Title section, list of contents author and subject index volume 20 (1992)

NEUROCHEMISTRY INTERNATIONAL The Journal f o r the publication of cellular and molecular aspects of neurochemistry in the f o r m of original and rapid research c o m m u n i c a t i o n s and also critical reviews and commentaries

Title Section, List of Contents

Author and Subject Index Volume 20 (1992)

PERGAMON PRESS Oxford

• New

York

• Seoul

• Tokyo

NEUROCHEMISTRY INTERNATIONAL The Journal for the publication of cellular and molecular aspects of neuroehemistry in the form of original and rapid research communications and also critical reviews and commentaries Executive Editors For U.K. Also lbr Reviews, Commentaries and Rapid Papers N. N. O s b o r n e ( C h a i r m a n ) : Nuffield Laboratory o f Ophthalmology, University o f Oxjbrd,

Walton Street, Oxford O X 2 6A W, U.K. For Europe and Africa: J. Rossier: lnstitut A Fessard, CNRS,

F o r The Americas: W. Lovenberg: Marion Merrell Dow Research

91198 G(f-sur- Yvette, France

Institute. 2110 East Galbraith Road. Cincinnati, OH 45215, U.S.A N. H. Neff: Department of Pharmacology, Ohio State University College of Medicine, 333W lOth Avenue, Columbus, OH 43210, U.S.A. R. Tapia: lnstituto de Fisiologia Celular, Universidad Nacional Autonoma, AP 70-600, 04510 Mexico D.F.. Mexico

F o r Asia:

K. Kuriyama: Department of Pharmacology, Kyoto Pre[ectural University of Medicine, KawaramachiHirokoji, Kamikyo-ku, Kyoto, Japan For Australasia:

G. A. R. Johnston: Department oJ Pharmacology, University of Sydney, Sydney, NS W 2006, Australia

Editorial Advisor)' Board L. F. Agnati, Modena T. Barffai, Stockholm J. G. C. Boekaert, Montpellier J.-M. Bourre, Paris H. Breer, Stuttgart S. H. Buck, Cincinnati, OH R. D. Burgoyne, Liverpool, U.K A. P. Carvalho, Coimbra M. Ebadi, Omaha, NE M. Fillenz, OxJord, U.K R. W. Fuller, Indianapolis, IN K. G. Fuxe, Stockholm M. Hadjiconstantinou, Columbus, OH M. Hamon, Paris R. J. Huxtable, Tucson, AZ P. M. luvone, Atlanta, GA D. M. Jacobowitz, Bethesda, MD G. Jaim-Etcheverry, Buenos Aires

B. Jarrott, Clayton. Victoria G. Kapatos, Detroit, MI J. E. Kralme, St Louis, MO D. M. Kuhn, Detroit, M1 P. J. Magistretti, Lausanne M. H. Makman, New York. N Y N. Miki, Osaka N. Morel, G([Zsur-Yvette A. H. Mulder, Amsterdam T. Nagatsu, Nagoya D. G. Nicholls, Dundee, U.K B. Oderfeld-Nowak, Warsaw S. E. Podusio, Lubbock. TX J. F. Pujol, Lyon M. Raiteri, Genoa T. A. Reader, Montrka/ M. Recasens, Montpellier P. J. Richardson, Cambridge. U.K.

S. Rose, Milton Keynes, U.K. R. H. Roth, New Haven, CT E. Sanders-Bush, Nashville, TN A. Sehousboe, Copenhagen J. P. Schwartz, Bethesda, MD R. Tanaka, Nagoya V. I. Teiehherg, Rehovot G. Tettamanti, Milan G. Toffano, Abano Terme K. Uyemura, Tokyo J.-J. Vanderhaeghen, Brussels G. Vauquelin, Sint Genesius-Rode E. S. Vizi, Budapest G. P. Wilkin, London. U.K. J.-Y. Wu, Lawrence, KS H. Zimmermann, Frank[urt am Main

C o p y r i g h t O 1992 P e r g a m o n P r e s s L t d Published 8 issues/annum (in 2 volumes) in January, February, April, June, July, September, October and December.

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LIST OF CONTENTS VOLUME 20 (1992) Number 1 Jorge Hern~indez-R.

1

Invited Review: Na+/K+-ATPase regulation by neurotransmitters

E. S. Vizi and F. Oberfrank

11

Critique: Na+/K+-ATPase, its endogenous ligands and neurotransmitter release

J. W. Phillis

19

Critique: Na+/K+-ATPase as an effector ofsynaptic transmission

Jolanta B. Zawilska and Jerzy Z. Nowak

23

Commentary: Regulatory mechanisms in melatonin biosynthesis in retina

Ray W. Fuller, Susan K. Hemrick-Luecke and John S. Ward

37

Potent in vivo but not in vitro inhibition of monoamine oxidase by 3-chloro- ct-phenylpyrazinemethanol

M. J. Neal, J. R. Cunningham, P. H. Hutson and J. E. Semark

43

Calcium dependent release of acetylcholine and "f-aminobutyric acid from the rabbit retina

A. Henkel and H. Zimmermann

55

In vitro binding of isolated synaptic vesicles to presynaptic plasma membranes: activation by Ca 2÷ and protein kinase C

Tatsuo Suzuki, Sumiko Abe-Dohmae and Ryo Tanaka

61

P,~.proteinisoneofthemajorsubstratesforCa-~÷calmodulin-dependent protein kinase II in the postsynaptic density-enriched fraction isolated from rat cerebral cortex, hippocampus and cerebellum

V. K. Saxena, P. Partoens, J. de Block, E. P. Coen, G. Vauquelin and W. P. De Potter

69

Inhibition of evoked neurotransmitter release from rat hippocampus by a polypeptide toxin isolated from the marine snail Conus distans

S. P. Butcher, D. Cameron, L. Kendall

75

Homocysteine-induced alterations in extracellular amino acids in rat hippocampus

Virendra B. Singh, Tam Hao-Phan, Karl C. Corley and Margaret C. Boadle-Biber

81

Increase in cortical and midbrain tryptophan hydroxylase activity by intracerebroventricular administration of corticotropin releasing factor: block by adrenalectomy, by RU 38486 and by bilateral lesions to the central nucleus of the amygdala

A. Pasi, P. Mehraein, A. Jehle, M. Traub, G. Morniroli, W. B~irand N. Kopp

93

fl-Endorphin: regional levels profile in the brain of the human infant

A. Coquerel, M. Buser, J. Tayot, F. Pfaff, F. Matray and B. Proust

97

Beta-endorphin and neurotensin in brainstem and cerebrospinal fluid in the Sudden Infant Death Syndrome

103

Control of breathing by endogenous opioid peptides: possible involvement in Sudden Infant Death Syndrome

Paul Schweitzer, Gilles Fortin, Jean-Claude Beloeil and Jean Champagnat

109

In vitro study of newborn rat brain maturation: implication for Sudden

F. Chigr, D. Jordan, M. Najimi, L. Denoroy, A. Sarrieau, A. de Broca, W. Rostene, J. Epelbaum and N. Kopp

113

Quantitative autoradiographic study of somatostatin and neurotensm binding sites in medulla oblongata of SIDS

Madhu Kalia

119

Early ontogeny of the vagus nerve: an analysis of the medulla oblongata and cervical spinal cord of the postnatal rat

and R. Griffiths

M. P. Morin-Surun, E. Boudinot, M. C. Fournie-Zaluski, J. Champagnat,

B. P. Roques and M. Denavit-Saubie

Infant Death Syndrome

iii

iv Eleni Dicou

Index 129

A Rapid Publication: Expression of recombinant human nerve growth factor in Escherichia coil

135

Book Reviews

137

News Items

Number 2 I

Editorial

M. B. A. Djamgoz and H.-J. Wagner

139

Invited Review: Localization and function of dopamine in the adult vertebrate retina

Joseph C. Besharse and P. Michael luvone

193

Critique: Is dopamine a light-adaptive or a dark-adaptive modulator in retina?

Dai-Eun Sok, Yun-Bae Kim, Seung-Hee Cha and Yun-Su Chung

201

Effect of choline esters on the decarbamylation of dimethylcarbamylacetylcholinesterase

Anja Garritsen, Margot W. Beukers, Ad P. ljzerman, Edward J. Cragoe Jr and Willem Soudijn

207

The mode of interaction of amiloride and some of its analogues with the adenosine A~ receptor

Philippe Bertrand, Olivier Roger, R+mi Houlgatte, France Javoy-Agid, Jean-Philippe Brandel, Adam Doble and Jean-Charles Blanchard

215

Measurement of nerve growth factor-like immunoreactivity in human brain using an anti-mouse-NGF enzyme immunoassay

Zipora Pittel, Eliahu Heldman, Rachel Rubinstein and Sasson Cohen

219

Inhibition of choline effiux results in enhanced acetylcholine synthesis and release in the guinea-pig corticocerebral synaptosomes

Kyoji Morita, Kazuhiko Teraoka, Motoo Oka and Shuichi Hamano

229

Further studies on the relationship between tyrosine supply and catecholamine production in cultured adrenal chromaffin cells

Diana Jerusalinsky, Carlos Cervefiansky, Clara Pefia, Sonia Raskovsky and Federico Dajas

237

Two polypeptides from Dendroaspis angusticeps venom selectively inhibit the binding of central muscarinic cholinergic receptor ligands

Elizabeth S. Lapadula, Daniel M. Lapadula and Mohamed B. Abou-Donia

247

Biochemical changes in sciatic nerve of hens treated with tri-o-cresyl phosphate: increased phosphorylation ofcytoskeletal proteins

Maria Clara Gravielle, Vladimir Flores and Sara Fiszer d e Plazas

257

The postnatal development of benzodiazepine receptor sites in the chick optic lobe is modulated by environmental lighting

J. M. Pocock, V. J. Venema and M. E. Adams

263

m-Agatoxins differentially block calcium channels in locust, chick and rat synaptosomes

271

Book Review

273

News Items

Index

v

Number 3 Erwin Tareilus and Heinz Breer

275

Rapid kinetics of depolarization-induced changes in intrasynaptosomal calcium concentrations

A. M. Duchemin, K. P. Gudehithlu, N. H. Neffand M. Hadjiconstantinou

281

c-lbs mRNA in mouse brain after MPTP treatment

D. Maysinger, B. R. Leavitt, B. Zorc, !. Butula, L. G. Fernandes and A. Ribeiro-da-Silva

289

Inhibition of high affinity choline uptake in the rat brain by neurotoxins: effect of monosialoganglioside GM 1

Hitoshi Aoshima, Yuichi Inoue and Daisuke Tanaka

299

A minimal model to account for the response of N-methyl-o-aspartate receptors expressed in Xenopus oocyte injected with rat brain mRNA

Alison M. McDermott, Stephen L. Dickinson 307 and Graham P. Wilkin

Thyrotropin releasing hormone (TRH) and a degradation stabilized analogue (RX77368) stimulate phosphoinositide turnover in cultured astrocytes in a regionally specific manner

Sandro Sonnino, Vanna Chigorno, Manuela Valsecchi, Marina Pitto and Guido Tettamanti

315

Specific ganglioside-cell protein interactions: a study performed with GM1 ganglioside derivative containing photoactivable azide and rat cerebellar granule cells in culture

Hinrich Rahmann, Florian Schifferer and Heinz Beitinger

323

Calcium ganglioside interactions and synaptic plasticity: effect of calcium on specific ganglioside/peptide (valinomycin, gramicidin A)complexes in mixed mono- and bilayers

H. R6sner, M. AI-Aqtum and H. Rahmann

339

Gangliosides and neuronal differentiation

A. Ben Younes-Chennoufi, V. Meininger, J. M. L6ger, P. Bouche, M. O. Jauberteau and N. Baumann

353

Antiganglioside antibodies in motor-neuron diseases and peripheral neuropathies: study by ELISA technique and immunodetection.on thinlayer chromatography

P. Bellato, F. Milan, E. Facchinetti and G. Toffano

359

Disposition of exogenous tritium-labelled GM~lactone in the rat

O. B. Karpova, V. A. Zinserling and N. F. Avrova

365

Study of brain and vascular plexus gangliosides in meningoencephalites of various etiology

H. Rahmann, H. R6sner, U. Sonnentag and S. Esders

371

Gangliosides and regeneration of the goldfish optic nerve in vivo and in

Christoph Berndt, Brigitte Brux, Andreas Lun and Johann Gross

385

Lasting effects of postnatal hypoxia and saline injection on the stfiatal dopamine transport and their modification by gangliosides

SIobodan Vukicevic, Ivica Kracun, Zeljka Vukelic, Burkhard Krempien, Harald Rosner and Cedomir Cosovic

391

24R, 25-dihydroxyvitamin D3 prevents aluminum-induced alteration of brain gangliosides in uremic rats by keeping the metal within periv.ascular astrocytes of the blood-brain barrier

Vladimir A. Tyurin, Yulia Yu. Tyurina and Natalia F. Avrova

401

Ganglioside-dependent factor, inhibiting lipid peroxidation in rat brain synaptosomes

H. R6sner, M. AI-Aqtum, U. Sonnentag, A. Wurster and H. Rahmann

409

Cell surface distribution of endogenous and effects of exogenous gangliosides on neuronal survival, cell shape and growth in vitro

Ivica Kracun, Harald Rosner, Valerija Drnovsek, Zeljka Vukelic, Cedomir Cosovic, Milica Trbojevic-Cepe and Milovan Kubat

421

Gangliosides in the human brain development and aging

lvica Kracun, Svjetlana Kalanj, Jasna Talan-Hranilovic and Cedomir Cosovic

433

Cortical distribution ofgangliosides in Alzheimer's disease

439

News Items

vitro

Index

vi N um bet 4 Clive R. Bramham

441

Invited Review: Opioid receptor dependent long-term potentiation: peptidergic regulation of synaptic plasticity in the hippocampus

John J. Wagner and Charles Chavkin

457

Critique: Endogenous opioids and LTP: another view

Daniel Johnston

461

Critique: NMDA-receptor independent LTP

Li-Yen Mae Huang

463

Critique: The excitatory effects of opioids

Laurenl Aniksztejn and Ychezkel Bcn-Ari

469

Critique: Opioid peptides and long-term potentiation

K. M. Boje, P. Skolnick, J. Raber, R. T. Fletcher and G. Chader

473

Strychnine-insensitive glycine receptors in embryonic chick retina: characteristics and modulation of N M D A neurotoxicity

G. Gupta, M. Azam and N. Z. Baquer

487

Modulation of rat brain insulin receptor kinase activity in diabetes

Jin-ichi Ito. Taiji Kato and Ryo Tanaka

493

Interaction of sialosyl cholesterol with the cell surface of rat astrocytes and its biological activities

Jack C. Brooks and Melinda H. Brooks

501

Thiophosphorylated proteins in chromaffin cells are chromaffin vesicle matrix proteins

Jack C. Brooks, Melinda H. Brooks and Stephen W. Carmichael

511

Inorganic thiophosphate effects on chromaffin cell structure and function

Hugo D. Lacorazza, Marcela S. Otero de Bengtsson and Mirtha Biscoglio de Jim+nez Bonino

521

Role of histidine residues in the ~-bungarotoxin binding site of the nicotonic acetylcholine receptor

C. Simon, P. Portalier, M. C. Chamoin and J. P. Ternaux

529

Substance P like-immunoreactivity release from enterochromaffin cells of rat caecum mucosa. Inhibition by serotonin and calcium-free medium

Shigeru Mitsuka, Mirko Diksic, A. Takada and Y. Lucas Y a m a m o t o

537

Influence of the tumor mass on the vatine rate constants and on valine incorporation into proteins in an experimental brain tumor model

S. Chaki, M. Muramatsu. Y. Ushiyama and S. Otomo

553

Purification and partial characterization of K • channel blockers from the venom of Dendroaspisangusticeps

B. V. Ravi K u m a r and P. S. ~;astry

559

Doparnine receptors in h u m a n foetal brains: characterization, regulation and ontogeny of[~H]spiperone binding sites in striatum

Niels Westergaard, Orla M. Larsson, Bente Jensen and Arne Schousboe

567

Synthesis and release of G A B A in cerebral cortical neurons co-cultured with astrocytes from cerebral cortex or cerebellum

B. Miserez, J. De Block, R. Cortvrindt. E. Van Marck and W. P. De Potter

577

Preparation of noradrenaline-storing organelles from bovine sympathetic ganglia: biochemical and morphological evaluation of partly purified large dense cored vesicles

Mizuo Takashima, Masatoshi Takita, Asami Umino, Toru Nishikawa, Hiroshi Mitsushio and Kiyohisa Takahashi

583

Modulation of cerebral acetylcholinc metabolism by the dorsal diencephalic conduction system in the rat

Patricia G. Schneider, Elena Girardi and Georgina Rodriguez de Lores Arnaiz

59t

3-Mercaptopropionic acid administration increases the affinity of ['Hiquinuclidinyl benzilatc binding to membranes of the striatum and cerebellum

599

News hems

Index

vii

VOL. 20 SUPPLEMENT

Dopaminergic Systems and their Regulation--Satellite Meeting of the Xlth International Congress of Pharmacology was p r o d u c e d as a supplement to the j o u r n a l during 1992. It was supplied to all subscribers in M a r c h 1992.

AUTHOR

Abe-Dohmae, S., 61 Abou-Donia, M. B., 247 Adams, M. E., 263 A1-Aqtum, M., 339, 409 Aniksztejn, L., 469 Aoshima, H., 299 Avrova, N. F., 365,401 Azam, M., 487 Baquer, N. Z., 487 B~ir, W., 93 Baumann, N., 353 Beitinger, H., 323 BeUato, P., 359 Beloeil, J.-C., 109 Ben-Ari, Y., 469 de Bengtsson, M. S. O., 521 Bemdt, C., 385 Bertrand, P., 215 Besharse, J. C., 201 Beukers, M. W., 207 Blanchard, J.-C., 215 de Block, J., 69,577 Boadel-Biber, M. C., Boje, K. M., 473 Bouche, P., 353 Boudinot, E., 103 Bramham, C. R., 441 Brandel, J.-P., 215 Breer, H., 275 de Broca, A., 113 Brooks, J. C., 501, 511 Brooks, M. H., 501,511 Brux, B., 385 Buser, M., 97 Butcher, S. P., 75 Butula, I., 289 Cameron, D., 75 Carmichael, S. W., 511 Cervefiansky, C., 237 Cha, S.-H., 201 Chader, G., 473 Chaki, S., 553 Chamoin, M. C., 529 Champagnat, J., 103, 109 Chavkin, C., 457 Chigorno, V., 315 Chigr, F., 113 Chung, Y.-S., 201 Coen, E. P., 69 Cohen, S., 219 Coquerel, A., 97 Corley, K. C., 81 Cortvrindt, R., 577 Cosovic, C., 391,421,433 Cragoe, Jr. E. J., 207 Cunningham, J. R., 43 Dajas, F., 237 De Potter, W. P., 69, 577 Denavit-Saubie, M., 103 Denoroy, L., 113 Dickinson, S. L., 307

INDEX

Dicou, E., 129 Diksic, M., 537 Djamgoz, M. B. A., 139 Doble, A., 215 Dmovsek, V., 421 Duchemin, A. M., 281

Lapadula, E. S., 247 Larsson, O. M., 567 Leavitt, B. R., 289 L6ger, 353 de Lores Arnaiz, G. R., 591 Lun, A., 385

Epelbaum, J., 113 Esders, S., 371

Matray, F., 97 Maysinger, D., 289 McDermott, A. M., 307 Mehraein, P., 93 Meininger, V., 353 Milan, F., 359 Miserez, B., 577 Mitsuka, S., 537 Mitsushio, H., 583 Morin-Surun, M. P., 103 Morita, K., 229 Morniroli, G., 93 Muramatsu, M., 553

Facchinetti, E., 359 Fernandes, L. G., 289 Fletcher, R. T., 473 Flores, V., 257 Fortin, G., 109 Foumie-Zaluski, M. C., 103 Fuller, R. W., 37 Garritsen, A., 207 Girardi, E., 591 Gravielle, M. C., 257 Griffiths, R., 75 Gross, J., 385 Gudehithlu, K. P., 281 Gupta, G., 487 Hadjiconstantinou, M., 281 Hamano, S., 229 Hao-Phan, T., 81 Heldman, E., 219 Hemrick-Luecke, S. K., 37 Henkel, A., 55 Hernandez-R., J., 1 Houlgatte, R., 215 Huang, L.-Y. M., 463 Hutson, P. H., 43 Ijzerman, Ad P., 207 Inoue, Y., 299 Ito, J.-i., 493 luvone, P. M., 193 Jauberteau, M. O., 353 Javoy-Agid, F., 215 Jehle, A., 93 Jensen, B., 567 Jerusalinski, D., 237 de Jim6nez Bonino, M. B., 521 Johnston, D., 461 Jordan, D., 113 Kalanj, S., 433 Kalia, M., 119 Karpova, O. B., 365 Kato, T., 493 Kendall, L., 75 Kim, Y.-B., 201 Kopp, N., 93, 113 Kracun, I., 391,421,433 Krempien, B., 391 Kubat, M., 421 Kumar, B. V. R., 559 Lacorazza, H. D., 521 Lapadula. D. M., 247 ix

Najimi, M., 113 Neal, M. J., 43 Neff, N. H., 281 Nishikawa, T., 583 Nowak, J. Z., 23 Obeffrank, F., I 1 Oka, M., 229 Otomo, S., 553 Partoens, P., 69 Pasi, A., 93 Pefia, C., 237 Pfaff, F., 97 Phillis, J. W., 19 Pittel, Z., 219 Pitto, M., 315 de Plazas, S. F., 257 Pocock, J. M., 263 Portalier, P., 529 Proust, B., 97 Raber, J., 473 Rahmann, H., 323, 339, 371. 409 Raskovsky, S., 237 Rebeiro-da-Silva, A., 289 Roger, O., 215 Roques, B. P., 103 R6sner, H.,339, 371,391, 409, 421 Rostene, W., 113 Rubinstein, R., 219 Sarrieau, A., 113 Sastry, P. S., 559 Saxena, V. K., 69 Schifferer, F., 323 Schneider, P. G., 591 Schousboe, A., 567 Schweitzer, P., 109 Semark, J. E., 43 Simon, C., 529 Singh, V. B., 81

x

Skolnick, P., 473 Sok, D.-E., 201 Sonnentag, U., 371,409 Sonnino, S., 315 Soudijn, W., 207 Suzuki, T., 61 Takada, A., 537 Takahashi, K., 583 Takashima, M., 583 Takita, M., 583 Talan-Hranilovic, J., 433 Tanaka, D., 299 Tanaka, R., 61,493 Tareilus, E., 275 Tayot, J., 97 Teraoka, K., 229

Index

Temaux, J. P., 529 Tettamanti, G., 315 Toffano, G., 359 Traub, M., 93 Trbojevic-Cepe, M., 421 Tyurin, V. A., 401 Tyurina, Y. Y., 401 Umino, A., 583 Ushiyama, Y., 553 Valsecchi, M., 315 Van Marck, E., 577 Vauquelin, G., 69 Venema, V. J., 263 Vizi, E. S., 11 Vukelic, Z., 391,421

Vukicevic, S., 391 Wagner, H.-J., 139 Wagner, J. J., 457 Ward, J. S., 37 Westergaard, O. M., 567 Wilkin, G. P., 307 Wurster, A., 409 Yamamoto, Y. L., 537 Younes-Chennoufi, A. B., 353 Zawilska, J. B., 23 Zimmermann, H., 55 Zinserling, V. A., 365 Zorc, B., 289

SUBJECT INDEX acetylcholine metabolism - in d i e n c e p h a l i c conduction s y s t e m , 583 acetylcholine synthesis - and choline efflux, 219 acetylcholine synthesis - in s y n a p t o s o m e s , 219 acetylcholine - decarboxylation, 201 acetylcholine - r e l e a s e f r o m t h e r e t i n a , 43 adenosine A 1 receptors - interaction with amiloride, 207 ~-Agatoxins - e f f e c t o n c a l c i u m c h a n n e l s in d i f f e r e n t p r e p a r a t i o n s , a g i n g of h u m a n b r a i n - e f f e c n of g a n g l i o s i d e s , 421 aluminium - influence brain gangliosides, 391 Alzheimer's disease - distribution of g a n g l i o s i d e s , 433 amiloride - e f f e c t on a d e n o s i n e A 1 r e c e p t o r s , 207 antibodies - to antigangliosides, 353 antiganglioside antibodies - in m o t o r - n e u r o n disease, 353 antiganglioside antibodies - in p e r i p h e r a l neuropathies, 353 astrocyte membranes - interaction with sialosy! cholesterol, 493 astrocytes - b i n d i n g of s i a l o s y l c h o l e s t e r o l , 493 astrocytes - s y n t h e s i s a n d r e l e a s e of GABA, 567 autoradiography - incorporation of valine into proteins, 537

263

benzodiazepine r e c e p t o r s i t e s - m o d u l a t e d b y light, 257 benzodiazepine receptors - postnatal development, 257 b r a i n s t e m - l e v e l s of ~ - e n d o r p h i n and neuro~ensin, 97 ~-bungarotoxin b i n d i n g - r o l e of h i s t i d i n e residues, 521 ~-bungarotoxin binding - to nocotinic receptors, 521 butyrylcholine - decarboxylation, 201

caecum mucosa - release of substance P-immunoreactivity, 529 calcium channels - effect of ~-Agatoxins, 263 calcium effect on binding of presynaptic membranes and vesicles, 55 calcium - ganglioside interactions, 323 c a l c i u m - in s y n a p t i c p l a s t i c i t y , 323 calcium - intrasynaptosomal levels, 275 calcium-dependent - r e l e a s e of a c e t y l c h o l i n e a n d GABA, 43 cAMP - and dopamine f u n c t i o n s in t h e r e t i n a , 168 catecholamine production - in a d r e n a l c h r o m a f f i n cells, 2 2 9 ca~echolamine production - related to tyrosine supply, 229 catecholamine s e c r e t i o n - in c h r o m a f f i n cells, 501 Ca++/calmodulin-dependent p r o t e i n k i n a s e ii, 61 cerebral cortical neurones - s y n t h e s i s a n d r e l e a s e of GABA, 567 c e r e b r a l s p i n a l f l u i d - in S u d d e n I n f a n t D e a t h S y n d r o m e , 97 3-chloro-~-pheny!pyrazinemethanol inhibits monoamine oxidase, 37 c h o l i n e e f f l u x - r e l a t e d to a c e t y l c h o l i n e synthesis, 219 choline esters - and decarboxylation, 201 c h o l i n e e s t e r s - on d i m e t h y l c a r b a m y l - a c e t y l c h o l i n e s t e r a s e , 201 choline uptake - effect of monosialoganglioside GMI, 2 8 9 cholinergic neurones - in d i e n c e p h a l i c system, 583 cholinergic neuro~oxins - enhyl-choline and hemicholinium-3, 289 chromaffin cells - catecholamine formation, 229 chromaffin cells - catecholamine secretion, 501 chromaffin c e l l s - e f f e c t s of i n o r g a n i c t h i o p h o s p h a t e , 501 chromaffin cells - thiophosphorylated proteins, 511 chromaffin v e s i c l e m a t r i x , 511 ¢onus distans toxin - inhibits neurotransmitter release, 69 convulsant - action of 3-mercaptopropionic acid, 591 corticotropin releasing factor - increases tryp~ophan hydroxylase a c t i v i t y , 81 co-culture of neurones and astrocytes GABA release and synthesis, 567 co-localisation - of d o p a m i n e a n d GABA, 147 co-release - of a c e t y l c h o l i n e a n d GABA, 43 cytoskeletal prozeins e f f e c t of t r i - o - c r e s y l phosphate on p r o t e i n phosphorylation, 247 c - f o s m R N A - e f f e c t of M P T P r r e a t m e n t , 281

×i

xii

Index

cecarboxyla~ion - effect of choline esters, 201 decarboxylation - of acetylcholine and butyryicholine, 201 Dendro~$pis ancusticems venum - contains polypeptides t h a t a c t on m u s c a r i n i c receptor sites, 237 Dendroasmis anausticems characterisation of K + channel blockers, 553 development of h u m a n b r a i n - i n f l u e n c e of g a n g ! i o s i d e s , 421 developmen: - of vagal motor neurones, 119 diabetes - insulin receptor kinase activity, 487 diencephalic conduction system - acetylcholine metabolism, 583 differentia:ion - and gangliosides, 339 24R,25-dihydroxyvitamine D3 prevents aluminium-induced alteration of brain gangliosides, 391 dimethylcarbamyl-acetylcholinesterase - influence of c h o l i n e e s t e r s , 2 0 1 di-methyl pro!ine releasing hormone - stimulates phosphoinositide t u r n o v e r , 307 dopamlne functions - in t h e r e t i n a , 179 dopamlne functions - r e l a t e d to c A M P , 168 dopamlne neucones - in d i f f e r e n t reninas, 141 dopamlne receptors - in h u m a n f o e t a l b r a i n , 5 5 9 Ccpamine recep=ors - onzogeny, 559 dopamlne release, 147 dopamlne transport - effect by hypoxia, 385 dopamine transport - effect of gangliosides, 385 dopamine - co-localises with GABA, 147 dopamlne - different methods for !ocalisation, 140 dopamine - in ~ h e r e t i n a , 139 dopamine - mcduia~or in t h e r e t i n a , 193 ~-endorphin - in c e r e b r a l s p i n a l f l u i d , 97 ~-endorphin l e v e l in i n f a n t h u m a n brain, 93 enterochromaffin cells - release of substance P-immunoreactivity, enzyme immunoassay - of nerve growth faczor, 215 Escherichia c0!i - used to produce nerve grow:h factor, 129 e:hyl-choline - cholinergic neurotoxin, 289

fazty

acids

- effect

on

Na+/K+-ATPase,

529

12

GABA colocalises with dopamine, 147 GABA release from retina, 43 GABA synnhesis and release, 567 GABAergic mechanisms - of neurones co-cultured with astrocytes, ganglioside GMI inner ester - GM! lactone, 359 ganglioside - calcium interactions, 323 ganglioside - dependent f a c t o r , 401 ganglioside -of brain and vascular plexus, 365 gangliosides - and hypoxia, 385 gangliosides - distribution in A l z h e i m e r ' s disease, 433 gangliosides - effect of aiuminium, 391 gangliosides - e f f e c t on n e u r o n a l survival, shape and growth, 409 gangliosides - in d e v e l o p m e n t a n d a g i n g , 421 gangliosides - in h u m a n b r a i n , 421 gangliosides - in m e n i n g o e n c e p h a l i t i s , 365 gangliosides - in n e u r o n a l differentiation, 339 gangliosides - in s y n a p t i c plasticity, 323 gangliosides - influence on a c t i o n of s i a l o s y i cholesterol, 493 gangliosides - influence on d o p a m i n e uptake, 385 gangliosides - involvement in r e g e n e r a t i o n of o p t i c n e r v e , 371 gangliosides - protein interactions in g r a n u l e cells, 315 glycine recep=ors - in r e t i n a , 473 glycine receptors - modulation in N M D A t o x i c i t y , 473 glycine receptors - strychnine-insensitive, 473 GMI ganglioside - containing pho=oactivable azide, 315 GM! lacrone - prodrug of GM!, 3 5 9 granule cells - proteins interact with gangliosides, 315 -

-

-

567

Index

xiii

hemicholinium-3 - cholinergic neurotoxin, 289 hippocampus - synaptic plasticity, 441 histidine r e s i d u e s - in ~ - b u n g a r o t o x i n b i n d i n g site, 521 homocysteate - e f f e c t s o n a m i n o a c i d s , 75 homocysteine - e f f e c t s on a m i n o a c i d s in h i p p o c a m p u s , 75 hypoxia - beneficial e f f e c t of g a n g l i o s i d e s , 385 h y p o x i a - e f f e c t on d o p a m i n e u p t a k e , 385 insulin insulin insulin

r e c e p t o r k i n a s e a c t i v i n y - in d i a b e t e s , receptors - in r a t b r a i n , 487 - stimulation of kinase activity, 487

487

lipid peroxidation - in s y n a p n o s o m e s , 401 lipid peroxidation - reduced by ganglioside-dependent factor, long-term potentaition - involvement o f o p i o i d s , 441 long-term potentiation - and endogenous o p i o i d s , 457 long-term potentiation - and opioid peptides, 469 long-term potentiation - independence of NMDA receptors, 461

401

maturation of newborn rat brain - implications for Sudden infant Death Syndrome, 109 medulla oblongata of Sudden Infant Death children - binding of n e u r o t e n s i n and somatostatin, 113 melatonin - biosynthesis in t h e r e t i n a , 23 melatonin - f o r m a t i o n in p h o t o r e c e p t o r s , 25 melatonin - in t h e r e t i n a , 1 7 9 melatonin - regulation in t h e r e t i n a , 23 memory - involvement of o p i o i d p e p t i d e s , 449 meningoencephalitis gangliosides in b r a i n a n d v a s c u l a r p l e x u s , 365 3-mercaptopropionic acid - a convulsant, 591 3-mercaptopropionic acid - i n c r e a s e s b i n d i n g of q u i n u c l i d i n y l benzilate b i n d i n g , 591 microdialysis - of a m o n o a c i d s , 75 modulation - of acetylcholine metabolism, 583 modulation - of benzodiazepine r e c e p t o r s b y light, 257 modulator - of d o p a m i n e in t h e r e t i n a , 193 monoamine oxidase - inhibited by 3-chloro-~-phenylpyrazinemethanol, 37 monosialogang!ioside G M I - e f f e c t on c h o l i n e u p t a k e , 2 8 9 motor-neuron disease - presence of antiganglioside, 353 MPTP - induction of c - f o s m R N A , 281 MPTP = l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine, 281 mRNA of N-methyl-D-aspartate receptors - injected into Xenopu$ oocytes,299 mucosa - release of substance P-immunoreactivity, 529 muscarinic recepnor ligands - inhibition by polypeptides f r o m snake, 237 Na÷/K+-APTase - effect of stimulatory ligands, 13 Na+/K+-ATPase, 1 Na+/K+-ATPase - and synaptic ~ransmission, 19 Na+/K+-ATPase - effect of ouabain-like compounds, ii Na+/K+-ATPase - regulation by neurotransmitters, 1 nerve growth factor - analysis by enzyme im~unoassay, 215 nerve growth factor - expression in E s c h e r i c h i a coli, 1 2 9 neuronal calcium channels - blocked by ~-Agatoxin, 263 neuronal growth - effect of gangliosides, 409 neuronal s h a p e - e f f e c t of g a n g l i o s i d e s , 409 neuronal s u r v i v a l - e f f e c t of g a n g l i o s i d e s , 409 neurotensin - binding to medulla oblongata, 113 neurotensin - in b r a i n stem, 97 neurotensin - in c e r e b r a l s p i n a l fluid, 97 neurotransmitter release - inhibition of toxin from Conus neuro~ransmitners - i n f l u e n c e of N a ~ / K + - A T P a s e , 1 nicotinic acetylcholine receptors, 521 noradrenaline-organelles - from sympathetic g a n g l i a , 577 N-methyl-D-aspartane receptors - expressed in X e n o D u s o o c y t e , 2 9 9

d i s t a n s , 69

xiv

NMDA NY~A NMDA NMDA

Index

neurotoxicity - in r e t i n a , 473 neurotoxicity - involvement of g l y c i n e , 473 receptors - and opioids, 447 receptors - independence in l o n g - t e r m p o t e n t i a t i o n ,

461

o n t o g e n y - of d o p a m i n e r e c e p t o r s in h u m a n brain, 559 o n t o g e n y - of v a g u s n e r v e , 119 o p i o i d a c t i o n - r o l e of s e c o n d m e s s e n g e r s , 465 opioid pathways - involvement of N M D A r e c e p t o r s , 447 opioid peptides - and long-term potentiation, 441, 457, 469 o p i o i d p e p t i d e s - c o n t r o l of b r e a t h i n g , 103 opioid pepnides - s e i z u r e s a n d m e m o r y , 449 opioid receptor - peptidergic regulation, 441 opioid transmission - dysregulation in Sudden Infant Death opioids - excnatory effects, 463 o p i o i d s - in h i p p o c a m p u s , 441 optic nerve - regeneration, 371 o u a b a i n - e f f e c t on N a + / K + - A T P a s e , ii

S y n d r o m e , 103

[400 p r o t e i n - p h o s p h o r y l a t i o n in s y n a p t i c c y t o s k e l e t o n , 61 -4c0 protein s u b s t r a t e for Ca ** / c a l m o d u l l n' - e e~p e n d e n t protein kinase 61 peripheral neuropathies - antiganglioside antibodies, 353 phorbol esters - binding of presynaptic membranes and vesicles, 55 phosphoinositide t u r n o v e r - in a s t r o c y t e s , 307 phosphoinositide turnoverstimulated by thyrotropin releasing hormone, 307 phosphorylation of c y t o s k e ! e t a i p r o t e i n s - in s c i a t i c nerve, 247 phosphorylation - increases with tri-o-cresyl phosphate treatment, 247 photoreceptor - s i t e for m e l a t o n i n formation, 25 photorecepnors - retinomotor movements, 156 posnsynaptic density-enriched fractions - from different Drain regions, 61 potassium channel blockers - purification, 553 potassium channel blocking peptides, 553 presynaptic membranes - b i n d i n g to s y n a p t i c v e s i c l e s , 55 -

quantitative quinuclidinyl quinuclidinyl

autoradiography, 537 benzilate binding - increased by 3-mercaptopropionic b e n z i l a t e b i n d i n g - to c h o l i n e r g i c receptor, 591

acid,

591

r e c e p t o r - n i c o t i n i c type, 521 recombinant h u m a n n e r v e g r o w t h factor, 129 regeneration of o p t i c n e r v e - i n v o l v e m e n t of g a n g l i o s i d e s , 371 r e l e a s e - of d o p a m i n e , 147 retina - dopaminergic s y s t e m , 139 retina - glycine receptors, 473 retina - melatonin cycle, 179 retina - NMDA-induced neurotoxicity, 473 r e t i n a - r e l e a s e of a c e t y l c h o l i n e a n d GABA, 43 R U 3 8 4 8 6 - b l o c k s e f f e c t of c o r t i c o = r o p i n r e l e a s i n g factor, 81 sodium/potassium ATPase, see Na+/K+-ATPase synap:osomes - lipid peroxidation, 401 second-messengers - r o l e of o p i o i d a c t i o n , 465 seizures - involvement of o p i o i d p e p t i d e s , 449 serotonin - inhibits substance P-immunoreactivity r e l e a s e , 529 sialosyl cholesterol - b i n d i n g ~o a s t r o c y t e m e m b r a n e s , 493 siaiosyl cholesterol - interaction with gangiiosides, 493 siaiosyl cholesterol - interactions with plasma membrane astrocytes, 493 snake venum polypeptides - a c t on m u s c a r i n i c cholinergic sites, 237 snake venum - purification of K* c h a n n e l b l o c k e r s , 553 somatostatin - b i n d i n g s i t e s to m e d u l l a o b l o n g a : a , 113 spider venum zoxins - ~-Agatoxins block neuronal calcium channels, 263 s p i p e r o n e - b i n d i n g in h u m a n b r a i n , 5 5 9 s t r i a t u m - s p i p e r o n e b i n d i n g in h u m a n b r a i n , 559 strychnine-insensitive - glycine receptors, 473 substance P-immunoreactivity - release from enterochromaffin cells, 529

Index

xv

substance P-immunoreactivityrelease inhibited by serotonin and calcium free medium, 529 Sudden Infant Death Syndrome dysregulation o f o p i o i d t r a n s m i s s i o n in b r e a t h i n g , 103 Sudden Infant Death Syndrome - levels of neurotensin a n d ~- e n d o r p h i n c e r e b r a l s p i n a l f l u i d a n d b r a i n stem, 97 S u d d e n I n f a n t D e a t h S y n d r o m e - m a t u r a t i o n of t h e b r a i n , 109 S u d d e n I n f a n t D e a t h S y n d r o m e - ~ - e n d o r p h i n in b r a i n , 93 sympathetic ganglia - preparation of noradrenaline-snoring o r g a n e l l e s , 577 s y n a p ~ i c c o n n e c t i v i t y in t h e r e t i n a , 153 synaptic cytoskeleton - phosphorylation of P400 p r o t e i n , 61 s y n a p t i c p l a s t i c i t y - in h i p p o c a m p u s , 441 s y n a p t i c p l a s t i c i t y - r o l e o f g a n g l i o s i d e s a n d c a l c i u m , 323 s y n a p t i c v e s i c l e s - b i n d i n g t o p r e s y n a p t i c v e s i c l e s , 55 s y n a p t o s o m a l l e v e l s - o f c a l c i u m , 275 synaptosomes - acetylcholine s y n t h e s i s , 219 s y n a p t o s o m e s - e f f e c t o f ~ - A g a t o x i n s on c a l c i u m c h a n n e l s , 263 thiophosphorylated p r o t e i n s - in c h r o m a f f i n cells, 511 thyrotropin releasing hormone - stimulates phosphoinositide t u r n o v e r , 307 toxin - from snail inhibits neurotransmitter r e l e a s e , 69 tri-o-cresyl phosphate - increases phosphorylation of cytoskeletal proteins,247 tryptophan hydoxylase - activity increased by corticotropin releasing factor 81 t r y p t o p h a n h y d r o x y l a s e a c t i v i t y - in a m y g d a ! a , 81 t u m o r p r o t e i n s - i n c o r p o r a t i o n of v a l i n e , 537 tyrosine - supply related to catecholamine production, v a g a l m o t o r n e u r o n e s - d e v e l o p m e n t , 119 v a g u s n e r v e - o n t o g e n y , 119 v a l i n e - i n c o r p o r a t i o n i n t o t u m o r p r o t e i n s , 537 v a n a d i u m - e f f e c t o n N a + / K + - A T P a s e , 12 vesicles - noradrenaline-containing, 577 v e s i c l e s - o f c h r o m a f f i n cells, 511 XenoDus o o c y t e - e x p r e s s i o n of N - m e t h y l - D - a s p a r t a t e

229

receptors,

289