aug)S, 11 The lipoxins: determination of their biosynthesis 5. Arachidonic Acid -I E. Hasselaar P. Akkerman JWN*//*Univ Hosp Utrecht, Dept Haematol, POB 16250, 3500 CG Utrecht, Netherlands BIOCHEM J 1986, 238 (3) 885-891 PAF-acether (1-O~,d,,yl/octadecyl-Zacetyl-sn-glycero-3- phsspbcholine)induced fibrinage" binding to platelets depends onmetabolic energy Kloprogze

Geuskens M, Naval J, Uriel J//Inst Rech Sci Cant, F-94802 Villejuif, France J CELL FHYSIOL 1986, 128 (3) 389 Ultrastructural studiesof the intracellular translocation of eniocytosed alpha-foetoprotein (AFP) by cytochemistry and of the uptake of 3Harachidonic acid bound to AFP by autoradiography in rat rhabdomyosarcoma cells Yu ACH, Chan PH*, Fishman RA//*lJ"iv Calif San Francisco, Sch Med, Dept Neural, Brain Edema Res Ctr, M-794, San Francisco, Ca 94143, USA J NEURCCHm 1986, 47 (4) 1181 Effects of arachidzic acid on glutamate ad gamma-aminobutyric acid uptake in primary cultures of rat cerebral cortical astrocytes ard narons Chabot MC, Chepenik KPt//*Thomas Jefferson Univ, Jefferson Med Coil, Daniel Baugh Inst Anat, 1020 Locust St, Philadelphia, Pa 19107, USA J CRANIOFAC GENET LEV BIOL 1986, -6 (3) 223 Cyclic AMP inhibits the release of prostaglanlins anl arachidonic acid from cultures of mouse embryo palate mesenchyme cells Judd A, Login I, Ehreth J, MacLeod R*//*Univ Virginia, Sch Med. Dept Med, Charlottesville, Va 22908, USA EUR J RIARMAO)L 1986, 128 (3) 151 Nafazatrcm, a" arachidzte metabolism inhibitor, decreases polactin ard GH release

Suekawa M, Yuasa K, Isono M, Sane H, Ikeya Y, Sakakibara I, AburadrlM, Hosoya E//Tsumura Res Insf Pharmacol, Iharaqi 30011, Japan FOLIA PHARMACOL JPN 1986 RR (4) 261 Pharmacoloqical studies engineer. IV. Effect of (6)-shogaol on the arachidonic cascade (Japanese) Dupont L, Germain G, Dideberg O//Unio Liege Sart Tilman, Inst Phys 85, Cristallor: Lab, B-4000 Liege, Belgium PHARMACOL RES WMMUN 1986" (Aug)S, 25 Crystal arkimolecular structure of BE: 52021, a PAF-acether antagonist. Comparison with the conformation of kadsurenone ard related compounds Snyder F, Blank ML, Johnson U, Lee T-c, Malone B, Robinson M, Woodard DS//Oak Ridge Assoc Llniv, Div Med 6 Hlth Sci, Oak Ridge, Tn 37831, USA PHARMACOL RES COMMUN 198618 (Aug)S, 33 Alkylacetyl~lvcerols versus lyso-PAF as precursors in PAF biosynthesis ati the role of arachidonic acid in PAF metabolism Baqgiolini M, Dewald R//Univ Bern, Theodor Kocher Inst, CH-3001 Rem, Switzerland PHARMACOL RES COMMUN 1986 fi (Aug)S, 51 Stimulus amplification bv PAF ati LTR4 in human neutrophils Bruynzeel PLB, Koerderman L, Kook PTM, Hameling ML, Verhagen J//State Univ Utrecht Hosp, Dept Pulm Dis, Catharijnesingel 101, 3511 CV Utrecht, Netherlands PHARMACOL RES COMMUN 1986 2 (Aug)S, 61 Platelet-activating factor (PAL;acether) itiuced leukotriene C4 formation ati luminol dependent chemiluminescence by human eosinophils Etienne A, Hecquet F, Soulard C, Touvay C,Clostre F, Braquet P//Inst Henri Reaufour, Res Labs, 72 Ave Trap, F-91940 Les Ulis, France PHARMACOL RES KIMMLIN 1986 - 18 (Au<)S,

Vilain I\,Lagencc V, Touvap C, tl~i,~ la S, Ration J, Lefort J, Braque~ P, Varp;aftig RB/ /Inst Henri Bcau10i.r. Ki, Labs, 17 Ave Descartes, F-Y? 351; Plessis Robinson, France PHARMACOL RES O)MMUN 1986 1X ,i,,i,,S, 119

F"er:hML, Khirnbadi HS, Kowles JR. Rraquet I',Kamwril PWllGeorgetown Univ, Med Ctr, Dept Surg, Div Tr~nsplantat, uashingtoo, DC 20007, IUS4 PHAKMACOL KES COMMUN 1986 18 (Aui:)S, 127 The causal role 01 PAY anl ieu<,,trienes in acute cardiac .illy:r,ifr rejection in rats Bussolin" F, Mreviario F, T~tta C, Aglietta M, Sanavio F, Mantovanl A, Dejana E*ll*Margio Negri Inst Pharmacol Res, V Eritrea 62, I-20157 Milan Italy PHARMACOL RES COMMUN 1986 -I8 (Aup)S. 133 Interleukin 1 stimulates platelet activating factor production in cultured human erdothelial celli Plante GE, Hebert RL, Lamoureux C, Braquet P, Sirois P//Univ Sherbrooke, Dept Physiol, Sherbrooke, Quebec, CanadaJlK 2Rl PHARMACOL RES COMMI'N1986 -18 (Auq)X, 173 Hemodynamic eftects rof PAF-acether Cwspo MS, Inarrea P, Nieto ML, Pernatxiez-Gallard" S//Fdn Jimenez Diaz, Inst Invest Med, Exptl Nephrol Lab, Madrid, Spain PHARMACOL RES COMMUN 198b" (Aug)S, 181 Evidence of a role for PAF-acether in the pathophysiology oi the shock state Adnot S, Lefort J, Lagente V, Btaquet P, Vargaftig BB//Inst Pasteur, INSERM, U285, Unite Vienins, 25 Rue Dr Roux, F-75724 Paris 15, France PHARMACOL

RES

O)MMUN 1986

‘a

(Aug)S,

71

197

The relative role of PAF-acether ard icosanoids in septic shock

Interference of EN 52021, a PAFacether antagonist, with erdotoxininduced hypotension in the guinea pig

Maes L, Andries R, Bourgain RH, Sraquet P//Vrije Univ Brussel, Fat Med, Dept Physiol, Iaarbeeklaan 103, B-1090 Brussels, Belgium PHARMACOL RES COMMUN 19Rhl8_ (Aug)S, 81 Endogenic PAF-acether production bv guinea pig endothelial cells in experimental arterial thrombosis

6. Lrukotrienes Stahl RAK//Univ Washington, Dept Med, Div Nephrot. KM II, Seattle, ~a 98145, I!SA KLItiWOCH0,2SCHK 1986, 6.4 ! 181 Hi $ Oie Bedeutung van Eicosanolden beI tlomcrularen Erkrankungen

Gvllenhammar H, Riqertz B, Becker W, Svensson J, Palmblad J//Sodersjukhuset, Karolinska Inst, Dept Med 3, S-10064 Stockholm, Sweden IMMUNOL IXTT 1986 13 (4) 185 Essential fatty acid deficiencv in rats: effects on arachidonate metabolism, generation of cyclooxygtnase products ard functional responses in neutrophils

Hiagdard H, tieiqvlsi 5, Iiuudcli., Venge P, Dahl K, Sonleqaard Ji/Unti Copenhagen, Bispzbjerg Hosp. Drp~ DetXla~"l, Bis~rzrbjer?; Bakke i 3, L/+00 Copenhagen NV, Dermark ALLERGY 1986, 41 (5) 365 Chevoractic xtivih. ot LTh+ i:imiin

TK, Yuun,: K, Lha,:pia>,, F, i:har,>ttr L. Denis 0. Ford-Hutchinson AW. Frenette R, Gauthier J-Y, Guirdon Y, Kakushima N, Mas.wn P, McFarlane C, Piechuta H, Kokach J, Zarnboni. R, DeHaven KN, %ycork 4, Porg SS//MET<% Fross~ Canala Inc, Dep: Pharmacol & Harczy M, Maclouf J, Pradelles P, ?ed Chem, PO8 IOU5 U"rv~l ) quebr,, Braquet P, Borgeat P, Sirois P//Univ Wallace JL, Whittle BJR//Wellcome Res “nnxla H9P 4P8 Sherbrooke, Fat Med, Dept Padiat, Labs, Dept Mediator Pharmacol, &ecken- LAN J FtiYSlOL R1AMAUIL i9dbh&_ (8) Sherbrooke, Quebec, Canada JlK 2Rl ham BK3 3BS, Kent, Englard IOh PHARMACOL RES COMFRJN1986 -18 (Aug)S, PROSTAGLANDINS 1986, 32 (1) 137 I.-64Y,Y23 sodiuni(be~z5**, gdmnu 111 Profile of gastrointe~inal damage Inhibitory effects of a novel platelet R*)-4-(j--(;-,,.~yl-3-tlydroxy-:!activating factor (PAF) antagonist (BN induced by plaLelet-activating:facto, propylphenoxy)prupylthio)-gd~,~-. hvdroxy-beta-metti)lbenez~nr!butano~tr, 52021) on antigen-induced prostaglandBourgain RH, Maes L, Andries K, d selective, orally active leukniriene in ard thromboxane formation by the guinea pig lung Braquet P//Vrije Univ Brussel, Fysiol receptor aritagvnist h Fysiopathol Lab, Laarbeeklaan 103, B-1090 Brussels, Belgium Jiiries

Touvay C, Vilain B, Etienne A, Clostre F, Braquet P//Inst Henri Beaufours, Res Labs, 72 Ave Trop, F-91940 Les Ulis, France PHARMACOL RES COMMUN 1986 -18 (Aug)S, 91 Comparative effects of drugs on leukotrienes-, PAF-acether-, and histamine-induced contractions of guinea pig lung parenchymal strips

Simonson MS, Dunn M.l*//*Univ Hosp Clewlard, Div Nephrol, Clewlard, Oh 44106, USA KIDNEY INT 1986, 30 (4) 524 Leukotriene C4 aid D4 contract rat glawrular mesargial cells 7. Prostacyclin Van Sickle WA. Wilcox HG. Nasiletti A//Univ Tennessee, Ctr ith Szi, Hlth Sci Ctr, Dept Pharmacol, Memphis, Tn 38163, USA BICCHEM BIOPHYS RES O)MMUN 1986, 139 (2) 416 i?&induced cardiac prostacyclin synthesis: relative contribution of HDL apoprotein ard lipid

Goldstein RE, Ezra D, Laurirdo FRM, Feuerstein GZ//Uniformed Serv Univ Hlth Sci, Dept Med d Pharmacol, Div Cardiol 6 Clin Pharmacol, Bethesda, Md 20814, USA PHARMACOL RES COMMUN 1986 -18 Metz B, Sim AD, Mccraw AP, Clelard (Aw:)S, 151 ME//Merckle QnbH, Dept Res & Coronary and pulmonary vascular effects of leukotrienes ard PAF-acether Dev, Chem Pharm Fabrik, Postfach 1161, D-7902 Blaubeuren, W Germany ARZNEIM-FORSCH-DRUG RES 1986 Doly M, Braquet P, Bonhomme B, 36-2 (9) 1363 Meyniel G//Fat Med & Pharm Clermont Effect of etofylline clofibrate Ferrand, Biophys Lab, BP 38, on experimental thrombus formation F-63001 Clermont Ferrald, France and prostacyclin activation PHARMACOL RES COMMUN 1986 -18 (Aug)S, 201 Cirino G, Sorrentino L//Univ Naples, Comparative effects of leukotrienes Dept Expel Pharmacol, Via Rodino 22, and PAF-acether electrophysiolcgical I-80138 Naples, Italy activity of the rat retina AGENT ACIION 1986 18 (5-6) 535 Phospholipase inhibitinn and prostacyRainsford KD//Univ Cambridge, Dept clin generation by gastric muscularis Pharmacol, Hills Rd, Cambridge, and mllcosa layers CB2 ZQD, England PHARMACOL RES COMMUN 1986 -18 Demolle D, Boeynaems JM//Univ Libre (Aug)S, 209 Bruxelles, Sch Med, Inst InterdiscipRelative roles of leukotrienes linary Res, B-1050 Brussels, Belgium and platelet acrivatiw factor PROSTAGLANDINS 1986, '2 (1) 155 in experimentally-irduced qastric Prostacyclin production by the bwine ulceration aortic smooth muscle Vincent JE, Zijlstra FJ, v d Broek Lewinski A, Pawlikowski M//Med Acad AMWC, Gezel TE//Erasmus Univ, Fat Lodz, Inst Endocrinol, Dept Exptl Med, Dept Pharmacol, POB 1738, Endocrinol 6 Hormone Diagnost, Dr 3000 Dr Rotterdem, Netherlards Sterling Str 3, PL-91425 Lodz, Poland PROSTAGLANDINS 1986, 21. (1) J PINEAL RES 1986, 2 (3) 285 132 Melatonin suppression of the colloid Opposite effects of adrenalectomy on eicosanoid release in rat peritoneal droplet formation in the thyroid is not related to the alteration of macrophages anl spleen prostacyclin synthesis Lecomte M, Nunez D, Boeynaems JM//Univ Libre Bruxelles, Sch Med, Inst Interdisciplinary Res, B-1050 Brussels, Belgium PROSTAGLANDINS 1986, 2 (1) 150 Covalenr bindilg of eicosanoids t" platelet proteins Ardaillou R, Baud L, Sraer J//Hop Tenon, INSEIP? 64. 4 Rue Chine, F-75970 Paris 20, France AMER J MF.D 1986, g (2B) 12 Leukotrienes ard other lipoxygenase products of arachidonic acid synthesized in the kidney Catella F, Nowak J, Fitzgerald GA*//*Vanderbilt Univ, Div Clin Pharmacol, Nashville, Tn 37232, IJSA AMER J MED 1986, g (ZB) 23 Heasurement of renal ard nowrenal eicosanoid synthesis

Burhop KE, Varrlerzee H, bizios K, Kaplan JE, Malik Ab*//*Union Univ Albany Med Coll, Dept Physiol, 47 New Scotlard Ave, Albany, NY 12208, USA AhER REV RESP DIS 1986, 134 (3) 548 Pulmonary vascular reswnse t" platelet-activatig factor in wake sheep and the role of cyclooxygenase metabelites

Sinzinger H, Kalliman J, Peskar BA//Vienna Univ, Dept Internal Med 2, Dept Cardiol, A-1010 Vienna, Austria PROSTAGLAND LEIJKMED 1986, 24 (1) 15 Prostacyclin synthesis stimxatirg plasma factor in coronary heart a

Isease

8. Thromboxanes Collier A, Tymkewycz P, Armstrom R, Young RJ, Jones RL, Clarke BF//Univ Edinburgh, Royal Infirm, Dept Diabet & Dietet, Edinburgh EH3 PYW, Midlothian, Scotland DIABETOLOGIA 1986, 29 (8) 471 Increased platelet xomboxane receptor sensitivity in diabetic patients with proliferative retinopathy

Metz SA//univ Colorado, Hlth Sci Ctr, Dept Med, Div Clin Pharmacol, C-237, 4200 E 9th Ave, Denver, Co 80262, USA J PHAFMACOL EXP THER 1986 238 (3) 819 Putative roles for lysop~~lipids as mediators ard lipoxygenase-mediatel metabolites of arachidonic acid as potentiators of stimulus-secretion coupliw - dual mechanisms of parahydroxymercuribenzoic acid-irduced insulin release Mansour S, Daniel E@//*McMaster Univ, Fat Hlth Sci, Dept Neurosci, 1200 Main St W, Hamilton, Ontario, Canala L8N 325 CAN J RiYSIOL R1A@tAWL 1986 64 (8) 1096 Maintenance of tone, role of arachid""ate metabolites ati effects of sensitization in guinea pig trachea Stewart AG, Piper P.J//Koyal Coil Surg Englad, Dept Phannacol, Lincolns Inn Fields, Lotion WC2A 3PN, Englad PHAIIMAU)L RES U)MMlJN1986 l&i (Aug)S, 163 Platelet-activatix factor-itiuced vascorstriction in rat isolatal perfused hearts: contribution of cycle-oxygenase ard lipoxygenase arachidonic acid netabolites 10. RELATED ENZYMES Littner MR, Kazmi GM, Lott FD//Vet Adm Med Ctr, Dept Med, lllP, 16111 Plumntzr St, Sepulveda, Ca 91343, USA J APPL FHYSIOL 1986, 61 (3) 988 Distribution of cvcloGy~enase products with cyclooxyeenase inhibition in isolated dog lung Feiters MC, Aasa R, Malmstran BG, Veldink GA*, Vliegenthart JFG//*State Univ Utrecht, Dept Biophys & Biochem, Padualaan 8, 3584 CH Utrecht, Netherlads BI~HIM BIOPHYS ACTA 1986, 873 (2) 182 Spectrcscupic studies on tkTnteractions between lipoxygenase-2 aid irs product hydraperoxides Aharony D, Stein RL//Dept Pharmacol, Pulmonary Sect, Stuart Pharmaceuc, Uiv ICI Americas Inc. Irilmigton, De 19897, USA J BIOL CHFM 1986, -261 (25) 11512 Kinetic mechanism of guinea pig neutrophil 5-lipoxygenase She" R-F, Tai H-H*//*Div Med Chem & Pharm, Co11 Pharm, Univ Kentucky, Lexixton, Ky 405360082, USA J BIOL CHEM 1986, 261 (25) 11592 -: Immunoaffinity purification ard characterization of th-cmboxane synthase fr an porcine lung

9, METABOLITES Wakayama EJ, Dillwith JW, Blanqtist GJ*//*Univ Nevada, Dept Biochem, Reno, NV 89557, USA INSECT BICCHEM 1986, 16 (6) 895 Occurrence ard metabolism of prostaglandins in the lnusefly, Musca domestica CL.)

Jeremy JY, Mikhailidis DP, Dandona P//Royal Free Hosp, Sch Ned, Dept Chen Path"1 S Human Metab, Merab Unit, Lordon NW3 2QG, Englanl DIABETES RES CLIN EXP 1986, i (6) 127 Stimulation bv qlucose and c
1

e.

Flcisher LN, ?Icc:ahan MCi /N Cart, ,iu,i state Univ, Sch Vet Ned, Dept Afiat Physiol Sci 6 Radial, 4700 Hiltsb?rough St, Raleigh, h;C 27606, USA CURR EYE RES 1986, 5 (9) 624 Time c"urse for prostagland in bvni!~enis bv rabbit tens during endotoxi~iirduced "crllar inflammation Otani H, Engelman RM, Rousou Ji, Rreyer RH, Das DK*//*Univ Connecticut, nept Surg, Farmington, Ct 06032, IJSA I "IOLCELL CARDIOL 1986, 18 (9) 953 Enhanced prostaglandin syzhesis due to phospholipid breakdown in ischemicreperlused myocardium

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Schl"nJorif D//Yeshiva Univ Alber: Einstein Co11 Med, Dept Med, Div Renal, Bronx, NY 10461, USA AMER J MEL, 1986, 81 (2B) 1 Renal prostaglard~~ synthesis: sites of production ard specific actions oL prostaglandins Cirillo R, et al//Univ Naples, Fat Med & Chirurg 2, Med Clin 1, Via Pansini 5, I-80131 Naples, Italy MED-RIV ENC MED ITAL 1986, 6 (2) 152 Pharmacological modulation of prostacyclin ard thromboxane synthesis by human heart in vitro (Italian)

Pogr CP, Morley J;/Saldoz ,.t<, h eclil? Res, a-4002 Basei, SwiLzerlaM PHARMAU,L RES (UMMUN lY8b 18 (Aua)S. ? 17 Evidence favouris PAt' rat.hei Lhan ieukotrienes in rhe pattoogcnrsi‘; "I astlmla

12. EFFECTS Lorenz JN, Welch WJ, Jackson RA, Rotchen TA, Ott CE//Univ Kentucky, Sch Med, Dept Physiol, Lexington, Ky 40536, USA PROC SOC EXP BIOL MED 1986, 183 (1) 59 Role of volume ard prostaglardin synthesis in the suppression of renin by saline in the rat

I.d&eman GEZ, Vesotc lb, kcrsmaekeis GM, Heiremans J, Haensch CF, Deroy G, Uyttenbroeck FL, Herman AG//Univ lnstellirp: Antwerp, St Camillus Hosp, Div Pharmacol, Univ Plein 1, E-2610 Wilrijk, Belgium BRITJ CANCER 1986, 54 (ij 4i! Prcstacyclin ati tkrzboxane in benyn ard rralignant breast turnours

Lihrmann 1, Drlarue C, Homo-Delarche F, Netchitailo P, Leboulel$-er F, Jaudry H//Univ Rouen, Haute Nonuaniie, "ac Sci, Rech Endocrinol Molec Grp, ZNRS, Unite 650, INSERM, F-76130 Mt St 4ignan, France 'ROSTAGIANDIES 1986, 32 (1) 127
(.illjam H, Strativik B, ElI.in A, Cjimari LG//Huddiwe Univ Hasp, Karolinska lnst, Dept Lnng Med. S-14186 Huddirggc, Sweden SCAND J CLIN WH IIWES'I I'+&, 46 (6, 511 Increased ilulr frstion d arachid "nit acid in bronchial pbsphotipids in patients with cystic fibrosis

)"rman RV, Schwartz MA, Terrian )M//Kent State Univ, Dept Biol Sci, :ent, Oh 44242, USA IRAIN RES BULL 1986, 17 (2) 243 'rostaglardin involvement in the E ,voked release of D-aspartate fro,, erebellar mossy fiber terminals

Boeynaems JM, 0emoile U, \dn Cowordrn A//Univ Libre Bruxelles, Sch Med, Lnst Interdisciplinary Kes, H-1050 Brussels, Belgium PROSTAGLANDI~ iYBb, 31 (I) 143 Prostacycli n-stimulatF% drugs: no*' prospects

Mjknailidis UP, Barralas HA, De souza .i ETS, O'Dell BL*//*Univ Missouri, V , JeremyJY, Wakelirg A, Dationa le!x Piorhen, 3~2-A Chem Bldg, Columbia, P//Royal Free Hasp, Sch Med, Dept Chem [c 65211, 'ISA Pathol & HumanMetab, Met&o1 Unit, NUT& 1986, -116 (8) 1448 Lordon, Englard iffect of zinc status on the binding PROSTAGIAND IEUK MED lY8b, 14 i,ljL; Comic M, Breton M, Colard O//CHU St mf prostaglanlins to ovarian membranes Adrenalin?i-irduced hyperqF%ability Antoine, 27 Rue Chaligny, F-75571 nd intact platelets of pregnant rats of platelets ard enhancel thznoboxane Paris 12, France release in anorexja nervosa PHAFMACOL RES OMMUN 1986 18 (Auq)S, 3. PROSTAGLANDINS IN MEDICLNE 43 elldvold E, Gottlieb C, Svanbom K, Bradlow BA et aL/Michael Reese Hoso & Acylation of 1-alkyl- arri l-acyl-lysoilljam H, Strardvik 8, Bygdeman M, Med Ctr, Chicago, 11 60616, USA phospholipids by rat platelets 1 neroth P//Karolinska Hosp. Dept N ENGL J aD 1986, -315 (14) 892 bstet & Gynecol, S-10401 Stockholm Haye-Legrard I, Duliost A, Vivier E, Platelet anl vascular 1 mction duriq 0, Sweden Roubin R, Benveniste J//Univ Paris fish-oil timiniswatioii (Letter) REPROD FERTIL 1986, 78 (1) 311-314 Sud, INSERM, U200, 32 rue Carnets, 4 bsence of prostaglald= in semen of F-92140 Clamart, France rn' en with cystic fibrosis is an indicatPHARMACOL RES COMMUN 19862 (Aug)S, 239

Heavey DJ, Kobsablack A, Barrow SE, Chappell CG, Greaves MU, Dollery CT//Seeley G Mudd Bldg, Roan 610, 250 Longwood Ave, Boston, Ma 02115, USA J ALLERG CLIN MMIJNOL 1986, 78 (3) Pt 1, 458 Prostaqlandin-DZ and histamine release in cold urticaria Badr KF, Kelley VE, Rennke HG, Brenner BM//Vanderbilt Univ, Med Ctr, Sch Med, Div Nephrol, B2214 Med Ctr N, Nashville, Tn 37232, USA KIDNEY INT 1986, 30 (4) 474 Roles for thrombo~ne A2 and leukotrienes in endotoxin-induced acute renal failure Makila UM, Jouppila P*, Kirkinen P, Viinikka L, Ylikorkala O//*U"iv Oulu, Dept Obstet & Gynecol, SF-90220 Oulu, Finland OBSTET GYNECOL 1986, 68 (4) 537 Placental thromboxane ard prostacyclin in the regulation of placental blood flow Makarainen L, Ylikorkala O//Univ Oulu, Dept Obstet & Gynaecol, SF-90220 Finland BRIT J OBSTET GYNAECOL 1986, 93 (9) 974 Primary and myoma-associated manorrhagia: role of prostaglandins ard effects of ibuprofen Martinezlavin M, Castillejos G//Inst Nacl Cardiol Ignacio Chavez, Rheumatol Serv, Mexico City 14080, DF, Mexico J RHEUMATOL 1986, 12 (4) 824 Ferritin and prostaglandins in hypertrophic osteoarthropathy - Reply (Letter) Matuccicerinic M//Univ Florence, Inst Med Clin 2, Chair Med Pathol 1, I-50121 Florence, Italy J RHEUMATOL 1986, 12 (4) 834 Ferritin ard prostaglandins in hypertrophic osteoarthropathy (Letter) Newhouse MT, Sears MR//McMaster Univ, Hamilton, Ontario, Canada LRS 4L8 N Z MED J 1986, 99 (808) 641 Platelet activatiq factor, ketotifen and asthma (Letter) Kondo T, Ogawa K*, Satake T, Kitasawa M, Taki K, Sugiyama S, Ozawa T// *Nagoya Univ, Fat Med, DEpt Biomed Chem, Tsuruma Cho 65, Showa ku, Nagoya, Aichi 466, Japan CLIN CARDIOL 1986, 9 (9) 413 Plasma-free eicosap~ntaenoic acid/ arachidonic acid ratio: a possible new coronary risk factor Stefanovic V, Ciric V//Univ Nis, Sch Med, Inst Nephrol, UL Brace Taskovica 48, YU-180000 Nis, Yugoslavia NUC COMPACT-COMP NEWS NUCL M 1986, l;r (4) 217 Thromboxane B2 formation in patients with acute myocardial infarction

Elevation of cyclic AMP by prostacyclin is accanpanied by relaxation of bovine coronary arteries and contraction of rabbit aortic rings

The hypoplastic left heart syndrome: evidence of preoperative myocardial and hepatic infarction in spite of prostaglandin therapy

Aksulu HE, Turker RK*//*Univ Ankara, Fat Med, Dept Pharmacol, Ankara, Turkey EUR J PHAFMACOL 1986, 128 (l-2) 67 Iloprost (ZK 36 374) prevents angiotensin I conversion in the isolated perfused rat lung against anoxia

Deakin M, Ramage J, Paul A, Gray SP, Billings J, Williams JG*//*Roval Naval Hosp, Dept Gastroenterol, Gosport PO12 2AA, Hants. Enslard GUT1986, 27 (19) 1054 Effect of Tnrcstil, a synthetic prostslandin-E2 on 24-hour intragastric acidity, nocturnal acid ani pepsin secretion

Heaslip RJ, Giesa FR, Rimele TJ, Grimes D//Ayerst Labs Res Inc, Vept Pharmacol, CN8000, Princeton, NJ 08543, USA EUR J PHAFMACOL 1986, 128 (l-2) 73 Sensitivity of the PGFZalpha -versus carbachol-contracted trachea to relaxation by salbutamol, forskolin and prenalterol Ertl G, Fiddler VB, Bauer B, Schwarzenberger P, Kochsiek K//Univ Wurzburg, Med Kli", Josef Schneider Str 2, D-8700 Wurzburg, W Germany J CARDIOVASC PHAFMAafL 1986, 5 (5) 1078 Effects of nifedipine and indomethacin on leukotriene C4- aml D4-induced coronary constriction at normal ard reduced coronary perfusion in dogs Mona S, Chi-Rosso G, Miller J, Hoffman K, Rasgaitis KA, Belder P, Crooke ST//SKhF Labs, Dept Molec Pharmacol, POB 7929, 1500 Spring Garden St, Philadelphia, Pa 19101, USA MOL PHAFMACOL 1986, 30 (3) 235 Leukotriene B4 irducz formation of inositol phosphates in rat peritoneal polymorpho"uclear leukocytes Munos NM, Shioya T, tirphy TM, Primack S, Dame C, Sanls MF, Leff Al//*Univ Chicago, Dept Med, Pulm & Crit Care Med Sect, 5841 S Maryland Ave, Chicago, II 60637, USA J APPL MIYSIOL 1986, 61 (3) 1173 Potentiation of vagal contractile response by tbranboxane mimetic U-46619 Maigaard S, Forma" A, Andersson KE//Aarhus Kommune Hasp, Dept Obstet 6 Gynecol, SK-8000 Aarhus C, Denmark ACIA PHYSIOL SCAND 1986, 128 (1) 33 Relaxant and contractile xects of some amines and prostanoids in myometrial and vascular smooth muscle within the human uteroplacental unit Yarringto" G, Fontwit K, Figueroa JP, Massman" A, Nathanielss PW//Yale Univ, Sch Med, Dept Epidemiol & Pub1 Hlth, Div Biostat, 333 Cedar St, New Haven, Ct 06510, USA YALE J BIOLMED 1986, 59 (4) 415 Reversal of the effectsof 4-aminoantipyrine on myometrial and cervical electraayographic activity by PGF2alpha in the ovariectomised estradiol-replaced "on-pregnant ewe

Moodie DS, Gill CC, Sterba R, Stewart 14. PROSTAGLANDINS AS DRUGS Vegesna RVK, Diamond J*//*Univ British R, Ratliff NB//Clevelard Clin Educ Fdn, Dept Cardiol, 9500 Euclid Ave, Columbia, Fat Pharmaceut Sci, Div Clevelard, Oh 44106, USA Pharmacol & Toxicol, 2146 E Mall, ANN THCUAC SURG 1986, 42 Vancouver, BC, Canada V6T 1W5 - (3) 307 EUR J PHAFMACOL 1986, -128 (l-2) 25

Kitamura Y, Nomura Y*//*Toyama Med & Pharmaceut Univ, Dept Pharmacol, Lrakan Yaku Oriental Med Res Inst, 2630 Sugitani, Toyama 93001, Japan JPN J IHARMAO)L 1986% (2) 321 Enhancement of [3H]clonidine birding to rat cerebral synaptic membranes by treatment with arachidonic irid, prostsglandin (PG) D2, P(E2, and PGF2alpha Persaud 'NN//Univ Manitoba, Dept Anat, Winnipeg, Manitoba, Canaia R3E a53 PROSTAGLAND IEUK MED 1986, 24 (1) 75 Fetal mtcane followirg axeternal treatment with irostqlandin E2 Jaschonek K, Rem W, Weisenberger H//Univ Tubirgen, Mad Klin, Otfried Muller Str 10, D-7400 Tubingen 1, W Germany PROSTAGlAND IEUK MED 1986, E (1) 79 The birding of 6-oxo-prostaglardin El to platelet prostanoid receptors Vincent JL, Domb M, Goldstein J, Lignian H, van Belle J//Erasm Univ Hasp, Dept Intens Care, Route Lennik 808, B-1070 Brussels, Belgium PROSTAGLAND LEUK MED 1986, 24 (1) 87 Absence of myocardial protectionwith prostacyclin during cardiac arrest Sethi GK, Bridgman AH, King L, Scott SM/lVet Adm Med Ctr, Div Cardiovasc 6 Thorac Surg, Asheville, NC 28805, USA AMER SJRG 1986, x (9) 474 IntravenaJs infusion d Foatglardi" El (Pal) in management of limb ischemia Risberg B, BergdaN S, Kjellstran BT, Ortenwall P, Seanan T//Gothenburg Univ, E Hasp, Dept Surg, S-41124 Gothanburg, Sweden ACIA CHIR SCAND1986, -152 (JUT-Jul) 477 Beneficial effect of treatment with a prostacyclin analcgue in severe peripheral atherosclerosis Kroner M, Grarmuller Gl/Besirkskrankenhauses Gara, Fraue&lin, Vollersdorfer Str 45, DIR-6500 Gera, E GeIXla"y ZBL GYNAKOL 1986, 108 (16) 995 Priming ani tberapzic sbortion by prosttilglanjin-F2-alpha Young IM, Anderson DB//Upjohn Ltd, Fleming Way, Crawley, W Sussex, England THBFJOGENOLOGY 1986, 26 (2) 199 Imprwed reproductive performance fras dairy cows treated withdinoprost tranethamine soon after calvirg

Whittier JC, Deutscher GH, Clanto" DC//lJniv Missouri, Dept Anim Sci, Columbia, MO 65211, USA J ANIM SC1 1986, 63 (3) 700 Progestin an3 prostaglandin for estrous svnchronization in beef heifers Zimmerman JJ//Univ Wisconsin Hosp, Ctr Clin Sci, Dept Pediat, 600 Highland Ave, Madison, Wi 53792, USA GRIT CARE MED 1986, 14 (9) 761 Pharmacologic modulation by prostaglandin El of superoxide anion production by human polymorphonuclear leukocytes 15. INHIBITORS OF SYNTHESIS Bomalaski JS, Hirata F, Clark MA//Vet Adm Med Ctr, Ctr Arthritis Immunol, 39th b Woodland Ave, Philadelphia, Pa 19104, USA BIOCHEM BIOPHYS RES COMMUN 1986, -139 (1) 115 Aspirin inhibits phospholipase C Catravas JO, Hofman WF, Ehrhart IC//Med Co11 Georgia, Dept Pharmacol 6 Toxicol, Augusta, Ga 30912, USA J APPL PHYSIOL 1986, $l_ (3) 1035 Prostanoid inhibition potentiates vasoconstrictor response to acetylcholine in dog lung Sprague RS, Stephenson AH, Dahms TE, Lonigro AJl/Vet Pdm Med Ctr, Med Serv, St Louis, MO 63125, USA J APPL PHYSIOL 1986, 61 (3) 1058 Effect of cyclooxygenase inhibition on Pthchlorvynol-induced acute luna injury in dogs Lauritsen K, Laursen LS, Bukhave K, Rask-Madsen J*//*Univ Copenhagen, Bispebjerg Hasp, Dept Med B, Gastroenterol Sect, DK-2400 Copenhagen NV, Denmark GASTROENTEROLCGY 1986, 91 (4) 837 Effects of topical 5-aa&osalicylic acid and prednisolone on prostaglanjin E2 and leukotriene B4 levels determined by equilibrium in viva dialysis of rectum in relapsing ulcerative colitis Alexandre A, Doni MG, Padoin E, Deana R//Univ Padua, Inst Biol Chem, CNR, Study Mitochotirial Physiol, I-35131 Padua, Italy BIOCHEM BIOPHYS RES COMMUN 1986, -139 (2) 509 Inhibition by antioxidants of agonistevoked cytosolic Ca2+ increase, ATP secretion, and aggregation of aspirinated human platelets Demo1 P, Schmitz HD, Weihrauch TR, Kuhlmann J//Bayer AG, Dept Clin Pharmacol, Appra Ther Weg, D-5600 Wuppertal 1, W Germany ARZNEIM-FORSCH-DRUG RES 1986 36-2 (9) 1406 Prevention of the acetylsalicyclic acid-induced charges of the gastric potential difference by the new synthetic prostaglardin-El analmue rioprostil Metz SA//Univ Colorado, Hlth Sci Ctr, Dept Med. Div Clin Pharmacol, C-237, 4200 E 9th Ave, Demrer, Co 80262, USA J PHARMACOL EXP THER 1986 238 (3) 809

Para-hydroxymercuribenzoic acid inhibits arachidonic acid esterificalion into 2 distinct ~01s ard stimulates insulin release in intact rat islets

tfiect 01 dter"ate-day i%~:!~~ rili Pnteric-coated aspirin on platelet aggregation, bletdi"g time, ard thromboxane A2 levels in bleejis-tlwure blood

Scharschmidt L, Simonson M, Dunn MJ//Yeshiva Univ Albert Einstein Co11 Med, Dept Med, Div Rend, Bronx, NY 10461, USA AMER J MED 1986, fi (28) 30 Glomerular prostaglandi"s, angiiotensin II, and nonsteroidal anti-inflammatory drugs

17. ANALOGUES AND CHEMICAL SYNTHtSIS Lieb F. Werdisch DllBaver AC. Zcnr Bereich Zent Forsch; 0:SOY0 Lev ' c r4use", W Germany LIEBIGS ANN CHUa lY86, (9) I','8 Synthesis of prostanoids fran rret!lyl 3-formyl-2,2-dimet~lcyclopr-opanrc~rboxylnte (German)

Brow" J, Dollery C, Valdes G//Royai Postgrad Med Sch, Dept Nephrol, Ducane Rd, Lotion W12 OHS, England AMER J NED 1986, 81 (2B) 43 Interaction of nonsteroidal antiinflammatory drugs with antihypertensive and diuretic qents: control of vascular reactivity by endogenous prostanoids

Wang Y, Li J, Wu Y*, Hua;g Y, bhi i_, Yaw .Ji/*Chinese Acad Sci, Shai):hdi Inst Organ Chem, Dept Ist, 345 Lini,ling lu, Shanghai, Peoples R Chj"a TETRAHEDRON IETT 198b, 27 (38) 4583 A facile stereoselective synf.hrsisot leukotriene A4 (LT.44)methyl e~~I.r

Seder JR, Davidson EW, Dunn MJ//U"iv Hasp Cleveland, Div Nephrol, Abington Rd, Clevelad, Oh 44106, USA AMER J MED 1986, 81 (28) 58 Effects of nonsteroidal anti-itilammatory drugs in healthy subjects Patron0 c, Pierucci A*//*Univ Sapienza, Policlin lhnberto 1, Med 2, I-00100 Rome, Italy AMER J MED 1986, 81 (28) 71 Renal effects of norsteroidal inflammatory drugs in chronic ular disease

Roma La 1st Clin

antiglomer-

Vriesendorp R, Danker ABJM, DeZeaw D, De Jong PE, Van Der Hem GK, Brentjens JRH//Westeinde Ziekenhuis, Lynbaan 32, POB 432, 2501 CK Denhaag, Nether-lards AMER J MED 1986, 81 (ZB) 84 Effects of nonstezidal anti-inflammatory drugs on proteinuria Zipser F?D//Univ Calif Los Angeles, Los Angeles Cty Harbor Med Ctr, Dept Med, Div Gastroenterol, Cl Trailer, Torrance, Ca 90509, USA AMER J MED 1986, g (2B) 95 Role of renal prostaglandins ad the effects of nonsteroidal anti-inflammatory drugs in patients with liver disease Arroyo V, Gines P, Rimola A, Gaya J//Hasp Clin & Provincial, Unidad Hepatol, Villarroel 170, E-08036 Barcelona, Spain AMER J MFaD 1986, 81 (2B) 104 Renal function abznnalities, prosraglandins, and effects of "onsteroidal anti-inflammatory drugs in cirrhosis with ascites: an overview with Bnphasis on pattwgenesis Cannon PJ//Columbia wliv Co11 Phys & Surg, Dept Med, New York, NY 10032, USA AKR J MED 1986, 81 (28) 123 Prostaelandins incowestive hart failure ard the effects of nonsteroidal anti-inflammatory drugs Stampfer MJ, Jakubowski JA, Deyki" D, Schafer AI, Uillett WC, Hennekens CH//55 Pord Ave, Brookline, Ma OLi46, USA AMEK .J MELl 1986, 81 (3) 400

Okamoto S, Shimazaki 'I', <(iL,d"<, :, Kobayashi Y, Sate Fy//*Tokyo lit>,: Technol, D.?pt Chen Eng", Megux-ii h :I, Tokyo 152, Japan J CHtM SCC OiFM U)MMUN lY80, (Ii) ,351 A practical preparation or 4 pha~hydroxy anj alpha,betrrdihydroxy aldehydes, useful intennrdldtes for the synthesis of arachldonic acid metabolites, starti% with I>-glycai-,+ldehyde acetonide Bergawn NA, Chiarg Y, Ja"smlilM, Kresge AJ, Ya ~JlCha~~mers Ilniv Trcirnoi, Dept Organ Chem, S-41296 Gothenburg, Swede" ,JCHEM SIX U-IEM CUMMUN lYH6, (i/) :ih6 (Z)-6,9~poxynon-5-eno~~~ xid: 1 simple model which mimics the wusuai hvdrolvtic lahilihi of irwtarvrli n Nagaoka H, Miyaoka H, Miydkoini T, Yamada Y"//*Tokyo Co11 Phan, Hachioj;, Tokyo 19203, &pan J AMER UiEM See: 1986, IOk (lo) >!,LY Synthesis ot pu~aglard~" iiard I. Revision of the structures Suzuki 21, Morita Y, Yan*:isdw,, A, Noyori R*, BakerBJ, Sctleuei PJ,, *Nagoya Univ, Dept Chen, Chikuqn kll, Nagoya, Aichi 464., Japa~~ .IAMER QltM SU_ 1986, 108 Clb) ‘ Iv:, Synthesis of (7E)- ard ~O-p~n_ut,i"di-~ 4. Structural TtVLd10,, Kobayashi Y, K~ta"" Y, Mntsilinor,, L, Sate F*//*Tokyo Inst Technot, l)e,i~ Chem Engn, &guru ku, Tokyo 151, .I:,~~~, TETRAH~RON IETT 1986, L?_ (39) *7/s A praclical rrrtbii fur mullxgra iiidii synthesis "t (+)-metal 5(5),6(R)e~xy-6-formythexalloale ani .?(K),?(X)epoxyoctanal , kry intermediatei to; svnthesis of leu!atric"cs A4 Codi~roid .I.J, ttevmns I,‘, brcqlr : 'C//U"iv Parip !I,, Pharmacoch ir,MoLeiL.ih, 2 Pi .J,is\ie,,F-75251 Par i:,05, France PtiAIIMAWL KiS (UMMUJIV 1gHb 18 (,,u>r)s,, Svnthesrs 01 ether plmsplwli pi.!-

Ii.i w,il,, xj Siafaka-Kapada i ,A/!5ocial I"!, Fd" Ikr, LJept Chum , H e: ho 115 L.i,it I ii,,. St, 6K-10241 4tt,ens,(;'t'..C,. 1 LHK(PIATiXK 14Hb, 3_C! i', ,I,'

High-performance liquid chranatographic analysis of platelet activatix factor on a cation-exchaqe column by direct ultraviolet detection Jemal M, Ivashkiv E, Valatin P, Cohen AI//Squibb Inst Med Res, POB 191, New Brunswick, NJ 08903, USA J CHROMATCGR 1986, 381 (2) 424 Determination of thomboxane A2 receptor antagonist in human plasma by capillary gas chromatography with electron-capture detection Kelly RW, Dean S, Cameron MJ, Seamark RF//lJniv Edinburgh. Ctr Reprod Biol, MRC, Reprod Biol Unit, 37 Chalmers St, Edinburgh EH3 9EW, Scotland PROSTAGLAND LeUK HED 1986, 24 (1) 1 Measurement by radioimmunoassay of prostaglandins as their methyl oximes Uderman HD, Workman IW//Univ Massachusetts, Sch Med, Dept Pharmacol, Worcester, Ma 01605, USA PROSTAGIAND LEUK MBD 1986, 24 (1) 69 A simplified method for the%dination of prostanoids for radioimmunoassay Shea R-F, Tai H-H*//*Div Ned Chem & Pharmacognosy, Co11 Pharm, Univ Kentucky, Lexington, Ky 40536-0082, IJSA J BIOL CHM 1986. 261 (25) 11585 Monoclonal antibod= to thromboxane synthase from porcine lung. Production and application to development of a tatieem immunoradiometric assay

20. FORTHCOMING EVENTS Gordon Research Conferences: 1987 Winter Schedule The Winter Gordon Research Conferences will be held 5 January to 27 February 1987 at the Miramar Hotel, Santa Barbara, California Requests for applications to the Conferences or for dditional information should be ddressed to: Dr Alexander M Cruickshank, Director, Gordon Research Conferences, Gordon Research Center, University of Rhode Isalnd, Kingston, RI 02881, USA

TWICE MONTHLY BIBLIOGRAPHY ON PROSTAGLANDINS - LATE NOVEMBER PREPARED BY SHEFFIELD UNIVERSITY, BIOMEDICAL TNFORMATION SERVICE SHEFFIELD SlO ZTN 2 GENERAL Gerhart DJ//Univ Hawaii Manoa, Dept Chem, 2545 Mall, Honolulu, Hi 96822, USA BIOCHEM SYST ECOL 1986, 14 (4) 417 Prostaglandin A2 in the Caribbean Gorgonian Plexaura homomalia: evidence against allelopathic and antifouling roles 3 PROSTAGLANDINS E AND F Jackson BA//U"iv Kentucky, Co11 Med, Dept Physiol & Biophys, Lexington, Ky 40536, USA J CELL PHYSIOL 1986, -129 (1) 6O Prostaglandi" E2 synthesis in the inner medullary Collecting duct of the rat: implications for vasopressindependent cyclic AMP formation Watanabe N, Abiko Y//Nihon Univ, Sch Dent, Dept Orthodont, Matsudo, Chlba 271, Japan GEN PHARMACOL 1986, c (5) 525 Effect of sixth component of complement on the prostaglandin El stimulated adenyl cyclase activity in rat calvarla Liu C-M, Okayasu T, Goldman P, Suzuki Y, Suzuki K, Wheelock EF*//*Hahnemann Univ, Dept Pathol 6, Lab Med, Philadelphia, Pa 19102, USA J EXP MED 1986,X (4) 1259 Immune regulation of the L5178Y murine tumor-dormant state. 1 In vlvo and in vitro effects of prostaglandin E2 and indomethacln on tumor cell growth Balavoine JF, Derochemonteix B, Williamson K, Seckinger P, Cruchaud A, Dayer JM*//*U"iv Geneva, Hop Cantonal, Dept Med, Div Immunol 6 Allergy, Hans Wilsdorf Lab, CH-1211 Geneva 4, Switzerland .I CLIN INVEST 1986, 78 (4) 1120 ProstaglandivE2 and collagenase production by fibroblasts and synovial cells is regulated by urine-derived human interleukin-1 and inhibitor(S) Siler-Khodr TM, Khodr GS, Valenzuela G, Harper MJK, Rhode .J//Unlv Texas, Hlth Sci Ctr, D?pt Obstet 6 Gynecol, 7703 Floyd Curl Dr, San Antonio, TX 78284, USA BIOL REPROD 1986, 35 (2) 312 GnRH effects on placental hormones during gestation. III. Prostaglandin E, prostaglandIn F, and 13,14-dlhydro15-keto-prostaglandin F Walsh LJ, Seymour GJ, Powell RN//Univ Queensland, Dept Social & Prevent Dent, Brisbsne, Qld 4000, Australia J ORAL PATH 1986,g (6) 347 ModulatL0" 0f class II (DR and DQ) antigen expression on glngival Langerhans cells in vitro by gamma interferon and prostaglandin E2 Mocha" E, Uhl J, Newton R//Unlv Med h Dent New Jersey, Sch Osteopath Med, Dept Family Med, 401 Haddon Ave, Camden, NJ 08013, USA ARTHRITIS RHEUM 1986, 29 (9) 1078

Avidence that interleukin-1 induction of synovial cell plasminoge" activator is mediated via prostaglaidnin-E2 and CAMP Jordan ML, Hoffman RA, Simmons RL// Univ Minnesota, Dept Surg, Box 185, Mayo Mem Rlvd, Minneapolis, Mn 55455, I;SA TRANSPLANT PROC 1986 18 (5) 54, 104 Allosensitized helperbut not lytic T lymphocyte clones are functionally inhibited by prostaglandin E2 Perez RV, Munda R, Heyd TJ, Alexander JW//Unlv Cincinnati, Med Ctr, 231 Rethesda Ave, Cincinnati, Oh 45261, USA TRANSPLANT PROC 1986 18 (5) S4, IlO The effect of donor-specific transfusions, 16,16-dimethyl PGE2 and dietary prostaglandin precursors on rat cardiac allograft survival Saito H, Noguchi K, Winters SJ, Kee0l"a - HS, Oshima H. Troen p*// *Montefiore Hasp, Dept Med, 3459 5th Ave, Pittsburgh, Pa 15213, USA ENDOCRINOLOGY 1986 -119 (4) 1733 Testicular control of prostaglandin E2 production in rat vas deferens

Shimanuki T, Nakamura RM, diZerega CS//rJnlv So Callf, Sch Med, Dept Obstet h Gynecol, Livingston Reprod Rio1 Lab, Los Angeles, Ca 90033, USA .J SURG RES 1986, 41 (3) 245 A kinetic analysis of peritoneal fluid cytology and arachidonic acid metabolism after abrasion and reabrasion of rabbit peritoneum Wey HE, Jakubowski JA*, Devkin D//*Ver Adm Med Ctr Jamaica Plain, Dept Hemostasis Res, 150 S Huntington Ave. Roston, Ma 02130, USA BIOCHIM BIOPHYS ACTA 1986, 878 (3) 380 Incorporation and redistribxon of arachidonic acid in dlacyl and ether phospholipids of bovine aortic endothelial cells Blftu T, Gamble NF, Doebbrr T, Hwang SB, Shen TY, Snyder 3, Springer JP, Stevenson R//Merck Sharp & Dohme Res Labs, Rahway, NJ 07065, USA .IMED CHEM 1986, 2 (IO) 1917 Conformation and activity of tetrahvdrofuran lignans and analagues as specific platelet activating factor a"tago"1sts

Roukili MA, Bureau M, Lagente I:, Lefort J, Lellouch-Tubiana A, Malanchere E, Vargaftig BB//I"st Pasteur, INSERM, Galchinskaya VY, Rombugoslavskaya ES, Lille YE//Kharkov Endocrinol & Hormone U285, Dept Physiopathol Exptl, 28 Rue Dr Roux, F-75724 Paris 15, France Chem Res Inst, Endocrine Dis Biochem BRIT .I PHARMACOL 1986, j_!!(2) 349 Lab, Kharkov, LJKSSR, USSR Pharmacologlcal modulation of the BULL EXP BIOL MED ENGL TR 1986, -101 effects of N-formyl-L-methionyl(3) 308 L-leucyl-L-phenylalanine in guineaInteraction of prostaglandinsE2 with receptors and their effect on adenylate pigs: Involvement of the arachidonic acid cascade cyclase activity in human thyroid gland tissue Wallace .JL,Whittle B.JR//WellcomeRes Labs, Dept Mediator Pharmacol, Beckenham Sawka CW, Desforges JF*//*New England RR3 3BS, Kent, England Med Ctr, Dept Med, Div Hematol Oncol, RRIT J PHARMACOL 1986, 89 (21 415 171 Harrison Ave, Boston, Ma 02111, Effects of inhibitors ofarachidonlc USA acid metabolism on Paf-induced qastrlc EXP HEMATOL 1986,s (9) 873 necrosis and haemoconcentraTarget cell for prostaglandln-E In the mucosal stimulation of in vitro human erythrold tion correlation (BFu-E) progenitor cells Goldyne ME//Vet Adm Med Ctr, Dept of Ia antigen expression with the Dermatol, MS 190. San Francisco. Ca stimulatorv effect 94121, USA TRANSPLANT PROC 1986 18 15) S4, 37 5 PRECURSORS - Arachidonic Acid Moscat J, Moreno F, Herrero C, Iglesias Lymphocyte and monocytefmacrophage S, Garcia-Barren0 P//Hasp Prov Madrid, interactions involving arachidonic acid metabolism Dept Exptl Med, Dr Esquerdo 46, E-28007 Madrid, Spal" Abou-Samra A-B, Catt KJ, Aguiiera BIOCHEM BIOPHYS RES COMMUN 1986 G//NICHHD, Endocrinol & Reprod Res 139 (3) 1098 Branch, Bldg 10, Room 8C407, Bethesda, Gchidonic acid releasing systems in Md 20892, USA pig aorta endothelial cells ENDOCRINOLOGY 1986 119 (4) 1427 Role of arachidonicacld in the Chien EJ, Kostellow AB, Merrill regulation of adrenocortlcotropin GA//Yeshiva Univ Albert Einstein Co11 Med, Dept Physiol & Biophys, Bronx, NY release from anterior pituitary cell cultures 10461 USA LIFE SC1 1986, 39 (17) 1501 Progesterone lnductlon of phospholipld Eling TE, Danllowicz RM, Henke DC, Sivarajah K, Yankaskas JR, Boucher methylation and arachidonic acid RC//Natl Inst Environm Hlth Sci, Lab turnover during the first meiotlc Molec Biophys, Res Triangle Pk, NC dlvislon in amphibian oocytes 27709, USA

J BIOL CHEM 1986, 261 (27) 12841 Arachldonic acid metabolism by canine tracheal epithelial cells. Product formation and relationship to chloride secretion 6 Leukotrienes Sugano M, Ishida T, Ide T//Kyushu Univ, Sch Agr, Nut; Chem Lab; 46-09, Fukuoka 812, Japan AGR BIOL CHEM TOKYO 1986 50 (9) 2335 Effects of various polyunsaturated fatty acids on blood cholesterol and eicosanoids in rats Snyder G, Lattanzio F, Yadagirl P, Falck JR, Cepdevila J//U"iv Texas, Hlth Sci Ctr, Dept Physiol, Dallas, TX 75235, USA BIOCHEM BIOPHYS RES COMMUN 1986 139 (3) 1188 ?&qoxyeicosatrie"oic acid mobilizes Ca2+ in anterior pituitary cells Naughton JM, Trewhella MA*//*Footscray Inst Technol, Dept Chem & Biol, Footscray, Vie 3011, Australia COMP BIOCHEM PHYSIOL PT B 1986 E (1) 139 Presence of delta5,11,14-eicosatrienoic acid in liver phosphoglycerides of the echidna (Tachyglossus aculeatus) Moller A. Schwanitz HJ. Czarnetski BM*//*Hoffman" La Roche h Co Ltd, CH-4002 Basel, Switzerland J INVEST DERMATOL 1986, 87 (4) 489 In vitro generation of chemotactic leukotrienes from unfractionated murine epidermal cells Kragballe K, Pinnamanenl G, Desjarlais L, Duel1 EA, Voorhees JJ//Narselisborg Hosp, Dept Dermatol, DK-8000 Aarhus C, Denmark J INVEST DERMATOL 1986, 87 (4) 492 Dermis-derived 15-hydroxy-eicosatetraenoic acid inhibits epidermal 12lipoxygenase actlvlty Wawrose SF, Brezinski ME, Lefer AM//Thomas Jefferson Univ, Jefferson Med Coll, Dept Physiol, Philadephia, Pa 19107, USA IRCS MED SCI-BIOCHEM 1986 e (9) 908 'Inhibition of pulmonary generatlo" of leukotrlenes by a variety of calcium channel blockers Payan DG, Wong MYS, Chernov-Rogan T, Valone FH, Pickett WC, Blake VA, Gold WM, Goetsl EJ//Univ Calif San Francisco Med Ctr, Howard Hughes Med Inst, San Francisco, Cs 94143, USA J CLIN IMMUNOL 1986, 2 (5) 402 Alterations in human leukocyte function induced by ingestion of eicosapenteenoic acid ~amwell PW//Georgetown Univ, Ned Ctr, Dapt Physiol 6 Biophys, Washington, DC 20007, USA TRANSPLANT PROC 1986 18 (5) S4, 5 Eicosanoids

Ford-Hutchinson AW//Merck Frosst Canada Inc, POB 1005, Pointe Claire, Quebec, Canada H9R 4P8 TRANSPLANT PROC 1986 g (5) S4, 33 Alternative fatty acids and the production and action of leukotriene B Rola-Plesacsynski M, Gagno" L//U"iv Sherbrooke, Fat Med, Dept Pediat, Div Immunol, 3001 12E Ave Nerd, Sherbrooke, Quebec, Canada JlH 5N4 TRANSPLANT PROC 1986 18 (5) S4, 44 Natural killer cell f&tion modulated by leukotriene B4: mechanisms of action Goodwin JS//Med Co11 Wisco"si", Dept Med, Milwaukee, Wi 53226, USA TRANSPLANT PROC 1986 3 (5) S4, 49 Role of leukotriene 84 in T cell activation Busija DW, Leffler CW, Beasley DG// Univ Tennessee, Ctr Hlth Sci, Dspt Physiol 6 Biophys, 894 Union Ave, Memphis, 'i-n 38163, USA PEDIAT RES 1986, 20 (10) 973 Effects of leukotrienes C4, D4, and E4 on cerebral arteries of newborn pigs Goldberg RN, Suguihara C, Streitfeld MM, Bancalari A, Clark MR, Bancalari Pediat E//Univ Miami, Sch Ned, I!.?pt R131, Div Neonatal, POB 016960, Miami, Fl 33101, USA PEDIAT RES 1986, 20 (10) 1004 Effects of a leukotriene antagonist on the early hemodynamic manifestations of group-B streptococcal sepsis in piglets 7 Prostacyclin El Tahir KEH, Ali AE, Nasif MAA, Ageel AM, Gadkarim EA//King Saud Univ, Co11 Pharm, Dept Pharmacol, POB 2457, Riyadh 11451, Saudi Arabia ARCH INT PHARMACODYN THER 1986, -283 (1) 134 The influence of oral hypoglycaemic sulfonyl ureas on prostacyclin release by the rat thoracic aorta Taylor Gw, Chappell CG, Fraser CE, Ritter JM//Hammersmith Hosp, Royal Postgrad Med Sch, Dept Clin Pharmacol, Ducane Rd. London W12 OHS, England BIOCHEM J 1986, 239 (1) 237-239 Prostacyclin synzsis by vascular tissue. Effect of extracellular CaZ+ Zahavi M, Zahavi J//Tel Aviv Med Ctr, Dept Med, Day Clin, Tel Aviv, Israel THROMB RES 1986. 46 (1) 119 Relative insensitivity of epinephrine induced platelet aggregation to prostacycli" Clark MA, Conway TM, Bennett CF, Crooke ST, Stadel JM//Dept Molec Pharmacol, Smith Kline & French Labs, PO Box 7929, Philadelphia, Pa 19101, USA PROC NATL ACAD SC1 USA 1986, 3 (19) 7320 Islet-activating protein inhibits leukotriene D4- and leukotriene C4but not bradykinin- or calcium ionophore-induced prostacyclin synthesis in bovine endothelial cells

8 Thromboxanes Mehta P, Lawson D, Ward MB, LeeAmbrose L, Kimura A//Univ Florida, Co11 Med, Dept Pediat, Box J-296, JHMHC, Gainesville, Fl 32610, USA CANCER RES 1986, '16 (10) 5061 Effects of thromboxane A2 inhibition on osteogenic sarcoma cell-induced platelet aggregation 9 METABOLITES Dicsfalusv U. Hambern M//Huddl"ge Univ Hosp, Karblinska Ins;, Dept Clin Chem 1, S-14186 Huddinge, Sweden BIOCHIM BIOPHYS ACTA 1986, Q (3) 387 Identification of the major urinary metabolite of prostaglandin E3 in the rat 10 RELATED ENZYMBS Efendiev AM. Pomoinetskii VD. Kubatiev AA//Moscow Cent Postgrad Med Training Inst, Moscow, USSR BULL EXP BIOL MED ENGL TR 1986, -101 (3) 303 Prostaglandin synthetase activity in layers of the kidney of young rats receiving polyene antibiotics Burch RN, Luini A, Axelrod J//Lab Cell Biol, Nat1 Inst Mental Hlth, Bldg 36/Roam 3A15, Bethesda, Md 20892, USA PROC NATL ACAD SC1 USA 1986, 83 (19) 7201 Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alphaladrenergic stimulation in FRTLS thyroid cells 11 PRODUCTION AND RELEASE Dieter P, Schulze-Specking A, Decker K*//*U"iv Freiburg, Inst Biochem, Univ Hermann Herder Str 7, D-7800 Freiburg, W Germany EUR J BI0CHF.M 1986 159 (3) 451-457 Differential inhibition of prostaglandin and superoxide production by dexamethasone in primary cultures of rat Kupffer cells Muramatsu M, Tanaka M, Murakami S, Aihsre H//Taisho Pharmaceut Co Ltd, Res Ctr, Omiya, Saitama 330, Japan RES COMMUN CHEM PATHOL PHAP.M 1986, 12 (3) 289 Effect of sofalcone on gastric mucosal prostaglandi" metabolism in taurocholate induced gastritis in rats Lynch JN, Henson PM//Univ Colorado, Hlth Sci Ctr, Dspt Med, Dlv Rheumatol, Box B115, 4200 E 9th Ave, Denver, Co 80262, USA J IMMUNOL 1986 137 (81 2653 The intracellularretention of newly synthesized platelet-activating factors Bunke M, Itskovits H//Univ Louisville, Div Nephrol, 500 S Floyd, Louisville, Ky 40292, USA J LAB CLIN MED 1986, 108 (4) 332 Urinary excretion and-&al production of prostaglandins E2, FLalpha, and thromboxane 82 in experimental diabetes mellitus

Suggs .JE, Madden MC, Friedman N, Edge11 CJS*//*U"iv N Carolina, Dept Pathol 228H, Chapel Hill, NC 27514, USA BLOOD 1986, 68 (4) 825 Prostacyclin expression by a continuous human cell line derived from vascular endothelium

Chung HT, Burnham DK, Kobertson I:, Roberts LK, Davnes RA*//*U"iv Utah, Med Ctr, Sch Med, Dept Pathol, Salt Lake City, Ut 84132, IJSA .I IMMlINOL 1986,X (8) 247R Involvement of prostaglandins in the immune alterations caused by the exposure of mice to ultraviolet radiation

Glare AS, van Elk R, Feyen .JHM//U"iv Newcastle Upon Tyne, Dept Zool, Newcastle Tyne NE1 7RU, Tyne & Wear, England INT J INVER REPROD DEVEL 1986, fi (2) 125 Elcosanoids; their biosynthesis in accessory sex organs of Lymnaea stagnalis (L.)

Farrar WL, Beckner SK//NCI, Frederick Cant Res Facil, Dlv Cant Treatment, Biol Response ?lodifiers Program, Frederick, Md 21701, USA TRANSPLANT PROC 1986 _@ (5) $4, 25 Biochemical convergence of prostaqlandins and interleukin ? on the adenylate cyclase system

Nakamura T//Kyuchu Univ, Fat &I-, Fisheries Chem Lab, 6-10-l Hakozaki, Fukuoka 812, Japan LIPIDS 1986, 21 (9) 553 Prostaglandinxike substances formed during autoxidation of methyl linolenate

Jones RL, Watson ML*//*Royal Infirm Edinburgh, Med Renal Unit, Edinburgh EH3 9YW, Midlothian, Scotland CLIN SC1 1986, 71 (5) 527-532 vascular sensitivity to prostaglandin 12 and urinary excretion of 6keto-prostaglandin Fl in conscious dogs

12 EFFECTS Zijlstra FJ. Vincent .JE//Erasmus Univ, Fat Med, De& Pharmacol, POB 1738, 3000 DR Rotterdam, Netherlands GEN PHARMACOL 1986,c (5) 585 Sotalol potentlates the leukotrienr C4-induced contractlons and thromboxane A2 release of guinea pig lung parenchymal strips

Watson ML, .Jones RL//Royal Infirm Edinburgh, Med Renal Unit, Edinburgh EH3 9YW, Midlothian, Scotland CLIN SC1 1986, 71 (5) 533-53R The contribution of PG12 to the effects of captopril in conscious dogs in differing states of sodium halance Mere" H, Varin F, Ruwart M, Thurman RG*//*Univ N Carolina, Sch Med, Dept Pharmacol, Chapel Hill, NC 27514, USA HEPATOLOGY 1986, 6 (5) 917 Effect of lh,lb-dimethyl prostaglandin ~2 on oxygen uptake and microcirculation in the perfused rat liver

Foidart JB, Mahieu P//State Univ Liege, Inst Med, Dept Med, 66 BD Constitut, B-4020 Liege, Belgium MOL CELL ENDOCRINOL 1986, 41 (l-2) 163-173 Glomerular mesangial cell contractility in vitro is controlled by an angiotensinWarnick JE, Pellmar TC*//*Armed Forces prostaglandin balance Radiobiol Res Inst, Dept Physiol, Bethesda, Md 20814, USA Al-Ugaily L, Thulesius 0, AngeloNEUROSCI LETT 1986, 70 (2) 2Y5 Khattal'M//Kuwait Univ, Fat Med, Dept Resistance of afterhyperpolarizations Anat b Pharmacol Toxicol, Kuwait City, in hippocampal pyramidal cells to Kuwait prostaglandins and vasoactlve SCAND J UROL NEPHROL 1986, 20 (3) 225 intestinal polypeptide (VIP) New evidence for prostaglandl" induced motility of the ureter Kunigelis SC, Saleuddi" ASM*//*D"ke Univ, Dept Zool, Durham, NC 27706,USA Bjoro K, Stray-Pedersen S//U"iv Oslo, INT J INVER REPROD DEVEL 1986, g (2) Nat1 Hosp, Dept Obstet h Gynaecol, 159 N-00270 Oslo 1, Norway Reproduction in the freshwater ACTA OBSTET GYNECOL SCAND 1986, 65 (5) gastropod, Helisoma: Involvement of 467 prostaglandin in egg production In vitro perfusion studies on human umbilical arteries. II. Effects of 13 PROSTAGLANDINS IN MEDICINE prostacyclin and a thromboxane A2 Friedman Z//Baylor Co11 Med, Dept mimetlc Pediat, Houston, TX 77030, USA ENDOCRINOL EXP 1986, 0 (2-3) 285 Schuetz AW//Johns Hopkins Univ, Sch Prostaglandins In breast milk Hyg 6 Pub1 Hlth, Dept Populat Dynam, 615 N Wolfe St, Baltimore, Md 21205, Rauramaa R//Kuopio Res Inst Exercise USA Med , Puistokat" 20, SF-70100 Kuopio, GAMETE RES 1986, 15 (2) 99 Finland Hormonal dissociation of ovulation and ACTA MED SCAND 1986, Sp 711 137 maturation of oocytes: "v"lati"" of Physlcal activity and prostanoids Immature amphibian oocytes by prostaglandin McIntyre RW, Flezzani P, Knopes KD, Reves JG, Watkins WD//Duke lJniv,Med Murakami S, Marl Y*//*Toky" Co11 Wrham, NC Ct-t-,Dept Anesthesiol, Pharm, Dept Blochem, 1432-I Horinouchi, 27710, USA Hachioji, Tokyo 19203, Japan AMER J CARDIOL 1986, 58 (9) 857 J PHARMACOBIPDYNAM 1986, 2 (9) 760 pulmonary hypertension and prostaChanges in the structure of rat mucous glandlns after protamlne glycoprotein and prostaglandin cytoprotection

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T..r, Coccaro EF, Davis KL//Vet Adm Yed Ctr, Psychiat Serv 116A, 130 W Kingsbridge Rd, Bronx, NY 10468, I'S:% ARCH GEN PSYCHIAT 19R6, 43 (10) 957 Prostaglandi" receptor seOsitivii\, ids nyvchiatric disorders Y't01 er a://Pla Ce" iiosp,Beij ini', Peoples K China CHIN MED J 1986, 98 !I:)) :;i Experimental and clinical study of prostaglandin E in gastrointestinal disease Chignard M, l,eCouedii .:I~, Andersso" P, Brange C//Temple Univ, Hlth SC1 ctr, Sch Med, Thrombosis Res Ctr. 1400 N Broad St, Philadelphia, Pa 19140, USA INT ARCH ALLERCY APPL IMMUNOL 1986, 81 (2) 184 use of steroidal antiinflammatory drug provides further evidence for a potential role of ?AP-acether in hroncbial anaphylaxis Rokacb -1, Fitzsimons B//Merck Frosst Canada Inc, POB lnoi, Pointe Claire, Ouebec, Canada H9R 4P8 TRANSPLANT PROC 1986 18 (5) S4, ? Lipoxins - do they ha% a biological role? Foegh ML, Alljani MK, Helirich i,H, Khirabadi BS, Lim K, Ramwell PW//Georgetow" Univ, Med Ctc, DepC Surg, Dlv Transplantat, Washington, DC 20007, USA 'TRANSPLANT PROC I946 18 (5) 54, 20 Lipid mediators in orz" tfansplantation Hayry P, Ferry B, Leszczynski i1, Yanca F, .Iaakkola M, Halttune" I, vo" Willebrand E, Schellekena H, Meide Pv//Univ Helsinki, Trans.plantat Lab, Haartmaninkatu 3, SF-00290 Helsinki 29, Finland TRANSPLANT PROC 1986 1" (5) S4. 5: Generation and breakdown of a vicious cycle in context of acutr allograft rejection Mangino M.1, Anderson CH, DeSchrvver K, Tyler JD, Sicard CA, Tut-k JP//Washington Unlv, Sch Med, Dept surg , St Louis, MO 63110, USA TQANSPLANT PROC 1986 18 (5) $4, h! Ficosanoid synthesis associated witr renal allograft rejection Kelley VE//Rrigham b Womens Has!,. lmmunogenet & Transplantat Lab, 75 Francis St, Boston, Ma 02115, USA TRANSPLANT PROC 198h 18 (5) S4, 77 A role for thromboxane in immune mediated renal injury Pauber:-Braquet MjlHop I"str\ict Armees Percy, Ctr Burn, Clln Res ITnit, F-92141 Clamart, France 'TRANSPLANT PROC 1986 18 (5) S4, 83 Nature and origin of Grn immunologic alteration Camussi i://State Univ New YorK. Sr'h Med, Dept Pathol b Microbial, Buffalo, NY 14214, USA TRANSPLANT PROC 1986 18 (51 54, "! *l;lt,,!rt ~qcrivarini Fnrti~r wi allogrili: reject ii317

Coffma" TM, Schwertschlag U, Yarger WE, Pfrotaky E, Benveniste J, Klotman PE*f/*Vet Adm Med Ctr, Rm B3002, 508 Fulton St, Durham, NC 27705, USA TRANSPLANT PROC 1986 g (5) S4, 94 Lipid mediators in acute renal allograft rejection Steinhauer HB, Wilms H, Ruther M, Schollmeyer P//U"lv Frelburg, Med Kli", Dept Internal Med, Div Nephrol Abt 4, Hugstetterstr 55, D-7800 Freiburg, W Germany TRANSPLANT PROC 1986 _?5!(5) S4, 98 Clfnical experience with urine TX82 in acute renal allograft rejection Lowry RP, Blals D, Marghesco D. Powell WS//Royal Victoria Hasp, Dept Med, Endocrine Lab, Renal Immunol Lab, 687 Pine Ave W, Montreal, Quebec, Canada H3A 1Al TRANSPLANT PROC 1986 g (5) S4, 116 Inflammatory mediators and cytotoxfns in cardiac allograft rejection: current results and ongoing studies Werder EA, Hilbe W, Vallotton MB/f Children6 Hasp, St Gallen, Swltzerland ACTA ENDOCRINOL 1986 112 (S279), 381 Prostaglandln excretion in pseudohypoaldosteronism type-1 Tannen RL. Goyal M//Univ Michigan, 3914 Taubman Ctr, Box 0364, Ann Arbor, Mi 48109, USA J LAB CLIN MED 1986,108 (4) 277 Urinary inhibitor of the ammoniagenic response to acute acldosls is a prostaglandln Prisco D. Rogasi PG, Matucci M, Abbate R, Genslni GF, Sernerl GGN// Univ Florence, Med 1 Clin, I-50121 Florence, Italy THROMB RES 1986, 2 (1) 101 Increased thromboxane A2 generation and altered membrane fatty acid composition In platelets from patients with active angina pectorls Wernse H, Tltto W, Goerig M//Univ Wuraburg, Dept Internal Med, Josef Schneider Str 2, D-8700 Wurzburg, W Germany HEPATOLOGY 1986, 5 (5) 911 Release of prostanoids into the portal and hepatlc vein in patients with chronic liver disease Ruzlcka T//Univ Munfch, Dept Dermatol, D-8000 Munich 2, W Germany BRIT J DERMATOL 1986,115 (4) 517 Arachldonic acid metabolism by polymorphonuclear leukocytes in psoriasis (Letter) Maurice PDL, Allen BR//St Johns Hasp Dis Skin, 5 Lisle St, London WC2H 7BJ, England BRIT J DERMATOL 115 (4) 518 Arachldonic acid~tabolfsm by polymorphonuclear leukocytes in psoriasis (Reply) Fiedler P, Wolkln A*, Rotrosen J//*Vet Adm Med Ctr, Psychlat Serv, 1st Ave & E 24th St, New York, NY 10010, USA

BIOL PSYCHIAT 1986, 21 (13) 1347 Niacin-induced flushas a measure of prostaglandln activity In alcoholics and schizophrenics Srivastava R, Puri V, Srimal RC, Dhawan BN//Cent Drug Res Inst, Div Eye Dis, Lucknow 226001, Uttar Pradesh, India AGENT ACTION 1986, fi (S-6) 596 Prostanoid mediated effects of centchroman, a non-steroldal oral contraceptive 14 PROSTAGLANDINS AS DRUGS Thavarasah AS, Almohdzar SA//lJnlv Sci Malaysia, Hosp, Dept Obstet & Gynecol, Per-rang, Malaysia BIOL RES PREG PERINATOL 1986, 7 (3) 106 Prostaglandin (FZalpha) in missed abortion. Intravenous, extraamniotic and intramuscular adminfstratlon-a randomlaed study Lupinettl FM, Starnes VA, Laws KA, Collins JC, Hammon JW//Vanderbilt Univ, Sch Ned, Dapt Cardiac h Thorac Surg, Nashville, Tn 37212, USA J SURG RES 1986,s (2) 146 Prostacyclln reduction of regional ischemlc Injury in the canine myocardium Hautekeete ML, Nagler JM*, Cuykens JJ, Parfsel G, Laekeman GM, Herman AG//*Middelheim Gen Hosp, Dept Internal Med, Lindendreef 1, B-2020 Antwerp, Belgium CLIN NEPHROL 1986, 26 (3) 157 6-keto-PGFlalpha levels and prostacyclin therapy in 2 adult patients with hemolytic-uremic syndrome Wiqvist I, Norstrom A, Wiqvist N//Gothenburg Univ, Sahlgrens Hosp, Dept Obstet 6 Gynecol, S-41345 Gothenburg, Sweden ACTA OBSTET GYNECOL SCAND 1986, 65 (5) 485 Induction of labor by lntra-cervical PGE2 in VISCOUS gel. Mechanism of action and clinical treatment ro"tI"es Fowler PD//Staffordshire Rheumat Ctr, Stoke on Trent, England BRIT J CLIN PRACT 1986. 2 (9) 357 Synthetic prostaglandins - have they a place in rheumatology? Segerbergkonttlnen M//Unlv Helsinki, Dept Forens Ned, Kytosuontle 11, SF-00280 Helsinki 28, Finland AMER J FOREN MED PATH 1986, I (3) 244 Maternal death due to unnoticed ectoplc pregnancy during prostaglandln-induced abortion Ohno M, Fujlta K, Shiralwa M, Iauml A, Kobayashl S, Yoshiwara H, Kudo I, Inoue K, Nojlma S//Univ Tokyo, Fat Pharmaceut Sci, Bunkyo ku, Tokyo 113, Japan J MED CHEM 1986 29 (10) 1812 Molecular design toward biologically significant compounds based on "latelet activating factor: a hlghly selective agonist as a potential antlhypertensive agent

Aked D, Foster SJ*, Howarth A, McCormick ME, Potts HC//*ICI Plc, Div Pharmaceut, Dept Bloscl 1, Alderley Pk, Macclesfleld SK10 4TG, Cheshire, England BRIT J PHARMACOL 1986, 2 (2) 431 The inflammatory response of rabbit skin to topical arachidonlc acid and its pharmacological modulation Braquet P, Vargaftlg BB//Inst Henrl Beaufour, Res Labs, 17 Ave Descartes, F-92350 Le Plessls, France TRANSPLANT PROC 1986 &3 (5) S4. 10 Pharmacology of platelet activating factor Aria S, Billingham ME, Jamleso" SW//Stanford Univ, Med Ctr, Dapt Cardlovasc Surg, Stanford, Ca 94305, USA TRANSPLANT PROC 1986 g (5) S4, 71 Possible attenuation of graft atherosclerosis by prostaglandin E analogues Nghlem DD, Elkaki MH, Southard JH. Brubacher M, Scott D, Smith T// Allegheny Gen Hosp, Dept Surg. 320 E North Ave, Pittsburgh, Pa 15212, USA TRANSPLANT PROC 1986 g (5) S4, 113 Renal preservation of prostaglandlns and alkaline buffers: a comparative study Eddy CA, Laufe LE, Dun" RL, Gibson JW//Unfv Texas, Hlth Scl Ctr, Dept Obstet 6 Gynecol, 7703 Floyd Curl Dr, San Antonlo, TX 78284, USA PLAST RECONSTR SURG 1986, 78 (4) 504 The use of prostacyclin analoguecontaining suture for the prevention of postoperative venous thrombosis in the rat Petry JJ//221 Boston Post Rd E, Marlborough, Ma 01752, USA PLAST RECONSTR SLJRG 1986, 78 (4) 511 Disc"ss10" 15 INHIBITORS OF SYNTHESIS Clark DC, Lfnden J//Oklahoma Med Res Fdn, Cardlovasc Res Program, 825 NE 13th St, Oklahoma City, Ok 73104, USA HYPERTENSION 1986, 5 (10) 947 Modulation of guanylace cyclase by lipoxygenase lnhibltors Iwakami S, Shibuya M, Tseng C-F, Hanaoka F, Sankawa U*//*Univ Tokyo, Fat Pharmaceut Sci, 7-3-l Hongo, Bunkyo ku, Tokyo 113, Japan CHEF! PHARM BULL TOKYO 1986 24 (9) 3960 Inhibition of arachldonate 5lipoxygenase by phenolic compounds Hirata F//NIMH, Cell Biol Lab, 9000 Rockville Pike, Bethesda, Md 20892, USA TRANSPLANT PROC 1986 z (5) 54, 29 holes of lipocortln as a mediator of glucocortlcoids In the rejection of allografts Tomoda H//Tokaf Univ, Sch Med. Dept Cardiol, Isehara, Kanagawa 25911, Japan AMER HEART J 1986, 112 (4) 696

Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046) 17 ANALOGUES AND CHEMICAL SYNTHESIS Stork G, Sher PM, Chen H-L//Columbia Univ, Dept Chem, New York, NY 10027, USA J AMER CHEM SOC 1986, 108 (20) 6384 Radical cycllzation-tr=lng In the synthesis of natural products. A simple, stereocontrolled route to prostaglandin FZalpha Guzzi U, Ciabatti R*, Padova C, Battaglla F, Cellentani M, Depaoli A, Gallianl G, Schiatti P, Spina G//*Grp Lepetit Spa Res Labs, Via Durando 38, Milano, Italy J MED CHEM 1986 29 (10) 1826 Structure-activity studies of 16-methoxy-lb-methyl prostaglandins

18 TECHNIQUES Tomori E. Cseh G. Varzek M//Lnst Drug Res, POB 82, H-1325 Budapest, Hungary J CHROMATOGR 1986, -365 (SEP) 16i Sensitive method for the determinatlon of 6-oxo-prostaglandin Flalpha by gas chromatography with electroncapture and mass-fragmentographic detection Leis HJ, Malle E, Moser R, Nlmpf J, Kostner GM, Esterbauer H, Gleispach H//Graz Univ, Kinderklln, Mass Spektrometrle Abt, Auenbruggerpl 20, A-8036 Graz, Austria BIOMED ENVIRON MASS SPECTROM 1986, 1;? (9) 483 Preparation of 180-labelled standards of hydroxy-eicosatetraenoic acids and thromboxanes for quantitative measurement by gas chromatography/ mass spectrometry