- Email: [email protected]
HLA-A, -B, -DQA1, -DQB1 and -DRB1 alleles in a population from Crete
911
HLA allele DRB1*1423 DRB1*1424 DRB1*1425 DRB1*1427 DRB1*1428 DRB1*1429 DRB1*1430 DRB1*1431 DRB1*15 DRB1*1505 DRB1*1601 DRB1*1602 DRB1*1603 DRB1*1604 DRB1*1605 DRB1*1607 DRB1*1608
Frequency (%) Gene frequency 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37.8 0.206 0 0 1.1 0.006 1.1 0.006 0 0 0 0 1.1 0.006 0 0 0 0
HLA haplotype
Frequency (%)
DRB1*0101-DQA1*0101-DQB1*0501 DRB1*0102-DQA1*0101-DQB1*0501 DRB1*0301-DQA1*0501-DQB1*0201 DRB1*0302-DQA1*0401-DQB1*0402 DRB1*07-DQA1*0201-DQB1*02 DRB1*0804-DQA1*0501-DQB1*0301 DRB1*0901-DQA1*0303-DQB1*02 DRB1*1001-DQA1*0105-DQB1*0501 DRB1*1101-DQA1*0102-DQB1*0602 DRB1*1101-DQB1*0602-DPB1*0101 DRB1*1102-DQA1*0505-DQB1*0301 DRB1*1201-DQA1*0105-DQB1*0501 DRB1*1302-DQA1*0102-DQB1*0501 DRB1*1302-DQA1*0102-DQB1*0609 DRB1*15-DQA1*0102-DQB1*0602 DRB1*15-DQB1*0602-DPB1*0201 DRB1*15-DQB1*0602-DPB1*0402
2.2 3.9 6.7 3.4 6.2 5.1 5.6 2.2 7.3 3.0 5.6 1.7 5.1 3.4 18.5 10.0 5.6
Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA-A, -B, -DQA1, -DQB1 and -DRB1 Alleles in a Population from Crete A. Arnaiz-Villena*, P. Iliakis, M. Gonzalez-Hevilla, J. Longas, E. Gomez-Casado, K. Sfyridaki, J. Trapaga, C. Silvera-Redondo, C. Matsouka and J. Martinez-Laso Department of Immunology, Hospital 12 de Octubre, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain E-mail: *[email protected] This population from Crete, Latitude 35N Longitude 25E, consisted of 135 Caucasian individuals. The individuals were from a rural environment and were chosen from all around the Island. Ancestors had lived there for at least three generations. HLA class I antigens were determined by a serological method and class II alleles using sequence specific oligonucleotide probes. The results have previously been published in Tissue Antigens 53, 213–226, 1999. Human Immunology 65, 911–912 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele A*01 A*02 A*03 A*11 A*23 A*24 A*25 A*26 A*29 A*30 A*31 A*32 A*33 A*68 B*07 B*08 B*13 B*14 B*15 B*18 B*27 B*35 B*37 B*38 B*39
Gene frequency 0.120 0.255 0.075 0.040 0.080 0.150 0.030 0.060 0.040 0.040 0.010 0.035 0.045 0.015 0.070 0.043 0.038 0.043 0.038 0.075 0.010 0.244 0.032 0.037 0.016 0198-8859/04/$–see front matter
912
HLA allele Gene frequency B*40 0.022 B*41 0.005 B*44 0.048 B*49 0.027 B*50 0.005 B*51 0.102 B*52 0.032 B*53 0.032 B*55 0.037 B*57 0.016 B*58 0.021 DQA1*01 0.396 DQA1*0201 0.126 DQA1*03 0.122 DQA1*0401 0.011 DQA1*0501 0.347 DQA1*0503 0.004 DQB1*02 0.200 DQB1*0301 0.271 DQB1*0302 0.092 DQB1*0303 0.008 DQB1*0304 0.004 DQB1*0305 0.004 DQB1*0401 0.004 DQB1*0402 0.008 DQB1*0501 0.130 DQB1*0502 0.100 DQB1*0503 0.045 DQB1*0601 0.030 DQB1*0602 0.037 DQB1*0603 0.033 DQB1*0604 0.030 DQB1*0605 0.004 DQB1*0606 0.004 DRB1*0101 0.066 DRB1*0102 0.014 DRB1*0104 0.004 DRB1*0301 0.074 DRB1*0401 0.007 DRB1*0402 0.051 DRB1*0403 0.033 DRB1*0404 0.011 DRB1*0405 0.019 DRB1*0701 0.111 DRB1*08 0.011 DRB1*1001 0.037 DRB1*1101 0.111 DRB1*1102 0.004 DRB1*1103 0.022 DRB1*1104 0.100 DRB1*1201 0.007 DRB1*1202 0.019 DRB1*1301 0.033 DRB1*1302 0.037 DRB1*1303 0.011 DRB1*1305 0.004 DRB1*1401 0.044 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA allele Gene frequency DRB1*1501 0.037 DRB1*1502 0.044 DRB1*1601 0.078 HLA haplotype
Frequency (%)
A*01-B*08-DRB1*0301-DQA1*0501-DQB1*02 A*23-B*35-DRB1*1101-DQA1*0501-DQB1*0301 A*24-B*35-DRB1*0101-DQA1*0101-DQB1*0501 A*26-B*35-DRB1*1601-DQA1*0102-DQB1*0502
1.1 1.1 1.1 1.5
HLA-A and -B Allele Frequencies in a Population from Croatia E. Cecuk, Z. Grubic*, K. Stingl, R. Zunec and V. Brkljacic-Kerhin National Referral Organ Transplantation and Tissue Typing Centre, University Hospital Zagreb, Zagreb, Croatia E-mail: *[email protected] This population from Croatia, Latitude 45N, Longitude 15E consisted of 150 Caucasian individuals. The individuals were drawn from an urban environment (Zagreb, capital city) but originate from all regions of Croatia as established by questionnaire. The results to be published in Proceedings of 13th International Workshop. Human Immunology 65, 912–916 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele Gene frequency A*0101 A*0102 A*0103 A*0201 A*0202 A*0203 A*0204 A*0205 A*0206 A*0207 A*0208 A*0209 A*0210 A*0211 A*0212 A*0213 A*0214 A*0215N A*0216 A*0217
0.097 0 0 0.263 0 0 0 0.007 0.003 0 0 0 0 0 0 0 0 0 0 0.003 0198-8859/04/$–see front matter
HLA allele DRB1*1423 DRB1*1424 DRB1*1425 DRB1*1427 DRB1*1428 DRB1*1429 DRB1*1430 DRB1*1431 DRB1*15 DRB1*1505 DRB1*1601 DRB1*1602 DRB1*1603 DRB1*1604 DRB1*1605 DRB1*1607 DRB1*1608
Frequency (%) Gene frequency 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37.8 0.206 0 0 1.1 0.006 1.1 0.006 0 0 0 0 1.1 0.006 0 0 0 0
HLA haplotype
Frequency (%)
DRB1*0101-DQA1*0101-DQB1*0501 DRB1*0102-DQA1*0101-DQB1*0501 DRB1*0301-DQA1*0501-DQB1*0201 DRB1*0302-DQA1*0401-DQB1*0402 DRB1*07-DQA1*0201-DQB1*02 DRB1*0804-DQA1*0501-DQB1*0301 DRB1*0901-DQA1*0303-DQB1*02 DRB1*1001-DQA1*0105-DQB1*0501 DRB1*1101-DQA1*0102-DQB1*0602 DRB1*1101-DQB1*0602-DPB1*0101 DRB1*1102-DQA1*0505-DQB1*0301 DRB1*1201-DQA1*0105-DQB1*0501 DRB1*1302-DQA1*0102-DQB1*0501 DRB1*1302-DQA1*0102-DQB1*0609 DRB1*15-DQA1*0102-DQB1*0602 DRB1*15-DQB1*0602-DPB1*0201 DRB1*15-DQB1*0602-DPB1*0402
2.2 3.9 6.7 3.4 6.2 5.1 5.6 2.2 7.3 3.0 5.6 1.7 5.1 3.4 18.5 10.0 5.6
Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA-A, -B, -DQA1, -DQB1 and -DRB1 Alleles in a Population from Crete A. Arnaiz-Villena*, P. Iliakis, M. Gonzalez-Hevilla, J. Longas, E. Gomez-Casado, K. Sfyridaki, J. Trapaga, C. Silvera-Redondo, C. Matsouka and J. Martinez-Laso Department of Immunology, Hospital 12 de Octubre, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain E-mail: *[email protected] This population from Crete, Latitude 35N Longitude 25E, consisted of 135 Caucasian individuals. The individuals were from a rural environment and were chosen from all around the Island. Ancestors had lived there for at least three generations. HLA class I antigens were determined by a serological method and class II alleles using sequence specific oligonucleotide probes. The results have previously been published in Tissue Antigens 53, 213–226, 1999. Human Immunology 65, 911–912 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele A*01 A*02 A*03 A*11 A*23 A*24 A*25 A*26 A*29 A*30 A*31 A*32 A*33 A*68 B*07 B*08 B*13 B*14 B*15 B*18 B*27 B*35 B*37 B*38 B*39
Gene frequency 0.120 0.255 0.075 0.040 0.080 0.150 0.030 0.060 0.040 0.040 0.010 0.035 0.045 0.015 0.070 0.043 0.038 0.043 0.038 0.075 0.010 0.244 0.032 0.037 0.016 0198-8859/04/$–see front matter
912
HLA allele Gene frequency B*40 0.022 B*41 0.005 B*44 0.048 B*49 0.027 B*50 0.005 B*51 0.102 B*52 0.032 B*53 0.032 B*55 0.037 B*57 0.016 B*58 0.021 DQA1*01 0.396 DQA1*0201 0.126 DQA1*03 0.122 DQA1*0401 0.011 DQA1*0501 0.347 DQA1*0503 0.004 DQB1*02 0.200 DQB1*0301 0.271 DQB1*0302 0.092 DQB1*0303 0.008 DQB1*0304 0.004 DQB1*0305 0.004 DQB1*0401 0.004 DQB1*0402 0.008 DQB1*0501 0.130 DQB1*0502 0.100 DQB1*0503 0.045 DQB1*0601 0.030 DQB1*0602 0.037 DQB1*0603 0.033 DQB1*0604 0.030 DQB1*0605 0.004 DQB1*0606 0.004 DRB1*0101 0.066 DRB1*0102 0.014 DRB1*0104 0.004 DRB1*0301 0.074 DRB1*0401 0.007 DRB1*0402 0.051 DRB1*0403 0.033 DRB1*0404 0.011 DRB1*0405 0.019 DRB1*0701 0.111 DRB1*08 0.011 DRB1*1001 0.037 DRB1*1101 0.111 DRB1*1102 0.004 DRB1*1103 0.022 DRB1*1104 0.100 DRB1*1201 0.007 DRB1*1202 0.019 DRB1*1301 0.033 DRB1*1302 0.037 DRB1*1303 0.011 DRB1*1305 0.004 DRB1*1401 0.044 Human Immunology 65 (2004) © American Society for Histocompatibility and Immunogenetics, 2004 Published by Elsevier Inc.
HLA allele Gene frequency DRB1*1501 0.037 DRB1*1502 0.044 DRB1*1601 0.078 HLA haplotype
Frequency (%)
A*01-B*08-DRB1*0301-DQA1*0501-DQB1*02 A*23-B*35-DRB1*1101-DQA1*0501-DQB1*0301 A*24-B*35-DRB1*0101-DQA1*0101-DQB1*0501 A*26-B*35-DRB1*1601-DQA1*0102-DQB1*0502
1.1 1.1 1.1 1.5
HLA-A and -B Allele Frequencies in a Population from Croatia E. Cecuk, Z. Grubic*, K. Stingl, R. Zunec and V. Brkljacic-Kerhin National Referral Organ Transplantation and Tissue Typing Centre, University Hospital Zagreb, Zagreb, Croatia E-mail: *[email protected] This population from Croatia, Latitude 45N, Longitude 15E consisted of 150 Caucasian individuals. The individuals were drawn from an urban environment (Zagreb, capital city) but originate from all regions of Croatia as established by questionnaire. The results to be published in Proceedings of 13th International Workshop. Human Immunology 65, 912–916 (2004). © American Society for Histocompatibility and Immunogenetics, 2004. Published by Elsevier Inc. HLA allele Gene frequency A*0101 A*0102 A*0103 A*0201 A*0202 A*0203 A*0204 A*0205 A*0206 A*0207 A*0208 A*0209 A*0210 A*0211 A*0212 A*0213 A*0214 A*0215N A*0216 A*0217
0.097 0 0 0.263 0 0 0 0.007 0.003 0 0 0 0 0 0 0 0 0 0 0.003 0198-8859/04/$–see front matter