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5480895 Method of producing antibodies to a restricted population of T lymphocytes, antibodies produced therefrom and methods of use thereof
PATENT ABSTRACTS
accumulation of sterols in yeast comprising increasing the expression level of a structural gene encoding a polypeptide having Deltas-7 sterol isomerase activity in a mutant yeast having single or double defects in the expression of sterol biosynthetic enzymes is provided.
5480864 MODIFIED MAXADILAN PROTEIN, ITS PREPARATION AND USE, AND DNA ENCODING THE PROTEIN Tajima Masahiro; Ohnuma Manami; Lerner Ethan L Yokohama, JAPAN assigned to Shiseido Co Ltd; The General Hospital A modified maxadilan protein exhibits higher biological activity than native maxadilan from the sand fly Lutzomyia longipalpis. A modified maxadilan fusion protein contains a thrombin cleavage site. This enables the production of the modified maxadilan as a fusion protein and recovery of the modified maxadilan after digestion with thrombin. The modified maxadilan is a potent vasodilator.
5480895 METHOD OF PRODUCING ANTIBODIES TO A RESTRICTED POPULATION OF T LYMPHOCYTES, ANTIBODIES PRODUCED THEREFROM AND METHODS OF USE THEREOF Friedman Steven M; Crow Mary K; Posnett David Tenafly, NJ, UNITED STATES assigned to New York Society for the Relief of the Ruptured and Crippled Maintaining the Hospital for Special Surgery This invention relates to a method of obtaining antibodies specific to a population of T-lymphocytes (T cells) restricted by V
10.5
beta gene usage. The invention also relates to the antibodies obtained and to methods of using them. According to the invention, T cells are incubated with an effective amount of a superantigen under conditions and for a time sufficient to allow division and growth of T-cells reactive to the superantigen. The incubated T-cells are injected into a mammal, and thereafter serum containing antibodies specific to the incubated and injected T-cells is removed from the mammal.
5480956 FELINE INTERFERON AND PROCESS FOR PRODUCTION THEREOF Yanai Akira; Ueda Yoshizum; Sakurai Toru; Satoh Masahir Kamakum JAPAN assigned to Toray Industries Inc A recombinant silkworm nuclear polyhedrosis virus containing DNA coding for a protein of feline interferon; the recombinant virus is constructed by cotransfection a recombinant plasmid having a gene coding for a protein of feline interferon and a silkworm nuclear polyhedrosis virus DNA into established silkworm cells, and cloning the desired recombinant virus. The recombinant virus is useful for a mass-production of feline interferon.
5480968 ISOLATED POLYPEPTIDE ERBB-3, RELATED TO THE EPIDERMAL GROWTH FACTOR RECEPTOR AND ANTIBODY THERETO Kraus Matthias; Aaronson Stuart A Bethesda, MD, UNITED STATES assigned
accumulation of sterols in yeast comprising increasing the expression level of a structural gene encoding a polypeptide having Deltas-7 sterol isomerase activity in a mutant yeast having single or double defects in the expression of sterol biosynthetic enzymes is provided.
5480864 MODIFIED MAXADILAN PROTEIN, ITS PREPARATION AND USE, AND DNA ENCODING THE PROTEIN Tajima Masahiro; Ohnuma Manami; Lerner Ethan L Yokohama, JAPAN assigned to Shiseido Co Ltd; The General Hospital A modified maxadilan protein exhibits higher biological activity than native maxadilan from the sand fly Lutzomyia longipalpis. A modified maxadilan fusion protein contains a thrombin cleavage site. This enables the production of the modified maxadilan as a fusion protein and recovery of the modified maxadilan after digestion with thrombin. The modified maxadilan is a potent vasodilator.
5480895 METHOD OF PRODUCING ANTIBODIES TO A RESTRICTED POPULATION OF T LYMPHOCYTES, ANTIBODIES PRODUCED THEREFROM AND METHODS OF USE THEREOF Friedman Steven M; Crow Mary K; Posnett David Tenafly, NJ, UNITED STATES assigned to New York Society for the Relief of the Ruptured and Crippled Maintaining the Hospital for Special Surgery This invention relates to a method of obtaining antibodies specific to a population of T-lymphocytes (T cells) restricted by V
10.5
beta gene usage. The invention also relates to the antibodies obtained and to methods of using them. According to the invention, T cells are incubated with an effective amount of a superantigen under conditions and for a time sufficient to allow division and growth of T-cells reactive to the superantigen. The incubated T-cells are injected into a mammal, and thereafter serum containing antibodies specific to the incubated and injected T-cells is removed from the mammal.
5480956 FELINE INTERFERON AND PROCESS FOR PRODUCTION THEREOF Yanai Akira; Ueda Yoshizum; Sakurai Toru; Satoh Masahir Kamakum JAPAN assigned to Toray Industries Inc A recombinant silkworm nuclear polyhedrosis virus containing DNA coding for a protein of feline interferon; the recombinant virus is constructed by cotransfection a recombinant plasmid having a gene coding for a protein of feline interferon and a silkworm nuclear polyhedrosis virus DNA into established silkworm cells, and cloning the desired recombinant virus. The recombinant virus is useful for a mass-production of feline interferon.
5480968 ISOLATED POLYPEPTIDE ERBB-3, RELATED TO THE EPIDERMAL GROWTH FACTOR RECEPTOR AND ANTIBODY THERETO Kraus Matthias; Aaronson Stuart A Bethesda, MD, UNITED STATES assigned