518
JOURNAL O F THE
AMERICAN PHARMACEUTICAL ASSOCIATION
vol. XLIV, No. 8
SUMMARY
sirably low intensity. Observation of the ampuls degraded a t higher temperatures had shown that an absorbance of the extract of At = 0.225 should be deemed undesirable. The predicted times of this estimated point of rejection are given for several temperatures in Table IV.
1. A Drocedure for mediction of shelf stability of a component in a complex pharmaceu. tical preparation is outlined and applied to stability of a liquid multisulfa preparation. yellow No. 'j and DC Red. No. 33 TABLE IV.-DURATION OF COLOR(CORRESPONDING 2. FD TO ESTIMATED POINT OF REJECTION OF ABSORBANCEwere used t o impart pink coloration t o a liquid OF EXTRACT, A t = 0.225) multisulfa preparation and were found t o meet the specification of the year's room temperature 20" 887 days (ca. 2 l / 2 yrs.) stability by a study t h a t took no longer than four 25" 488 days (ca. 11/3yrs.) 30" 281 days (ca. 3/4 yr.) weeks.
If an arbitrary color stability period of one year a t room temperature is specified, the studied preparation may be accepted as meeting this sperification.
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REFERENCE
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Book Notices This is Liquid Sugar. A Technical Guide for the Liquid Sugar User. Refined Syrups & Sugars, Inc., Yonkers, New York, 1955. VII 205 pp. 15.5 x 23 cm. A monograph on "liquid sugar" describing production, testing, properties, and commercial applications of the generally saturated aqueous solutions of sugar (sucrose, invert, or mixtures of both). "Syrup" is often used synonymously with "liquid sugar," but they are distinguished industrially by the U. S. Sugar Act definition of a liquid sugar as a solution containing less than six per cent soluble nonsugar solids. Technical data on specific gravity, density equivalents, turbidity, alteration of concentration, determinatioh of saturation relations of sucrose, invert sugar and water, viscosity and boiling points, are tabulated in the appendix.
+
Particularly useful is the appendix which contains the names of various sources of supply for the material needed in the preparation of the various formulas listed. This book deserves a place on the shelves of every drug store.
Pharmazeutisches Worterbuch. By CURTHUNNIUS. Walter de Gruyter & Co., Berlin, 1955. xi f 610 pp. 14 x 19.5 cm. Price DM 18.50.
This second edition of Hunnius' dictionary has been considerably increased in contents and volume over the first one. The more than one hundred additional pages have been used partly to supply additional material on topics previously discussed and partly to bring the book up to date by including the latest developments in the field of pharmacy. A happy medium has been found between short defiNew Practical Formulary. By MITCHELLFREEMAN, nitions covering very specific topics and articles runChemical Publishing Company, Inc., New York, ning to as many as three pages discussing larger 1955. 376 pp. 14 x 21.5 cm. Price $7 95. ones in such a way as t o serve as an introduction This is an eminently practical book which con- to the uninitiated. Among the new tables included, tains in just one volume useful information in such we find indicators, the numbers of organic ring comvaried fields as agricultural specialties; animal prep- pounds, doses for infants and children, and the viarations; cements, glues, mucilages; cosmetics, per- tamin contents of certain foods. Particular attenfumes; disinfectants; insect and rodent destroy- tion may also be called to the table of biological units ers; pharmaceutical and proprietary preparations ; which was contained in the iirst issue and as far as and stain removers. Earlier books in this same field we know has no counterpart in English. For everyhave been less concise and sometimes ran into sev- body who has t o deal with pharmaceutical material eral volumes, whereas Mr. Freeman seems t o be this book is indispensable. It shows the remarkable able to present a cornucopia of useful up-to-date comeback which Germany has made in the field of pharmacy. illformation in one handy volume.
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